iiinova — where your digital self keeps evolving

Quentin Gouil @qgouil.bsky.social · 18/11/2025

Excited to share matchbox. It’s super fast and versatile to search for patterns in reads, I’m curious to see all the uses it will find! Congrats to @jakobschuster.bsky.social , co-supervisors @michaelbclark.bsky.social @mritchieau.bsky.social and team! www.biorxiv.org/content/10.1...

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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 11/11/2025

Powerful read processing with matchbox www.biorxiv.org/content/10.1101/202…

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Rob Patro @robp.bsky.social · 11/11/2025

Holy crap! This looks awesome. We've been working toward something just like this (github.com/COMBINE-lab/...), and matchbox seems great; and in Rust! Perhaps we've been scooped, but this looks amazing either way!

github.com

GitHub - COMBINE-lab/seqproc

Contribute to COMBINE-lab/seqproc development by creating an account on GitHub.

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Wai-Hong Tham @thamlab.bsky.social · 27/10/2025

Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙 Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski www.biorxiv.org/content/10.1...

biorxiv.org

alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing

Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...

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Quentin Gouil @qgouil.bsky.social · 24/10/2025

Excited to share our new preprint: alpseq - an open-source workflow to turbocharge nanobody discovery! 🦙 doi.org/10.1101/2025... This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group! Find alpseq at github.com/kzeglinski/a...

doi.org

alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing

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Quentin Gouil @qgouil.bsky.social · 25/09/2025

🚴‍♂️ I’m riding to make a difference: help me support cancer research 🎗️ I’m training for a ride and raising funds for cancer research, support and prevention. You can contribute via my fundraising page here: 👉 vicdiscovery.tourdecure.com.au/quentin-gouil Thank you for your support!

vicdiscovery.tourdecure.com.au

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Make a donation today to support VIC Discovery Tour 2025

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Quentin Gouil @qgouil.bsky.social · 16/09/2025

Long-read transcriptomics is advancing quickly, we benchmarked leading bulk and single-cell protocols in this awesome collaborative effort! We hope it will be a valuable resource for the community. Congrats @youyupei.bsky.social @mritchieau.bsky.social @michaelbclark.bsky.social and all!

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long-read-tools.bsky.social @long-read-tools.bsky.social · 29/08/2025

>1,000 long-read tools in the latest update! 🚀 Long-read trancriptomics heating up 🔥 long-read-tools.org

long-read-tools.org

long-read-tools

A catalogue of long read analysis tools

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WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 06/08/2025

Discovery: mRNA vaccine candidate blocks malaria from reproducing inside mosquitoes, cuts transmission by up to 99.7%. Built on cryo-EM insights into parasite’s fertilisation machinery. A key step towards elimination. In @science.org 🔗 www.wehi.edu.au/news/reveale...

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Wai-Hong Tham @thamlab.bsky.social · 01/08/2025

Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗 🦟 Transgenic parasites without Pfs230 D13D14 do not transmit 🦙 💉Nanobodies + mRNA induced antibodies reduce transmission New in @Science.org www.science.org/doi/10.1126/... #ScienceResearch #Malaria #WEHI

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MIG @mig-unimelb.bsky.social · 18/02/2025

🚨 We're hiring! 🚨 The School of Mathematics & Statistics, UniMelb seeks a scientist in Machine Learning in Omics to lead research in statistical methods for omics. 📍 MIG | 📅 By Apr 11 🔗 jobs.unimelb.edu.au/en/job/91945... #MachineLearning #Omics #DataScience #HigherEd #Mathematics #Statistics

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Wai-Hong Tham @thamlab.bsky.social · 17/02/2025

Interested in #malaria transmission and fertilisation? Check out our new work using cryo-EM of ENDOGENOUS sexual stage parasites to determine the Pfs230-Pfs48/45 fertilisation complex - please read & share! structures| nanobodies |human immune responses | mRNA-LNP www.biorxiv.org/content/10.1...

biorxiv.org

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Wolfgang Huber @wkhuber.bsky.social · 14/02/2025

Do you love software engineering for exciting biological applications, open science,open source, R, Bioconductor, modern web, cloud& ML technologies? We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Picture of the conference centre on the EMBL campus in Heidelberg

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Nadia Davidson @nadia-davidson.bsky.social · 10/02/2025

Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!

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