Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...

Waterfield and colleagues report the transcription factor RUNX1 expressed in mTECs profoundly influences the diversity of thymic mimetic cells that express tissue-specific antigens.

Abstract. Natural selection encodes learned information in the genome. Learned solutions may be tuned specifically to past challenges, failing in altered e

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Continuation of Modifications to Peer Review Practices NOT-OD-26-069. NIH

Cytokinetic abscission genes are linked to cancers and developmental disorders, but the consequences of disrupted abscission in vivo remain under-explored. Previously we showed that in the forebrain o...

Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In m...

STAT interviews with 30 respondents brought the unmistakably human impacts of federal science policy into sharp focus. Here are three of those stories.

Funding for national laboratories and important research projects would increase under the government’s plans.

ALT: a cartoon character says just take a look will you while holding a tablet

ALT: a woman in a suit and tie has the words wait what written on her face

Scientific journals love news-worthy results. Editors want to publish studies with novel data that scientists will eagerly read and cite in their own work. Because of this desire for novelty, studies ...

Original paper: https://rupress.org/jcb/article/225/1/e202503070/278464/Actomyosin-contractility-and-a-threshold-of Video summary by Camilla S. Teng (Jeffrey Bush Lab, University of California San…

Anchorage-dependent cells are cells that require physical attachment to a solid surface, such as a culture dish, to survive, grow, and reproduce.