Sign in

EPFL Brain Mind Institute

@epfl-brainmind.bsky.social
821 followers 16 following 70 posts

EPFL Brain Mind Institute researchers develop & deploy technology to gain fundamental insight into brain & spinal cord systems, exploiting this knowledge for new therapies for brain disorders & towards novel intelligent machines go.epfl.ch/brain

PostsRepliesMedia
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 28/09/2026
A new dataset from the lab of @epfl-brainmind.bsky.social professor Henry Markram includes 244 reconstructions and 641 curated recordings of juvenile rat cortical neurons, linked so researchers can examine structure and electrical behaviour in the same cells - doi.org/10.3389/fnin...
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 26/09/2026
We look forward to welcoming a new professor Lindsey Salay whose lab will work on how the brain combines sensory, social and internal signals to guide adaptive behaviours. actu.epfl.ch/news/appoint...
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 24/09/2026
A new mouse brain lipid atlas from the labs of @gioelelamanno.bsky.social & Giovanni D'Angelo reveals 500+ distinct biochemical territories or 'lipizones', that reflect brain anatomy & connectivity plus change in pregnancy. Read the paper: doi.org/10.1038/s415... & explore the atlas: lbae-v2.epfl.ch
110
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 23/09/2026
Congratulations to @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social for winning the 25th Eppendorf & Science Magazine Prize for Neurobiology!
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 07/09/2026
HCN channels help set electrical rhythms including neuronal excitability. But how does temperature affect them? A new study by Rajnish Ranjan in the Markram lab compares mouse, rat & human HCN channels, revealing conserved kinetics and faster gating at higher temperatures: doi.org/10.1113/EP09...
011
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 04/08/2026
Deep learning could help improve cortical visual prostheses - Michael Herzog’s lab in the @epfl-brainmind.bsky.social found that a deep neural network–based strategy reduced the number of phosphenes needed for object recognition, especially at low electrode densities: doi.org/10.1088/1741...
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 20/07/2026
CRISPR HDR genome editing uses a repair template. But the @mccabelab.org in @epfl-brainmind.bsky.social found these templates sneak into the #Drosophila genome uninvited, corrupting downstream results. Their fix is a template design that makes stray insertions easy to catch: doi.org/10.1371/jour...
131
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 19/07/2026
Why are some of us more willing to put in more effort & what changes when that fades? The Sandi @carmensandi10.bsky.social lab links effort-based motivation to mitochondrial health in D1 ventral striatum neurons. Males & females have the same deficit but via distinct routes: doi.org/10.1073/pnas...
011
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 19/07/2026
How does the brain know when a sensation should trigger an action? Ghaderi, Crochet & Petersen in the @epfl-brainmind.bsky.social find that whisker secondary motor cortex (wM2) is where context meets touch, predicting a mouse's lick within 30 ms of a whisker deflection: doi.org/10.1038/s414...
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 09/07/2026
Congratulations to Gioele La Manno @gioelelamanno.bsky.social upon receiving the the 2026 Boehringer Ingelheim Research Award at #FENS.
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 09/07/2026
Congratulations to Carmen Sandi @carmensandi10.bsky.social upon receiving the 2026 Chica and Heinz Schaller Foundation Award today at #FENS.
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 07/07/2026
Your eyes constantly move to hunt for information, a strategy known as infotaxis. New work from Prof. Mackenzie Mathis's lab @trackingactions.bsky.social shows mice do it too: in a VR task, they actively sought out the most informative views, adjusting as visual info changed doi.org/10.1016/j.cu...
1126
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 07/07/2026
The same touch can mean different things. New work from Carl Petersen's lab in the @epfl-brainmind.bsky.social mapped the cortical circuits underlying this in mice and found a surprise; the retrosplenial cortex was the first area to tell contexts apart after a whisker touch doi.org/10.7554/eLif...
000
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 09/06/2026
Do good vision test scores predict better performance on other vision tests? A new study by the @epfl-brainmind.bsky.social group of Michael Herzog says: not really. Weak correlations across tests suggest we may be measuring methods, not vision itself. Read more: doi.org/10.1016/j.is...
000
Reposted by EPFL Brain Mind Institute
McCabe Lab @mccabelab.org · 08/06/2026
Minis, aka spontaneous synaptic neurotransmitter vesicle release, was long dismissed as noise. Our new 📄 using optical electrophysiology shows minis are not spontaneous at all. They're an independent release modality regulated by Unc-5 & critical for synapse preservation 👉 doi.org/10.64898/202...
022
Reposted by EPFL Brain Mind Institute
Mackenzie Weygandt Mathis @trackingactions.bsky.social · 29/05/2026
Honored to share that I’ve been promoted to Associate Professor with tenure at @epfl-brainmind.bsky.social @epfl-ai-center.bsky.social (EPFL)! 🎉 Deeply grateful to my current and past incredible lab members, collaborators, and mentors who’ve made this journey possible. 🧠✨🙏🏼
121503
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 25/05/2026
Electrophysiological recording feature extraction is hard to standardise. Prof. Henry Markram's @epfl-brainmind.bsky.social lab introduces eFEL: an open-source, cross-platform library defining 90+ electrophysiological features for efficient, reproducible, FAIR analysis: doi.org/10.1093/bioi...
doi.org
eFEL: Electrophysiology Feature Extraction Library
AbstractMotivation. Electrophysiological recordings are essential in experimental and computational neuroscience, providing insights into neuronal excitabi
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 25/05/2026
New CmeCUT&Tag method from the lab of Fides Zenk @epign.bsky.social in @epfl-brainmind.bsky.social maps DNA methylation genome-wide both faster & cheaper. Validated across stem cells, organoids & tumours, its matches the gold standard of bisulfite sequencing doi.org/10.1038/s414...
000
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 22/05/2026
Congratulations to @epfl-brainmind.bsky.social professors Mackenzie Weygandt Mathis @trackingactions.bsky.social and Alexander Mathis @trackingskills.bsky.social on their well-deserved promotion to Associate Professor! actu.epfl.ch/news/appoint...
060
Reposted by EPFL Brain Mind Institute
Alexander Mathis @trackingskills.bsky.social · 21/05/2026
I‘m looking for postdoc candidates in computer vision and control theory (2 positions). Get in touch if you’re interested.
23014
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 04/05/2026
Can microglia be stimulated to help fight #Alzheimer’s disease (AD)? New work from the Gräff @graeffjohannes.bsky.social & Sanchez-Mut groups shows PM20D1, via its metabolite OLE, promotes microglial engagement with amyloid plaques and neuroprotection in AD models - doi.org/10.1038/s413...
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 04/05/2026
New work by Simone Astori in Carmen Sandi's @carmensandi10.bsky.social lab shows that nucleus accumbens medium spiny neurons rapidly tune their excitability to mitochondrial energy shifts via K-ATP channels, linking neuronal bioenergetics to effort-related motivated behaviour doi.org/10.1038/s413...
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 27/04/2026
Many motor tasks require precise coordination between multiple motor & sensory systems. New #Drosophila work by the @epfl-brainmind.bsky.social group of Pavan Ramdya reveals the centralized neural circuits necessary to solve antennal grooming synchronized motor-control - doi.org/10.1038/s414...
000
Reposted by EPFL Brain Mind Institute
Federation of European Neuroscience Societies - FENS @fens.org · 24/04/2026
🧠 Carmen Sandi | Chica and Heinz Schaller Foundation Award Lecture 🌟 At #FENS2026, join Prof. Carmen Sandi, École Polytechnique Fédérale de Lausanne, on 9 July! 🔗 Meet all the speakers: buff.ly/1EBdiLL
163
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 23/04/2026
Carl Petersen: Cortical circuits for whisker sensory perception—From barrel columns to brain-wide interactions doi.org/10.1016/j.co...
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 23/04/2026
Two new @epfl-brainmind.bsky.social group reviews: The lab of Alexander Mathis @trackingskills.bsky.social: The behavior biopsy: Interpreting animal behavior as embodied, situated, and hierarchical doi.org/10.1016/j.co...
0145
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 01/04/2026
Many congratulations to @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social!
020
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 01/04/2026
Novelty is not just about whats new, but also what feels new given past experience. New study from Sophia Becker in Wulfram Gerstner’s @epfl-brainmind.bsky.social lab posits a model showing how similarity between familiar and novel stimuli shapes exploration and learning - doi.org/10.1016/j.ne...
0196
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 11/03/2026
How does circuit structure shape neural activity? The lab of @epfl-brainmind.bsky.social Prof. Wulfram Gerstner shows that distinct neural circuits can produce similar low-dimensional dynamics, while retaining clear signatures in single neuron and population activity data: doi.org/10.1016/j.ne...
0154
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/02/2026
What if memory loss from aging or disease could be restored? The lab of @epfl-brainmind.bsky.social Professor Johannes Gräff @graeffjohannes.bsky.social shows that partial cellular reprogramming of engram neurons restores learning and memory to youthful levels in mice - doi.org/10.1016/j.ne...
120
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 02/02/2026
When objects are close together, seeing details is harder 👉visual crowding. @epfl-brainmind.bsky.social prof. Michael Herzog's lab shows that a single nearby object barely affects perception, but many can aid or impede it, depending on alignment, challenging current theories doi.org/10.1177/1747...
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 26/01/2026
Understanding how brain regions communicate to shape behavior requires realistic models. The @epfl-brainmind.bsky.social labs of Carl Petersen & Wulfram Gerstner show that adding biological features to neural networks improves the prediction of brain responses to stimulation doi.org/10.7554/eLif...
040
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 26/01/2026
Identifying individual wild animals is key for conservation. The lab of @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social uses AI and images of Alaskan brown bears to non-invasively identify individuals & their behavior across seasons & years doi.org/10.1016/j.cu...
071
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 14/01/2026
EPFL ELISIR apps now open go.epfl.ch/ELISIR. Fantastic opportunity for young neuroscientists to start an independent lab right after PhD, just like @epfl-brainmind.bsky.social ELISIR group leaders @jamespriestley.bsky.social & @ashleymaynard.bsky.social. www.youtube.com/watch?v=qjPD... 👉 April 1 26
go.epfl.ch
EPFL Life Sciences Early Independent Research Scholar (ELISIR)
From exceptional PhD directly to independent group leader
053
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/11/2025
@epfl-brainmind.bsky.social professor Michael Herzog's lab carried out a simulation study to identify how many visual elements are needed for object recognition by cortical visual prostheses, establishing a practical lower-bound phosphene estimate for more effective function: doi.org/10.1016/j.vi...
000
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/11/2025
The group of @epfl-brainmind.bsky.social professor Johannes Gräff @graeffjohannes.bsky.social show that altering histone acetylation enhances fear memory recall, while reducing it weakens recall, demonstrating a functional link to the activity of memory engram cells: doi.org/10.1002/hipo...
000
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 07/11/2025
Can memories be switched on and off, as in 'Eternal Sunshine of the Spotless Mind'? The team of @epfl-brainmind.bsky.social professor Johannes Gräff @graeffjohannes.bsky.social use CRISPR-based epigenetic control of Arc to reduce or enhance memories in mice: www.nature.com/articles/s41...
100
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 27/10/2025
Prof. Carmen Sandi's @carmensandi10.bsky.social group reviews the potential for modulation of metabolic pathways to treat anorexia nervosa - www.nature.com/articles/s41...
nature.com
Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain - Translational Psychiatry
Translational Psychiatry - Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain
020
Reposted by EPFL Brain Mind Institute
Federation of European Neuroscience Societies - FENS @fens.org · 20/10/2025
The Chica and Heinz Schaller Foundation and #FENS are thrilled to announce the winner of the Chica and Heinz Schaller Foundation Award in Translational Neuroscience 2026: Prof. Carmen Sandi (@carmensandi10.bsky.social)! 🧠 👉 loom.ly/Uh0TghU
192
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/10/2025
The group of @epfl-brainmind.bsky.social professor Henry Markram shows that glucose-dependent N-glycosylation drives variability in the Kv3.4 ion channel, regulating activity & cell excitability. N-glycosylation regulation may link neurological disorders & glucose metabolism: doi.org/10.1016/j.is...
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/10/2025
How do we weigh curiosity, effort, and reward? The labs of @epfl-brainmind.bsky.social professors Wulfram Gerstner & Michael Herzog find humans overexplore when seeking monetary reward, drawn to novel options even when more exploration offers no advantage. Explore the paper 👉 doi.org/10.1073/pnas...
041
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 16/10/2025
New study by the group of @epfl-brainmind.bsky.social professor Carmen Sandi @carmensandi10.bsky.social shows that three mitochondrial associated metabolites in the dmPFC/dACC brain region can predict mental effort choices - www.nature.com/articles/s41...
083
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 30/09/2025
Last chance to apply for the EPFL Neuroscience tenure track assistant professor faculty position - the deadline is tomorrow October 1. Submit now! go.epfl.ch/neurofaculty.
040
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 08/09/2025
Group of @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social + Giovanni D’Angelo lab, use MS imaging & a novel analytical framework to map the 4D distribution >100 lipids in zebrafish & find unexpected distributions 👉 unknown developmental roles - doi.org/10.1038/s415...
030
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 02/09/2025
Cataract surgery is the most common surgical procedure worldwide. The lab of @epfl-brainmind.bsky.social professor Michael Herzog shows that in addition to visual acuity, cataracts also affect low-level visual processing, which should be considered in ophthalmic clinical care doi.org/10.1167/jov....
010
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 26/08/2025
The group of @epfl-brainmind.bsky.social professor Carmen Sandi @carmensandi10.bsky.social shows Corticotropin-releasing Hormone (CRH) modulates the thalamic reticular nucleus brain region to affect sleep, linking CRH with sleep impairment due to stress and anxiety- www.nature.com/articles/s41...
051
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 18/08/2025
@epfl-brainmind.bsky.social Prof. Carmen Sandi's lab @carmensandi10.bsky.social show Urolithin A (UA), a gut microbiota-derived metabolite, can alleviate anxiety in rodents including behaviour, mitochondria & neuronal features. UA could be a new treatment for chronic anxiety doi.org/10.1016/j.bi...
262
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 18/08/2025
The group of @epfl-brainmind.bsky.social Prof. Michael Herzog (also + @carmensandi10.bsky.social) show that human social dominance, a key social interaction factor, is a stable personality trait, has reliable specific brain EEG markers which in females mirror those in males doi.org/10.1016/j.is...
041
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 18/08/2025
Action potential 👉 3 faculty opportunities to join EPFL neuroscience 1. Tenure Track Assistant Professor in Neuroscience go.epfl.ch/neurofaculty, 2. Tenure Track Assistant Professor in Life Sciences Engineering, or 3. Associate Professor (tenured) in Life Sciences Engineering go.epfl.ch/LSEfaculty
1113
EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 20/07/2025
We are happy to announce an opening for a Tenure Track Assistant Professor Faculty Position in Neuroscience at EPFL. Join our groups working on cellular & circuit neuroscience & neurocomputation - go.epfl.ch/brain. Application deadline is Oct 1 2025. Apply now 👉 go.epfl.ch/neurofaculty
010