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The Journal of Physiology

@jphysiol.bsky.social
1.3K followers 65 following 1.2K posts

The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.

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The Journal of Physiology @jphysiol.bsky.social · 1h
Enrique Velasco and collaborators found no evidence for homotopic #hyperalgesia to C fibre stimulation after transcutaneous high-frequency stimulation in humans 🧠 ⚙️ Read the #Research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 3h
How do alcohol, opioids, nicotine, cannabis & psychostimulants reshape brain circuits? 🧠 ⚙️ Submit your latest research to this special issue which focuses on drug-induced changes in neural and glial physiology and their links to behaviour 💊 🔬 🔗 physoc.onlinelibrary.wiley.com/hub/journal/...
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The Journal of Physiology @jphysiol.bsky.social · 23h
In this recent review, Volker Dietz and Linard Filli from @uzh-ch.bsky.social discuss the impact of the #brainstem in normal and impaired human movement control ⚙️ 🧠 Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 29/09/2026
Senior Editor Professor Paul Greenhaff discusses his career, his hopes for the future of physiology and his work with @physoc.bsky.social's Policy Team in this blog post, part of the #150voices of physiology series! 🎓️ 📣 Read it here👇️ www.physoc.org/blog/profess...
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Reposted by The Journal of Physiology
Experimental Physiology @expphysiol.bsky.social · 28/09/2026
🚨 LAST CHANCE TO APPLY 🚨 Applications for our Future Leaders Scheme close on 30 November. Gain valuable experience engaging with scholarly research, learn from established experts, and contribute to the scientific community. 🔗 buff.ly/2o4qDNq
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The Journal of Physiology @jphysiol.bsky.social · 29/09/2026
#Research by Parisa Iloun and collaborators examines sublayer- and pathway-specific control of #CA1 input processing by VIP #interneurons 🔬 🧠 Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 28/09/2026
'Integrating vascular microstructure into coronary physiology: Beyond autoregulation' Clarissa Campo Dall'Orto examines the recent work of Eden et al. (2026) in this #JournalClub article 💭 ✍️ Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 28/09/2026
In this study, Nicole Sarah Holliger and collaborators from @uzh-ch.bsky.social investigated the involvement of the #reticulospinal system in the control of #locomotion 🧠 🔊 Read the paper👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 28/09/2026
In this recent review, Nicole Welch from @clevelandclinic.bsky.social and colleagues examine Hypoxia-inducible factor-1a (#HIF1a) as a context-dependent integrator of #metabolic stress in skeletal muscle🧬 🔎 Read the paper👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 26/09/2026
'The 21-nanometer window: How #endothelial pores reshape our understanding of #antigen dissemination' Check out this #JournalClub by Eduardo Rodrigues and co-authors where they examine the recent work of van Helden et al. (2026) ✍️ 📖 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 26/09/2026
'A shorter aPTT during acute psychological stress does not necessarily indicate contact pathway activation' suggest Zhikun Wang and Ying Huang in this recent #LetterToTheEditor✉️ 💡 Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 26/09/2026
Recent #research by Ranjan K. Roy and collaborators examines heart failure-induced reprogramming of salt-evoked #neurovascular coupling in the rat #hypothalamus 🧠 🔎 Read the findings💡 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 25/09/2026
'From central to #pulmonary capillary blood volume: Evidence for a non-linear relationship with pulmonary diffusing capacity' Ronan M. G. Berg highlights the recent work of D'Souza et al. in this #Perspective article 💭 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 25/09/2026
Phil Walker from @wrightstateu.bsky.social and colleagues conclude that efficacy of sodium channel blockers in treating #myotonia is independent of action potential sodium current block 🔬 ⚡️ Read the findings💡 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 25/09/2026
In this study, Evgeniia Motanova from @unipd.bsky.social and collaborators investigated preserved #mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults 🛌 🔬 See more👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 24/09/2026
'Pre-conditioning against cachexia: How prior exercise enhances metabolic resilience during cancer' Swarali Paranjape and Sena Yamamoto examine the recent work of Stavroula Tsitkanou and colleagues in this #JournalClub article💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 24/09/2026
New research by Daniel Z. Kruse from @au.dk and colleagues observes that #piperine disrupts the OFF state of the resting thick filament of rat skeletal #muscle, enhancing dynamic #contractility in a fibre-type-dependent manner 🔎 ⚡️ Read it here! physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 24/09/2026
Yongxiu Yang and collaborators introduce a multiscale PBPK-PD model of #oxytocin-induced #uterine excitation and contraction 🔬 💻️ Read the #research📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 22/09/2026
In this study, Andrew W. D'Souza from @ualbertadom.bsky.social and colleagues investigated differential effects of central blood volume loading and unloading on #pulmonary diffusing capacity in humans 🫁 🔎 Read the conclusions👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 22/09/2026
As part of @physoc.bsky.social's 150th anniversary celebrations, Jphysiol Regional Editor Professor Yoshihiro Kubo discusses his career, his hopes for the future of physiology and his work with the Society. 🎓️ Read the blog!👇️ www.physoc.org/blog/profess...
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The Journal of Physiology @jphysiol.bsky.social · 22/09/2026
Featuring on the cover of the latest issue, Natalia Murataeva and colleagues conducted this study into N-Arachidonoyl-phosphatidylethanolamide phospholipase D activation by muscarinic receptors 🔬 💉 Read the #research📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 21/09/2026
Uwe Proske from @monashuniversity.bsky.social and Bernhard M. Weber from @dlr-en.bsky.social offer this reply to Han et al.'s letter to the editor on ‘Repositioning the reposition tasks as proprioceptive’📣 ✉️ Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 21/09/2026
#Research by Clément Vitrac from @uzh-ch.bsky.social and colleagues observes that impaired peri-infarct long-term potentiation in anaesthetized rats suggests alternative mechanisms of post-#stroke recovery🧠 🔬 Read the findings💡 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 21/09/2026
Takao Shimayoshi and colleagues present integrative simulation analysis of #myocardial ischaemia–reperfusion injury 💻️ 🔬 Read the #research article👇️ 📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 19/09/2026
'Repositioning the reposition tasks as proprioceptive' Jia Han and colleagues write this Letter to the Editor discussing the recent Opinion piece by Proske & Weber (2026) ✉️ ✍️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 19/09/2026
'Extreme makeover, heart edition: Determinants of exercise-induced cardiac remodelling in middle age' Read this recent #JournalClub from Masiha Behroozian from @utoronto.ca and co-authors as they examine the work of Hedge et al. (2026)✍️ 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 19/09/2026
DEADLINE APPROACHING⏰️ Call for papers on #chemoreception and #homeostatic control📍 ⚙️ Topics include oxygen and CO₂/pH sensing, carotid body physiology, chemoreceptor dysfunction, chemoreflex interactions, intermittent hypoxia, and more. 🔗 physoc.onlinelibrary.wiley.com/hub/journal/...
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The Journal of Physiology @jphysiol.bsky.social · 18/09/2026
#Research by Floor W. van den Dolder from @amsterdamumc.bsky.social and colleagues observes that early-stage #myocardial changes are not aggravated by Western #diet or #ageing in Mybpc3 c.2373insG heterozygous mice 🫀 🔬 Read the work👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 18/09/2026
Roger Kissane from @liverpooluni.bsky.social and co-authors ask the question 'How well does quantifying ‘capillary supply’ assess oxygen transport capacity in skeletal muscle?' in this recent #Opinion article 💭 Read it here: 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 18/09/2026
This study by Ruchi Bhagat from @pennstateuniv.bsky.social and colleagues observes that #oestrogen modulates stress-induced vagally-dependent #gastric responses to oxytocin 🔎 🧠 Read the #research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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Reposted by The Journal of Physiology
The Physiological Society @physoc.bsky.social · 17/09/2026
Our #PeerReview team's expertise, commitment & care sits at the heart of the Society’s journals & the communities we serve. Lucinda Periac-Arnold (Associate Director of Publishing @physoc.bsky.social) shines a spotlight on the team & our peer review communities ⬇️ www.physoc.org/blog/celebra...
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Celebrating Peer Review Week 2026
Celebrating our indefatigable peer review team, whose expertise, commitment and care sit at the heart of the Society’s journals.
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The Journal of Physiology @jphysiol.bsky.social · 17/09/2026
Stavroula Tsitkanou from @harvardmed.bsky.social explains her recent findings that #exercise may help protect against cancer-related muscle wasting and could even slow tumour growth 💡 🔬 Check out the #PhysiologyShort here!👇️ www.youtube.com/watch?v=1Tm_...
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The Journal of Physiology @jphysiol.bsky.social · 17/09/2026
Following their presentation at AuPS 2025, Daniel J. Ham from @biozentrum.unibas.ch and co-authors examine what treatments for age-related muscle wasting should target 🔎 🎯 Read the review👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 17/09/2026
🎓️ EDITOR'S CHOICE🎓️ Hua and colleagues showed that #FGF21 improved mitochondrial function and evidence of senescence in adipose tissue. Further, exogenous FGF21 could reverse the adverse effects of a high protein diet on hepatocytes. Read it here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 16/09/2026
In this recent review, Esau Mhandu from @aucklanduni.bsky.social and colleagues provide the first narration and collection of the various #techniques applied to load isolated #heart preparations 🫀 ⚙️ Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 16/09/2026
New issue now live! 📖 The cover art, taken from the work of Natalia Murataeva et al., depicts the lacrimal gland of female mouse and shows that fatty acid amide hydrolase is expressed in all acini 🔬 💉 Read all articles here👇️ physoc.onlinelibrary.wiley.com/toc/14697793...
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The Journal of Physiology @jphysiol.bsky.social · 16/09/2026
Rebecca L. Brady and co-authors observed that #thyroid antibody positivity in #pregnancy is associated with altered reproductive hormone concentrations and placental growth in Lewis rats 🔬 💉 Read the #research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 16/09/2026
Nasimi A. Guluzade and colleagues from @westernu.ca conclude that exercise hyperpnoea requires a feedforward exercise stimulus constrained by inhibitory #chemofeedback from rest to exercise to minimize hypocapnia🫁 ⚙️ Read the study👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 15/09/2026
Gabriel Calheiros Antunes from @unicampoficial.bsky.social and co-authors examine the work of Bushman et al. (2026) in this #JournalClub article 🔗 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 15/09/2026
Chaopeng Ou and co-investigators found that #METTL3-mediated m6A modification of circMtmr7 contributes to paclitaxel-induced peripheral #neuropathy in the dorsal horn🧠 🔬 Read the #research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 15/09/2026
'Old dog, new trick: #Charybdotoxin as a novel #ryanodine receptor blocker' Zsuzsanna Édua Magyar and colleagues identify K27N ChTX as a selective RyR inhibitor and a promising scaffold for future drug design 💊 🔬 Read the #Research👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 14/09/2026
This review by Kimberley M. Mellor from @aucklanduni.bsky.social and colleagues explores the emerging potential of #circRNAs as novel therapeutic targets in #cardiometabolic disease, building on the AuPS 2025 presentation 🔬 🫀 Read the article👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 14/09/2026
'Pain relief but #respiratory depression: Insights into the dark side of #opioid overuse' Daniel B. Zoccal offers this #Perspective on the recent research by Kalajian et al. (2026) 💭 ✍️ Read it here👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 11/09/2026
'Publish or perish, but at what cost?' Vaughan G. Macefield from @monashuniversity.bsky.social offers this #Perspective on the recent Opinion article by Bossi (2026), examining the hidden personal costs in (exercise) physiology 💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 11/09/2026
Luke Stoneback from @umich.edu and colleagues investigated structural determinants of quadriceps #atrophy following #ACL injury, providing evidence for fibre atrophy without fibre loss or overt peripheral denervation 🔬 🔎 Read the study👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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Reposted by The Journal of Physiology
Wiley Life Sciences @wileylifesci.bsky.social · 08/09/2026
🎊Congratulations to Georgia S Clarke, winner of the Inter-organ Prize from @jphysiol.bsky.social. Her study shows pregnancy and a high-fat, high-sugar diet each dampen gastric nerves that signal fullness, with no extra effect when combined. 🔗 bit.ly/3TF8S2y
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The Journal of Physiology @jphysiol.bsky.social · 10/09/2026
In this study, August Lomholt Kvistad from @ucph.bsky.social and co-investigators observed that #transcranial direct current stimulation enhances delayed retention after 5 days of lower-limb #motor skill learning ⚙️ 🧠 Read the article 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 10/09/2026
Research by Nelson Chang from @westernu.ca and colleagues finds that Stathmin-2 mediates #paracrine hormone regulation of #glucagon through lysosomal trafficking in αTC1-6 cells 🔬 ⚙️ Read the article 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 09/09/2026
'Fast and slow skeletal muscle: Different overall activation levels and kinetics of myosin motors underlie muscle type-specific contractile properties' Daniel Z. Kruse from @au.dk et al. examine the work of Hill et al. (2026) in this #JournalClub 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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The Journal of Physiology @jphysiol.bsky.social · 09/09/2026
J. Philip Karl and co-authors observed that increasing gut short-chain fatty acids protects #intestinal barrier function but does not spare muscle #glycogen or impact #aerobic performance 🔬 🔎 Read the study👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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