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Ewa Zarnowska

@ewadorotaz.bsky.social
765 followers 1.6K following 117 posts

Ph.D. | Ex-Neuro & Ephys | Neuroscience | Lasers, Microscopes, Quantum | Coherent Corp. | Opinions mine

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Ewa Zarnowska @ewadorotaz.bsky.social · 12/09/2026
In honor to people who died in the terror. 25 years…
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Ewa Zarnowska @ewadorotaz.bsky.social · 07/09/2026
📣 Our abstract, “Enhanced High-Speed In Vivo Voltage Imaging Through Engineered Two-Photon Excitation,” was selected for #SfN26 NANO44 symposium: Imaging and Recording Neural Activity. Nov. 18, 2026 | 8:00–11:30 AM Abstract #4797 Thank you to my industrial team and academic collaborators! 🙌
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Nicole Rust @nicolecrust.bsky.social · 28/08/2026
Oh wow! @thetransmitter.bsky.social amplified recent Bsky chatter about the dire US grant landscape. Thank you, @emilysingerneuro.bsky.social 🙏.
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Peter Rupprecht @ptrrupprecht.bsky.social · 18/08/2026
Interesting work from the lab of Na Ji on how axial imaging resolution (3.5- 20 um) affects the extraction of accurate neuronal signals. Very instructive! www.biorxiv.org/content/10.6...
biorxiv.org
High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations
Two-photon calcium imaging is a standard tool for measuring neuronal population activity in vivo , yet how axial resolution, sensor expression strategy, and analysis pipeline jointly affect data accur...
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Ewa Zarnowska @ewadorotaz.bsky.social · 24/08/2026
(1-3) In recent bioRxiv article from Cristina Rodriguez's lab @Yale the authors measured both GDD and third-order dispersion (TOD) directly at the objective focal plane at 1300 and 1600 nm. #3P #multiphoton biorxiv.org/content/10.6...
biorxiv.org
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Ewa Zarnowska @ewadorotaz.bsky.social · 15/08/2026
Attended, made many new friends, learned new things… quantum physics is applicable! Thanks to the organizers for a great time. quantum.utdallas.edu/tqs2026/
quantum.utdallas.edu
Texas Quantum Summit 2026
Overview The Texas Quantum Summit 2026 brings together leaders across academia, industry, and government to accelerate the development and deployment of quantum technologies in Texas and beyond. Build...
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Ewa Zarnowska @ewadorotaz.bsky.social · 11/08/2026
I hope you’ll have a chance one day to see the images captured with Ventana. Also offered with its holographic optogenetics option and supported with Monaco laser. Ventana truly offers a window into the brain at scale! And the brilliant people behind it are another reason why it is so special. 🚀🧠🥳🤓
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Ewa Zarnowska @ewadorotaz.bsky.social · 10/07/2026
Glad I took this selfie before poster session opened this morning. It started at 9 and then it was 1 pm quickly. I did not drink, I did not eat. Thank you all who stopped by my poster at #FENS2026. I loved to talk to you all about lasers. Happy imaging.
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Ewa Zarnowska @ewadorotaz.bsky.social · 09/07/2026
Very interesting session this morning at #fens2026 on All-optical voltage imaging for neuronal circuits dissection. Few questions - how much more improvement can come from optimizing excitation source vs engineering better sensors? Are newer GEVIs shifting 2p excitation away from 920-940 nm range?
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Ewa Zarnowska @ewadorotaz.bsky.social · 08/07/2026
At #fens2026 and available to brainstorm with you how to improve two-photon image quality for fast imaging with photons craving fluorescent probes. Send me a msg and let’s chat indoors over iced coffee! Outdoor temp reached 37 C! 🫠
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Adam Bowman @adam-bowman.bsky.social · 09/06/2026
Excited to share our first lab preprint! We enabled fast wide-field FLIM with low noise and high dynamic range. We built compact resonant modules for EO-FLIM that fit into your hand and developed methods to capture multi-exponential phasor plots at up to 500 Hz. www.biorxiv.org/content/10.6...
2.5 x 2.5 x 5 in
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Ewa Zarnowska @ewadorotaz.bsky.social · 29/06/2026
Great few days at @mblscience.bsky.social supporting Neurobiology and NSB courses. It’s always exciting to see how ultrafast laser technology help enable new #neuroscience imaging methods. A big thank you to organizers, instructors, students, Coherent and others for making this event spectacular.
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Ewa Zarnowska @ewadorotaz.bsky.social · 22/06/2026
I’m going to spend a couple of days this week at @mblscience.bsky.social. Cool place, cool people and great science.
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Spencer LaVere Smith @spencerlaveresmith.bsky.social · 12/06/2026
If you're not replacing your PMTs every 6 months, you might as well opt for SiPMs. src: www.nature.com/articles/s41... sipm: opg.optica.org/oe/fulltext.... www.nature.com/articles/s41...
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Nikolas Karalis @nikolaskaralis.bsky.social · 11/06/2026
With #FENS2026 just around the corner, our unofficial @fens.org abstract explorer is back: fens2026.neuronaldynamics.eu • Search abstracts by author, keyword, affiliation, and more • Discover related work using abstract similarity • Save favorites, add notes and tags, and build your own itinerary
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Ewa Zarnowska @ewadorotaz.bsky.social · 11/06/2026
Heading to Barcelona for my very first FENS! 🧠✨ Excited for the symposia, nerding out at posters, and presenting mine (PS07-10AM-005, Advanced Two-Photon Imaging Techniques, come say hi!). Also accepting applications for churros con chocolate buddies :) #FENS2026
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Ewa Zarnowska @ewadorotaz.bsky.social · 04/05/2026
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Salil Bidaye @salilbidaye.bsky.social · 04/05/2026
Here’s our latest preprint on uncovering neural control of a coordinated walking pattern! doi.org/10.64898/202... (author-list jumbled, see pdf for corrected). Video shows the central paradigm in this study, we optogenetically induce walking in headless flies and sequentially reduce proprioception.
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Ewa Zarnowska @ewadorotaz.bsky.social · 02/05/2026
Back from #OpticaBiophotonics26. I had an opportunity to share how we think about lasers and our laser solutions for emerging imaging applications.
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Ewa Zarnowska @ewadorotaz.bsky.social · 02/05/2026
Multimodal alignments of in vivo imaging and spatial biology datasets at cellular resolution #mini2p #Axon920 #laser www.biorxiv.org/content/10.6...
biorxiv.org
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Ryan Fink @finkryan.bsky.social · 24/04/2026
PinkyCaMP is finally published!! My first paper co-first authored with @sikmys.bsky.social where we make a great optogenetic and multiplex compatible red calcium indicator. Thank you to @massecklab.bsky.social and @campbell-lab.bsky.social for guiding this journey www.nature.com/articles/s41...
nature.com
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities - Nature Methods
PinkyCaMP is a red genetically encoded calcium indicator with improved brightness and photostability. Derived from mScarlet, it does not exhibit photoswitching upon blue light illumination and is ther...
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Spencer LaVere Smith @spencerlaveresmith.bsky.social · 24/04/2026
Open-source modular FPGA system for two-photon mesoscope: multiarea, multidepth neural activity recording. @riichirohira.bsky.social et al. present high throughput 2p calcium and what is maybe the largest field-of-view 2p fluorescence lifetime imaging (FLIM) data. doi.org/10.1117/1.NP...
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Ewa Zarnowska @ewadorotaz.bsky.social · 21/04/2026
I spent a bit more time thinking about this pre-print biorxiv.org/content/10.6... 👉3P isn't about more laser power. It's about the right rep rate, one pulse per pixel, and laser stability. If you are not measuring pulse-to-pulse noise you're not measuring your biology.
biorxiv.org
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Ewa Zarnowska @ewadorotaz.bsky.social · 14/04/2026
Practical optimization for three-photon microscopy to allow larger field of view and faster calcium imaging (10-30 Hz) www.biorxiv.org/content/10.6...
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Ewa Zarnowska @ewadorotaz.bsky.social · 05/04/2026
Easter time with my husband while our daughter is studying in PA
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Ewa Zarnowska @ewadorotaz.bsky.social · 05/04/2026
Back from #FOM2026. In multiphoton microscopy space label-free imaging, and spectroscopy in structural and metabolism biological imaging stood out. I’m excited to grow and support this space too.
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Yvette Fisher @yvetteefisher.bsky.social · 15/12/2025
*First preprint from our lab* !!!!! How does the brain learn to anchor its internal sense of direction to the outside world? 🧭 led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman: “Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6... Thread ⬇️
Schematic of how ER-EPG plasticity enables the bump of activity in EPGs to accurately track visual cues. As a fly makes a counter-clockwise turn (top to bottom) it will view visual cues (e.g. the sun) from a new angle and the EPG activity bump (red) will swing clockwise around the network by integrating self motion signals with these visual inputs. When the fly faces a different angle, distinct visual ER neurons are active. Plasticity forms a trough of weak synapses (large circles - strong synapses, small circles - weak synapses) that allow ER neurons with distinct visual tuning to move the EPG bump via disinhibition.
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Tommaso Patriarchi @tpatriarchi.bsky.social · 26/02/2026
The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...
doi.org
Next-generation multicolor indicators for in vivo imaging of norepinephrine - Nature Methods
Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...
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Christiane Grimm @cgrimm.bsky.social · 13/02/2026
We are finally online 🥳 What a fantastic adventure with @rrsims, the @emilianilab.bsky.social and all co-authors from IdV Paris #TwoPhoton #Voltagers #Holography #Rhodopsins
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Ewa Zarnowska @ewadorotaz.bsky.social · 13/02/2026
😎I'm delighted to announce that Coherent Corp. will be exhibiting at Sunposium Conference (mpfi.org/events/sunpo...) on Mar 09 - 11, 2026 in West Palm Beach. 🤩Attend my presentation Monday, March 10, board #101. 🤝Schedule a 1-1 with me to talk about your next microscopy projects. #neuroscience
mpfi.org
Sunposium Conference – Max Planck Florida Institute for Neuroscience
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Blake Russell @neurorussell.bsky.social · 26/01/2026
Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization: doi.org/10.1117/1.NP...
doi.org
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Kevin Dean @kevin-dean.bsky.social · 05/02/2026
In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...
doi.org
A high-resolution, easy-to-build light-sheet microscope for subcellular imaging
An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.
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Marco A. Maximo Prado @maximoprado.bsky.social · 06/02/2026
#fluorescencefriday distribution of microglia in the whole brain
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Amit Agarwal @agarwal-neurolab.bsky.social · 02/01/2026
We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
cell.com
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which cal...
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Abhi Aggarwal @abhiaggarwal.bsky.social · 23/12/2025
iGluSnFR4 is now available @natmethods.nature.com www.nature.com/articles/s41... Glutamate indicators with increased sensitivity and tailored deactivation rates 🧪
nature.com
Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...
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Ewa Zarnowska @ewadorotaz.bsky.social · 05/02/2026
We are delighted to sponsor both the GRC and GRS meetings, supporting innovative science and the next generation of leaders in basal ganglia research. #CoherentCorp #GRCBasalGanglia
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Ewa Zarnowska @ewadorotaz.bsky.social · 05/02/2026
❄️ Now I understand why people rave about Winter Conferences. I attended one last week and am still under the influence of the fantastic conversations, presentations, and mountain views. #neuroscience
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Ewa Zarnowska @ewadorotaz.bsky.social · 16/01/2026
On my way to BIOS and Photonics West in San Francisco. There will be many interesting presentations from Coherent (see the list under link below). Pick and choose something to match your interests! See you soon! #BIOS26 #PW26 www.coherent.com/events/photo...
coherent.com
Photonics West 2026
Photonics West is the premier photonics and laser exhibition featuring the latest advances in lasers, biomedical optics, optoelectronics, and more.
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Ewa Zarnowska @ewadorotaz.bsky.social · 13/01/2026
🔬 What’s next for ultrafast laser sources in multiphoton microscopy? Let's meet at BIOS on January 18, 2026 | 3:25 PM - 3:40 PM PST | Room 160 (Moscone South, Upper Mezzanine) and discuss! #BIOS26 #PhotonicsWest #UltrafastLasers #Microscopy #Photonics @spie.org spie.org/photonics-we...
spie.org
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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 14/12/2025
Two-photon imaging of pulsating brain activity in a #zebrafish larva that's having a seizure. Credit to Dr. Dominic Burrows. #ZebrafishZunday 🧪
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Ewa Zarnowska @ewadorotaz.bsky.social · 13/11/2025
I’m already in San Diego and participating first-hand in a bunch of exciting #sfn25 satellite events!
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Wendy Xin @droligo.bsky.social · 29/10/2025
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!
A flyer displaying the same information as written in the post, with two images of two astrocytes around a blood vessel and one newly formed oligodendrocyte, along with logs our sponsors Avantor and Plasmidsaurus.
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Ewa Zarnowska @ewadorotaz.bsky.social · 30/10/2025
#SfN25 is packed with amazing science and networking opportunities. Cannot wait! The power of coming together has never been more important. #Neuroscience #Microscopy #2Photon #3Photon #1Photon
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Ewa Zarnowska @ewadorotaz.bsky.social · 29/10/2025
💜 Great day at Harvard Medical School! Don't be sorry if you missed the workshop, customers presentations and tech talks. Reach out with questions.
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Ewa Zarnowska @ewadorotaz.bsky.social · 27/10/2025
🚀 Join us at Harvard Med! Discover how miniature multiphoton imaging is enabling neuroscience in freely moving animals. 🧠 Miniature Multiphoton Systems for Neuroscience Workshop 📍 Warren Alpert 236, 220 Longwood Ave 📅 Oct 27 | 12:00–15:00
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Alex @alexattinger.bsky.social · 24/10/2025
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social) doi.org/10.1101/2025...
doi.org
Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...
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Sarah @tinytunney.bsky.social · 18/10/2025
"There's no shortage of reasons these days to be angry or afraid. But look around you right now and you'll see tens of thousands of reasons to keep the faith and keep going. This is the America we know to be possible." —Mayor Michelle Wu, Boston No Kings Rally 🚫👑 #NoKings
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Dr. Anna Radke @aradprof.bsky.social · 17/10/2025
The microscopy core at Miami University is searching for a new director. Please consider sharing this job posting! miamioh.wd5.myworkdayjobs.com/en-US/miamio...
miamioh.wd5.myworkdayjobs.com
Director of the Center for Advanced Microscopy and Imaging
Job Title Director of the Center for Advanced Microscopy and Imaging Department Biology Department JM Worker Type Regular Pay Type Salary Position Salary Minimum $60,000 Position Salary Maximum $75,00...
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Stu Cantrill @stuartcantrill.com · 13/10/2025
‘Economics Nobel prize won by researchers who showed how science boosts growth’ by @philipcball.bsky.social in @nature.com www.nature.com/articles/d41...
Screenshot that reads:

The award "underlies the importance in investing in science for innovation and long-term economic growth", says economist Diane Coyle of the University of Cambridge. "It's great to see the Nobel prize recognize the importance of this topic," adds innovation policy researcher Richard Jones of the University of Manchester, UK. "It's important that economists understand the conditions that lead to technological progress," he adds. The winners, says Coyle, "have long been on people's list of potential candidates".
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Arnd Roth @arndroth.bsky.social · 23/09/2025
Check this out if you're interested in causal neuroscience and/or brain-machine interfaces www.cell.com/cell-reports...
cell.com
A real-time all-optical interface for dynamic perturbation of neural activity during behavior
Zhang et al. develop a system that reads activity from individual neurons in real time and uses holographic light patterns to control specific neurons in mice, enabling automated, all-optical experime...
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