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Tuan Bui

@tuanbuilab.bsky.social
319 followers 279 following 17 posts

Neuroscientist, spinal cord and motor control, Chair (why not?) of the Department of Biology at the University of Ottawa bui-lab.com

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Reposted by Tuan Bui
Ariel Levine @ariellevine.bsky.social · 04/02/2026
Want to come do a postdoc with us? We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
Next, looking at changes in calcium current in primary motoneurons during zebrafish development, published in Neuroscience Letters www.sciencedirect.com/science/arti...
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
Reposting Stephanie Gaudreau's new papers into how ion channel changes shape motor maturation in zebrafish without the institutional walls. 1st, the Journal of Physiology paper looking at opposite changes in the M-current and persistent Na current physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com
Distinct developmental dynamics of opposing persistent currents shape motoneuron firing during motor maturation of zebrafish
Abstract figure legend During the first few days of development, zebrafish acquire the ability to produce increasingly refined movements that rely progressively less on the activity of primary motone....
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
Characterization of calcium currents and their contributions to firing behaviour of primary motoneurons in developing zebrafish Gaudreau and Bui www-sciencedirect-com.proxy.bib.uottawa.ca/science/arti...
www-sciencedirect-com.proxy.bib.uottawa.ca
Réseau de bibliothèques - Library Network
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
Distinct developmental dynamics of opposing persistent currents shape motoneuron firing during motor maturation of zebrafish - Gaudreau and Bui - The Journal of Physiology - Wiley Online Library physoc-onlinelibrary-wiley-com.proxy.bib.uottawa.ca/doi/10.1113/...
physoc-onlinelibrary-wiley-com.proxy.bib.uottawa.ca
Réseau de bibliothèques - Library Network
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
As exciting, former PhD student, Stephanie Gaudreau, has just published 2 more first-authored papers. They describe her tremendous work showing specific developmental changes in ion channels of primary motoneurons of zebrafish. She shows that these changes affect firing properties AND motor output.
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Tuan Bui @tuanbuilab.bsky.social · 01/02/2026
Huge week for the lab. Firstly, we received a CIHR project grant to study the role of spinal dI3 neurons in recovery of locomotor activity after spinal cord injury. We're very excited to tackle these projects to bring new insights to inform how to treat loss of motor function after SCI.
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Reposted by Tuan Bui
BeatoLab @beatolab.bsky.social · 02/09/2025
An absolutely lovely paper, if I may say so... Joint effort from @tuanbuilab.bsky.social, Turgay Akay, and the Beatostone lab, aka Rob Brownstone's lab and mine
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Tuan Bui @tuanbuilab.bsky.social · 02/03/2025
Pubmed is down and i pray it is a technical rather than political issue. This could be a serious setback for basic and applied research
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Tuan Bui @tuanbuilab.bsky.social · 06/02/2025
If you're interested in spasticity, we've just published a reliable way to optogenetically induce hindlimb spasticity after spinal cord injury. All the credit goes to PhD graduate Sara Goltash and postdoc @alaliberte.bsky.social www.sciencedirect.com/science/arti...
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Tuan Bui @tuanbuilab.bsky.social · 30/01/2025
More compelling evidence that axoaxonal GABA release in the spinal cord can increase sensory transmission. Cell Reports www.cell.com/cell-reports...
cell.com
Pharmacological blocking of spinal GABAA receptors in monkeys reduces sensory transmission to the spinal cord, thalamus, and cortex
Mahrous et al. examine the controversial role of GABAARs in sensory transmission in the monkey cervical spinal cord. They find that blocking spinal GABAARs reduces sensory input to both motoneurons an...
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Tuan Bui @tuanbuilab.bsky.social · 29/01/2025
Wishing everyone a Happy Tet! Lots of good health and prosperity for the new year
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Tuan Bui @tuanbuilab.bsky.social · 03/01/2025
Preprint from the lab (a bit late in announcing). First-year graduate student, Shahriar Nasiri, with a detailed optogenetic mapping of dI3 neuron circuitry within and between cervical and lumbar spinal cord www.biorxiv.org/content/10.1...
biorxiv.org
Mapping of dI3 neuron sensorimotor circuits across the cervical and lumbar spinal cord
From the fine control of hand movements to the dynamic corrective adjustments during locomotion, spinal circuits integrate descending supraspinal and sensory inputs to modulate diverse motor functions...
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Tuan Bui @tuanbuilab.bsky.social · 12/12/2024
Chuffed to bits about my visit to the Manitoba Neuroscience Network today. Can't wait to see old friends and make new ones, and to catch up on all the excellent neuroscience happening at the University of Manitoba. Will also have a word about them joining Blue Sky!
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Tuan Bui @tuanbuilab.bsky.social · 29/11/2024
Preprint about the development of the M-current in primary motoneurons in zebrafish. Great work by PhD student, Stéphanie Gaudreau, and she's already gotten some more data to go along with this story but an updated version to come sometime in Winter 2025 www.biorxiv.org/content/10.1...
biorxiv.org
Developmental changes in the control of primary motoneuron excitability by the M-current in larval zebrafish
Spinal circuits for locomotion undergo maturation during early development. How intrinsic properties of individual spinal neuron populations change throughout motor maturation is not fully understood....
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Tuan Bui @tuanbuilab.bsky.social · 21/11/2024
Our department (BIO, University of Ottawa) is hiring for a Canadian Research Chair Tier 2 position in Multicellular Systems and Modelling with a focus on mechanisms of brain and cardiovascular systems Please send me a DM for more info! www.nature.com/naturecareer...
nature.com
Job Search | Nature Careers
Jobs in Ottawa. 1 job to view and apply for now with Nature Careers | by Distance
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Tuan Bui @tuanbuilab.bsky.social · 16/11/2024
I did not realize how liberating it would feel to move to Blue Sky
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