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Tobias Lenz

@biotobi.bsky.social
865 followers 165 following 52 posts

Professor of Evolutionary Immunogenomics @uni-hamburg.de Evolutionary Genetics, Eco-Immunology, Host-Parasite Coevolution, Evolutionary Medicine, MHC/HLA. Only research-related posts. www.biologie.uni-hamburg.de/evoluti…

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Tobias Lenz @biotobi.bsky.social · 25/08/2026
Very interesting paper on variation in promiscuity of #HLA allotypes and its role for immunity, also looking at UKBiobank data | by @matemanc.bsky.social and colleagues | Thanks to @jcwinternitz.bsky.social for sharing www.nature.com/articles/s41...
nature.com
HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections - Nature Communications
Human leukocyte antigen class II (HLA-II) are involved in the presentation of peptides to helper T cells which guide in the B cell response and antibody production. Here Magyari et al, show that HLA-I...
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Jamie Winternitz @jcwinternitz.bsky.social · 14/10/2025
Despite frequent inbreeding, banded #mongooses show #MHC diversity on par with species of least conservation concern. New📄Schubert et al. 2025 #BMCEcolEvol provide first full MHC characterization in a wild social #carnivore @bmc.springernature.com #conservationgenetics 👉 doi.org/10.1186/s128...
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Tobias Lenz @biotobi.bsky.social · 21/07/2026
Interesting paper on #TCR repertoire variation in wild-caught mice. While not controlled for genetics or exposure history, it gives important insights into the extent of variation in a natural setting. academic.oup.com/discovimmuno...
academic.oup.com
The T-cell receptor repertoire of wild mice
AbstractIntroduction. Wild animals live in a pathogen-rich environment and are normally infected with a wide range of micro- and macro-parasites. Wild anim
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Paul Rainey @paulbrainey.bsky.social · 13/07/2026
My postdoc director called my work "phenomenological" and forbade it. I walked to a museum, found Tinbergen had shared a Nobel for work of exactly that kind, and finished the study anyway. On temperament, luck, and what the system selects against 👇 academicrenewal.substack.com/p/a-certain-...
open.substack.com
A certain cast of mind
The argument about research culture leaves out something personal, and no reform reaches it.
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Paul Rainey @paulbrainey.bsky.social · 01/06/2026
Pleased to see this beautiful paper out. Kudos to @jeroenmeijer.bsky.social who took @stevenquistad.bsky.social data and dug deep, revealing a new phage that erupts to astonishing abundance. As theory predicts, the life of SGEs is fuelled by encounters with new hosts www.science.org/doi/10.1126/...
science.org
Eco-evolutionary dynamics of massive, parallel bacteriophage outbreaks in compost communities
A single bacteriophage can dominate microbial communities yet only evolves when migration changes its ecological context.
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Antigen Evolution & Design Lab @antigenevo.bsky.social · 07/07/2026
Inaugural post! We are a brand new lab @pasteur.fr studying how pathogen antigens evolve and how we can exploit these proteins' evolution to make better vaccines! Read a few words from the currently sole member of the lab @spyroslytras.bsky.social below! 😁 www.pasteur.fr/en/research-...
pasteur.fr
Predicting viral evolution with AI
Spyros Lytras is one of four young scientists selected in 2025 to lead new research groups at the Institut Pasteur. He has headed the “Antigen Evolution & Design laboratory” 5-year Group (G5) since Ju...
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Diyar H. (He/Him) @diyarhamidi.bsky.social · 06/07/2026
Great experience at #SMBE26 @official-smbe.bsky.social in Copenhagen, where I shared my research on the evolution of HLA diversity in a Native American population. Many thanks to the Ancient and Historical Genomics Symposium and my supervisor @biotobi.bsky.social!
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Molecular Biology and Evolution @molbioevol.bsky.social · 01/07/2026
Behind every paper in MBE, there's this - a group of excellent and dedicated scientists, serving the SMBE community on our editorial board. By committing their time, these editors make the society's mission to support and connect molecular evolutionists possible. #societyjournal #society #SMBE2026
SMBE 2026 | MBE Editorial Board
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Roli Roberts @roliroberts.bsky.social · 02/07/2026
Researchers in #EvolutionaryBiology & #Ecology wanting to do the right thing? @nicolasgaltier.bsky.social at #SMBE2026 talking about DAFNEE, a database of >600 #ecoevo #evoeco academia-friendly journals for "responsible publishing" - @plos.org seems to do OK here...!
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 02/07/2026
Save the date for the 2027 SMBE Conference in Québec City! The LOC of #SMBE2027 would like to welcome you to Québec City for the 2027 Conference of the Society for Molecular Biology and Evolution,from June 20-24, 2027, and hosted by Université Laval at the Québec Convention Centre. #society
Save the Date
SMBE2027
Québec City, Canada
June 20-24, 2027
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Joanna Malukiewicz @arcova.bsky.social · 29/06/2026
Had a blast discussing primate immunogenetics at #VPG WORKSHOP: Future Directions in Vertebrate Genomics Research at #SMBE at Copenhagen. I also discussed what my Prima: Primates, Immunogenetics, and Adaptation research group will be up to at the University of São Paulo #USP
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Joanna Malukiewicz @arcova.bsky.social · 02/07/2026
@acstone.bsky.social getting 2026 #SMBE life time contribution award 😍😍😍🥳🥳🥳🎉🎉🎉🍾🍾🥂🥂🥂 congrats Anne !!!
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Genetics Society UK @gensocuk.bsky.social · 26/06/2026
Congratulations to Prof Richard Durbin, winner of the 2026 Genetics Society Medal! His pioneering work in computational genomics has transformed how we analyse and understand genome sequences.
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Tobias Lenz @biotobi.bsky.social · 01/07/2026
Happy to see @arcova.bsky.social from the lab presenting latest results from her study system of Marmosets and Yellow Fever at #SMBE2026
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Tobias Lenz @biotobi.bsky.social · 01/07/2026
Very proud to see my PhD student @diyarhamidi.bsky.social present at #SMBE2026 about selection on #HLA genes in Native Americans in the context of exposure to novel pathogens due to the invasion by Europeans.
Diyar presenting on the main stage
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Tobias Lenz @biotobi.bsky.social · 16/06/2026
SIP2026 - Where #evolution, #genetics, and #immunology meets! Abstract and early bird deadlines have been extended to June 29! Ever wanted to chat in an informal setting with one (or more) of the folks shown below? Then this is your chance: sip-sassenheim.org Join us in the Netherlands, Nov 2-4
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Tobias Lenz @biotobi.bsky.social · 06/06/2026
Please share: Abstract deadline approaching (June 15) for the 2026 Annual Symposium of the Society for Immune Polymorphism (Nov 2-4, Netherlands). Intimate community meeting on variation and evolution of immunity and immune genes. Exciting lineup of invited speakers. #MHC #HLA sip-sassenheim.org
SIP2026 poster with invited speakers
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EvolDir @evoldir.bsky.social · 21/04/2026
📣 EvolDir is now managed by @eseb.bsky.social! We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now 👏 You can now find evoldir here: evoldir.net
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Jacek Radwan @jacek-radwan.bsky.social · 25/03/2026
Interested in evolutionary immunogenetics? This is an excellent, small conference bringing together hardcore immunologists and eco-evo people sip-sassenheim.org
sip-sassenheim.org
SIP Symposium |
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Diyar H. (He/Him) @diyarhamidi.bsky.social · 21/04/2026
Short time ago, we, the Evolutionary Immunogenomics Research Group, organized the 29th DZG Graduate Meeting in Evolutionary Biology @dzg-evol.bsky.social at the IZS, University of Hamburg @uni-hamburg.de, bringing together early-career researchers for inspiring talks, discussions, and networking.
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Eric Topol @erictopol.bsky.social · 16/04/2026
Eradicating tumors with a mRNA vaccine in the experimental model www.pnas.org/doi/10.1073/...
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Ishmail Abdus-Saboor @ishmailsaboor.bsky.social · 17/04/2026
This program transformed my career! Please apply. @hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits. Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA
bit.ly
Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI
The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...
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Nels Elde @elearlybird.bsky.social · 17/04/2026
Biologists Confirm Not Much Evolution Happened Today — theonion.com/biologists-c...
theonion.com
Biologists Confirm Not Much Evolution Happened Today
STANFORD, CA—Calling it a “pretty slow one” as far as natural selection and genetic drift were concerned, biologists from Stanford University confirmed Tuesday that not much evolution happened today. ...
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Tobias Lenz @biotobi.bsky.social · 23/02/2026
We are extending the deadline to Feb 27, since we still have a few slots. 👉 A semi-informal event to interact with your peers, learn about cutting-edge research, and hear from two leaders in the field (Sophie Armitage & Dieter Ebert). And it's free! 🎉 PIs, please recommend to your grad students!
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Tobias Lenz @biotobi.bsky.social · 17/02/2026
Just a quick reminder that the abstract deadline is approaching for the DZG Graduate Meeting in Evolutionary Biology 2026: Feb 20! 👈 We still have a few places left 🤗🌈
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Irene Gallego Romero @ee-reh-neh.bsky.social · 16/02/2026
Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share. Tldr: scRNA-seq in Indonesia hard but fun
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EFIS_Immunology @efis-immunology.bsky.social · 13/02/2026
📢2nd Annual Meeting of the EFIS-IL Sex Differences in Immunity Study Group! 🗓️October 8-9, 2026 📍Hamburg, Germany 🔗https://linktr.ee/EFIS_ISD @yefis-immunology.bsky.social @dgfi-org.bsky.social @sfi-immunologie.bsky.social @swimm-immuno.bsky.social @irishimmunology.bsky.social @finnsocimm.bsky.social
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Adrian Liston @labliston.bsky.social · 16/02/2026
Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field www.annualreviews.org/content/jour...
annualreviews.org
Tissue Regulatory T Cells
FOXP3+ regulatory T cells (Tregs) have well-defined roles in limiting systemic immune responses against diverse stimuli. However, the observation that a subset of Tregs also enter nonlymphoid tissues,...
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Ele Willoughby @minouette.bsky.social · 15/02/2026
#BlackHistoryMonth is a great time to celebrate #biochemist Marie Maynard Daly (1921-2003), 1st Black woman to earn a PhD in #chemistry in the US! 🧪🐡👩🏿‍🔬 #histsci She made important research contributions to our understanding of the biochemisty of the cell nucleus & cardiovascular issues & the 🧵
My linocut portrait of Marie Maynard Daly in purples (she’s a young smiling Black woman, wearing earrings, a necklace and a dress, looking at the viewer over her shoulder). Above her to the right is an anatomical heart with a blowout diagram in a circle of a clogged artery and the cholesterol molecule all in red. Next to her on the left in blue are the molecules of the bases which make up DNA and a diagram of a human cell.
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Mark A. Hanson @hansonmark.bsky.social · 30/01/2026
To argue "infections" are an extrinsic factor to heritability is bizarre to me - as if aging takes place in a vacuum. Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects). I don't disagree longevity is highly heritable... 1/2
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Emmanuel Saliba @emmanuel-saliba.bsky.social · 28/01/2026
🔔HIRI has opened a new call to recruit Group Leaders. If you are interested in opening an RNA Biology and Infection lab, join us! Deadline: February 15. More info here 👇
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Tobias Lenz @biotobi.bsky.social · 27/01/2026
Deadline for #SMBE2026 abstract submission is coming up (Feb 3)! Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
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Oded Rechavi @odedrechavi.bsky.social · 16/01/2026
Tha'ts what scientists want too. We need AI that makes sure you don't break the dishes (or centrifuge)
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Tobias Lenz @biotobi.bsky.social · 13/01/2026
Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
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Adam Phillippy @aphillippy.bsky.social · 12/05/2025
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
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EMBL @embl.org · 11/09/2025
Establish your own independent research group as Group Leader - AI in Biology. We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
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Miranda Shafer @mirandashafer.bsky.social · 11/09/2025
“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
pod.link
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Society for the Study of Evolution @sse-evolution.bsky.social · 11/09/2025
Applications due Monday September 15 for the International Event Grants! These grants support symposia, workshops, courses, and other evolutionary biology events, including virtual events. Learn more and apply now: rb.gy/76fgi
Text: Society for the Study of Evolution International Event Grants. Applications due September 15.
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Nicola Rennie @nrennie.bsky.social · 11/09/2025
I've written a short blog post introducing "The Art of Visualization with ggplot2"! This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots! nrennie.rbind.io/blog/art-of-... #RStats #DataViz #TidyTuesday
nrennie.rbind.io
Introducing The Art of Visualization with ggplot2 – Nicola Rennie
I’ve written a book! This blog post gives a brief introduction to The Art of Visualization with ggplot2, a book of data visualization case studies showing the end-to-end process of building charts, st...
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The American Journal of Human Genetics @ajhgnews.bsky.social · 10/07/2025
📣New today! 📄Haplotype analysis reveals pleiotropic disease associations in the HLA region 🧑‍🤝‍🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
cell.com
Haplotype analysis reveals pleiotropic disease associations in the HLA region
The HLA region plays an important role in human health but is often excluded in large-scale GWASs. We performed haplotype-based associations from genotype data to investigate pleiotropy across thousan...
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Fillip Port @crisprflydesign.bsky.social · 12/07/2025
Some PIs will stop at nothing to motivate their lab members. 🧪
Graffiti at the end of an underpass in Heidelberg saying 'LAB!'.
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Tobias Lenz @biotobi.bsky.social · 11/07/2025
Join the annual meeting of the Society for Immune Polymorphism (SIP), November 3-5, Netherlands! A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species. Early bird/Abstract deadline is Aug 15: sip-sassenheim.org
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Young Belgian Immunological Society @ybis.bsky.social · 11/04/2025
📣 2 #Immunology #Summer_Schools that might be of interest to you: If you are working on adaptive immune receptor repertoire: ut.ee/en/content/c... If you want to get deeper into new advances in Immunology: focis2025.univ-rouen.fr/page.php?pag... #ImmunoSky
ut.ee
Computational Immunology Summer School
Join the Computational Immunology Summer School to explore the fascinating world of Adaptive Immune Receptor Repertoires (AIRRs), mastering cutting-edge bioinformatics tools and lab techniques to uncover the secrets of immune system diversity.
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Thiago Carvalho @cyrilpedia.bsky.social · 11/04/2025
'Compared with the patients’ doctors, the AI model more often failed to detect the presence of disease in Black patients or women, as well in those 40yrs or younger. Wn the researchers looked at race and sex combined, Black women fell to the bottom, with the AI not detecting disease in half of them'
science.org
AI models miss disease in Black and female patients
Analysis of chest x-rays underscores need for monitoring artificial intelligence tools for bias, experts say
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Constantin Pape @cppape.bsky.social · 11/04/2025
Interested in starting your research group in AI and applications to science? Check out our upcoming online event for DFG funded opportunities in Goettingen!
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ESEB 2025 Congress @eseb2025.bsky.social · 09/04/2025
Your research matters! Contribute to the future of #EvolutionaryBiology by submitting your Abstract to #ESEB2025. 🔬 Explore over 50 topics, including: ✅ #Evolution in all its aspects ✅ #Genetics & #Genomics ✅ New Frontiers and more! 📩 Submit now: eseb2025.com/call-for-abs...
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Joanna Malukiewicz @arcova.bsky.social · 09/04/2025
📢 new paper alert for the primate and genomics nerds. telomere to telomere ape genomes. I led MHC annotations on this work w/ @biotobi.bsky.social and @meyerbritta.bsky.social And hey it’s my first nature paper 🥳 www.nature.com/articles/s41...
nature.com
Complete sequencing of ape genomes - Nature
Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...
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Warwick Anderson @wombatscholar.bsky.social · 08/04/2025
Medicine on a Larger Scale: Global Histories of Social Medicine, eds @ahlie.bsky.social, Jeremy Greene, and me, will be available open access from @cambridgeup.bsky.social in May 2025. In a world of growing health inequity, radical social medicine has never been more urgent! #histstm #histmed #sts
cambridge.org
Medicine on a Larger Scale
Cambridge Core - History of Medicine - Medicine on a Larger Scale
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Kayla King, Ph.D. @kayla-king.bsky.social · 31/03/2025
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
zoology.ubc.ca
Join Us! | King Lab
Are you interested in joining the King Lab? More information here!
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