Very interesting paper on variation in promiscuity of #HLA allotypes and its role for immunity, also looking at UKBiobank data | by @matemanc.bsky.social and colleagues | Thanks to @jcwinternitz.bsky.social for sharing www.nature.com/articles/s41...
nature.com
HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections - Nature Communications
Human leukocyte antigen class II (HLA-II) are involved in the presentation of peptides to helper T cells which guide in the B cell response and antibody production. Here Magyari et al, show that HLA-I...