Identification of genetic variants associated with the efficacy and side effects of GLP1 medications could underpin development of precision medicine approaches in the treatment of obesity.

A programme that offers scans to smokers between the ages of 55 and 74 detects a large number of early-stage lung tumours.

The winning paper presents a software tool for quickly and accurately identifying which species’ DNA are present in a sample.

Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For

A very impressive body of evidence has accumulated

In machine learning (ML), a widespread claim is that the area under the precision-recall curve (AUPRC) is a superior metric for model comparison to the area under the receiver operating characteristic...

Differential isoform usage is identified with high statistical power from spatial transcriptomics data.

Lung adenocarcinomas bearing the ID2 mutational signature display increased LINE-1 retrotransposon activity, which contributes to their fast evolutionary dynamics and aggressive phenotype.

This randomized clinical trial examines whether risk-based screening is a safe and effective alternative to annual mammography for detecting breast cancer in women 40 years and older.

As biotech firms shed jobs and life sciences funding dries up, policymakers have started to see defense technology as a way to buttress the Massachusetts economy. Industry experts say Cambridge may be...

JASPAR is the largest open-access database of curated and non-redundant transcription factor (TF) binding profiles from six different taxonomic groups.

A collection of high-quality human genomes. Contribute to lh3/human-asm development by creating an account on GitHub.

Abbott Laboratories is nearing a potential acquisition of medical-testing company Exact Sciences Corp., in what would be its largest deal in nearly a decade, people familiar with the matter said.

WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...

Consumer Reports expressed concern about high levels of lead in some two dozen protein powders, but only with repeated high exposure. Here's what to know before you make your next grocery run.

Tahchin is a Persian rice dish in which the rice is mixed with yogurt, oil, egg yolks and saffron and baked until a golden crust forms at the bottom (Persians refer to this as the tahdig) The rice on the inside becomes buttery and almost cake-like and is often layered with chicken and barberries, a tart dried fruit that has a beautiful crimson color This version incorporates common Thanksgiving ingredients like rosemary, sweet-tart cranberries and buttery onions to make a striking dish that feels more like a main than a side

Predicting disease risk from DNA presents an unprecedented emerging challenge as biobanks approach population scale sizes (N>106 individuals) with ultra-high-dimensional features (L>105 genotypes). Cu...