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George Ghanim

@automnenine.bsky.social
561 followers 353 following 68 posts

Assistant Professor @ Princeton MolBio | From transposons to telomeres and back | bicycles and biochemistry ghanim.lab.princeton.edu

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Reposted by George Ghanim
Science Magazine @science.org · 27/08/2026
On the citizen science platform Eterna, #AI methods matched expert human players at inventing sequences that fold into an RNA pseudoknot, a structure in which loops pair with distant parts of the same molecule. Learn more this week in Science: scim.ag/4wOqvuE
Each diagram is a designed RNA pseudoknot, a structure in which loops pair with distant parts of the same molecule. On the citizen science platform Eterna, artificial intelligence methods matched expert human players at inventing sequences that fold into these shapes, opening a route to automatically designing RNA therapeutics, sensors, and catalysts from scratch.

Image: J. Townley et al., Science 393 , 931 (2026); Adapted by N. Jessup/Science
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George Ghanim @automnenine.bsky.social · 18/08/2026
The Department of Molecular Biology at Princeton is recruiting at the Assistant Professor level. This is a wonderful environment to start a lab and do research. Come be our colleague! See the link for more details: apply.interfolio.com/190686
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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George Ghanim @automnenine.bsky.social · 13/08/2026
Keeping this dream alive. Hot off the typhoon.
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George Ghanim @automnenine.bsky.social · 11/08/2026
Right! This is neat.
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Reposted by George Ghanim
Da-Neng Wang @danengw.bsky.social · 28/07/2026
Congratulations to Chris Russo, MRC Laboratory of Molecular Biology, for receiving the 2026 K.H. Kuo Award for Distinguished Scientist in Biological Electron Microscopy www.bsc.org.cn/KuoSymposium...
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Da-Neng Wang @danengw.bsky.social · 28/07/2026
Congratulations to Ellen Zhong, Princeton University, for receiving the 2026 K.H. Kuo Award for Outstanding Young Scientist in Structural Biology www.bsc.org.cn/KuoSymposium...
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George Ghanim @automnenine.bsky.social · 24/07/2026
😦 This is wizardry!
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Cedric Feschotte @cedricfeschotte.bsky.social · 13/07/2026
📣 Abstract submission deadline for CSHL TEs extended to July 24! Two more weeks to submit your abstract for a short talk or poster — do it! It’s gonna be a fantastic meeting!! meetings.cshl.edu/meetings.asp...
meetings.cshl.edu
Transposable Elements
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
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Reposted by George Ghanim
Matthew Taliaferro @jmtali.bsky.social · 11/06/2026
New paper! How do RNAs "know" where to go inside a cell? We dug into the sequence elements that route RNAs to the right place. It turns out that, in mammals, they're surprisingly massive (>200 nt), multipartite, and wonderfully complicated. 🧵
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Cedric Feschotte @cedricfeschotte.bsky.social · 29/05/2026
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com
thefeschottelabatcornell.com
The Feschotte Lab at Cornell
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Princeton MolBio @princetonmolbio.bsky.social · 15/05/2026
Little is known about how the immune system responds to pregnancy and lactation and why and how these changes take place. New research from the lab of Ai Ing Lim details extraordinary changes in mothers’ immune systems to ensure successful reproduction. molbio.princeton.edu/news/2026/li...
molbio.princeton.edu
Lim Lab: Mothers’ secret recipe for fending off infection
Surprisingly little is known about how the immune system responds to pregnancy and lactation, and why and how these changes take place. This research details extraordinary changes that take place in m...
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George Ghanim @automnenine.bsky.social · 01/05/2026
Happy May Day everyone!
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George Ghanim @automnenine.bsky.social · 28/04/2026
That cliffhanger...
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Reposted by George Ghanim
cryoEM papers @cryoempapers.bsky.social · 22/04/2026
The vault associates with membranes in situ pubmed.ncbi.nlm.nih.gov/42014721/ #cryoEM
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George Ghanim @automnenine.bsky.social · 04/04/2026
It happened so fast...
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Reposted by George Ghanim
Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 17/03/2026
AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk
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George Ghanim @automnenine.bsky.social · 13/03/2026
I’ve always wondered what a compustage was. Neaat.
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Reposted by George Ghanim
Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 06/03/2026
The Protein Data Bank (#PDB) has reached a new milestone: 250,441 entries in the archive, a record since its founding in 1971, all thanks to the efforts and contributions of the structural biology community. ⬇️ more ⬇️ www.wwpdb.org/news/news?ye... #StructuralBiology
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Kai Mesa @kaimesa.bsky.social · 06/02/2026
Looking for motivated postdocs interested in doing exciting research at the intersection of immunology and regenerative biology. We use intravital two-photon imaging to track and manipulate immune cell behavior at the single-cell level in live animals mesa-lab.org Apply: apply.interfolio.com/180660
mesa-lab.org
Mesa Laboratory
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George Ghanim @automnenine.bsky.social · 21/01/2026
🎊🎉🥳
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Reposted by George Ghanim
Di Jiang @dijiang319.bsky.social · 15/01/2026
🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org
science.org
A genetically encoded device for transcriptome storage in mammalian cells
Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...
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Reposted by George Ghanim
Manny Ares 👀 @mannyares.bsky.social · 02/01/2026
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George Ghanim @automnenine.bsky.social · 18/12/2025
Someone was asking about doughnuts the other day.
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George Ghanim @automnenine.bsky.social · 09/12/2025
🥳🥳🎉🥳
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Ädam Ligeralde @aktaguy.bsky.social · 03/12/2025
Calling all structural biologists in the NYC metro area! The nysbdg.bsky.social is back for yet another gathering for 2025! Register here 👉🏼 buff.ly/N42ul1b I look forward to seeing you there! 😎 #structuralbiology #cyrstallography #cryoEM #NMR #chromatography #proteinpurification #AKTAsystems
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Reposted by George Ghanim
Alan Brown @alanbrownhms.bsky.social · 18/11/2025
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
academicpositions.harvard.edu
HMS - Postdoctoral Fellow in BCMP, Brown Lab
We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...
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Reposted by George Ghanim
Sonya @sonyahanson.bsky.social · 07/11/2025
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
heterogeneity.notion.site
CAHRA 2025: Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms
A community-wide data processing challenge for cryo-electron microscopy.
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George Ghanim @automnenine.bsky.social · 23/10/2025
#CryoEM how do we feel about this instrument? We may be in the market and I want to know what people are currently using.
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George Ghanim @automnenine.bsky.social · 18/10/2025
Hummm
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George Ghanim @automnenine.bsky.social · 16/10/2025
This is an auto include on my reading list because I know its going to be good. Congrats @vcushing.bsky.social @bjgreber.bsky.social and all!
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Reposted by George Ghanim
Kai Mesa @kaimesa.bsky.social · 15/10/2025
When Macrophages Disappear, Skin Blood Vessels Age! Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology 👇👇 www.nature.com/articles/s41...
nature.com
Niche-specific dermal macrophage loss promotes skin capillary ageing - Nature
Capillary-associated macrophages are selectively lost over time, contributing to impaired vascular repair and reduced tissue perfusion in older mice.
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Lori Passmore @lapassmore.bsky.social · 27/09/2025
We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM. Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩 #RNA #cryoEM
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Reposted by George Ghanim
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 25/09/2025
Congrats to #LMBAlumni Juan B. Rodriguez Molina, former Investigator Scientist in the LMB's Structural Studies Division, newly appointed Assistant Professor in the Dept of Molecular and Cellular Biosciences at the University of Cincinnati College of Medicine researchdirectory.uc.edu/p/1818215
Juan B. Rodriguez Molina
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Dimitry Tegunov @dtegunov.bsky.social · 13/09/2025
Important to remember the theoretical size limit is based on assumptions and a model that may or may not be complete. It isn't some indisputable universal truth.
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George Ghanim @automnenine.bsky.social · 02/09/2025
Hey thats me.
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Reposted by George Ghanim
Martin Pacesa @martinpacesa.bsky.social · 27/08/2025
Since when are vaults cool again? Loving it
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Cameron Myhrvold @cambearon.bsky.social · 15/08/2025
My lab has developed mSHINE, allowing for both highly multiplexed and portable nucleic acid detection. Very exciting work led by the talented @sijbren-kramer.bsky.social, who is off to do a PhD at Stanford at the end of the month!
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Reposted by George Ghanim
AJ te Velthuis @ajtevelthuis.bsky.social · 08/08/2025
Now out in Science Advances: www.science.org/doi/10.1126/...
science.org
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George Ghanim @automnenine.bsky.social · 07/08/2025
😍😍😍
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Carter Lab @carter-lab.bsky.social · 05/08/2025
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. www.biorxiv.org/content/10.1...
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 04/08/2025
The LMB recently hosted a symposium to mark 50 years since Richard Henderson and Nigel Unwin published the structure of bacteriorhodopsin, the first 3D structure of a protein determined by #cryoEM. Read about the event and find more photos here: www2.mrc-lmb.cam.ac.uk/the-structur... #LMBNews 🧪🔬
Attendees of the recent bacteriorhopsin symposium, photographed from above.Balsawood model of bacteriorhodopsinBlack and white photograph of Nigel Unwin and Richard Henderson sitting outside the LMB, 1991Symposium attendees applauding in the LMB's Max Perutz Lecture Theatre.
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Coleen Murphy @ctmurphy1.bsky.social · 30/07/2025
I somehow missed this piece about Jon in my lab: molbio.princeton.edu/news/2025/jo...
molbio.princeton.edu
Jonathan St. Ange Receives Fulbright U.S. Student Award for 2025-2026
Jonathan St. Ange, a Ph.D. Student in Molecular Biology at Princeton University, has received a Fulbright U.S. Student Program award to conduct research in Molecular Biology in France for the 2025-202...
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George Ghanim @automnenine.bsky.social · 18/07/2025
I just got it. This is great.
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Gael Cristofari @retrogenomics.bsky.social · 11/07/2025
🦟 Bioinformatics Research Scientist position open in my lab in Nice (FR) to study Aedes mosquito retrotransposons & their interactions with arboviruses collab w/ @salehlabparis.bsky.social & @lambrechtslab.bsky.social Apply: euraxess.ec.europa.eu/jobs/359830 Please boost! #ArboRetro #Bioinformatics
Aedes albopictus (asian tiger mosquito)
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John Rubinstein @johnrubinstein.bsky.social · 12/07/2025
Returned from a wonderful symposium in honour of the 50th anniversary of Richard Henderson's and Nigel Unwin's 1975 paper on the structure of bacteriorhodopsin - the paper that started the field of membrane protein structural biology. Also fulfilled my dream of ringing the LMB seminar bell.
At Darwin College:
Richard Henderson
Jacqueline Milne
Sriram Subramanian
Nigel Unwin
David Barford
Da-neng Wang
John RubinsteinJohn ring's the LMB seminar bell to call the audience back in after a coffee break.
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Kelly Nguyen @kellythd-nguyen.bsky.social · 11/07/2025
Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.
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George Ghanim @automnenine.bsky.social · 08/07/2025
Hurray! 🥳🎉🥂
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Basil Greber @bjgreber.bsky.social · 27/06/2025
Goodbye Nucleic Acids GRC, goodbye Tuscany - this was great! Thanks to Jane Jackman and Brandt Eichman for organising this fantastic conference!
The town of Barga in Italy illuminated by the evening sun.
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