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Anna Poetsch

@apoetsch.bsky.social
2.4K followers 308 following 108 posts

Computational Biologist at Uni Köln. Interested in how genomes encode their own stability.

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Reposted by Anna Poetsch
Cologne Graduate School of Ageing Research @cga-age.bsky.social · 26/08/2026
Do you want to start your PhD at the Cologne Graduate School of Ageing Research in 2027? 🗓️ Don't miss our deadline: November 3, 2026. To help you get started with your application, our wonderful PhD students and faculty members have some tips for you in our short video. Enjoy! 🍿
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MPI for Biology of Ageing @mpiage.bsky.social · 25/08/2026
🚀 Applications now open for the CECAD Postdoc Academy for Aging Trajectories! We are thrilled to share the first call for applications for our new CECAD Postdoc Academy for Aging Trajectories. www.cecad.uni-koeln.de/career/postd...
cecad.uni-koeln.de
CECAD: Postdoc Academy
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Andreas Beyer Group @beyerlab.bsky.social · 24/08/2026
Apply now! This is a great opportunity for truly interdisciplinary research.
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ETH Laboratory of Toxicology @sturlalab.bsky.social · 21/08/2026
Check out the STAR publication: "Click-code-seq protocol for genome-wide single-nucleotide-resolution mapping of major types of DNA modifications" ⭐ www.cell.com/star-protoco... 🧬 Whole #genome instability 💻 #Computational pipeline
cell.com
Click-code-seq protocol for genome-wide single-nucleotide-resolution mapping of major types of DNA modifications
DNA modifications are central to carcinogenesis, chemotherapy drug action, neurodegeneration, and aging. Here, we present a protocol for click-code-seq, a next-generation sequencing technique for geno...
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CRC1678 @crc1678.bsky.social · 20/08/2026
🚨 Publication Alert 🚨 New study from #CRC1678 members @beyerlab.bsky.social and @muellerrom.bsky.social maps kidney and liver disease using cell‑type‑specific damage scores. PDS/HDS track cell injury and reveal circadian disruption and a MASLD/NASH threshold. 🍾🥳 👉 www.cell.com/cell-genomic...
cell.com
Cell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomics
Padvitski, Unger Avila, Chen et al. introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury,...
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Reposted by Anna Poetsch
Cologne Graduate School of Ageing Research @cga-age.bsky.social · 11/08/2026
🚀 Apply now for 12 fully funded PhD positions at the Cologne Graduate School of Ageing Research! Join us and start your PhD in an international community at the forefront of ageing research. 🧬🔬 🗓️ Deadline: November 3, 2026 Explore the projects & apply: www.ageing-grad-school.de 📣 Spread the word!
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Anna Poetsch @apoetsch.bsky.social · 03/08/2026
We are happy to present a new paper on gene regulation on the way to regenerating the spinal cord www.biorxiv.org/content/10.6... 🧵 1/4
biorxiv.org
Baseline regulatory programs in larval and adult neural progenitors converge towards an injury-induced state after spinal cord injury
Regeneration after spinal cord injury requires progenitor cells to convert injury-associated signals into coordinated remodeling of gene regulatory programs. Mammalian spinal progenitors show limited ...
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Anna Poetsch @apoetsch.bsky.social · 03/08/2026
We are happy to present a new paper on the sequence dependence of 🧬 replication timing in the cell cycle. www.biorxiv.org/content/10.6... 🧵 1/6
biorxiv.org
Using Deep Learning to predict replication timing reveals baseline control of genomic DNA sequence
Human DNA replicates according to a precise schedule: certain regions are replicated early, while others replicate later in the cell cycle. The DNA sequence and the epigenome are both indicative for r...
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Anna Poetsch @apoetsch.bsky.social · 18/05/2026
We are looking for a Data and IT manager. You would set up the group’s data infrastructure, data flows, and overall organization on HPC. We aim to understand genomes 🧬 and ageing 👵 with Big Data and Machine / Deep Learning. Interested? Please apply through jobportal.uni-koeln.de/ausschreibun...
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Universität zu Köln @unicologne.bsky.social · 15/05/2026
🎉Zwei Sonderforschungsbereiche an der Universität zu Köln werden verlängert 🌱🧬Der Sonderforschungsbereich (SFB) 1530 „Aufklärung und Targeting pathogener Mechanismen bei B-Zell-Neoplasien“ und der SFB/TRR 341 „Ökologische Genetik der Pflanzen“ gehen in die zweite Förderperiode ▶️ uni.koeln/J5KLR
Bronzestatue einer sitzenden Person mit Buch vor einem modernen Gebäude mit großen Glasfenstern.
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Anna Poetsch @apoetsch.bsky.social · 11/05/2026
A bit more than a week to apply 🧬💻 Also stay tuned for more adds, there will be one for a single cell multiomics postdoc 🧫and one for a Data & IT manager 📈
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Anna Poetsch @apoetsch.bsky.social · 08/05/2026
Our field has lost a giant. I will never forget his talk I heard as a master student in Tokyo. It was very inspiring for someone so young. However, I am not sure how much the rest of the audience benefited - the French accent was superb, too 🇫🇷 Anyway, I asked the only question 🤭
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The EMBO Journal @embojournal.org · 07/05/2026
SLX4IP acts as a genome-wide brake on BLM helicase activity to preserve replication fork stability under stress – both globally and at ALT telomeres Stephanie Panier @spanier55.bsky.social, Kavi Mehta @k4v1.bsky.social and coworkers link.springer.com/article/10.1...
link.springer.com
SLX4IP limits replication stress globally and at ALT telomeres - The EMBO Journal
Faithful DNA replication is essential for genome stability, yet replication forks face constant stress. The Bloom syndrome helicase (BLM) safeguards fork integrity, but excessive BLM activity can itse...
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Björn Schumacher @bjornschumacher.bsky.social · 25/04/2026
Connecting fragmented aging research through the European Federation for Aging Research | Nature Aging. Read here how EFAR will provide a new platform for the geroscience community ⁦‪Morten Scheibye-Knudsen ‬⁩, Lene Rasmussen, Folkert Kuipers www.nature.com/articles/s43...
nature.com
Connecting fragmented aging research through the European Federation for Aging Research - Nature Aging
Nature Aging - Connecting fragmented aging research through the European Federation for Aging Research
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Anna Poetsch @apoetsch.bsky.social · 01/05/2026
Are you looking for a new challenge? We are looking for a Deep Learning Engineer. With this role you would set up deep learning infrastructures with the goal to understand genomes 🧬 and ageing 👵 .
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Anna Poetsch @apoetsch.bsky.social · 08/04/2026
Medical data protection is important and I do understand that the German laws for doing research with them are rather strict. But why is it allowed that private health insurances insist on you signing to lift all restrictions and allow them to store everything forever?
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Anna Poetsch @apoetsch.bsky.social · 31/03/2026
I am delighted, humbled, proud, and grateful to let you know that I became a professor for life today. I am very aware of the privilege that this position now brings to my life. I will do my best to pay forward the kindness and support of the people who got me here.
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Anna Poetsch @apoetsch.bsky.social · 14/03/2026
I love this initiative. I think generally it would be great to have a grant system for providing basic income, if private citizens propose something that enriches society. This could be art, literature, building up something. It may even make sense for doing science or humanities.
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CRC1678 @crc1678.bsky.social · 02/03/2026
🚨 Speaker Alert! 🚨 We’re excited to welcome Dr. Anna Poetsch to our upcoming #CRC1678 Seminar 🧬DNA Language Models to Understand the Biology of Genomes 📅 March 5 📍 CECAD Lecture Hall ⏰ 2:30 PM Join us for fresh insights at the intersection of computational biology and genomics. Don't miss out!
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Anna Poetsch @apoetsch.bsky.social · 27/02/2026
Lieber @bundestag.de , für viele ist der #ÖPNV essenzielle Infrastruktur. Warum darf der überhaupt bestreikt werden?
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Björn Schumacher @bjornschumacher.bsky.social · 22/02/2026
🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...
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Björn Usadel @usadellab.bsky.social · 19/12/2025
Are you interested in @ceplas.bsky.social single cell data and spatial transcriptomic data analysis and inference? Then apply for this PhD position in our graduate school HDS-LEE in my group co-supervised by Prof Assent. www.fz-juelich.de/en/careers/j.... For questions don't hesitate to contact me.
fz-juelich.de
PhD position - Co-regulation structures for large-scale single-cell transcriptomics - within the HDS-LEE graduate school
The Bioinformatics Division of the Institute of Biological and Geosciences (IBG-4) processes and develops methods and algorithms to achieve a fundamental understanding of high-dimensional data and pro...
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Anna Poetsch @apoetsch.bsky.social · 11/02/2026
You did not get your #MSCA and you are upset, because you really wanted to work on somatic cell evolution on the way to malignancy with single cell data and 🧬machine learning 💻? Then get in touch! There are other ways to fund a postdoc ;-)
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Anna Poetsch @apoetsch.bsky.social · 05/02/2026
Are you interested to hear about DNA Language Models (in German)? Then I would have apodcadt for you. It was a really nice conversation and I hope you’ll like it! www.ghga.de/de/codedesle...
ghga.de
GHGA Podcast: Der Code des Lebens
Der Code des Lebens – der Wissenschaftspodcast von GHGA beschäftigt sich mit verschiedenen Aspekten der menschliche Genomforschung. Wie ist unser Erbgut entstanden? Wie funktioniert Genomforschung und...
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Craig Anderson @craigandersn.bsky.social · 14/11/2025
Come to Germany and do a PhD with DKFZ. You'll be supported by an international community doing amazing science in a fantastic place. I joined the DKTK from the UK 3 months ago and couldn't be happier with how easy it has been fitting in. The quality of work here is phenomenal and you should apply!
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Anna Poetsch @apoetsch.bsky.social · 04/11/2025
Congratulations @vakil-takhaveev.bsky.social @sturlalab.bsky.social and everyone else involved. It was really a pleasure to play a small part in it. I am looking forward to celebrating the next time we meet!
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Javier Santoyo @jsantoyo.bsky.social · 02/11/2025
Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome. #DNAoxidation #HumanGenome @natchembio.nature.com www.nature.com/articles/s41...
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Benjamin Schuster-Böckler @dagams.bsky.social · 21/10/2025
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
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Anna Poetsch @apoetsch.bsky.social · 01/10/2025
It was a pleasure to talk Genome Stability for a few days with the DFG - FOR5504 for. It is really exciting to see the community in and around Cologne looking for genome stability in whole organisms and the context of the sequence. I am excited about what else is going to come.
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Anna Poetsch @apoetsch.bsky.social · 27/09/2025
Me: I got a new type of compliment from an audience member: "Your talk was so Gen Z" My lab: This was not a compliment... Me: 🥲 (but..., but..., I still think it was meant to be one...)
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
spiegel.de
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
swr.de
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
There is a new Master of Physics of Life in the house. Congratulations, Adnan! Well done! It was really a superb Defense! @poldresden.bsky.social
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
swr.de
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
spiegel.de
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
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Anna Poetsch @apoetsch.bsky.social · 25/09/2025
Dear CRC TRR 341, thanks for having me. It was fascinating to learn more about the genomes of plants in their ecological context!
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Craig Anderson @craigandersn.bsky.social · 19/08/2025
Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position: jobs.dkfz.de/en/jobs/1679... You'll learn a lot and it'll be fun and interesting! #DKTK @dkfz.bsky.social @lmumuenchen.bsky.social
jobs.dkfz.de
PhD Student in Mutational Processes Driving Somatic Evolution
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Anna Poetsch @apoetsch.bsky.social · 12/08/2025
Exciting to see the @grunewaldlab.bsky.social finding new target candidates against metastases of Ewing sarcoma. It makes one wonder how general this pathway disruption might be and whether it may work with other sarcomas or metastatic cancers in general… 🤔
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Anna Poetsch @apoetsch.bsky.social · 31/07/2025
We are happy to present a new paper on gastric tumour evolution in response to peri-operative chemotherapy. www.biorxiv.org/content/10.1... 🧵 1/6
biorxiv.org
Tumor clone dynamics in gastro-esophageal cancer organoids reveal a non-genetic memory of neoadjuvant chemotherapy via downregulation of NFκB signaling
Adenocarcinomas of the gastroesophageal junction exhibit genetic and non-genetic heterogeneity that impact clinical outcomes, though the underlying mechanisms behind drug resistance remain poorly unde...
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Anna Poetsch @apoetsch.bsky.social · 30/07/2025
We are happy to present a new paper on the sequence dependence of 🧬-double strand breaks. www.biorxiv.org/content/10.1... 🧵 1/4
biorxiv.org
Using the DNA language model, GROVER, to parse sequence and epigenetic effects on genome stability
Genome stability is shaped by DNA sequence and epigenomic context, but their relative contributions to double-strand break (DSB) sensitivity remain unclear. We show that the DNA language model, GROVER...
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The Company of Biologists @biologists.bsky.social · 17/07/2025
This week, we are highlighting Helena Jambor, a prolific contributor to our community sites @the-node.bsky.social and @focalplane.bsky.social, as an extraordinary biologist. #100biologists @helenajambor.bsky.social
The Company of Biologists 100 logo to the left and QR code to the right.
 
Portrait of Helena Jambor to the left, text to the right
 
100 extraordinary biologists

Helena Jambor

Helena Jambor has written many 'How to' posts on the Node, presented a FocalPlane features... webinar and authored Perspective articles for Journal of Cell Science. Helena is an Associate Professor at the University of Applied Sciences of the Grisons, Switzerland, and is an advocate for accessibility and interpretability of image data.

#100biologists #biologists100
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TUD | Center for Molecular and Cellular Bioengineering (CMCB) @cmcb-tud.bsky.social · 08/07/2025
🚨 #JobAlert. please share: The DRESDEN-concept Genome Center (DcGC) 🧬 @dcgenomecenter.bsky.social is looking for the new Head of Facility! 🗓️ Deadline for applications: August 11 More information here ➡️ tud.link/fz5hr8 @tudresden.bsky.social @mpi-cbg.de
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Anna Poetsch @apoetsch.bsky.social · 26/06/2025
We have several open postdoc positions! We do computational biology 🧬🖥️ and deep learning to understand the genomics of genome instability and (somatic) genome evolution in ageing and cancer. Interested? 👉🏻 more details: tu-dresden.de/cmcb/biotec/...
tu-dresden.de
Open positions
We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
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Danny @dannybar.bsky.social · 13/06/2025
open.spotify.com/playlist/1As...
open.spotify.com
Woodstock.bio2 & Night Science 2025 playlist
Playlist · Vojtěch Svoboda · 99 items · 2 saves
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Elise Cutts @elisecutts.bsky.social · 11/06/2025
@odedrechavi.bsky.social says he wants to change science for the better. How? I’m still not quite sure. But 1.5 days into #TCTeAC, the plan seems to involve, among other things, walk-up songs, jumping, dancing, and a hefty serving of joy.
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Anna Poetsch @apoetsch.bsky.social · 10/06/2025
@helenajambor.bsky.social Making a point about the importance of data visualization. #theconferencetoendallconferences #TCTEaC
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Stein Aerts @steinaerts.bsky.social · 04/06/2025
The deadline for the VIB.AI group leader positions is approaching - send in your CV and short research plan before 14th June to start your BioML research lab in Leuven or Ghent
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Marketa Tomkova @marketatomkova.bsky.social · 28/04/2025
We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations. cutt.cx/YUoB We look forward hearing from you! #epigenetics #jobs
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Anna Poetsch @apoetsch.bsky.social · 11/04/2025
Are you interested in combing machine learning and 🧬 language models with multi-omics data to study somatic genome evolution? We have several open postdoc positions and look forward to hearing from you! tu-dresden.de/cmcb/biotec/... 🧬🖥️
tu-dresden.de
Open positions
We are looking for Postdocs! If you are interested in the lab in general as a postdoc, please feel free to apply with an open application, including a letter of motivation and a CV …
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TUD | Biotechnology Center (BIOTEC) @biotec-tud.bsky.social · 11/04/2025
🚨 #JobAlert Postdoc positions in @apoetsch.bsky.social group at BIOTEC. Combine #AI and #LLM with #omics data to study #genomics. More info ⬇️⬇️
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