iiinova — where your digital self keeps evolving

Marketa Tomkova

@marketatomkova.bsky.social

Group Leader at the Ludwig Cancer Research Institute, University of Oxford. Excited about cancer genomics, epigenomics, omics data integration, interdisciplinary and collaborative research. Mutational and non-mutational/epigenetic cancer driver mechanisms.

Posts Replies Media

Marketa Tomkova @marketatomkova.bsky.social · 05/09/2025

Please share: we’re recruiting a postdoctoral fellow – applications open until September 15! To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies. my.corehr.com/pls/uoxrecru...

my.corehr.com

Job Details

042

Marketa Tomkova @marketatomkova.bsky.social · 28/04/2025

What is the most common type of mutations, causing cancer and genetic diseases? C to T mutations in CpGs: Signature 1. What is the best understood mutational signature? Signature 1. Or is it? An intro thread about a paper we published last year... 🧵1/ www.nature.com/articles/s41...

nature.com

Human DNA polymerase ε is a source of C>T mutations at CpG dinucleotides - Nature Genetics

A new method called polymerase error rate sequencing (PER-seq) can measure the nucleotide misincorporation rate of DNA polymerases. DNA polymerase ε mutants produce an excess of CpG<TpG errors duri...

141

Marketa Tomkova @marketatomkova.bsky.social · 28/04/2025

We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations. cutt.cx/YUoB We look forward hearing from you! #epigenetics #jobs

11014