Reposted by Andreas Beyer GroupAkis (Argyris) Papantonis @akispapantonis.bsky.social · 01/09/2026Come and join us! 041
Reposted by Andreas Beyer GroupCologne Graduate School of Ageing Research @cga-age.bsky.social · 26/08/2026Do you want to start your PhD at the Cologne Graduate School of Ageing Research in 2027? 🗓️ Don't miss our deadline: November 3, 2026. To help you get started with your application, our wonderful PhD students and faculty members have some tips for you in our short video. Enjoy! 🍿 057
Reposted by Andreas Beyer GroupAshley Webb, PhD @aewebb.bsky.social · 21/08/2026The abstract deadline is coming up for the FASEB on Epigenetics and Aging! Oct 19-22 in Malahide, Ireland. Submit now to be considered for a short talk! Amazing lineup including Yang Shi @denadubal.bsky.social @brunetlab.bsky.social @bbparis1984.bsky.social and more! events.faseb.org/event/Chroma...events.faseb.orgHome - Chromatin and Epigenetics in Aging and DiseaseDiscover how epigenetics and transcription shape aging and disease, with new tools, therapies, and collaborations at this leading conference. 095
Andreas Beyer Group @beyerlab.bsky.social · 24/08/2026Apply now! This is a great opportunity for truly interdisciplinary research. 032
Reposted by Andreas Beyer GroupUniversität zu Köln @unicologne.bsky.social · 21/08/2026 🔬Researchers @beyerlab.bsky.social @cecad.bsky.social developed a method that enables damage to individual cells to be precisely quantified. It uses molecular markers and enables the detailed analysis of disease progression in individual tissue samples, such as a biopsy ➡️ uni.koeln/W5DU7 083
Andreas Beyer Group @beyerlab.bsky.social · 24/08/2026Our paper on mutation susceptibility along the human genome is out! 📜🎉Big congrats to Corinna Schmalohr, Yashna Paul and Nina Bundschuh from the Beyer-lab 🌟🍾Susceptibility for mutations is remarkably similar across tissues #CRC1310 #CRC1678 link.springer.com/article/10.1...link.springer.comDeterminants of mutation susceptibility along the genome are largely invariant across human tissues - Genome BiologyBackground The propensity for accumulating somatic mutations varies along the genome, which critically influences somatic mosaicism, tumor evolution and the potential role of somatic mutations in the ... 062
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 20/08/2026🚨 Publication Alert 🚨 New study from #CRC1678 members @beyerlab.bsky.social and @muellerrom.bsky.social maps kidney and liver disease using cell‑type‑specific damage scores. PDS/HDS track cell injury and reveal circadian disruption and a MASLD/NASH threshold. 🍾🥳 👉 www.cell.com/cell-genomic...cell.comCell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomicsPadvitski, Unger Avila, Chen et al. introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury,... 064
Andreas Beyer Group @beyerlab.bsky.social · 21/08/2026Paper out on single-cell damage scores.📜Quantify the damage of single podocytes or hepatocytes using their transcriptomes to study degenerative diseases. Big congrats to the Beyer-Lab members Tim Padvitski and Paula Unger 🍾🌟🎉 Thanks to all the fantastic collaborators! www.cell.com/cell-genomic...cell.comCell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomicsPadvitski, Unger Avila, Chen et al. introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury,... 172
Reposted by Andreas Beyer GroupBioconductor @bioconductor.bsky.social · 30/04/2026🚀 We’re excited to share the release of Bioconductor 3.23, featuring: ✅2418 software packages (94 new) ✅437 experiment data packages (5 new) ✅928 annotation packages ✅8 books (2 new) ✅28 workflows 🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_... 02413
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 16/04/2026We are excited to announce the #CRC1678 Summer Symposium! 🗓️ June 22, 2026 📍 Auditorium, MPI for Biology of Ageing, Cologne A student‑organized day of scientific exchange featuring CRC researchers and international invited speakers. 🔗 More information on our event website: uni.koeln/U7FHR 052
Reposted by Andreas Beyer GroupComputational Biology Group @compbiogroup.bsky.social · 01/04/2026SPACO, our tool for Spatial Component Analysis for Spatial Sequencing Data, is now available as R package on CRAN!🎉 Congratulations to the team!!! We also have a Docker image which is available on Zenodo. #SpatialTranscriptomics #DimensionalityReduction 132
Reposted by Andreas Beyer GroupCECAD Cologne @cecad.bsky.social · 01/04/2026📣#CECAD will host two exciting conferences 📆 11th - 14th October 2026 15th AHA Conference - “From mechanisms of age-associated diseases to healthy aging” uni.koeln/7X2K8 📆 14th - 16th October 2026 1stEFAR Conference - “On the Biology of Aging” uni.koeln/YGPMA 👉 Submit abstracts by May 31st 165
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 17/03/2026🚨 Publication Alert 🚨 New work from our #CRC1678 members @volkerboehm.bsky.social and Niels Gehring in @narjournal.bsky.social shows that SMG8 and SMG9 act as nonessential but crucial modulators safeguarding the efficiency and resilience of the NMD pathway. academic.oup.com/nar/article/...academic.oup.comSMG1:SMG8:SMG9-complex integrity supports efficient execution of nonsense-mediated mRNA decayAbstract. Nonsense-mediated mRNA decay (NMD) is a translation-dependent mRNA turnover pathway, which degrades transcripts containing premature termination 053
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 12/03/2026🚨 Speaker Alert! 🚨 We’re excited to welcome Christina Leslie to our upcoming #CRC1678 Seminar. 🧬AI models for regulatory genomics and spatial biology 📅 March 17 📍Auditorium, MPI-Age ⏰ 3:00 PM Join us to explore cutting‑edge AI models shaping regulatory genomics and spatial biology! 001
Andreas Beyer Group @beyerlab.bsky.social · 05/03/2026Big congratulations to our #CRC1678 partner Niels Gehring! Isn't it amazing how little we understand about the molecular mechanisms of something as important as NMD? Read this: www.nature.com/articles/s41...nature.comComposite SMG5-SMG6 PIN domain formation is essential for NMD - Nature CommunicationsExecution of mRNA cleavage in nonsense-mediated decay remained elusive. The authors show that SMG5 complements SMG6 to form a highly active, composite endonuclease with expanded catalytic center that ... 041
Andreas Beyer Group @beyerlab.bsky.social · 01/03/2026Thanks to @antebilab.bsky.social for involving us in this project! Beyer-lab member Francisco Lopes helped with the data analysis and came up with a cool way to study the stoichiometry control of ribosomal proteins. Read the preprint for more! 021
Reposted by Andreas Beyer GroupBjörn Schumacher @bjornschumacher.bsky.social · 22/02/2026Together with @spanier55.bsky.social and Boris Pfander we put together a great program with support of @cecad.bsky.social Cologne, @mpiage.bsky.social and the Fritz Thyssen Stiftung. Meeting site: www.for-5504.com/en/197/Confe...for-5504.comConference 2026 113
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 25/02/2026🚨Publication Alert🚨 New work from our #CRC1678 members Niels Gehring and @volkerboehm.bsky.social published in @natcomms.nature.com shows that SMG5 & SMG6 PIN domains form a composite endonuclease (cPIN) enabling efficient mRNA cleavage🧬 023
Reposted by Andreas Beyer GroupRoman-Ulrich Müller @muellerrom.bsky.social · 24/02/2026Looking forward to continuing the collaboration with @pkdinternational.bsky.social in this new position. 012
Reposted by Andreas Beyer GroupBjörn Schumacher @bjornschumacher.bsky.social · 22/02/2026🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe... 165
Reposted by Andreas Beyer GroupLeibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut @leibnizfli.bsky.social · 16/02/2026📢 PhD Positions - CALL FOR APPLICATIONS - 26/01 (m/f/d) The Leibniz Graduate School on Aging (LGSA) is a joint program of the @leibnizfli.bsky.social and the @uni-jena.de (FSU) in #Jena. The School calls for #applications for #PhD positions. 👇 ➡️ More: jobs.leibniz-fli.de/jobposting/c...jobs.leibniz-fli.de26/01 - LGSA - PhD candidates (m/f/x)The Leibniz Graduate School on Aging and Age-Related Diseases (LGSA) invites applications for a PhD candidate. 001
Andreas Beyer Group @beyerlab.bsky.social · 12/02/2026Beyer Group proudly presents: "Snow White and the Data Miners". It's so much fun to be part of Cologne Carnival! Thanks to all the costume designers and makers, especially to Paula and Jakub!!! 070
Andreas Beyer Group @beyerlab.bsky.social · 11/02/2026We are VERY much looking forward to the selection week and meeting the candidates! All of them are very smart people and we will have many inspiring discussions. 🎓 020
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 11/02/2026👩🔬 Today is International Day of Women and Girls in Science! Meet Lara Hitzemann @larahi.bsky.social , PhD student in the group of @beyerlab.bsky.social at the @unicologne.bsky.social 042
Andreas Beyer Group @beyerlab.bsky.social · 11/02/2026Big thank you to all those female researchers from #CRC1678 sharing their thoughts in this series! 🙏 #WomenInScience #GirlsInSTEM 020
Andreas Beyer Group @beyerlab.bsky.social · 11/02/2026!!!!!!!!!!!! 👩🔬👩🔬👩🔬👩🔬 Imagine all of the Beyer Lab papers with female first authors were gone: what would our publication track record look like? 020
Reposted by Andreas Beyer GroupIna Huppertz @inahuppertz.bsky.social · 06/02/2026Amazing to have you here! I am looking forward to work together on #RNA and #ageing @mpiage.bsky.social 071
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 05/02/2026🚨 Publication alert 🚨 Check out this brand new review article about Proteostasis of organelles in aging and disease in @febsj.bsky.social. Congratulations to our #CRC1678 members @thevilchezlab.bsky.social and Yara Nabawi and everyone else involved🎉 041
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 03/02/2026🚨Publication Alert🚨 New work from our #CRC1678 members @bjornschumacher.bsky.social and @meyerdh.bsky.social reveals why some neurons age faster. Using neuron‑specific aging clocks, they identified vulnerable neurons and highlight syringic acid and vanoxerine as promising neuroprotective hits.🧬 043
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 28/01/2026🚨Hot off the press from #CRC1678 's @ignatovalab.bsky.social 🚨 A brand‑new paper published in @narjournal.bsky.social introduces ADAM‑tRNA‑seq, a powerful framework that finally brings accuracy and scalability to Nanopore‑based direct tRNA sequencing. Congratulations! 🥳 042
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 26/01/2026🚨 Speaker Alert! 🚨 We’re thrilled to welcome Duygu Ucar for an upcoming joint #CRC1678 / #CECAD Seminar about “Heterogeneity in Human Immune Aging and Vaccine Responses”. 📅 February 4 📍 CECAD Lecture Hall ⏰ 2:30 PM Join us for fresh insights into the complexity of human immune aging! 021
Reposted by Andreas Beyer GroupAndreas Beyer Group @beyerlab.bsky.social · 17/01/2026One of the greatest computational biologists of Germany - of the world I should say. He majorly shaped the field, never got stuck in one corner of science, but kept exploring new areas due to his curiosity, always aimed to understand the biology, and trained generations of scientists. 0102
Reposted by Andreas Beyer GroupJo Wolff @jowolff.bsky.social · 21/11/2024I’ve changed my header photo to this one. It shows my father Herbert and his sister Lotte with their parents Fritz and Marta in their Frankfurt apartment before Herbert and Lotte were sent to England on the Kindertransport, and later Fritz and Marta transported to Lodz Ghetto, final fate unknown. 831470182
Reposted by Andreas Beyer GroupPicotti Lab @picottilab.bsky.social · 13/01/2026We’re delighted to report a global structural proteome analysis within living cells! doi.org/10.1038/s443... #proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social 12921
Andreas Beyer Group @beyerlab.bsky.social · 25/12/2025Congrats to our #crc1678 member Akis @akispapantonis.bsky.social for this very nice Christmas gift🎄 040
Reposted by Andreas Beyer GroupDavid Meyer @meyerdh.bsky.social · 19/12/2025Happy to share our recent publication, which grew out of a consulting job I did last year: www.nature.com/articles/s41... 🧵nature.com 152
Reposted by Andreas Beyer GroupLara Hitzemann @larahi.bsky.social · 10/12/2025Three amazing months at @ethz.ch🏔️ in the @picottilab.bsky.social thanks to funding by @crc1678.bsky.social! Working on large-scale LiP-MS data and developing methods to identify structurally co-varying peptides. Grateful to @crc1678.bsky.social, @picottilab.bsky.social & @beyerlab.bsky.social! 062
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 04/12/2025Three #CRC1678 PhD students joined Lena Breuer’s ImproKoeln workshop 🎤 last week, learning improvisation, camera presence & interview skills. They’re now ready to spotlight diverse scientific journeys in our upcoming #DiversityInScience video campaign! 031
Reposted by Andreas Beyer GroupBjörn Schumacher @bjornschumacher.bsky.social · 02/12/2025This was a great start of the @erc.europa.eu Synergy funded @batprotect.bsky.social BATPROTECT workshop @cecad.bsky.social @unicologne.bsky.social in Cologne 081
Reposted by Andreas Beyer GroupLeibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut @leibnizfli.bsky.social · 02/12/2025Congratulations! 👏 Dennis de Bakker from @leibnizfli.bsky.social received the LIFE Talent Award 2025 at the “4th LIFE Symposium – Time to connect”, which took place on November 26, 2025, in #Jena. Photos: Anna Schroll With @uni-jena.de 082
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 01/12/2025🚀 New on the #CRC1678 Website! 🌐 Explore Job Opportunities + Fellowships: - Postdoc Position🔬 - Medical Research Fellowship (6 months)👩⚕️ - PhD Orientation Fellowship(4 months)🎓 📅 Open year-round, no deadline, open to all! 👉 crc1678.uni-koeln.de/job-opportun...crc1678.uni-koeln.deJob Opportunities - CRC1678 - Collaborative Research CenterThe CRC1678 offers exciting career opportunities for researchers at different stages of their academic path. Positions within the CRC provide the chance to 052
Reposted by Andreas Beyer GroupBjörn Schumacher @bjornschumacher.bsky.social · 26/11/2025🔥🔥🔥Now out in print: how do germ cells instruct the soma and how does the soma impact inheritance? Together with Shoma Ishikawa we provide a comprehensive overview of The Somatic Impact on Inheritance and the Germline Control of the Soma - www.annualreviews.org/content/jour...annualreviews.orgThe Somatic Impact on Inheritance and the Germline Control of the SomaThe faithful transmission of genomic DNA over succeeding generations is an essential prerequisite for species maintenance. The germplasm theory by August Weismann has been foundational for the current... 063
Reposted by Andreas Beyer GroupCRC1678 @crc1678.bsky.social · 27/11/2025🚨 Postdoc Opportunity within the #CRC1678 - @riemerlab.bsky.social 🔬 Study redox regulation & proteome plasticity via translation initiation 📅 Start: March 2026 (or later) 💼 100% E13 funded 👉 Apply now to explore molecular mechanisms in mammalian cells: crc1678.uni-koeln.de/job-opportun...crc1678.uni-koeln.deJob Opportunities - CRC1678 - Collaborative Research CenterThe Riemer Lab within the CRC1678 (Project B03) is seeking a highly motivated postdoctoral fellow to join a project focused on redox regulation of cellular 041
Reposted by Andreas Beyer GroupTrentini Lab @trentini-lab.bsky.social · 26/11/2025We had a fantastic time at the Ribo-Seq workshop in Bonn. Thanks so much, Kathrin @katleppek.bsky.social and Ranen, for organizing! We learned a lot, and we're excited to use Ribo-Seq in future projects. 073
Reposted by Andreas Beyer GroupR Ladies St. Louis @r-ladies-stl.bsky.social · 17/11/2025Hello #rstats! 👋 Do you have an #rstats package or skill or strategy you love and would be willing to share with the @rladies.org community? We are looking 👀 for a couple more speakers 🔊 for the 2025–2026 R-Ladies St. Louis season. Reply here and we will contact you to find a date! 💜 💜 💜 1289
Reposted by Andreas Beyer GroupRiemerLab @ UoCologne @riemerlab.bsky.social · 17/11/2025Nice work together with the @jaelab.bsky.social on Fam136A as a novel Disulfide Relay substrate and guardian of proteostasis in the mitochondrial IMS - www.sciencedirect.com/science/arti.... Accompanied by a small graphical abstract… 1144
Reposted by Andreas Beyer GroupIna Huppertz @inahuppertz.bsky.social · 19/11/2025Last Friday, we had an inspiring 10th Rhineland RNA Club meeting with top class speakers. It's great to see how the community is growing and the range of topics we're covering. Special thanks to Didier Stainier @stainierlab.bsky.social Simon Bekker-Jensen @bekkerjensenlab.bsky.social, Ranen Aviner! 1206
Reposted by Andreas Beyer GroupUniversität zu Köln @unicologne.bsky.social · 31/10/2025How Leucine boosts energy production! 🚀 A research team around Professor Dr Thorsten Hoppe at @cecad.bsky.social has discovered how the amino acid Leucine from food increases cell energy and opens up new possibilities for treating metabolic diseases. 🌟 Read more 👇 uni.koeln/XMMXSuni.koelnFrom food to fuel: How leucine enhances mitochondrial energy productionResearchers from the University of Cologne discovered how a specific dietary amino acid increases cellular energy, opening new possibilities for treating metabolic diseases 131
