The eruption of Vesuvius volcano witnessed by Pliny the Younger in 79 CE is dated by the argon-40/argon-39 (40Ar/39Ar) method to 1938 ± 13 years (SD) before measurement in 2025 CE. Achievement of 0.7%...

All kingdoms of life have developed strategies to limit viral infection. In humans, interferons induce a suite of antiviral factors that collectively provide immunity. Some human immune genes are homo...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Broad-spectrum antibiotics are frequently administered to intensive care unit patients as part of empiric care. This treatment has been associated ...

Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center

A bile acid-bound structure of toxin TcdB revealed the mechanism of inhibition and guided the design of a synthetic bile acid that alleviated Clostridioides difficile infection in mice.

Long-standing myths about “silly science” have contributed to the reckless slashing of government-supported research.

Mass spectrometry data mining tools enabled the creation of an MS/MS spectral library containing hundreds of N-acyl lipids, including conjugates with short-chain fatty acids. This resource enabled the...

Dear Members of the Harvard Community,Over the course of the past week, the federal government has taken several actions following Harvard’s refusal to

While university officials said they’ve still not received official word of such action, they acknowledged receiving about 100 stop-work orders from the federal government on roughly 100 fede…

Scientists, with expertise in fields that include mental health, cancer and infectious disease, typically serve five-year terms and were not given a reason for their dismissal.

President Trump and GOP members of Congress have accused the public broadcasters of biased and "woke" programming. The president plans a rescission, which would give Congress 45 days to approve the di...

Clostridioides difficile is a master scavenger. Munneke et al. discover a pyrimidine analog in the vertebrate gut, and 4-thiouracil can be used by C. difficile as a nutrient to outgrow neighboring bac...

Molecular oxygen diffuses across membranes with such speed that, despite respiration, the intracellular oxygen concentration does not differ significantly from that outside the cell. In contrast, mem...

Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of…

Promoting inclusion and diversity is fundamental to the advancement of science. It results in the incorporation of diverse perspectives and increases engagement from a wider community of researchers. ...