The TERM Research Technician is part of the Behringer Lab in the Department of Biological Sciences at Vanderbilt University and is a key member of the research team responsible for supporting the rese...

Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...

Optimal cephalexin and cefadroxil dosing for skin and soft tissue infections (SSTIs) is unclear. We summarize clinical and pharmacokinetic/pharmacodynamic (PK/PD) data that compare dosing strategies ...

In this session, Dr. Jeffrey Freiberg reviews findings from the Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin (STOP-Vanc) randomized controlled trial. He explores the role of MR...

In this pragmatic randomized trial of 277 adults, vancomycin-free hours alive in the first 7 days of trial enrollment did not significantly differ between

In Tennessee, hospitalizations for injection-related infections disproportionately affected eastern Tennessee, and plateaued in 2018. Hospitalizations for

The NPV of MRSA PCR nasal swabs is not diminished after mupirocin decolonization. MRSA PCR testing within 7 days of initiation of decolonization is non-inferior to testing prior to decolonization.

β-lactam antibiotics are among the most widely used treatments for bacterial infections, yet therapeutic failure is common even when no genetic resistance is detected. Understanding how host factors...

The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.

This narrative review summarizes current evidence on the epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment of Staphylococcus aureus bacteremia.

This review covers important public health notices and clinical trials covering a broad range of infectious diseases topics from October 2023 to September

Jeffrey Freiberg, MD, PhD review of the SABATO trial on oral antibiotics for S aureus bacteremia and a comparison of mupirocin and iodine treatments for MRSA decolonization.

Jeff Freiberg, MD, PhD review on key trials and challenges from 2024 in the fight against antibiotic resistance in complicated and uncomplictaed UTIs, including cefepime-taniborbactam and gepotidacin.

Jeff Freiberg, MD, PhD, on the rising emerging infection concerns of dengue, mpox, measles, and H5N1 influenza in clinical practice.

Background Vancomycin, an antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA), is frequently included in empiric treatment for community-acquired pneumonia (CAP) despit...

Nature Communications - The immunologic differences induced by bactericidal versus bacteriostatic antibiotics remain unclear. Gross et al. show that, in contrast to static antibiotics, cidal...