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This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma mansoni infection, designed...

The helminth immunomodulators from the HpARI and HpBARI families can block IL-33 responses. Smyth and Hodge et al. show that vaccination with these immunomodulatory proteins can raise blocking antibody responses against them, allowing the development of effective anti-parasite type 2 immunity and ejection of the parasite.

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