Polymorphisms of human leukocyte antigen (HLA) genes confer risks for human diseases. Predisposing effects related to T cell receptor (TCR) recogni...

Mucosal-associated invariant T (MAIT) cells are an unconventional subset of T cells that respond to vitamin B2 metabolites from a range of bacteria and fungi. We have previously reported that peripher...

Abstract. Chemokine CCL20, secreted by gut epithelial cells, demonstrates markedly increased expression during episodes of chronic inflammation and infecti

<p>Dr. Rossana Azzoni is in the Author&rsquo;s Corner with Kathryn Knoop to discuss her work&nbsp;<a href='https://www.mucosalimmunology.org/article/S1933-0219(26)00037-1/fulltext'><u>Allergic lung in...

Join us in 2026 in Canmore, AB, Canada for a 2.5 day in-person symposium dedicated to microbiome research.

The complement system is an evolutionarily conserved arm of innate immunity, which forms one of the first lines of host response to pathogens and assists in the clearance of debris. A deficiency in ke...

Metastatic breast cancer accounts for 7% of cancer-related deaths, with the lungs being a common site of cancer spread. In parallel, lower respirat...

The Janus Kinase inhibitors Tofacitinib, Upadacitinib and Filgotinib are used for the treatment of ulcerative colitis but the full mechanism of their action is not completely elucidated. Here the auth...

The spatial distribution of adaptive immune cells is a critical determinant of the quality and magnitude of mucosal immunity. Here, we present a protocol for tyramide signal amplification (TSA) immuno...

Bacille Calmette–Guérin (BCG) is the only licensed vaccine against tuberculosis (TB) but provides inconsistent protection against disease. Alveolar macrophages (AM) are widely considered the primary m...

LTβR blockade curbs CD137-driven hepatotoxicity by promoting effector CD8 T cell contraction while preserving anti-tumor immunity.

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Despite their importance, dendritic cell subsets are not well characterised in neonates. We here provide fundamental information on the abundance and phenotype of small-intestinal neonatal DCs and as...