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Lydia Lynch

@lydialynch.bsky.social
2.3K followers 547 following 31 posts

Professor at Princeton University. Immunologist, Irish Mammy, Optimist

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Reposted by Lydia Lynch
cniostopcancer.bsky.social @cniostopcancer.bsky.social · 13/02/2026
Obesity, adipose tissue, and systemic metabolism in cancer on the first session of #CFM_MetCanc.  Speakers:  Paul Cohen @rockefeller.edu  Stephan Herzig @helmholtzmunich.bsky.social @lydialynch.bsky.social @ludwigcancer.bsky.social ✍️ bit.ly/45jaORu  Sponsored by @caixaresearch.bsky.social
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Reposted by Lydia Lynch
Fusion Conferences @fusionconf.bsky.social · 09/02/2026
Our next #FusionMetabolism meeting unites researchers across the spectrum; from investigating individual molecules to carrying out population studies & clinical trials👩‍🔬 Submit by 13 April 2026 to join the line up ➡️https://bit.ly/45CT3MY @petemullen.bsky.social @annakrook.bsky.social
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Lydia Lynch @lydialynch.bsky.social · 01/10/2025
Super brilliant talk by Shruti @drshrutinaik.bsky.social visiting us in Princeton today 🐅 @princetonmolbio.bsky.social on new frontiers for the immune system in health, and co-opted in disease
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Lydia Lynch @lydialynch.bsky.social · 19/09/2025
He’s a doctor 🎉 Congratulations Dr Martin Brennan @princetonmolbio.bsky.social @tbsi-tcd.bsky.social We’re going to miss him so much! Onwards and upwards
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Reposted by Lydia Lynch
Science Blog @scienceblog.com · 18/03/2024
Diabetes drug metformin causes weight loss by triggering the production of an "anti-hunger" molecule called lac-phe, also produced after vigorous exercise. #Metformin #WeightLoss #LacPhe #GutBrainConnection
scienceblog.com
Metformin's Weight Loss Effect Linked to "Anti-Hunger" Molecule Produced During Exercise
A new study conducted by researchers at Stanford Medicine and Harvard Medical School has found that the diabetes medication metformin causes weight loss
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Lydia Lynch @lydialynch.bsky.social · 28/07/2025
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...
nature.com
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
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Lydia Lynch @lydialynch.bsky.social · 25/07/2025
Happy summer from Princeton. Feeling very lucky ☘️🐅
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Reposted by Lydia Lynch
Lisa Situ @lisasitu.bsky.social · 11/06/2025
ICYMI: Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer, a #ResearchWatch summary of a new study by @karen--s.bsky.social, @lydialynch.bsky.social, and colleagues at @ludwigcancer.bsky.social @princetonmolbio.bsky.social aacrjournals.org/cdnews/news/...
aacrjournals.org
Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer
Major Finding: Lipids derived from ascites are taken up by NK cells and drive NK cell dysfunction in ovarian cancer. Concept: Polar lipids such as phosphatidylcholine disrupt NK plasma membrane order ...
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Reposted by Lydia Lynch
γδ T cell Forum @forum-gd.bsky.social · 04/06/2025
www.nature.com/articles/s41... @jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social
nature.com
Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy
Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...
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Reposted by Lydia Lynch
Harvard T.H. Chan School of Public Health @hsph.harvard.edu · 16/05/2025
With nearly all of Harvard Chan School’s direct federal grants terminated, we are relying on philanthropy to power our research and support our educational programs. Every gift, regardless of size, advances our vision of health, dignity, and justice for every human. Support our work: hsph.me/whygive
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Lydia Lynch @lydialynch.bsky.social · 12/05/2025
Our paper @sciimmunology.bsky.social shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy in ovarian cancer. Wonderful to collaborate with Donal Brennan, Marcia Haigis & super postdoc @karen--s.bsky.social
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Reposted by Lydia Lynch
Ludwig Cancer Research @ludwigcancer.bsky.social · 09/05/2025
Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU
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Lydia Lynch @lydialynch.bsky.social · 24/04/2025
A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social
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Lydia Lynch @lydialynch.bsky.social · 24/04/2025
Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @tjryan.bsky.social @tcddublin.bsky.social @tbsi-tcd.bsky.social ….. mice remember cold 🐭📝❄️
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Reposted by Lydia Lynch
Dr. Jessie Christiansen @aussiastronomer.bsky.social · 09/03/2025
HANG IT IN THE LOUVRE. (President of Mexico on International Women’s Day)
Claudia Scheinbaum, President of Mexico, in the centre of the image in a purple dress on International Women’s Day, 2025. A search around on google fails to turn up an image credit unfortunately, I found it on Reddit: https://www.reddit.com/r/AccidentalRenaissance/s/MGhF9O80FL
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Reposted by Lydia Lynch
Jack Iwashyna @iwashyna.bsky.social · 08/03/2025
NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social
g.co
Google Search
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Lydia Lynch @lydialynch.bsky.social · 07/03/2025
Thank you to our colleagues in France ❤️🇫🇷❤️🇺🇸❤️ #standupforscience
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Lydia Lynch @lydialynch.bsky.social · 07/03/2025
Thank you to our colleagues @pasteur.fr Paris 🇫🇷🥼🧪 #standupforscience
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Lydia Lynch @lydialynch.bsky.social · 07/03/2025
Thank you to our colleagues in Geneva #standupforscience
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Reposted by Lydia Lynch
Eric Topol @erictopol.bsky.social · 01/03/2025
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
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Lydia Lynch @lydialynch.bsky.social · 27/02/2025
So happy to have @aiinglim.bsky.social as a colleague at Princeton! Her immunology is so exciting and original 😍 Great talk at Princetons ‘Quantitative Immunology’ Symposium today @princetonmolbio.bsky.social
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Reposted by Lydia Lynch
E John Wherry @ejohnwherry.bsky.social · 26/02/2025
First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork
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Lydia Lynch @lydialynch.bsky.social · 24/02/2025
Congratulations to the amazing @karen--s.bsky.social ! And many thanks to @irishcancersociety and Prof Donal Brennan in @ucddublin.bsky.social for continued collaboration on gynaecological cancer research
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Lydia Lynch @lydialynch.bsky.social · 23/02/2025
Almost ready to kick off the 3rd Fusion Mitochondria Conference in DR 🇩🇴🌴☀️🧬🧪🧫 @fusionconf.bsky.social with @MarciaHaigis
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Lydia Lynch @lydialynch.bsky.social · 21/02/2025
Hello DR 🇩🇴 just like Ireland, but 85degrees F! Can’t wait fo r the @fusionconf.bsky.social Mitochondria Conference!
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Lydia Lynch @lydialynch.bsky.social · 15/02/2025
We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025
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Lydia Lynch @lydialynch.bsky.social · 14/02/2025
No one could be more deserving. The Immunology community is so proud of you @belkaidlab.bsky.social
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Lydia Lynch @lydialynch.bsky.social · 04/02/2025
Fantastic thought provoking talk today by @itaiyanai.bsky.social at 🐅 @princetonupress.bsky.social ….first how we lost our tails against strong pressure, and then how cells develop resistance to drugs 🧫🧬🧪
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Lydia Lynch @lydialynch.bsky.social · 16/01/2025
Thank you to @mcsinton.bsky.social @juanquintana.bsky.social and co-authors for this spotlight on the amazing IL-17 😊
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Reposted by Lydia Lynch
Waggoner Lab @labwaggoner.bsky.social · 31/12/2024
Service to the scientific community @cp-immunity.bsky.social www.cell.com/immunity/ful...
cell.com
Service
There are many dimensions to scientific life. We asked investigators about the impact of service to the scientific community and beyond and how service has shaped their experience, perspective, and research path.
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Lydia Lynch @lydialynch.bsky.social · 19/12/2024
Happy Holidays from the Lynch Lab. Very grateful to work with these wonderful people everyday, and grateful for our first year in @PrincetonUniversity 🐅🥳🎄
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Lydia Lynch @lydialynch.bsky.social · 19/12/2024
Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @natureportfolio.bsky.social Huge effort by whole team and collaborators to work this out. www.nature.com/articles/s41...
nature.com
Article Metrics - Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis | Nature
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Lydia Lynch @lydialynch.bsky.social · 02/12/2024
She’s here ! 😍
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Reposted by Lydia Lynch
Ivan Zanoni @lozanzi.bsky.social · 21/11/2024
#TickTock 🕰️! Douglas, @lydialynch.bsky.social &co show @ Nature @natureportfolio.bsky.social that IL17 production, especially by gd T cells, has a circadian rhythm impacting lipogenesis. Disruption of the clock or of the IL17 axis alters whole body metabolism & temperature! t.co/wMgOdScsiV
t.co
https://www.nature.com/articles/s41586-024-08131-3
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