New paper challenges old notions of ‘glitched brain’ idea of delusions and instead focuses on physical experiences of strong and deeply held emotion.

Animals must balance exploration with threat avoidance, yet how neuromodulatory signals shape information-seeking states remains unclear. Using fibre photometry recordings in the basolateral amygdala ...

Brain imaging across more than 1,200 people identifies two reproducible reward profiles, one tuned to cues and one to outcomes. The two profiles respond in opposite ways to dopamine-blocking drugs, an...

Objectives Patients with major depressive disorder (MDD) frequently report burdensome interpersonal difficulties and altered empathy and perspective-taking. Previous findings on binary comparisons b.....

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Leading the science of software success

Long-read sequencing enables comprehensive transcriptome characterization but remains challenging to benchmark due to sequencing errors, sample variability, and the limited scope of existing evaluatio...

Better Code, Better Science: Chapter 9, Part 7

Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...

Molecular Psychiatry - Neuroanatomy reflects individual variability in impulsivity in youth

If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

Respiration has been shown to impact memory retrieval, yet the neural dynamics underlying this effect remain unclear. Here, we investigated how respiration shapes both behavioral and neural expression...

Brain levels of the agouti gene determine whether African striped mice are doting fathers—or infanticidal ones.

Cognitive health in later life is ‘strongly influenced’ by lifelong exposure to intellectually stimulating environments, say researchers

How humans process competing information when making multi-alternative decisions remains unclear. Here, the authors show that the brain resolves the trade-off between “evaluating within” and “comparin...

David Anderson’s 2013 paper revealed the sensory neurons involved in pleasurable touch and led Ishmail Abdus-Saboor down a new research path.

Better Code, Better Science: Chapter 7, Part 8

Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.

‘Exercise snacks’ and other forms of everyday movement can greatly reduce the risk of heart disease and death.

The force-activated ion channels underlie the senses of touch and proprioception. Now scientists are using them as a tool to explore molecular mechanisms at work in internal organs…

The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity, not cytoarchitecture, organizes prefrontal function.

An analysis of NeurIPS 2025 papers by startup GPTZero reveals how AI-generated citations are slipping into elite academic research.

The literature assumes that intergroup contact is naturally occurring, positive and consistently associated with positive outcomes, but these premises are inconsistent with everyday intergroup contact...

Author summary Perceiving the world requires humans to organize perceptual stimuli according to the likely sources that generated them, requiring inference about these sources and their relationship w...