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Alexa Sadier

@aigverte.bsky.social
1.6K followers 994 following 292 posts

CNRS PI at Institut des Sciences de l'Evolution de Montpellier | Evo-devo - Bats - Teeth - Dev Constraints - Adaptation | Evolution on Earth and beyond | ERC NOVELTEETH | Co-host @podcastscience | Cham steepskier website: alexasadier.com

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Reposted by Alexa Sadier
Prosanta Chakrabarty @prosanta.bsky.social · 8h
Exciting news! We here at the LSU Museum of Natural Science @lsumns.bsky.social and Dept. of Biological Sciences are looking for Curator and Assistant Professor of Vertebrate Paleobiology! Come work with us! We are fun, supportive and active! lsu.wd1.myworkdayjobs.com/en-US/LSU/jo...
lsu.wd1.myworkdayjobs.com
Assistant Professor
All Job Postings will close at 12:01a.m. CST (1:01a.m. EST) on the specified Closing Date (if designated). If you close the browser or exit your application prior to submitting, the application progre...
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Ken Welch @kcwelch.bsky.social · 11h
Just published! 🦇wings are big and thin, and likely represent an important route of exposure for sprayed pesticides! Great work led by Dr. Natalia Sandoval-Herrera! @utscbiology.bsky.social @utsc.utoronto.ca 🧪 linkinghub.elsevier.com/retrieve/pii...
linkinghub.elsevier.com
Redirecting
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Michael Wong @miquai.bsky.social · 12h
As an astrobiologist, I never thought I’d see my name on a cancer paper...but here we are 😮
academic.oup.com
Exploring tumorigenesis as a process of phenotypic state-space exploration and selective funneling
Abstract. Tumorigenesis is widely studied within evolutionary frameworks, yet integrating genetic, non-genetic, spatial, and collective tumor-level dynamic
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Le Monde @lemonde.fr · 29/09/2026
Salaire des enseignants : quarante ans de décrochage qu’aucune mesure n’a permis de freiner
lemonde.fr
Salaire des enseignants : quarante ans de décrochage qu’aucune mesure n’a permis de freiner
Les 850 000 professeurs sont appelés à la grève mardi 29 septembre, pour revendiquer des hausses de rémunération. Leur pouvoir d’achat s’est effondré depuis les années 1980, et leur situation ne s’est pas améliorée après la revalorisation de 2023. Ils touchent en moyenne 900 euros net de moins que les autres fonctionnaires de catégorie A.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Podcast Science @podcastscience.fm · 28/09/2026
Un départ tout en douceur pour #Podcast #Science Nouvel épisode sorti du four ! 🍰🥳 Sur la thématique du sucré 🍨 Un avant-GOÛT des très prochaines Radio-Dessinées du 3-4 octobre qui arrivent (vous pouvez toujours vous y inscrire !) À déguster dès maintenant 🍫 : www.podcastscience.fm/emission/202...
Photo d'illustration de gâteaux sucrés en forme de cœur sur lequel est écrit "I love u" et "Love !"
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Reposted by Alexa Sadier
Podcast Science @podcastscience.fm · 23/09/2026
Ce soir, ce mercredi 23 septembre 20h30 (UTC+2) #Podcast #Science 🎙️ revient tout en douceur pour une nouvelle saison. 🥰 Douceur, car on va parler du : SUCRÉ 🍭🍫🍨 On enregistre le prochain épisode en live avec vous, ça vous dit ? 👀 Lien vers le live en commentaire ⬇️
La photo d'illustration montre des gâteaux sucrées en forme de cœur sur lequel est écrit "I love u" et "Love !"
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Pierre Kerner @ssaft.com · 28/09/2026
C'est la rentrée pour @podcastscience.fm ! www.podcastscience.fm/emission/202... Et pour l'occasion, je vous ai concocté une chronique tout en plumes, à lire sur SSAFT : ssaft.com/Blog/dotclea... Ft. Zizi Jeanmaire mais aussi des convergences évolutives, des piafs et beaucoup de sucre !
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franceinfo @franceinfo.fr · 28/09/2026
En charge des crèches, des collèges, de la protection de l'enfance, des aides aux personnes âgées ou handicapées et du RSA, ces agents estiment avoir épuisé tous les recours d'alerte en interne. En sous-effectifs constants, ils dénoncent des conséquences graves sur les salariés et leurs missions.
l.franceinfo.fr
INFO RADIO FRANCE. Une plainte au pénal déposée au nom des 7 500 agents du conseil départemental du Val-de-Marne pour harcèlement moral institutionnel
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Development @dev-journal.bsky.social · 27/09/2026
The curious case of the placental genome In this Review, Zoé Ducarne, @agathechaigne.bsky.social and @myanhtruong.bsky.social highlight the placenta, the only mammalian organ that harbors a cancer-like genome while remaining functional and healthy. doi.org/10.1242/dev....
Diagrams of a blastocyst and full-term placenta in human. More details in the paper.
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CNRS @cnrs.fr · 27/09/2026
Les chauves-souris présentent l’une des plus incroyables trajectoires d’évolution chez les mammifères. On en connaît plus de 1500 espèces ! Comment cette diversité est-elle apparue ? Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. Reportage avec lemonde.fr
lejournal.cnrs.fr
Les chauves-souris, laboratoires de l’évolution
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Dávalos Lab @labdavalos.bsky.social · 27/09/2026
And here’s the paper: elifesciences.org/reviewed-pre...
elifesciences.org
Client Challenge
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bioRxivpreprint @biorxivpreprint.bsky.social · 25/09/2026
MERFISHEYES: Web-based Visualization and Sharing Platform for Single-cell and Single-molecule Spatial Transcriptomics www.biorxiv.org/content/10.64898/20…
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Alexa Sadier @aigverte.bsky.social · 25/09/2026
C'est sorti ! Un reportage des équipes du CNRS sur nos recherches et l'importance d'étudier la diversité des chauves-souris et leur evolution. Une occasion aussi de découvrir la splendeur de Trinidad et nos collaborateurs grâce aux images de notre film Spectral @erc.europa.eu @isemevol.bsky.social
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CNRS @cnrs.fr · 25/09/2026
INÉDIT 🎬 Comment les chauves-souris ont-elles donné naissance à une telle diversité ? 🦇 Avec plus de 1500 espèces, leur évolution est fascinante. Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴 Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
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Journal of Experimental Biology @jexpbiol.bsky.social · 25/09/2026
If you're an ECR or postdoc in need of funding to travel for an experiment or to learn a new technique, make sure you apply for a JEB Travelling Fellowship www.biologists.com/grants/trave... #PostdocAppreciationWeek #NPAW #PostdocAppreciation Find out more at doi.org/10.1242/jeb....
National Postdoc Appreciation Week logo. September 21-25, 2026
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MadScientist @mads100tist.bsky.social · 25/09/2026
This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪
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Sonja Vernes @sonjavernes.bsky.social · 23/09/2026
🦇 Bat1K's biggest paper yet is out. Largest bat genome + fossil study ever: 103 genomes, 44 fossils, 137 researchers. We rewrote the bat family tree! Bats likely originated in Europe ~65 million years ago, not Asia, Africa or Americas. @bat1kgenomes.bsky.social doi.org/10.1038/s41586-026-11007-3
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Bat1K Genome Project @bat1kgenomes.bsky.social · 23/09/2026
Where did bats come from?🦇🌍 After decades of debate, the biggest bat genome + fossil study ever done has an answer - and it’s not where anyone expected! 🤩OUR PHASE 1 FLAGSHIP is out today in nature! doi.org/10.1038/s415... A thread 🧵
doi.org
Reference genomes and fossils revise bat family phylogeny and biogeography - Nature
An updated phylogeny of bats is presented, based on new genome assemblies and many ancient fossils and including all known bat families.
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James Briscoe @jamesbriscoe.bsky.social · 22/09/2026
Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach briscoelab.org/blog-quantif...
briscoelab.org
Quantifying Waddington's Landscape | Briscoe Lab
I have written before about how two conceptual frameworks have shaped our thinking about cell fate, Waddington's epigenetic landscape and Davidson's gene...
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Richard Lenski @relenski.bsky.social · 22/09/2026
"Philosophy of Biology: The power of theory in the life sciences" elifesciences.org/articles/112... @zdblount.bsky.social shared this thought-provoking paper with the lab group.
elifesciences.org
Philosophy of Biology: The power of theory in the life sciences
Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
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Nicolas Di-Poi @nicolasdipoi.bsky.social · 22/09/2026
Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S... @helsinki-biotech.bsky.social @helsinki.fi
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Ben Parker @ben-parker.bsky.social · 21/09/2026
Excited that our new paper with @henrylabsymbio.bsky.social and Kerry Oliver is out @pnas.org! We show that mobile genetic elements can spread adaptive host-benefiting traits across heritable insect symbionts on eco-evolutionary timescales.🧵 www.pnas.org/doi/10.1073/...
pnas.org
Phenotypic divergence is driven by mobile genetic elements in a heritable insect symbiont | PNAS
Heritable microbes profoundly influence insect biology, yet the traits they confer often evolve rapidly and differ among closely related symbiont s...
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Dr Mark D. Scherz @markscherz.bsky.social · 21/09/2026
🚨We're hiring a new Curator of Mammals!!🚨 🦍🐕🦝🐅🦓🦌🐃🐖🐏🐫🐘🦏🦛🐿️🦔🦇🦥🦦🦨🦘🦡🐋🦭🦒🧸 Come join the Vertebrate Unit at @nhmdk.bsky.social—a fantastic team in the heart of Denmark's beautiful capital! Amazing collections, incredible history. Please share widely! 🧪🏛️ candidate.hr-manager.net/ApplicationI...
candidate.hr-manager.net
Tenure Track Assistant Professor or Associate Professor and Curator of Mammals
Tenure Track Assistant Professor / Associate Professor, and Curator of Mammals at Natural History Museum Denmark The Natural History Museum Denmark wishes to ap
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Justus Kebschull @justuskebschull.bsky.social · 21/09/2026
NEW PREPRINT! An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
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EMBL @embl.org · 21/09/2026
There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 21/09/2026
Must admit, ever since I was a kid, I’ve dreamt of seeing microscopy images of #protists in @lemonde.fr Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹 One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
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paveltomancak.bsky.social @paveltomancak.bsky.social · 20/09/2026
21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk! marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
marie-sklodowska-curie-actions.ec.europa.eu
MSCA Postdoctoral Fellowships 2026 receives record number of applications
The 2026 call has attracted considerable interest from the research community with 21,627 applications submitted.
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📑 EvoDevo Papers @evodevo-papers.bsky.social · 19/09/2026
Mechanisms of Phenotypic Evolution from Molecules to Organisms: Integrating Evolutionary Biochemistry and Evolutionary Developmental Biology pubmed.ncbi.nlm.nih.gov/42751651 #EvoDevo
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EMBL @embl.org · 17/09/2026
Are you a senior scientist looking to expand your scientific horizons through a sabbatical? 🔬 Then the EMBL Sabbatical Programme is a great opportunity for you! You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months. 🔗Apply here: bit.ly/sabbatical26
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Merlin Lange @merlinlange.bsky.social · 15/09/2026
🔬🧪 We're hiring postdocs&engineers at Institut de la Vision in AMAZING Paris 🇫🇷!! Join a dynamic team working at the nexus of retina developmental biology, spatial omics & advanced imaging Ambitious science in a supportive & young inclusive team 🚀 DM me for more info & please share 🙏 #academicsky
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Anil Seth @anilseth.bsky.social · 16/09/2026
1/6 An extraordinary @nature.com paper has just landed from the lab of @sergiuppasca.bsky.social. They found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells.
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Podcast Science @podcastscience.fm · 31/08/2026
C'est officiel ! 🥳 #Podcast #Science revient en public ! Vous pouvez réservez votre entrée gratuite pour les DEUX prochaines Radio Dessinées du 3 et 4 octobre par ici : www.podcastscience.fm/3-4-octobre-... Des événements organisés par Claire 🥰 Des affiches réalisées par @xapuyo.bsky.social 😻
Affiche de la Radio-Dessiné du Samedi 3 octobre 13h au Palais de la Découverte (17 avenue du Général Eisenhower, Paris 8ème). Le dessin illustre une scientifique en train de dessiner sur un tableau rempli de dessins et formules mathématiques, devant un public nombreux. Un petit mouton l'accompagne sur l'estrade. L'émission est en effet intitulée : "Écoute-moi un mouton"Affiche de la Radio-Dessiné du Dimanche 4 octobre 14h30 au Palais de la Découverte (17 avenue du Général Eisenhower, Paris 8ème). Le dessin illustre un scientifique en train de lécher ou goûter un caillou avec sa langue. Au second plan, un cuisinier assiste tristement à la scène, portant dans ses mains une assiette remplie d'un délicieux plat. L'émission est intitulée : "Le Palais a du goût"
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Pierre Kerner @ssaft.com · 14/09/2026
À NE PAS LOUPER !!!! Pour vous inscrire : --> Écoute moi un mouton (Samedi 3/10 13h) my.weezevent.com/radio-dessin... --> Le Palais a du goût (Dimanche 4/10 14h30) my.weezevent.com/radio-dessin...
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Guillaume Houée 🦷🔬 @guillaumehouee.bsky.social · 05/08/2026
Excited to share our first evo-devo modeling study exploring the developmental origins of the evolutionary transition from dentine–enameloid to dentine–enamel in vertebrates! 🦷 onlinelibrary.wiley.com/doi/10.1111/...
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Cristian Gutierrez-Ibañez @gallinaciega.bsky.social · 09/09/2026
Beautiful new publication by my dear friends João F. Botelho and Macarena Faunes, about development of interdigital membranes in ducks royalsocietypublishing.org/rsos/article...
Microscope images of developing duck feet showing the development of interdigital membranes
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Royal Society Publishing @royalsocietypublishing.org · 09/09/2026
Ambergris, a rare waxy substance produced by sperm #whales, is highly valued for its fragrance but can be difficult to authenticate when found washed ashore. This #RSOS study combined DNA metabarcoding with chemical profiling to improve identification of ambergris specimens: doi.org/10.1098/rsos...
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Nature Communications @natcomms.nature.com · 04/09/2026
This study shows that reliable estimates of trend direction and magnitude require high resolution time series, whereas low-resolution data often capture only direction. www.nature.com/articles/s41...
nature.com
Robust estimates of biodiversity change require high-resolution time series - Nature Communications
Temporal data limitations can bias estimates of biodiversity change needed to address biodiversity loss. This study shows that reliable estimates of trend direction and magnitude require high resoluti...
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Thibaut Brunet @thibautbrunet.bsky.social · 02/09/2026
🚨 New preprint alert! 🚨 Choanoflagellates reorganize their global cytoskeletal architecture within seconds to explore confined microspaces. This is the main PhD work of the amazing @maitefreired.bsky.social www.biorxiv.org/content/10.6... A tread 🧵⬇️
biorxiv.org
Rapid repurposing of microvillar content drives a flagellate-to-amoeboid switch in the closest relative of animals
Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...
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Genome Biology and Evolution @genomebiolevol.bsky.social · 04/09/2026
Kim et al. investigate the evolutionary conservation of molting gene expression across five representative pancrustaceans, showing that some genes active in molting are shared between these species, while most are different. 🔗 academic.oup.com/gbe/article/... #societyjournal #genome #evolution
GBE | Molting in Pancrustacea Is Characterized by Both Deeply Conserved and Recently Evolved Gene Modules

Photo of a molting Scylla paramamosain taken from Figure 1 of Qiao et al 2022 (https://doi.org/10.3389/fmars.2022.971648) used under the Creative Commons Attribution License (CC BY 4.0).
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Marc Robinson-Rechavi @marcrr.ecoevo.social.ap.brid.gy · 04/09/2026
The main #ECCB2026 conference may be over, but today lots of great people are meeting to discuss single-cell standards and collaborations: Single-cell and spatial data FAIRification, community standards and training organised by @fbastian @SIB & @elixir_europe […]
ecoevo.social
Original post on ecoevo.social
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Development @dev-journal.bsky.social · 04/09/2026
The role of geometry in morphogenesis Read this Review from our special issue #DevSIextracellular by Ryan Harrison, Olivier Hamant and @timesaunders.bsky.social. journals.biologists.com/dev/article/...
Role of geometry in shaping tissues. Multiple factors, including cell shape (top left), boundary constraints (top right), topological inputs (bottom left) including from different cell alignment defects (±1/2) and biophysical factors (bottom right) impact how the final tissue form emerges (centre). Centre shows images of a 48 h neuruloid (left; magenta, DAPI; green, actin) and a young Arabidopsis flower (right) treated with oryzalin (depolymerised microtubules) thus showing isotropic growth, but no defect in patterning (organs are still initiated in the right position).
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Thiago Carvalho @cyrilpedia.bsky.social · 01/09/2026
'Transcript variance is several-fold larger than protein variance, reflecting transcriptional bursting and mRNA sampling noise. The proteome is thus the stable, low-noise definition of cell state, while the transcriptome marks cellular transitions'
biorxiv.org
In the same cell, the proteome defines cellular state and the transcriptome marks transitions
Bulk transcriptome and proteome correlate only modestly, but this has not been investigated in the same cell or across cell-state changes. Here we introduce a scalable technology that quantifies thous...
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MEPGT @mepgt.bsky.social · 30/08/2026
Very important paper by @phylogenetrips.bsky.social "Genes and sites under adaptation at the phylogenetic scale also exhibit adaptation at the population-genetic scale" | PNAS www.pnas.org/doi/10.1073/...
pnas.org
Genes and sites under adaptation at the phylogenetic scale also exhibit adaptation at the population-genetic scale | PNAS
Adaptation in protein-coding sequences can be detected from multiple sequence alignments across species or alternatively by leveraging polymorphism...
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MadScientist @mads100tist.bsky.social · 29/08/2026
Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)
biorxiv.org
FOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopy
Understanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar...
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The Company of Biologists @biologists.bsky.social · 28/08/2026
Thank you Ophir Klein @ophirklein.bsky.social for sharing your experience of #OA publishing @dev-journal.bsky.social via our #ReadAndPublish agreement with University of California – San Francisco @ucsflibrary.bsky.social Read Ophir’s paper: doi.org/10.1242/dev....
Publishing our work Open Access in Development allows our article to be immediately accessible to the developmental biology community and beyond; we hope our findings will be useful to scientists across several fields, so the broad and free access is extremely valuable.
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Libération @liberation.fr · 27/08/2026
La science française en décrochage : «Les faits sont là, l’érosion est bien réelle» ➡️ En savoir plus : l.liberation.fr/BtT
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Z. Jack Tseng @tsengzj.bsky.social · 16/07/2026
Our newest paper on mammalian dental evolution, out today as the cover article in @science.org, lead by @narimanechatar.bsky.social with a team of fantastic early career scientists!!! 🎉🥳 “Performance trade-offs define a fundamental dental dichotomy in mammals” www.science.org/doi/10.1126/...
Cover image of Science Magazine, with images of carnivore jaws and teeth on black background.
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Tony Gamble @tonygamble.eurosky.social · 27/08/2026
New collaborative paper from the lab on gecko sex chromosome and genome evolution! 🧪🦎 www.science.org/doi/10.1126/...
science.org
Genomic predisposition is associated with the direction of sex chromosome evolution
Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 ge...
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James Briscoe @jamesbriscoe.bsky.social · 27/08/2026
Our latest: We develop a dynamical landscape modelling framework based on time resolved single-cell data Applied to neural tube fate decisions it shows cell fate decisions as flip bifurcations, a circular topology & it predicts unseen signalling regimes @plosbiology.org doi.org/10.1371/jour...
doi.org
Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data
Applying dynamical systems theory to single-cell data can provide a detailed picture of the cellular states observed during cell fate decisions. This study presents a dynamic landscape analysis (DLA) ...
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