Reposted by Melina A. AgostoBWJones @bwjones.bsky.social · 28/08/2026You can rarely predict what will be a groundbreaking discovery. Most big advancements (and Nobel Prizes) are awarded for basic science, exploratory research. Not translational research. In fact, not even hypothesis driven research in many cases. What works is sustained investment in science. 1133
Reposted by Melina A. Agostocallista yee @csybio.bsky.social · 06/08/2026hiiii everyone! my department @zoology.ubc.ca is hiring an assistant professor in cell and developmental biology! deadline is october 1! academicjobsonline.org/ajo/jobs/32408 // please share!!!!!academicjobsonline.orgUniversity of British Columbia, Department of Zoology Job #AJO32408, Assistant Professor in Cell and Developmental Biology, Department of Zoology, University of British Columbia, Vancouver, British Columbia, CA 16598
Reposted by Melina A. AgostoRan Blekhman @blekhman.bsky.social · 09/08/2026Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9zv3rj... 3222232
Melina A. Agosto @agostolab.bsky.social · 29/07/2026Mini-reunion #2! Former Agosto lab MSc student (and my first graduate!) Andrew Rideout stopped by to visit. 021
Melina A. Agosto @agostolab.bsky.social · 15/07/2026Agosto lab mini-reunion! Current student Robyn McGowan and former student Jaeeun Lee @jaeeunlee.bsky.social at the RRSV/VSRN Restauration de la Vision summer school: 030
Melina A. Agosto @agostolab.bsky.social · 29/06/2026Finally found some time to make a website of sorts. Better (five years) late than never!agostolab.github.ioWelcome to the Agosto labAgosto Lab site 171
Melina A. Agosto @agostolab.bsky.social · 06/06/2026This is very blatant, but is it really surprising? Haven't we always known that antibody "validation" images on company websites are not trustworthy? 120
Reposted by Melina A. AgostoScience Magazine @science.org · 20/05/2026Smell receptor cells in the nose have long been thought of as a chaotic bunch, lacking the spatial organization seen in other sensory systems. But the first comprehensive map of a mouse’s roughly 1100 olfactory receptors overturns that notion. scim.ag/3PzTzqjscim.agUnprecedented map of smell receptors finds order in a mouse’s noseDetailed genomic studies reveal olfactory cells have precise spatial organization 0407
Reposted by Melina A. AgostoUniversity of Pittsburgh Ophthalmology Department @pittophthalmology.bsky.social · 26/02/2026From photoreceptors to visual processing — #Webvision is your open-access deep dive into how we see. Now hosted at our Department, continuing its mission to make vision science accessible to all. Start exploring → www.webvision.pitt.edu #Ophthalmology #Neuroscience 12913
Reposted by Melina A. AgostoNature Astronomy @natastron.nature.com · 16/03/2026Samples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T, U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth. dlvr.it/TRWtVp ☄️dlvr.itA complete set of canonical nucleobases in the carbonaceous asteroid (162173) Ryugu - Nature AstronomySamples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T and U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth. 215177
Reposted by Melina A. AgostoScience Magazine @science.org · 27/02/2026What do you get when #NationalProteinDay and #NationalPokémonDay meet? Pikachurin. ⚡ A 2023 #ScienceSignaling study solved the structure of this extracellular protein that plays an essential role in vision. Learn more: scim.ag/4s82e0N scim.agStructure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179The structure of the orphan GPCR GPR179 bound to the extracellular matrix component pikachurin is solved. 04012
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 17/02/2026New and competitive renewal awards. The number of awards is 569 compared with more than 2200 through the same date in earlier fiscal years. All ICs have now made awards except for NIAAA, NCCIH, NLM, FIC, and OD. NEI (Eye Institute) made its first award during the new period. 3/4 63243
Reposted by Melina A. AgostoAndy Moore @aaandmoore.bsky.social · 05/02/2026An intracellular meteor shower. EB3 comets tracking growing microtubule plus-ends in a cultured cell. 551688245
Melina A. Agosto @agostolab.bsky.social · 31/12/2025Our latest paper is out! It's led by my first MSc graduate, Andrew Rideout, who did a terrific job with this project. We report some fun and confusing results about mGluR6 trafficking. www.sciencedirect.com/science/arti... 284
Reposted by Melina A. AgostoAngelo Iulianella @aineurolab.bsky.social · 19/12/2025As 2025 comes to a close, my university (Dalhousie U in Halifax, Canada) is recruiting faculty, including outstanding early career researchers, and Canada Research Chairs. Applications are due January 19 2026 (was just notified today!). Please repost.dal.caDalhousie University is recruiting up to 30 tenure and tenure-track faculty positionsBacked by the Government of Canada’s $1.7 billion Global Impact+ Research Talent Initiative, Dalhousie University is undertaking one of the most ambitious research-leader recruitment efforts in its hi... 42332
Reposted by Melina A. AgostoNeil deGrasse Tyson @neildegrassetyson.com · 25/11/2025Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine. If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again. #sciencematters 8834841017
Reposted by Melina A. AgostoMiriam B. Goodman, PhD @wormsense.bsky.social · 24/11/2025Application review launches on December 1, 2025. We want to read *your* application outlining a vision for a research program deciphering how membrane proteins collaborate to enable cell function, their biosynthesis, and the biophysics and structure of how membrane proteins change shape. 179
Reposted by Melina A. AgostoAngelo Iulianella @aineurolab.bsky.social · 20/11/2025Dear #Neuroscience researchers, I am Guest Editing an issue in @devdynamics.bsky.social on NEURAL MIGRATION. Due date: March 31, 2026. Great opportunity to showcase your findings on neural migration. #DevBio Please reskeet 🙏 anatomypubs.onlinelibrary.wiley.com/journal/1097...anatomypubs.onlinelibrary.wiley.comDevelopmental Dynamics<em>Developmental Dynamics</em> is a developmental biology journal publishing novel discoveries that advance our understanding in development, morphology, evolution, and disease. 11311
Reposted by Melina A. AgostoPranav Seth @thebuddhabird93.bsky.social · 14/11/2025Ending my #FluorescenceFriday with this beautiful avian retina image depicting the beautiful stratification in the avian eyes. This is where complexity meets art. #retina #avian #bird #plexiformlayer 37012
Melina A. Agosto @agostolab.bsky.social · 30/09/2025We replaced the gaskets on the gel pouring rigs with foam weatherstrip a few months ago. No leaks yet! 040
Reposted by Melina A. AgostoAnita Devineni @anitadevineni.bsky.social · 30/09/2025My department at Emory is a hiring a tenure-track neuroscientist! Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply! apply.interfolio.com/174371apply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 1135104
Reposted by Melina A. AgostoDr. Nikki Crowley @nicoleacrowley.bsky.social · 18/09/2025WE ARE... hiring! Penn State Biology & the Huck Institutes of the Life Sciences is recruiting a tenure track or tenured neurobiologist (Assistant or Associate Professor rank), and the committee is open to a broad scope of scientific questions. psu.wd1.myworkdayjobs.com/PSU_Academic... 12719
Reposted by Melina A. AgostoPaul & Virginie - Centriole Lab @centriolelab.bsky.social · 15/09/2025Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network. 04248
Melina A. Agosto @agostolab.bsky.social · 11/09/2025New paper! Kudos to first author Jaeeun Lee, who is a fantastic and hard working student. We showed that at photoreceptor presynapses, ELFN1 enrichment depends on postsynaptic mGluR6. www.jneurosci.org/content/earl... 2156
Melina A. Agosto @agostolab.bsky.social · 30/08/2025The mysterious non-PSD localization of PSD95 🟣 in the retina outer plexiform layer... co-stained for postsynaptic TRPM1 🟢 #FluorescenceFriday 0122
Reposted by Melina A. AgostoGraham Dellaire @docdellaire.bsky.social · 27/08/2025Dalhousie University invites applications for the position of Dean, Faculty of Medicine. This is a pivotal leadership opportunity to shape the future of medical education, research, and healthcare across the Maritime provinces in Canada. 5 yr renewable appointment dal.peopleadmin.ca/postings/19319dal.peopleadmin.caDean of MedicineDalhousie University invites applications for the position of Dean, Faculty of Medicine. This is a pivotal leadership opportunity to shape the future of medical education, research, and healthcare acr... 165
Reposted by Melina A. AgostoMathew Kiang @mathewkiang.com · 25/06/2025Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...ki.seCall for 20 Assistant Professor positionsKarolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce... 1278277
Reposted by Melina A. AgostoJan-Willem Veening @veeninglab.com · 10/06/2025New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...wwwfbm.unil.chDMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM 0110161
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 09/06/2025I updated my funding curves last night. Here are the results for new and competitive renewal grants. The rate of investment has dropped substantially. This is apparently due to a requirement for DOGE review. I am calling this effect the "Downward DOGE" 1/2 49064
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 07/06/2025Funding freeze at Northwestern from Emma Mairson at grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis. Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long. 2224105
Reposted by Melina A. AgostoDavid Solecki @so-lets-kilab70.bsky.social · 26/05/2025Wonder doesn’t flinch. It’s our compass pulling us toward curiosity, creativity It reminds us: #science & #discovery are good. Here’s a moment that stirred mine: a new PI(3,4)P₂ probe illuminating the cell membrane & endosomes. Marvel with me. Captured on #FluorescenceFriday for #MicroscopyMonday 69218
Melina A. Agosto @agostolab.bsky.social · 03/05/2025An elegant ON bipolar cell expressing ER marker mEmerald-Sec61 🟦 and co-stained with mGluR6 antibody 🟥. #FluorescenceFriday More info in this old paper: www.eneuro.org/content/5/3/... 0204
Reposted by Melina A. AgostoAnalytical and Quantitative Light Microscopy Course @aqlm.bsky.social · 01/05/2025Have you ever seen the black box that is the inside of a microscope objective? Today Dr. Stephen Ross of Nikon gave a fascinating lecture on what goes into the design and manufacturing of an objective. 14912
Reposted by Melina A. AgostoJim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 04/04/2025www.nature.com/naturecareer... UBC LSI Job!!nature.comAssistant Professor (tenure track) – Chromatin, Epigenetics - Vancouver, British Columbia (CA) job with The University of British Columbia (UBC) | 12837841Assistant Professor (tenure track) - Chromatin Regulation, Genetic Regulatory Mechanisms, Epigenetics, Epigenomics 03136
Reposted by Melina A. AgostoPeri Kurshan @pkurshan.bsky.social · 26/03/2025FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!faculty-einstein.icims.com Albert Einstein College of Medicine | Medical Education | Biomedical Research 17167
Reposted by Melina A. AgostoNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 15/03/2025as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech bsky.app/profile/need... 3328115
Reposted by Melina A. AgostoDr. David Miller 🏳️🌈 @davidimiller.bsky.social · 03/03/2025🧪🚨 NSF's Directorate for STEM Education (EDU) has halted making nearly all new awards since inauguration day. Among *many* other things, EDU runs the Graduate Research Fellowship Program (GRFP). We need to protect the education & training of the next gen of scientists #StandUpForScience Thread👇🧵 2232161
Reposted by Melina A. AgostoDr. Brittany J. Carr @drbjcarr.bsky.social · 06/03/2025An excellent opportunity! And I'm not just saying that because I'll be teaching an imaging and comparative retinal anatomy workshop during this course 😁 👀 Financial aid is available! 083
Melina A. Agosto @agostolab.bsky.social · 05/03/2025Submitted a new CIHR grant today. I don't suppose it will be funded, but I'm grateful to at least have a functional federal agency to submit it to. Also - sunset in the retina lab kitchen: 160
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 01/03/2025Extending my grant update this morning. Here are data limited to new and competitive renewal applications. The Pause is dead, Long live the Pause... 12292162
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 24/02/2025Some good-ish news from NIH “Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again” As far as I know, the timing for this is not clear, but I will be checking the Federal Register.media.tenor.coma man in a red suit and tie is holding a piece of paper that says breaking news on itALT: a man in a red suit and tie is holding a piece of paper that says breaking news on it 17392151
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 22/02/2025Guardian article on NIH www.theguardian.com/us-news/2025...theguardian.comCritics say Trump’s executive orders to reshape the NIH ‘will kill’ AmericansExecutive orders’ impact on premier medical research agency has resulted in delayed projects and frozen funding 38444
Melina A. Agosto @agostolab.bsky.social · 23/02/2025Study sections scheduled for this past week that were canceled: 023
Reposted by Melina A. AgostoBWJones @bwjones.bsky.social · 21/02/2025We all owe @jeremymberg.bsky.social a debt of gratitude for his work in clarifying, connecting, and advocating for science in this chaotic time. 🙏🏼 220135
Reposted by Melina A. AgostoJonathan Lambert @jonlambert.bsky.social · 18/02/2025NEW: NSF confirmed that they fired 168 employees today, out of their staff of ~1,500 feds. This includes some people who'd finished their 1-year probationary periods, which were extended to 2-years last month without explanation. More to come. 29904506
Reposted by Melina A. AgostoScience Magazine @science.org · 14/02/2025President Donald Trump’s administration today moved to fire 5200 workers at the Department of Health and Human Services, using supervisors across the vast agency to warn probationary employees that they would soon receive termination notices. scim.ag/4jYmcYAscim.ag‘Wrecking ball’: RFK Jr. moves to fire thousands of health agency employeesSupervisors deliver bad news across NIH, CDC 511158
Reposted by Melina A. AgostoJeremy Berg @jeremymberg.bsky.social · 16/02/2025The damage today (actually yesterday) to the intramural program appears to especially bad. It also appears (although I need more confirmation) that most or all of the tenure track investigators in their first 2 years in several, and perhaps all, institutes were terminated. 7/n 316755