iiinova — where your digital self keeps evolving

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SNP2Prot @snp2prot.bsky.social · 17/09/2026

#SNP2Prot speaker Marcel Quint kicks off this year‘s retreat that is taking place at @leibnizipk.bsky.social we look forward to reconnecting and discussing the progress made in the last two years 🌱

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 13/09/2026

Fold Spacer lets you fly through protein structures (Weekend project #2). It’s my first game: I originally set out to build a racer with structures as the tracks, but was a little too crazy. So it became this instead. You can upload your own structures. 🌐 martin-steinegger.github.io/Fold-Spacer/

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Mariana Schuster @marischuster.bsky.social · 07/09/2026

I'm excited to share that my newly funded #ERCStG FRONTERA is recruiting two postdoctoral researchers at @ipbhalle.bsky.social 🌱🔬 If you are passionate about plant immunity, proteolysis, membrane proteins, or proteomics, I'd love to hear from you. 🧵 Please RT/share!

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Mariana Schuster @marischuster.bsky.social · 03/09/2026

Thrilled to have the opportunity to investigate the role of membrane protein proteolysis in plant immunity through the ERC Starting Grant FRONTERA! A heartfelt thank you to my mentors, friends, and family whose support, encouragement, and guidance made this possible. #ERCStG @erc.europa.eu

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Thiago Carvalho @cyrilpedia.bsky.social · 25/08/2026

'Critical feedback is necessary, but it must be constructive. Point out weaknesses clearly, suggest ways to address them, and acknowledge strengths. A balanced review provides both encouragement and actionable guidance.' journals.plos.org/ploscompbiol...

journals.plos.org

Ten simple rules for writing a peer review

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Sholto David @sholtodavid.bsky.social · 25/08/2026

Today I'm posting a new blog! Nearly two hundred papers have muddled the names for different proteins and recorded using the wrong antibody for a range of experiments. This time it's PERK vs. p-ERK. Including researchers from Harvard, the Mayo Clinic, and more. sholto.substack.com/p/perk-vs-p-...

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Mariana Schuster @marischuster.bsky.social · 16/08/2026

Celebrating the completion of our DAAD RISE internship! @aciattoni.bsky.social conceived, funded and managed the project while providing excellent mentorship. Nilay brought curiosity, dedication and great work to the lab. Congratulations to both, and best wishes to Nilay! 🌿🔬 #DAADRISE #SNP2Prot

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Karen Uchida @karenuchida.bsky.social · 15/07/2026

It's back live! Check out my week at TSL 🌱

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yuxuan-xi.bsky.social @yuxuan-xi.bsky.social · 11/07/2026

Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...

doi.org

Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.

The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...

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The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 06/07/2026

Continuing the hidden curriculum of academic science thread. . . There are often many "right" ways to do the same overall lab experiment & different labs often do things in different ways (different protocols, equipment, buffers, etc.) based on what they have &/or know. youtu.be/bMQwIp13cas

youtu.be

There are often many "right" ways to do the same overall lab experiment

YouTube video by the bumbling biochemist

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Alexander Ciattoni @aciattoni.bsky.social · 30/06/2026

I thought this was only possible in science fiction! In the bottom row you can see the reconstruction of what the brain sees, using the activity of neurons.

Fig.2: image reconstruction of video from mice.
The figure compares three frames of ground truth (top) with corresponding reconstructed frames (bottom), showing a mouse-like subject moving across a grayscale scene; the reconstructions are labeled 1, 2, and 3 under the bottom panels.

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Kiran Raj 🌱 @kiranrajrki.bsky.social · 22/06/2026

KKRSU-001: The Missing Inventory Manager Inspired by the recent study @science.org Meet Rooty, Chef Chloro, Inspy, and Vivi, the first residents of the KRSU universe. Based on the work from @martinaried.bsky.social and @gabrielschaaf.bsky.social The science is real. The story is fiction🌱:-)

KRSU-001: The Missing Inventory Manager. Cartoon-style scientific illustration explaining phosphate signalling in plants. Rooty, a worried root character wearing blue overalls, frantically searches the soil for phosphate. Chef Chloro, a leaf chef, works in a kitchen above ground and asks whether phosphate is running out. Inspy, a small messenger character representing InsP8, reports that no inventory updates have been received. The office of Vivi (VIH2), the inventory manager responsible for phosphate-status communication, is empty and marked "Out of Office." The card illustrates the concept that loss of VIH2 disrupts InsP8 signalling, causing the plant to behave as though phosphate is scarce even when phosphate is available. The image combines fictional characters and storytelling with real plant biology inspired by a Science Advances study.

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Stefan A. Rensing @rensingstefan.bsky.social · 18/06/2026

Updated @theplantjournal.bsky.social guidelines: avoid the use of terms such as “basal”, “early diverging lineage”, “primitive”, “ancestral plant”, “lower and higher plants” [..] recommends the use of specific terms such as “bryophytes”, “vascular plants” [..] onlinelibrary.wiley.com/page/journal...

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Ohad Roth @ohadroth.bsky.social · 16/06/2026

How do pathogens disarm plant immunity? We discovered a widespread strategy used by plant bacterial pathogens: they directly cleave a conserved immune signaling molecule produced by plant immune receptors. www.biorxiv.org/content/10.6...

biorxiv.org

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Plant Science Spotlight @plant-sci.bsky.social · 13/06/2026

🌱🧬Pathogens manipulate the apoplast by controlling pH, water & nutrients. Plants fight back with oxidative bursts, toxins & hydrolases. Adapted pathogens disarm these defenses & hide from detection Molecular arms race outside the cell @annualreviews.bsky.social www.annualreviews.org/content/jour...

annualreviews.org

Extracellular Antagonists: Offense and Counter-Defense in the Apoplast

Extracellular interactions are pivotal in the plant–pathogen arms race. Fungal, bacterial, and oomycete pathogens manipulate the apoplast to control pH, water soaking, sugar levels, and nutrient avail...

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The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 11/06/2026

Who should be crowned the crystal caption champion????!!! It's up to you! Thanks for helping crown the champ and keep crystallography cool! youtu.be/7ggSKn_itGk Link to vote (please do so by the Monday June 15): qrpoll.com/Rwf8Yb

youtu.be

Who should be crowned the crystal caption champion????!!! It's up to you!

YouTube video by the bumbling biochemist

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Carolin Delker @carolindelker.bsky.social · 08/06/2026

Hiring: Junior Group Leader (f) in Protein Science — CRC 1664 SNP2Prot, MLU Halle. Lead your own group + budget, funded PhD, world-class protein-structure facilities. 5 yrs, E14. Apply by 7 July 2026. snp2prot.uni-halle.de #ProteinScience #SNP2Prot #AcademicJobs

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BWJones @bwjones.bsky.social · 05/06/2026

Doing a linear stretch on these images shows how dramatic the "edits" were, revealing the deception in clear terms. This should be a complete scandal for Thermo Fisher and more people in the biosciences should be talking about it.

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Alexander Ciattoni @aciattoni.bsky.social · 04/06/2026

What an inspiring conference! Grateful to have been part of it and pleased my talk resonated with people. Big thanks to the organizers and everyone I met at the #ICPP2026

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Mariana Schuster @marischuster.bsky.social · 02/06/2026

Now on: our own Christian Wall presenting the nepenthesin work (published) he made with @sinzandrea.bsky.social prior joining #SNP2Prot @unihalle.bsky.social #IPP2026

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Mariana Schuster @marischuster.bsky.social · 31/05/2026

#IPPC2026 starts now!! I am thrilled to be here with @adithya1972.bsky.social @aciattoni.bsky.social and Christian Wall for four days of total immersion on the world of plant proteases!

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Alexander Ciattoni @aciattoni.bsky.social · 29/04/2026

Just tried this today, it works really well! Thanks for the lab hack 🔧🧪

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Alejandro Montenegro @aemonten.bsky.social · 25/04/2026

Create paper and figures with AI. Sell authorship. Submit to a journal with a bribed editor. Fake peer review reports. Collect incentive money from institution for publishing. Have Chatbots learn from that paper. Repeat. Maybe, just maybe, the incentive shouldn't just be "to publish".

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Mariana Schuster @marischuster.bsky.social · 23/04/2026

If you pay attention, you will most likely find a #protease story in each conference 🙃. This time Pierre Stallforth mentions their recently described and intriguing “Lips” At the IPB Symposium. Have a look to their paper: pubs.acs.org/doi/10.1021/...

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Mariana Schuster @marischuster.bsky.social · 22/04/2026

It is that time of the year when the @ipbhalle.bsky.social puts together an excellent lineup for speakers for our Plant Biochemistry Symposium. This time the symposium reflects Steffen Abel’s scientific interests as we celebrate his time at the IPB

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The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 15/04/2026

When's it good to feel blue? When you're running a blue native PAGE! youtu.be/T0eYmTDX1bc

youtu.be

Blue Native PAGE

YouTube video by the bumbling biochemist

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IPB Halle @ipbhalle.bsky.social · 14/04/2026

🌱 #PSSC2026 is coming to IPB Halle (10-12 June 2026). Organized by our doctoral representatives, the student conference offers great talks, poster sessions, workshops & keynote lectures by invited international plant scientists. Info & registration: eveeno.com/pssc26 #PhDnetwork #PlantSci #PlantECRs

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Elwira Smakowska-Luzan @elwirasmakowska.bsky.social · 31/03/2026

Preprint alert! I am extremely happy to finally (!) share our work on the redox-dependent regulation of the CRKs in plants! We integrated high-throughput interactomics, redox proteomics, structural modelling, and genetics to map a ROS-dependent CRK interaction landscape in Arabidopsis.

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SNP2Prot @snp2prot.bsky.social · 28/03/2026

Latest publication from SNP2Prot colleagues C. Wall and A. Sinz reveals that the Nepenthesin protease, isolated from 𝘕𝘦𝘱𝘦𝘯𝘵𝘩𝘦𝘴 sp., carries superior proteolytic activity towards IDPs. Kudos to the team 🎉 doi.org/10.1002/cbic... #MassSpec #Protease #IDPs #Proteomics @sinzandrea.bsky.social

doi.org

A Native Nepenthesin Reactor for Improved Proteolytic Digestion of Intrinsically Disordered Proteins in Proteomics Workflows

A workflow is presented for the extraction and purification of native nepenthesin (NEP-NAT) from Nepenthes species, followed by the enzyme's immobilization on POROS-AL chromatographic material. The N...

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Moi Expósito-Alonso (MOILAB) @mexpositoalonso.bsky.social · 26/03/2026

Our new experimental evolution study across 30+ locations using the plant Arabidopsis thaliana —— we direct "see" adaptation and extinction to different climates at the genetic as it happens! Read it in Science dx.doi.org/10.1126/scie... @ucberkeleyofficial.bsky.social @hhmi-science.bsky.social

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Mary Williams @PlantTeaching @plantteaching.bsky.social · 25/03/2026

"A plant-based diet requires far fewer resources than a standard western diet ... Just as we make ourselves more energy-secure by switching from fossil fuels to renewables, we make ourselves more food-secure by switching from animals to plants." Nice analogy! www.theguardian.com/commentisfre...

theguardian.com

We’re letting big corporations gamble with our lives. Act now, or the food could run out | George Monbiot

The fragility of the global food system fills me with dread – and the war with Iran has exposed just how close to collapse it is, says Guardian columnist George Monbiot

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DOMPS @domps-ufr.bsky.social · 25/03/2026

An essential part of our symposium is the Poster Speed-Dating, where our researchers (bachelor/master/PhD students) present their latest results in 5 minutes (+2 minutes Q&A). A fast and effective way to catch up on the newest research across the DOMPS community.

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IMPRS for Living Matter @imprs-lm.bsky.social · 23/03/2026

Excited to decode the intricate language of ubiquitin chains and unravel their role in protein degradation? 🧬🔬 👉 APPLY NOW to join the lab of Dr. Leo Kiss @leokiss.bsky.social @imprs-lm.bsky.social. #CellularBiochemistry #Ubiquitin #Proteostasis #ProteinDegradation

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SNP2Prot @snp2prot.bsky.social · 23/03/2026

Day one of our spring retreat. The poster session is in full swing! @unihalle.bsky.social

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Daniil Litvinov @daniil-litvinov.bsky.social · 19/03/2026

I'm excited to share *Stoic*, a method for fast and accurate protein complex stoichiometry prediction directly from sequence. Preprint: www.biorxiv.org/content/10.6... 🧵👇(1/10)

biorxiv.org

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German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 18/03/2026

Congratulations! 👏 Marco @trujillolab.bsky.social receives this year‘s #SciComm Award of our @molplantsci.bsky.social for his long-term, consistent + clear presentation in social media. Read more about the award and his tips for #ECRs www.pflanzen-molekularbiologie.de/en/sci-comm#... #MBP2026

pflanzen-molekularbiologie.de

Our SciComm Award for excellent science communication

Our SciComm Award and other news from science communication

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Marco Trujillo @trujillolab.bsky.social · 17/03/2026

Our very own Cansu Dilege on: How are E2 enzymes regulated? -> Yes, kinases are involved (several)! #MBP2026 #ecr #ubiquitin #UniHamburg

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Sophie Zoe Farkas @sophiezoe.bsky.social · 14/03/2026

You can read our summary with @prshanth.bsky.social about the mini symposium in the latest #ISRR newsletter. 👇🏼 #PlantScience

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Mariana Schuster @marischuster.bsky.social · 13/03/2026

Registration for the 7th International Plant Protease Conference closes soon (Apr 1st)! If your research touches plant proteases (whether directly or just at the edges), don’t miss this meeting. We’re a small, supportive community and always happy to collaborate! www.plantprotease.org

plantprotease.org

Home | Plant Protease Confe

Home

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Elke Barbez @elkebarbez.bsky.social · 11/03/2026

Want to image apoplastic pH in plants? 🔬 Two new papers from our team offer a full workflow plus open access analysis tools. Congrats to @aroessling.bsky.social, Niklas Mayle and @lguerard.bsky.social Nature Protocols: rdcu.be/e7R2E BMC Methods: lnkd.in/dctpWJ3X Happy Imaging!

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Sebastian S. Cocioba @atinygreencell.bsky.social · 25/02/2026

Secret science isn't science.

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