Reposted by Alexandre SerafimJacqueline Antonovich @jackiantonovich.bsky.social · 12/10/20266 people are no longer with us in PA because of the measles. @bachynski.bsky.social 13515
Reposted by Alexandre SerafimDr. Lawren is Openly Ya Ya @lwpedsmd.blacksky.app · 12/10/2026Measles cases have surpassed 4,000 this year, according to CDC data. In the past week it rose to 4080, the highest since 1991. Measles is a vaccine preventable illness. publications.aap.org/aapnews/news...publications.aap.orgMeasles cases top 4,000; flu increasingThe tally increased by 193 cases over the past week to 4,080, the highest since 1991. 022
Reposted by Alexandre SerafimHealthcare-Global @healthcare-global.bsky.social · 11/10/2026www.nature.com/articles/s41...nature.comThe role of the respiratory microbiome in acute and chronic respiratory diseases - Nature Reviews MicrobiologyIn this Review, Heinzinger, Segal and Dickson summarize recent advances in our understanding of the respiratory microbiome in health, examine how it is altered in acute and chronic respiratory disease... 042
Reposted by Alexandre SerafimBMJ Medicine @bmjmedicine.bsky.social · 11/10/2026A new specialist review by Kendra Gilreath and colleagues summarises the pathogenesis of hypertrophic cardiomyopathy to help clinicians screen, diagnose, and improve the treatment of patients. Read now in BMJ Medicine: bit.ly/4y1o60k #Cardiologybit.lyPathogenesis, screening, and diagnosis of hypertrophic cardiomyopathyHypertrophic cardiomyopathy is a common heritable heart disease. The disease is genetically, anatomically, and clinically heterogeneous. Hypertrophic cardiomyopathy is inherited in an autosomal domina... 021
Reposted by Alexandre SerafimJAMA Ophthalmology @jamaophthalmology.bsky.social · 10/10/2026In 2023, about 1 in 5 people had spending on #CorrectiveLenses, and about half of those purchases were paid entirely out-of-pocket. ja.ma/3VtPc2L 011
Reposted by Alexandre SerafimJocalyn Clark @jocalynclark.bsky.social · 08/10/2026Op-eds from VIP types are tricky for medical journals. You don't often see a president & the WHO head co-authoring a piece in ... the NEJM. But here we have a commentary describing their efforts to coordinate #Hantavirus response & affirming the importance of solidarity and collaboration in health:nejm.orgHantavirus — Lessons Learned about Security and Solidarity | NEJMPedro Sánchez and Tedros Adhanom Ghebreyesus reflect on the management of Andes hantavirus and the way in which careful, coordinated outbreak response can limit risk without undermining dignity. 054
Reposted by Alexandre SerafimThe Lancet Microbe @lancetmicrobe.bsky.social · 08/10/2026New research article Regional expansion and adaptive evolution of multidrug-resistant #Candida tropicalis in China: a retrospective, multicentre, genomic study www.thelancet.com/journals/lan... #IDSky #ClinMicro #MicroSky #MycoSky #AMR #OpenAccess #OA 034
Reposted by Alexandre SerafimNature Reviews Neuroscience @natrevneuro.nature.com · 08/10/2026Sensing the skeleton: sensorineural regulation in bone — a Review by Zhao Li, Manyu Zhu, Neelima Thottappillil, Sowmya Ramesh & Aaron W. James #neuroscience #neuroskyence www.nature.com/articles/s41...nature.comSensing the skeleton: sensorineural regulation in bone - Nature Reviews NeuroscienceThe skeleton is innervated by neurons that convey sensory information to the CNS and release neuroregulatory peptides to influence the bone microenvironment. James and colleagues describe the mechanis... 0104
Reposted by Alexandre SerafimLiz Szabo @lizszabo.bsky.social · 06/10/2026Measles amnesia “is an under appreciated” complication of the disease. What is it? Read my story. 04823
Reposted by Alexandre SerafimSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 06/10/2026Co-occurrence of Heterozygous Variants in PKD1 and ALG9 in a Patient With Early-Onset ESKD: A Case Report - Kidney International Case Reports www.kicasereports.org/article/S311... March issue highlightskicasereports.orgCo-occurrence of Heterozygous Variants in PKD1 and ALG9 in a Patient With Early-Onset ESKD: A Case ReportAutosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder, predominantly caused by pathogenic variants in the PKD1 and PKD2 genes. Variants in other genes, including ALG9, have eme... 042
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 05/10/2026Volatile anesthetic sedation in acute respiratory distress syndrome CCR Journal Watch criticalcarereviews.com/latest-evid… 011
Reposted by Alexandre SerafimProf Gavin Yamey MD MPH @gavinyamey.bsky.social · 05/10/2026Essential, brilliant reporting by @by-cjewett.bsky.social It's TERRIFYING: MAHA folks are INVESTIGATING pediatricians, who are some of the lowest paid docs in the professions, for vaccinating kids It's part of a 20-year anti-vaxx campaign by RFK Jr "that some of his political allies have joined" 34722
Reposted by Alexandre SerafimJack Iwashyna @iwashyna.bsky.social · 05/10/2026"Paired Spo2 measurements differed by ≥ 3% during 33% of monitored time (95% CI, 30%-35%) and by ≥ 5% during 13% of the time (95% CI, 12%-15%). The concordance correlation coefficient was 0.41, indicating poor agreement between paired Spo2 measurements." www.chestcc.org/article/S294...chestcc.orgDiscrepancy Between Peripheral Oxygen Saturation Measurements Obtained Simultaneously From 2 Pulse Oximeters Made by Different Manufacturers in Acutely Ill PatientsAmong adults hospitalized with acute hypoxemia, Spo2 values measured simultaneously by 2 pulse oximeters from different manufacturers differed by a clinically meaningful amount approximately one-third... 363
Reposted by Alexandre SerafimEric Topol @erictopol.bsky.social · 01/10/2026In the new @science.org special issue on women's health, a 5★ review of menopause hormone therapy to promote healthy aging science.org/doi/10.1126/...science.orgReframing menopause and menopause hormone therapy as opportunities for healthy agingMenopause is an important biological transition with up to 72 symptoms that shapes aging trajectories across organs and encompasses ~40% of the female lifespan. Although menopause awareness is increas... 116663
Reposted by Alexandre SerafimNEJM.org @nejm.org · 01/10/2026Duchenne muscular dystrophy, the most common childhood muscular dystrophy, with an estimated prevalence of 1 in 5000 boys 5 to 9 years of age, is a recessive degenerative disorder caused by variants in the dystrophin gene that lead to deficiency of dystrophin. Learn more: nej.md/4h7h0SP 063
Reposted by Alexandre SerafimATS Blue Journal @atsblueeditor.bsky.social · 01/10/2026Editorial: From mechanisms to clinical practice: introduction to an AJRCCM special section on interstitial lung disease #ILD academic.oup.com/ajrccm/artic... @atscommunity.bsky.socialacademic.oup.comFrom mechanisms to clinical practice: introduction to an AJRCCM special section on interstitial lung diseaseThis issue's special section on interstitial lung disease (ILD) spans the translational spectrum of ILD research, encompassing clinical practice guidelines 022
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 30/09/20262026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery CCR Journal Watch criticalcarereviews.com/latest-evid… 022
Reposted by Alexandre SerafimStanford Neurology & Neurological Sciences @stanfordneuro.bsky.social · 27/09/2026Biological age vs chronological age—what the science says. Tony Wyss-Coray, PhD explains that biological age reflects the body’s aging trajectory and functional health—not just calendar years. med.stanford.edu/news/insights/2026…med.stanford.eduBiological age versus chronological age: What the science saysStanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more. 023
Reposted by Alexandre Serafim50501: The People’s Movement ❌👑 @50501movement.bsky.social · 27/09/2026Do you know your voting deadlines? Depending on your state, you may be running out of time to register to vote in the midterm elections. Take 10 minutes today to make sure you’re ready to vote by November 3 & vote early if you’re able. #HandsOffOurVote 8206163
Reposted by Alexandre SerafimAnnals of Emergency Medicine @annalsofem.bsky.social · 25/09/2026Dexmedetomidine may offer a new option for selected adolescents with recurrent severe agitation during prolonged ED psychiatric boarding. This editorial asks the key questions: Is it necessary, feasible, safe, and ethical? Paper 🔗 www.annemergmed.com/article/S019... 022
Reposted by Alexandre SerafimWFPICCS @wfpiccs.bsky.social · 23/09/2026🌏 Sharing ideas, advancing science & turning knowledge into practice that’s what brings Dr Vinay Nadkarni to #WFPICCS26 in Melbourne! 📍 Melbourne | 26–30 September 2026 👉 Explore the program 🔗 wfpiccs2026intensivecareasm.com/program/ #PedsICU @openpediatrics.bsky.social @sapnakmd.bsky.social 011
Reposted by Alexandre SerafimNEJM.org @nejm.org · 23/09/2026In a new NEJM Voices blog post, Don Dizon, MD, argues that artificial intelligence tools used in medicine will never replace clinicians. See why: nej.md/46BpP1a 042
Reposted by Alexandre SerafimSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 19/09/2026Following up on BEST FLUIDS - this RCT of ringers versus D5-NS post transplant with surrogate outcomes www.kireports.org/article/S246... in @kireports.bsky.social A bit more confidence that RL may be ~ plasmalyte? 132
Reposted by Alexandre SerafimRyan Marino, MD @ryanmarino.bsky.social · 19/09/2026Hotter, wetter summers, and milder winters - in addition to a lack of supportive infrastructure to prevent it - have helped dengue spread drastically around the globe in recent years, and into the continental United States. We do not have an approved vaccine for it and it’s difficult to test for.theconversation.comDengue-carrying mosquitoes expand their reach into new territories – including FloridaAs dengue spreads further outside its normal tropical zones, doctors and patients need to know what to watch for. 27619
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 19/09/2026The 2nd trial for CCR Frankfurt is CONFIDENCE To be presented by Frederique Paulus & Siebe Blok Can lung ultrasound-guided fluid removal increase ventilator-free days? Join us 22–23 February, 2027 Registration opens shortly criticalcarereviews.com/meetings/ccr... #CCRFrankfurt 112
Reposted by Alexandre SerafimWFPICCS @wfpiccs.bsky.social · 16/09/2026🌏 Explore the future of intensive care in vibrant #Melbourne at #WFPICCS26! 🎥 Prof @fenellagill.bsky.social shares what awaits 📍26–30 Sept 2026 👉 wfpiccs2026intensivecareasm.com/program/ 🦘Stay longer to discover Melbourne & Victoria! melbournecb.com.au/welcome-to-melbourne #PedsICU #visitmelbourne 011
Reposted by Alexandre SerafimNEJM.org @nejm.org · 16/09/2026For patients with esophageal cancer, 5-year survival has improved in recent decades but rarely exceeds 20%. A new review summarizes risk factors, screening, and treatment for the two main histologic types. Read the full review: nej.md/3Tb2NuX 031
Reposted by Alexandre SerafimRyan Marino, MD @ryanmarino.bsky.social · 15/09/2026All 4 deaths have been in the unvaccinated.cnn.comPennsylvania reports fourth measles-related death, the most in US in decades | CNNPennsylvania has reported a fourth death related to measles, the latest in a growing outbreak that has also sparked ongoing political clashes. 718058
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 15/09/2026Clinical Management of Myocardial Infarction CCR Journal Watch criticalcarereviews.com/latest-evid… 011
Reposted by Alexandre SerafimWFPICCS @wfpiccs.bsky.social · 14/09/2026🎥Our Immediate Past President, Brenda Morrow previews her #WFPICCS26 talks on🌐research capacity & ethical challenges in resource-limited care 📍 Join us in Melbourne from Sep 26-30! ➡️Explore the program here 👉🔗https://wfpiccs2026intensivecareasm.com/program/ #PedsICU #globalhealth 011
Reposted by Alexandre SerafimPapertis @papertis.bsky.social · 12/09/2026Interesting to see a pragmatic trial design tackle a question that's been debated for years. The equipoise here seems genuine—speaks to how much we still don't know about fluid choice despite how fundamental it is to critical care. 011
Reposted by Alexandre SerafimBMJ Medicine @bmjmedicine.bsky.social · 12/09/2026New research from Padmini Selvaganesan and colleagues evaluates the effectiveness of SGLT2 inhibitors in reducing the risk of hospital admission for heart failure and mortality in patients with heart failure with preserved ejection fraction bit.ly/4gQXE30 011
Reposted by Alexandre SerafimIt's ME(Jaime) @exceedhergrasp1.bsky.social · 12/09/2026An article from @iwashyna.bsky.social about witnessing & reacting to misogynoir in an ED setting led me Prof. Koritha Mitchell's ( @profkori.bsky.social ) definition of know-your-place aggression and whewboy: voices.nejm.org/doi/full/10.... 2248
Reposted by Alexandre SerafimThe BMJ @bmj.com · 10/09/2026Nearly a third of the government’s nutrition advisors still have “significant” ties to the food industry including Coca Cola, Sainsbury’s, and Danone, reveals our new investigation. Despite a new code of conduct banning links to the food industry, members with ties are allowed to remain in postbmj.comA third of UK government’s nutrition advisers are still paid by food industry, including Coca-Cola and NestléFinancial conflicts of interest remain rife in the Scientific Advisory Committee on Nutrition (SACN), BMJ analysis reveals. Despite a new code of conduct banning links to the food industry, members wi... 21614
Reposted by Alexandre SerafimBritish Journal of Anaesthesia @bjajournals.bsky.social · 09/09/2026#Correspondence by Raul Bustos et al reporting a #PRIS induced by low dose propofol infusion in an #infant. #Fatty acid oxidation should be checked in children with metabolic symptoms before #sedation. www.bjanaesthesia.org.uk/article/S0… 023
Reposted by Alexandre Serafimhaysamrady @sodatroubles.bsky.social · 09/09/2026Acute glucagon infusion induces natriuresis and diuresis through a direct tubular mechanism involving overlapping receptor pathways #nephsky #nephrology journals.physiology.org/doi/full/10....journals.physiology.orgAcute glucagon infusion induces natriuresis and diuresis through a direct tubular mechanism involving overlapping receptor pathways | American Journal of Physiology-Renal Physiology | American Physiol...It is unclear whether the reported natriuretic and diuretic effects of glucagon are mediated by renal hemodynamic changes or by direct tubular actions within the kidney. We investigated the renal effe... 042
Reposted by Alexandre SerafimEuropean Society of Paediatric and Neonatal Intensive Care @espnic.bsky.social · 09/09/2026The #ESPNIC Journal Club begins TOMORROW! Join us tomorrow at 3 PM to learn more about the Association between Protein Intake and Muscle Wasting in Critically Ill Children with leading experts! Free Registration✅: bit.ly/4zNbbBd 011
Reposted by Alexandre SerafimBMJ Medicine @bmjmedicine.bsky.social · 08/09/2026Deshi Chen and colleagues compare the efficacy and safety of GLP-1 based treatments for weight loss in non-diabetic adults with overweight or obesity, finding weight loss was greater with next generation incretin based treatments than conventional GLP-1 receptor agonists bit.ly/4zPl2X8bit.lyComparative efficacy and safety of glucagon-like peptide 1 based drugs for weight loss in adults with overweight or obesity without diabetes: network meta-analysis of randomised controlled trialsObjective To compare the efficacy and safety of glucagon-like peptide 1 (GLP-1) based drug treatments for weight loss in adults with overweight or obesity without diabetes.Design Network meta-analysis... 021
Reposted by Alexandre SerafimJAMA Cardiology @jamacardiology.com · 28/08/2026📝 Narrative Review: #RightVentricle metrics, such as strain, fractional area change, and ejection fraction, offer mechanistic insight in cardiovascular trials but remain underused due to acquisition variability and lack of standardization. ja.ma/4wDRKIrja.maRight Ventricular Metrics as End Points in Clinical TrialsThis narrative review discusses the current and emerging role of right ventricular–focused imaging and hemodynamic parameters as end points in clinical trials and a comprehensive framework for their development, validation, and broader implementation. 044
Reposted by Alexandre SerafimJohn Ross @johnrossmd.bsky.social · 05/09/2026Modern studies from the Amazon have shown that a 1% increase in deforestation is associated with a 6.3% increase in malaria casespnas.orgEcological change increases malaria risk in the Brazilian Amazon | PNASEcological change in the Brazilian Amazon is closely linked to human mobility and health. Mining, agriculture, logging, and other activities alter ... 12010
Reposted by Alexandre SerafimNEJM.org @nejm.org · 05/09/2026Among 16 patients with refractory neurologic autoimmune disorders, lentiviral CD19 CAR T-cell therapy was associated with manageable side effects, complete B-cell depletion, and preliminary clinical improvement across disease groups. Full trial results: nej.md/4zPPwbD 083
Reposted by Alexandre Serafimsccmcriticalcare.bsky.social @sccmcriticalcare.bsky.social · 05/09/2026Effective transitions of care are vital, particularly for children who have spent months in the NICU. Hear Philip D. Cohen, MD, MSc, discuss his PCCM article on non-emergent NICU to PICU transfers. 🎙️ sccm.org/pod575 #SCCM 021
Reposted by Alexandre SerafimHeidi Flori MD, FAAP @drheidiflori.bsky.social · 05/09/2026#PedsICU 👇 031
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 05/09/2026Biomarkers of perioperative neurocognitive disorders after cardiac surgery: from mechanistic insights to clinical translation CCR Journal Watch criticalcarereviews.com/latest-evid… 021
Reposted by Alexandre SerafimThe BMJ @bmj.com · 04/09/2026"People with relevant competing interests, particularly financial ones, should not be members of clinical or public policy guideline committees." @kamranabbasi.bsky.social on why the notion that transparency alone is enough hasn’t stood the test of timebmj.comThe £50m case for eliminating financial interests from clinical guidelines 263
Reposted by Alexandre SerafimISNkidneycare @theisn.org · 04/09/2026📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Anti-CD20 Therapies and Antinephrin Autoantibodies in IgA Nephropathy With Minimal Change Disease www.kireports.org/article/S2468-024… 054
Reposted by Alexandre SerafimCritical Care Reviews @criticalcarereviews.com · 02/09/2026Trauma-Induced Coagulopathy: From Endotheliopathy and Fibrinolysis Phenotypes to Viscoelastic-Guided Resuscitation CCR Journal Watch criticalcarereviews.com/latest-evid… 052
