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ATS Blue Journal

@atsblueeditor.bsky.social
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Posting content from the American Journal of Respiratory and Critical Care Medicine; follows do not indicate endorsement. #pulmCC #sleepmed #AJRCCM #RespEd #ATS #medsky www.atsjournals.org/journal/ajrccm

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ATS Blue Journal @atsblueeditor.bsky.social · 21h
🚨The October edition of the Blue Journal #AJRCCM is now available with special sections on Interstitial Lung Disease and Cystic Fibrosis. #ILD #CF academic.oup.com/ajrccm/issue... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 28/09/2026
Blood transcriptomic signatures predict poor outcomes in drug-susceptible pulmonary TB in Brazil doi.org/10.1093/ajrc... @atscommunity.bsky.social
doi.org
Blood transcriptomic signatures predict poor outcomes in drug-susceptible pulmonary tuberculosis in Brazil
AbstractRationale. Non-sputum biomarkers to monitor tuberculosis treatment and predict poor outcomes are lacking.Objectives. To evaluate host-blood transcr
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ATS Blue Journal @atsblueeditor.bsky.social · 28/09/2026
Identification of pulmonary arterial hypertension patients with venous or capillary involvement doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Identification of pulmonary arterial hypertension patients with venous or capillary involvement
AbstractRationale. While therapeutic advances have improved survival for patients with Group 1 pulmonary arterial hypertension (PAH), patients with Group 1
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ATS Blue Journal @atsblueeditor.bsky.social · 25/09/2026
Extracorporeal membrane oxygenation without invasive mechanical ventilation for acute respiratory distress syndrome: an international cohort study @atscommunity.bsky.social #ECMO doi.org/10.1093/ajrc...
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Extracorporeal membrane oxygenation without invasive mechanical ventilation for acute respiratory distress syndrome: an international cohort study
AbstractRationale. In acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) without invasive mechanical ventilation (IMV)
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ATS Blue Journal @atsblueeditor.bsky.social · 24/09/2026
Determinants of tidal recruitment/derecruitment assessed by electrical impedance tomography in spontaneously breathing ARDS patients @atscommunity.bsky.social doi.org/10.1093/ajrc...
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Determinants of tidal recruitment/derecruitment assessed by electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients
AbstractRationale. Tidal recruitment/derecruitment (R/D) is a well-known mechanism of lung injury in acute respiratory distress syndrome (ARDS) patients, b
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ATS Blue Journal @atsblueeditor.bsky.social · 23/09/2026
Extracorporeal life support in adult critically ill patients: mechanisms of benefit in respiratory and cardiac failure doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Extracorporeal life support in adult critically ill patients: mechanisms of benefit in respiratory and cardiac failure
Abstract. Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respirat
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ATS Blue Journal @atsblueeditor.bsky.social · 23/09/2026
Noninvasive respiratory support for adult patients with acute respiratory failure: An Official American Thoracic Society Clinical Practice Guideline doi.org/10.1093/ajrc...
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Noninvasive respiratory support for adult patients with acute respiratory failure: an official American Thoracic Society Clinical Practice Guideline
AbstractBackground. Acute hypoxemic and hypercapnic respiratory failure are among the most common reasons for ICU admission and need for invasive mechanica
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ATS Blue Journal @atsblueeditor.bsky.social · 22/09/2026
Effects of China’s clean heating policy on respiratory symptoms and airway inflammation in adults: a quasi-experimental study in rural Beijing @atscommunity.bsky.social doi.org/10.1093/ajrc...
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ATS Blue Journal @atsblueeditor.bsky.social · 22/09/2026
The frequent exacerbator phenotype in bronchiectasis revisited: data from EMBARC registry doi.org/10.1093/ajrc... @atscommunity.bsky.social
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The frequent exacerbator phenotype in bronchiectasis revisited: data from EMBARC registry
AbstractRationale. The frequent exacerbator phenotype was previously defined using a threshold of ≥3 exacerbations per year in bronchiectasis. However, the
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ATS Blue Journal @atsblueeditor.bsky.social · 21/09/2026
From mild-to-moderate to severe asthma: risk factors and patient profiles from the NORDSTAR cohort doi.org/10.1093/ajrc... @atscommunity.bsky.social
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From mild-to-moderate to severe asthma: risk factors and patient profiles from the NORDSTAR cohort
AbstractBackground. The progression from mild-to-moderate to severe asthma remains unclear. This study aimed to assess the risk of progression following th
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ATS Blue Journal @atsblueeditor.bsky.social · 21/09/2026
Airway microbiome diversity, intra-mucosal bacteria, and spatial immunity in asthmatics and controls doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Airway microbiome diversity, intramucosal bacteria, and spatial immunity in asthmatic adults and controls
AbstractRationale. Asthma is characterized by disruption of the thoracic airway mucosae and loss of microbial diversity. Spatial profiling of the mucosal t
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ATS Blue Journal @atsblueeditor.bsky.social · 20/09/2026
Airway mucus plugs in asthma and COPD: pathobiology, imaging, and implications for clinical trials doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Airway mucus plugs in asthma and chronic obstructive pulmonary disease: pathobiology, imaging, and implications for clinical trials
Abstract. Mucus plugs have been previously recognized as an important pathological feature in asthma and chronic obstructive pulmonary disease (COPD), but
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ATS Blue Journal @atsblueeditor.bsky.social · 19/09/2026
How the exposome shapes our respiratory health doi.org/10.1093/ajrc... @atscommunity.bsky.social
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How the exposome shapes our respiratory health
The exposome, reflecting the totality of an individual's exposures, is dynamic and exerts both short- and long-term effects on respiratory health and disea
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ATS Blue Journal @atsblueeditor.bsky.social · 18/09/2026
Diagnostic criteria for invasive pulmonary aspergillosis in COPD patients doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Diagnostic criteria for invasive pulmonary aspergillosis in chronic obstructive pulmonary disease patients
Abstract. More than 400 million people have chronic obstructive pulmonary disease (COPD), with exacerbations representing a major health burden. Although t
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ATS Blue Journal @atsblueeditor.bsky.social · 18/09/2026
Astegolimab for COPD with frequent exacerbations: pooled analysis of the ALIENTO and ARNASA trials doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Astegolimab for chronic obstructive pulmonary disease with frequent exacerbations: pooled analysis of the ALIENTO and ARNASA trials
AbstractRationale. The efficacy and safety of astegolimab, an anti-ST2 monoclonal antibody, was evaluated in participants with chronic obstructive pulmonar
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ATS Blue Journal @atsblueeditor.bsky.social · 17/09/2026
Defining disease stability in COPD: evidence from phase 3 clinical trials doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Defining disease stability in chronic obstructive pulmonary disease: evidence from phase 3 clinical trials
AbstractRationale. Disease stability in chronic obstructive pulmonary disease (COPD) is a low disease activity state proposed as a treatment target.Objecti
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ATS Blue Journal @atsblueeditor.bsky.social · 16/09/2026
Mepolizumab efficacy in COPD: insights from longitudinal patterns of blood eosinophil counts and their variability doi.org/10.1093/ajrc... @atscommunity.bsky.social
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Mepolizumab efficacy in chronic obstructive pulmonary disease: insights from longitudinal patterns of blood eosinophil counts and their variability across 3 clinical trials
AbstractRationale. Blood eosinophil count (BEC) is a biomarker indicating type 2 inflammation in patients with chronic obstructive pulmonary disease (COPD)
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ATS Blue Journal @atsblueeditor.bsky.social · 15/09/2026
Dupilumab in #COPD: a pooled analysis of emergency department visits, hospital admissions, and systemic corticosteroid use. @atscommunity.bsky.social doi.org/10.1093/ajrc...
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ATS Blue Journal @atsblueeditor.bsky.social · 14/09/2026
Tezepelumab in real-world U.S. patients with severe asthma across phenotypes and underrepresented populations: the phase 4 PASSAGE study doi.org/10.1093/ajrc... #asthma
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Tezepelumab in real-world US patients with severe asthma across phenotypes and underrepresented populations: the phase 4 PASSAGE study
AbstractRationale. Clinical trials of severe asthma therapies often exclude or underrepresent key patient populations.Objectives. To evaluate the effective
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ATS Blue Journal @atsblueeditor.bsky.social · 11/09/2026
The authors identified disease-causing variants in adenylate kinase 8 in patients with primary ciliary dyskinesia. doi.org/10.1093/ajrc... #PCD @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 09/09/2026
Interested in race and ethnicity in lung disease? Check out these reviews from the fellows at Queen’s University. doi.org/10.1093/ajrc...
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Race and ethnicity in lung disease
Race is a social construct based on current or perceived physical appearance and ancestry. Ethnicity is another social construct based on cultural behavior
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ATS Blue Journal @atsblueeditor.bsky.social · 08/09/2026
Blood RNA signatures measured during TB treatment predict recurrence and death, supporting biomarker-guided, personalized therapy. doi.org/10.1093/ajrc... @satviuct.bsky.social @simonidies.bsky.social @tomscriba.bsky.social
doi.org
Blood transcriptomic signatures predict poor outcomes in drug-susceptible pulmonary tuberculosis in Brazil
AbstractRationale. Non-sputum biomarkers to monitor tuberculosis treatment and predict poor outcomes are lacking.Objectives. To evaluate host-blood transcr
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ATS Blue Journal @atsblueeditor.bsky.social · 04/09/2026
Digital or peer interventions to improve CPAP adherence in OSA are likely to be feasible for adoption by healthcare systems. doi.org/10.1093/ajrc... #sleepapnea @atscommunity.bsky.social
doi.org
Implementing sleep apnea care to improve positive airway pressure adherence here and across the pond
Poor adherence to continuous positive airway pressure (CPAP) hampers benefits to patients with obstructive sleep apnea (OSA),1 and adherence rates have rem
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ATS Blue Journal @atsblueeditor.bsky.social · 03/09/2026
Low COPD maintenance inhaler prescribing was associated with longer drive time and greater neighborhood disadvantage, suggesting geographic barriers to care. @atscommunity.bsky.social doi.org/10.1093/ajrc...
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Geographic disparities in chronic obstructive pulmonary disease inhalers by rurality, drive time, and neighborhood disadvantage
To the Editor:
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ATS Blue Journal @atsblueeditor.bsky.social · 02/09/2026
CT-detected mucus plugs in COPD are linked to increased small airway resistance and ventilation heterogeneity on oscillometry. doi.org/10.1093/ajrc...
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Respiratory oscillometry in patients with chronic obstructive pulmonary disease with airway mucus plugs: insights from the ECLIPSE study
Airway-occluding mucus plugs are associated with lung function decline and all-cause mortality in chronic obstructive pulmonary disease (COPD).1,2 While sm
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ATS Blue Journal @atsblueeditor.bsky.social · 31/08/2026
The September edition of the Blue Journal is Live! Read the American Journal of Respiratory and Critical Medicine's Special Section on Airway Disease. #AJRCCM academic.oup.com/ajrccm/issue...
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ATS Blue Journal @atsblueeditor.bsky.social · 31/08/2026
The September edition of the Blue Journal is live! Read the American Journal of Respiratory and Critical Care Medicine's Special Section on Airway Disease. @atscommunity.bsky.social academic.oup.com/ajrccm/issue...
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ATS Blue Journal @atsblueeditor.bsky.social · 27/08/2026
🎧From The Archives: Episode of Out of the Blue: An AJRCCM Podcast Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline Listen Here: tinyurl.com/5n8f8m59 #Pneumonia @atscommunity.bsky.social
tinyurl.com
Out of the Blue: An AJRCCM Podcast | From The Archives: Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
From The Archives: Dr. John Fleetham chats with Dr. Barbara Jones about her ATS guideline, "Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical ...
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ATS Blue Journal @atsblueeditor.bsky.social · 26/08/2026
Olanzapine versus low-dose dexmedetomidine for delirium in patients with critical illness: a randomized clinical trial #criticalcare @atscommunity.bsky.social doi.org/10.1093/ajrc...
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Olanzapine versus low-dose dexmedetomidine for delirium in patients with critical illness: a randomized clinical trial
To the Editor:
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ATS Blue Journal @atsblueeditor.bsky.social · 25/08/2026
One Week Left! Apply to become the next Editor-in-Chief of AJRCCM Learn more here: tinyurl.com/42mmsmah @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 24/08/2026
Early real-world series suggests intravenous/subcutaneous prostacyclin de-escalation may be feasible in selected low-risk patients #PAH @atscommunity.bsky.social doi.org/10.1093/ajrc...
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Sotatercept and prostacyclin de-escalation in stable pulmonary arterial hypertension: a single-center case series
To the Editor:
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ATS Blue Journal @atsblueeditor.bsky.social · 21/08/2026
Spontaneous breathing trials predict inspiratory effort after extubation differently depending on whether oxygen, HFNC, or NIV are applied. doi.org/10.1093/ajrc...
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Reposted by ATS Blue Journal
American Thoracic Society (ATS) @atscommunity.bsky.social · 19/08/2026
Barbara Jones, MD, co-chaired the ATS’s 2025 clinical practice guideline on community-acquired pneumonia. The ATS is turning evidence into action by expanding guidelines and strengthening equity & the patient voice. Join the ATS or renew your membership today: site.thoracic.org/membership
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Reposted by ATS Blue Journal
Healthcare-Global @healthcare-global.bsky.social · 19/08/2026
www.miragenews.com/viral-enzyme...
miragenews.com
Viral Enzyme Disables Bacterial Defenses for Phages
Scientists have found how phages, viruses that infect bacteria, orchestrate an explosion of protein modifications inside host cells that helps them
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ATS Blue Journal @atsblueeditor.bsky.social · 18/08/2026
Post-tuberculosis lung disease in treated extra-pulmonary tuberculosis Not just post-TB: extra-pulmonary tuberculosis cases can have lasting lung impairment after treatment. Expanding post-TB screening is critical doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 17/08/2026
Subphenotypes of pneumonia defined by pulmonary histopathological features doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 14/08/2026
Cost-effectiveness of community tuberculosis screening in South Africa Community-based, symptom-agnostic TB screening with chest x-ray followed by confirmatory PCR testing would be cost-effective in South Africa doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 13/08/2026
Single-cell sequencing unveils a profibrotic macrophage and infiltrating monocyte niche in the bronchoalveolar lavage of patients with COPD BAL single-cell RNA sequencing reveals a global dysregulation of the immune landscape in COPD doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 12/08/2026
Deupirfenidone compared with pirfenidone and placebo in idiopathic pulmonary fibrosis (ELEVATE-IPF): a phase 2b randomized placebo-controlled trial Deupirfenidone slowed the rate of FVC decline compared with placebo in IPF doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 11/08/2026
Rocuronium dose and first-attempt intubation success in the critically ill: secondary analysis of two multicenter trials Among adults undergoing intubation with rocuronium, those receiving doses >1.2 mg/kg had higher first-pass success doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 07/08/2026
📰 AJRCCM in the News Black lung rates in Appalachia are high as the 1970s, with thousands of miners sick www.npr.org/2026/08/05/n... @hberkes.bsky.social @atscommunity.bsky.social
npr.org
Black lung rates in Appalachia are high as the 1970s, with thousands of miners sick
Rates are now the highest they've been in nearly 50 years among veteran coal miners. Mining experts blame toxic silica dust, now more common in mines.
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ATS Blue Journal @atsblueeditor.bsky.social · 06/08/2026
🎧 Just Released! A New Episode of Out of the Blue: An AJRCCM Podcast Pulmonary Rehabilitation Is Associated with Increased 1-Year Survival in Stable Chronic Obstructive Pulmonary Disease Listen here: tinyurl.com/3jfn2yzz @atscommunity.bsky.social
tinyurl.com
Out of the Blue: An AJRCCM Podcast | Pulmonary Rehabilitation Is Associated with Increased 1-Year Survival in Stable Chronic Obstructive Pulmonary Disease
Dr. Mohleen Kang interviews Dr. Stephanie Robinson and Dr. Marilyn Moy about their article, “Pulmonary Rehabilitation Is Associated with Increased 1-Year Survival in Stable Chronic Obstructive Pulm...
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ATS Blue Journal @atsblueeditor.bsky.social · 05/08/2026
Optimizing endpoints in early phase clinical trials of acute respiratory distress syndrome doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 03/08/2026
Discriminative performance and clinical utility of chronic obstructive pulmonary disease exacerbation categories for predicting future exacerbations doi.org/10.1093/ajrc... @suryapbhatt.bsky.social @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 31/07/2026
The August issue of #AJRCCM is now live! Take a look: academic.oup.com/ajrccm/issue... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 31/07/2026
📢 One Month Left! Apply to become the next Editor-in-Chief of AJRCCM Learn more here: tinyurl.com/42mmsmah @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 30/07/2026
BAL-derived extracellular vesicles to test ex vivo for endothelial injury in HIV patients on antiretroviral therapy doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 29/07/2026
10 mL/kg vs 20 mL/kg fluid bolus in pediatric septic shock: a randomized clinical trial In pediatric septic shock, 10 mL/kg vs 20 mL/kg fluid boluses showed similar early outcomes, with less fluid overload at 24 hours doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 28/07/2026
Relative contribution of driving pressure and respiratory rate to mortality in ARDS depends on age As age advances, driving pressure becomes relatively more important than respiratory rate to mortality in ARDS doi.org/10.1093/ajrc... @atscommunity.bsky.social
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ATS Blue Journal @atsblueeditor.bsky.social · 27/07/2026
Safety and antimicrobial efficacy of CSL787, a novel nebulized IgG therapy, in patients with bronchiectasis: results from a randomized phase 1 trial Inhaled immunoglobulin is safe in bronchiectasis and may reduce bacterial load and symptoms doi.org/10.1093/ajrc... @atscommunity.bsky.social
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