The authors used whole-exome sequencing and analysis of rare coding variation in individuals with obsessive–compulsive disorder and chronic tic disorders, including Tourette disorder, to identify 36 l...

Join the Department of Experimental and Applied Psychology (Vrije Universiteit Amsterdam) as Assistant Professor in cognitive neuroscience.

Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating p...

Nature Methods - Getting over ANOVA: estimation graphics for multi-group comparisons

LATeNT is a light-activatable form of tetanus neurotoxin that can be used for spatiotemporally precise inhibition of exocytosis in neurons and other cells. It can inhibit synaptic transmission in vivo...

The basolateral amygdala dopamine system has received little attention. Here, authors show that BLA dopamine plays a unique role in learning, by encoding the emotional salience of sensory cues to supp...

Catecholaminergic modulation by methylphenidate affects appetitive and aversive Pavlovian biases of approach and avoidance in humans depending on individual differences in working memory capacity.

Artificial intelligence is a democratizing force for those without graphic-design experience, as long as it is used conscientiously.

Serotonergic neurons in the dorsal raphe nucleus (DRN) project extensively throughout the forebrain, yet their influence on global network states remains controversial. Serotonin is implicated in regu...

A versatile platform of miniaturized Fourier-optics-based diffractive elements enables multifunctional pixels that fully control and sense the amplitude, phase and polarization of optical wavefronts for advanced photonic applications.

Opioid use disorder is a chronic, relapsing condition that continues to rise worldwide. Naloxone (Narcan®), an opioid antagonist, reverses overdose but triggers strong negative affect. The neuronal…

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

Researchers in the US have launched an awareness campaign on billboards, buses across Oregon and social media, alerting the public to the impact that the closure of the Oregon National Primate…

Representing EBRAINS, Europe's digital research infrastructure for brain research and brain-inspired technologies, Prof. Katrin Amunts, Joint CEO of…

If LLMs are increasingly used for data analysis, should we worry that they might encourage p-hacking? A recent preprint, also featured in Science Magazine, suggests that the answer may be yes, at lea...

Nature - Burnout is a systemic problem, but individuals can take steps to cope with it and pave a path forward.

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

Dopamine neurons projecting to distinct brain regions have unique biophysical properties, which is thought to reflect functional specialization. One defining feature is the duration of hyperpolarizati...

The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

The 2026 Gordon Research Conference on Frontal Cortex will be held in Holderness, New Hampshire. Apply today to reserve your spot.

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?

In this study, the authors find that synaptic strength predicts spine size and long-term stability via in vivo imaging together with optogenetic stimulation in awake mice. While individual synapses sh...