Head direction (HD) cells are required for spatial orientation. Protocols that combine functional identification with anatomical recovery of single HD neurons remain technically demanding. We present ...

A new preprint identifies two distinct populations of CA3 neurons, challenging the view that the hippocampal region is a single network.

Posted 12:00:00 AM. Job DescriptionDr. Abid Hussaini is seeking a highly motivated Postdoctoral Research Scientist to…See this and similar jobs on LinkedIn.

Susumu Tonegawa, a renowned MIT professor of biology and neuroscience and a Nobel laureate, has died at the age of 86. His discovery of how the immune system generates many different antibodies earned...

Hijazi and Jiang et al. identify distinct head direction (HD) cell subpopulations in the mouse anterodorsal thalamic nucleus, based on the combination of firing patterns, connectivity, and neurochemic...

Chowdhury et al. report the discovery of a 19–45-Hz thalamic oscillation that is present during human wakefulness and REM sleep, but not NREM sleep.

The autism spectrum has widened to the point of collapse, affecting how teachers should support autistic pupils in the classroom, researcher Uta Frith tells Helen Amass

Experts at Oxford are looking at how epilepsy can be prevented, diagnosed and treated, as well as promoting awareness of the condition to reduce stigma and improve quality of life for people with epil...

Peripheral cancer inhibits amyloid pathology and rescues cognition of Alzheimer’s disease through secretion of cystatin-c (Cyst-C), which binds amyloid oligomers and activates TREM2 in microglia and enables microglia to degrade pre-existing plaques.

Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal com...

I knew that a revolution in our understanding of soil could change the world. Then came a eureka moment – and the birth of the Earth Rover Program, says Guardian columnist George Monbiot

Deciphering body-brain communication pathways is key to a deeper understanding of brain physiology and pathology. Here, the authors define the astrocyte endfoot proteome and show dynamic vascular-to-a...

A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...

Jane Goodall Institute says ‘tireless advocate’ for natural world died in California during US speaking tour The world-renowned primatologist Jane Goodall has died at the age of 91, her institute has said. The Jane Goodall Institute announced that she had passed away of natural causes while in California as part of a US speaking tour. Continue reading...

What do we know about the causes of autism?

Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.

While the thalamus is known to relay and modulate sensory signals to the cortex, whether it also participates in active computation and intrinsic signal generation remains unresolved. The anterodorsal...

Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

Stimulation of the ventromedial hypothalamic region in animals has been reported to cause attack behavior labeled as sham-rage without offering information about the internal affective state of the an...

A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in

Recipients of honorary degrees at Oxford University today included a Nobel laureate and a multiple Olympic, World and European champion, and represented the fields of sport, entertainment,

From distant stars and galaxies to asteroids whizzing through the Solar System, this next-generation facility unveils its first imagery and brings the night sky to life like never before

Wilkins-Bernal-Medawar 2024 Prize Lecture delivered by Professor Matthew Cobb

Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...

Human high-order thalamic nuclei activity is known to closely correlate with conscious states. However, it is not clear how those thalamic nuclei and thalamocortical interactions directly contribute t...

Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.

Hippocampal ripples are highly synchronized neuronal population patterns reactivating past waking experiences in the offline brain. Whether the level, structure, and content of ripple-nested activity ...

Grid and place cells typically fire at progressively earlier phases within each cycle of the theta rhythm as rodents run across their firing fields, a phenomenon known as theta phase precession. Here...