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Ethan Greenblatt

@vancityflyguy.bsky.social
887 followers 722 following 23 posts

Asst. Prof. at UBC 🇨🇦🇺🇸. Interested in oocytes-the coolest cells in all biology. We study RNA, aging, (in)fertility, and neurodevelopmental disorders including fragile X syndrome.

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Reposted by Ethan Greenblatt
callista yee @csybio.bsky.social · 06/08/2026
hiiii everyone! my department @zoology.ubc.ca is hiring an assistant professor in cell and developmental biology! deadline is october 1! academicjobsonline.org/ajo/jobs/32408 // please share!!!!!
academicjobsonline.org
University of British Columbia, Department of Zoology
Job #AJO32408, Assistant Professor in Cell and Developmental Biology, Department of Zoology, University of British Columbia, Vancouver, British Columbia, CA
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 26/07/2026
I love biology--after decades of study, we're still learning new and surprising things about one of the best studied reproductive systems, that of the female fruit fly pubmed.ncbi.nlm.nih.gov/42489076/

Development

. 2026 Jul 23:dev.205668.
doi: 10.1242/dev.205668. Online ahead of print.
The Drosophila ovary produces two waves of adult follicles and a novel pupal wave that turns over
Wayne Yunpeng Fu  1   2   3 , Allan C Spradling  1   2   3
Affiliations

    PMID: 42489076 DOI: 10.1242/dev.205668 

Abstract

Ovarian follicles in most species are assumed to develop using a single pathway. However, in Drosophila pupae, lineage tracing 2,937 single-cell clones identified three follicle "waves" that follow distinct programs arrayed anterior to posterior in the germarium and developing ovarioles. 40 primordial germ cells (PGCs) become anterior germline stem cells (GSCs) that produce "wave 2" follicles throughout adulthood. 100 PGCs posterior to wave 2 develop into "wave 1.5" follicles that form the earliest laid eggs. Different follicle stem cells (FSCs) sequentially occupy the same two niches timed to provide both waves with specific follicle cells, consistent with programmed differences between waves 2 and 1.5. "Wave 1" PGCs located even further posterior proliferate, form cysts, interact with swarm cells, degenerate, break from the ovary 22-26 hours after puparium formation, and release lipid-enriched vacuoles. Some testis germ cells behave similarly. We speculate that wave 1 germ cells contribute directly or indirectly to the pharate adult ecdysone pulse that mediates adult development and sex-specific neural remodeling. Why Drosophila follicle waves generally resemble those clarified recently in mouse preadult ovaries merits additional study.
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Ethan Greenblatt @vancityflyguy.bsky.social · 24/07/2026
I'm incredibly proud of my lab's work defining the mechanism by which fragile X messenger ribonucleoprotein (FMRP) supports translation of long neurodevelopmental mRNAs - a discovery we first made in fruit fly eggs later shown to be conserved in the mammalian brain  www.biorxiv.org/content/10.6...
biorxiv.org
FMRP prevents Me31B/DDX6-associated repression of long neurodevelopmental mRNAs
Long, dosage-sensitive mRNAs encoding neurodevelopmental regulators are selectively dependent on fragile X messenger ribonucleoprotein (FMRP) for efficient translation across animal systems, but the m...
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Ian L Morgan @ianlmorgan.bsky.social · 28/03/2026
Powerful speeches this morning from @michaeldgreen.phd and many others at today's #nokings edition of #nihvigils. Shoutout to @27unihted.bsky.social, @nihvigils.bsky.social, and all the great organizers who made the event possible.
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Kevin Mitchell @wiringthebrain.bsky.social · 16/07/2025
This isn't a coincidence, IMO. The fly community is generally super rigorous - because there are so many tools and techniques available, people expect you to really nail things in order to get published (and keep getting funded)
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Science in Boston @scienceinboston.com · 10/07/2025
Certain alleles, called meiotic drivers, cheat the rules of inheritance to increase the chance of transmission. The Yamashita lab at the @whiteheadinstitute.bsky.social investigated genetic information transmission and found a meiotic driver that operates differently: bit.ly/4nzcFcp
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Ethan Greenblatt @vancityflyguy.bsky.social · 15/06/2025
Making my voice heard at the #nokings protest in Vancouver!
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Sheila Teves @sheilateves.bsky.social · 22/05/2025
So excited to see this work out in @narjournal.bsky.social academic.oup.com/nar/article/... Congratulations to Hazel Cui on outstanding work! Keep an eye out for part 2 of this project 😎
academic.oup.com
Validate User
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Amanda Burnham @amandaburnham.bsky.social · 19/04/2025
The Sondheim Finalists’ Exhibition at @thewaltersartmuseum is open as of TODAY! I am so thrilled to share this new work and hope you will see it! “…and Find Out.” (detail), watercolor, ink, and acrylic on paper, 22 x 30 x 1”, 2025
Small detail of a dimensional collage with disembodied hands and water droplets in blue, yellow, green, and black
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Barack Obama @barackobama.bsky.social · 15/04/2025
Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.
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Florencia Pratto @florpratto.bsky.social · 09/04/2025
Check this out if you ever wondered what intercellular bridges might be doing during meiosis! Happy to have played a small role! Congrats!!! @thejainlab.bsky.social
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Ethan Greenblatt @vancityflyguy.bsky.social · 14/03/2025
Come be my colleague at UBC! A great place to work w/amazing students, a beautiful campus, and…maybe one or two other perks 🇨🇦
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Ardem Patapoutian @ardemp.bskyverified.social · 07/03/2025
Quick tip: If your paper was published today, consider sharing it on social media tomorrow instead. Today, everyone's focus is on Standing Up for Science and making some good trouble!
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Harmit Singh Malik @harmitmalik.bsky.social · 01/03/2025
Heartbreaking chats this week with students thinking of giving up on their dreams of getting a PhD. They worry about getting in PhD programs and careers post PhD. My suggestions: don’t be hasty, think broadly incl EU & Canada, & careers beyond traditional academia. What’re you telling your students?
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Scott Delaney @scott-delaney.bsky.social · 20/02/2025
The MassBio brief says they represent 1700 biotech / pharma companies in MA. They cite a recent study showing that "funding from NIH contributed to 354 of 356 drugs approved from 2010-2019." (!!!) And they argue the policy will have irreparable harm on drug development.
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Kara Swisher @karaswisher.bsky.social · 19/02/2025
Math is hard
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André K. Isaacs @drdre4000.bsky.social · 05/02/2025
Just got word that our Howard Hughes Medical Institute (HHMI) Inclusive Excellence 3 (IE3) Grant was being canceled. All 100+ institutions. So even private funding is susceptible to this administration’s unraveling of DEI initiatives
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Richard Zussman @richardzussman.bsky.social · 02/02/2025
Red state alcohol is currently being removed at B.C. Liquor store in Victoria. #bcpoli
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Abby Dernburg @adernburg.bsky.social · 22/01/2025
MAYosis is coming... register and submit abstracts here. meiosis.cornell.edu/mayosis2025/...
meiosis.cornell.edu
MAYosis 2025
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Amitav Bhattacharjee 🦋 @amitav63.bsky.social · 20/01/2025
NASA's James Webb Telescope discovers alcohol cloud in deep space! To drink all of that, every person on earth would have to drink 300,000 pints each day for one billion years. www.wionews.com/web-stories/... #NASA #JamesWebb #alcohol #space #spaceeploration
wionews.com
NASA's James Webb Telescope discovers alcohol cloud in deep space
Science: NASA's James Webb Telescope reveals an alcohol cloud in the depths of space, marking a significant step in exploring cosmic phenomena and interstellar chemistry.
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HunterLab.bsky.social @hunterlab.bsky.social · 15/01/2025
📢The 2025 MAYosis webinar series will be held on consecutive Wednesdays, May 7-28, at 4 pm CET (7 am PST; 12 am JST) meiosis.cornell.edu/mayoss2025/ Apply to give a talk (deadline is March 8, trainees and junior faculty only): tinyurl.com/47k3cjpn Registration is free: tinyurl.com/39rs53yv
meiosis.cornell.edu
MAYosis 2025
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Sue Biggins @suebiggins.bsky.social · 14/01/2025
Our latest work using TIRFM to uncover mechanisms that stabilize the centromeric nucleosome: www.embopress.org/doi/full/10....
embopress.org
Stable centromere association of the yeast histone variant Cse4 requires its essential N-terminal domain | The EMBO Journal
imageimageCentromeres contain a histone H3 variant that is essential for kinetochore assembly. This work reports that the extended N-terminus of the budding yeast centromeric histone, Cse4, stabilizes...
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Harmit Singh Malik @harmitmalik.bsky.social · 23/12/2024
Congrats to all the newly elected members of the GSA Board of Directors, including TAGC24 veteran @barrlab.bsky.social genestogenomes.org/new-members-...
genestogenomes.org
New members of the GSA Board of Directors: 2025–2027
We are pleased to announce the election of six new leaders to the GSA Board of Directors: 2025 Vice President/2026 President Cassandra Extavour Timken Professor of Organismic & Evolutionary Biology an...
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W. Brent Derry @wbderry.bsky.social · 07/12/2024
If you want to learn about how a tiny worm led to major insights in developmental biology and human disease check out the Nobel lectures from Victor Ambros and Gary Ruvkun. www.youtube.com/watch?v=VQ9N...
youtube.com
2024 Nobel Prize lectures in physiology or medicine | Victor Ambros and Gary Ruvkun
YouTube video by Nobel Prize
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UCL Neuroscience @uclnpp.bsky.social · 27/11/2024
Lets start with something exciting! Applications are now open to join our fantastic department as a group leader fellow! Come start your independent group at (in our opinion) the best neuroscience department! reach out here or @macaskillaf.bsky.social for more info! www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Abby Dernburg @adernburg.bsky.social · 21/11/2024
Ru-upping this thread from last year since the paper is now out! @chenshuliu.bsky.social identified a Piezo-dependent mechanism that enables C. elegans to sniff out “bad eggs” and target them for destruction. www.science.org/doi/10.1126/...
science.org
Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope
Sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is crucial for a...
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Ardem Patapoutian @ardemp.bskyverified.social · 22/11/2024
Hey folks! I got a tattoo of my beloved PIEZO ion channel on my arm! Now I can show how they activate (flatten) under pressure by flexing—Will add a bit of performance art to my science talks 🧪🧠.
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Esther Verheyen 🇨🇦 @estherverheyen.bsky.social · 20/11/2024
Hello Bsky folks - here is a paper that we published earlier this year - great collaboration with the Bellen lab, Hyung-lok Chung, @okanca.bsky.social and others. Have a look if you're interested in Cdk8/19, mitochondria, Parkinsonism and Drosophila!
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Mark A. Hanson @hansonmark.bsky.social · 18/11/2024
Happy Fly Day! November 18th is #Drosophila day. It commemorates the isolation of a white-eyed mutation, which is now used across the world. That mutation is white[1118], with the numbers standing for Nov 18th, the day it was isolated by Bob Levis. 🪰
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Lerit Lab @lablerit.bsky.social · 12/11/2024
Now that half of SciTwitter is here… Come be my colleague! The Dept of Cell Biology @EmoryUniversity is recruiting a developmental cell biologist. 🔬Do you study mechanisms of development using cell biological (and other) approaches? Join us!🔬 TY for RT! jobs.sciencecareers.org/job/664684/t...
jobs.sciencecareers.org
Tenure-track Faculty position in Cell and Developmental Biology - Atlanta, Georgia job with Emory University | 664684
This search is open to investigators conducting mechanistic studies of developmental cell biology using genetically tractable model organisms.
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Ethan Greenblatt @vancityflyguy.bsky.social · 17/11/2024
I love iBiology videos and have learned so much by watching them. Also highly recommend the Conversations in Genetics series ft. amazing interviews of folks like Benzer and Jacob: www.youtube.com/@conversatio...
youtube.com
Conversations in Genetics
“Conversations in Genetics” is an oral history of our intellectual heritage in genetics. It is comprised of a series of video interviews with prominent scientists who made major contributions to the c...
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Amanda Burnham @amandaburnham.bsky.social · 15/11/2024
Belated intro post given the recent influx: Hi!👋 I’m Amanda. I’m a long time artist (mostly drawing and installation) more recently very into comics (most of which haven’t seen the light of day - yet 😊) Here’s a recent short comic!
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Harmit Singh Malik @harmitmalik.bsky.social · 13/11/2024
Very sad to hear of the passing of Joanne Chory, who was an iconic scientist and person. Truly, one can say she spent her whole career trying to make a better planet and a better environment in science for all. Interview: www.sebiology.org/resource/in-... TED talk: www.ted.com/speakers/joa...
sebiology.org
In conversation with… Joanne Chory
“I’m excited that people are finally letting us remind them that plants exist and that they are here for a reason,” says Professor Joanne Chory, plant geneticist at the Plant Biology Group of the Salk...
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Ethan Greenblatt @vancityflyguy.bsky.social · 12/11/2024
Hi Bluesky 🦋👋. Really don’t have time for fascist enabling social media platforms at the moment
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Swathi Arur @swathiarur.bsky.social · 11/11/2024
go.bsky.app/JJiPeti Here’s a list. Let’s add all those that my app missed!
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