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Tabea Schoeler

@tabeasch.bsky.social
238 followers 169 following 26 posts

Researcher at University of Lausanne | interested in genetic epidemiology, mental health & behaviour

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Reposted by Tabea Schoeler
Ted Schwaba @tedmond.bsky.social · 02/09/2026
Our big Big Five GWAS, out today! Personality Genomics is extremely hot in 2026.
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Nature Human Behaviour @nathumbehav.nature.com · 17/08/2026
Parental haplotype reconstruction in up to 440,209 UK and Estonian individuals reveals recent assortative mating dynamics
dlvr.it
Parental haplotype reconstruction in up to 440,209 UK and Estonian individuals reveals recent assortative mating dynamics
Nature Human Behaviour, Published online: 17 August 2026; doi:10.1038/s41562-026-02556-8Reconstructing parental haplotypes for up to 440,209 UK and Estonian Biobank participants, the authors estimate genetic assortative mating across 69 traits and find that assortment for height and education has intensified in recent generations.
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Tabea Schoeler @tabeasch.bsky.social · 06/07/2026
📢 Join us for the next #ReproT with Prof. Kevin Esterling! He'll be discussing: 💡 𝗧𝗵𝗲 𝗻𝗲𝗰𝗲𝘀𝘀𝗶𝘁𝘆 𝗼𝗳 𝗰𝗼𝗻𝘀𝘁𝗿𝘂𝗰𝘁 𝗮𝗻𝗱 𝗲𝘅𝘁𝗲𝗿𝗻𝗮𝗹 𝘃𝗮𝗹𝗶𝗱𝗶𝘁𝘆 𝗳𝗼𝗿 𝗰𝗮𝘂𝘀𝗮𝗹 𝗶𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 📅 When: Wednesday 8th July, 3pm (BST) Sign up here: rb.gy/8ptyey @jessiebaldwin.bsky.social @reproducibilitea.org @ukrepro.bsky.social
rb.gy
The necessity of construct and external validity for causal inferernce
What does it take to make a credible causal claim?
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Reposted by Tabea Schoeler
bioRxiv Genetics @biorxiv-genetic.bsky.social · 11/06/2026
Evaluating anonymized genome re-identification using polygenic predictions and its implications for data privacy www.biorxiv.org/content/10.64898/20…
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Jessie Baldwin @jessiebaldwin.bsky.social · 15/04/2026
How reproducible is cohort research? 🔍📊 Join us to find out from Laurie Hannigan at UCL/UNIL ReproducibiliTea 🫖 📅 23rd April, 1pm BST / 2pm CEST www.eventbrite.co.uk/e/transparen... @tabeasch.bsky.social @reproducibilitea.org @ukrepro.bsky.social @swissrn.bsky.social @uclopenscience.bsky.social
eventbrite.co.uk
Transparency in epidemiological cohort studies, with Dr Laurie Hannigan
Laurie Hannigan will present a case study on improving transparency and reproducibility in epidemiological cohort research
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Reposted by Tabea Schoeler
Abdel Abdellaoui @dr-appie.bsky.social · 24/03/2026
Me & @aysuo.bsky.social are hiring a postdoc to study gene–environment interplay in health & social inequalities 🧬 You'll analyze genomic data as part of a collaboration with Uppsala & Oslo at @amsterdamumc.bsky.social (NL) werkenbij.amsterdamumc.org/en/vacatures... Please RT for karma points ♥️
werkenbij.amsterdamumc.org
Vacatures - Postdoctoral researcher specialising in gene–environment interplay - Amsterdam UMC
Ready to unravel the complex interplay between genes and environment shaping health and society? Join our interdisciplinary team analyzing large-scale genomic data across Europe. Are you eager to contribute to groundbreaking research on health and social inequalities?
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Na Cai @caina89.bsky.social · 22/02/2026
Our new preprint “Learning lifetime disease liability reveals and removes genetic confounding in electronic health records” is now online! Link to paper: This work is led by my postdoc Yazheng Di and it’s our first project at @bsse.ethz.ch :) medrxiv.org/cgi/content/... Thread 1/n
medrxiv.org
Learning lifetime disease liability reveals and removes genetic confounding in electronic health records
Electronic health records (EHRs) have become the cornerstone of population-scale genetic studies1, but factors including patterns of healthcare use shape which and how diagnoses are recorded, leading ...
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lkarwatowska.bsky.social @lkarwatowska.bsky.social · 08/01/2026
🚨 Our new meta-analysis on the causal influence of parenting on disruptive behaviour (DBDs) is now published in Psychological Bulletin. Across 45 quasi-experimental (QE) studies (N ≈ 38,600), we find a small but causal effect of negative parenting on DBDs.
Title page of a Psychological Bulletin article titled “Positive and Negative Parenting Practices and Offspring Disruptive Behavior: A Meta-Analytic Review of Quasi-Experimental Evidence,” listing authors Lucy Karwatowska, Francesca Solmi, Jessie R. Baldwin, Sara R. Jaffee, Essi Viding, Jean-Baptiste Pingault, and Bianca Lucia De Stavola, with institutional affiliations and abstract text below.
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Jessie Baldwin @jessiebaldwin.bsky.social · 07/01/2026
Can AI be used to evaluate open science practices? 🤖🔎 Join us to find out from Dr Daryl Lee at the next ReproducibiliTea! 🫖 📅 Jan 13th, 3pm GMT www.eventbrite.co.uk/e/evaluating... @tabeasch.bsky.social @uclopenscience.bsky.social @uclpals.bsky.social @reproducibilitea.org @ukrepro.bsky.social
eventbrite.co.uk
Evaluating open science practices with AI, with Dr Daryl Lee
Join Dr. Yu Heng Daryl Lee to learn about the efficacy of AI in evaluating open science practices.
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Jessie Baldwin @jessiebaldwin.bsky.social · 11/11/2025
How many preregistered studies end up in the file drawer? 🗂️ Join us to find out from Eline Ensinck at the next ReproducibiliTea! 📅Nov 25, 3pm GMT www.eventbrite.co.uk/e/are-prereg... @tabeasch.bsky.social @reproducibilitea.org @uclopenscience.bsky.social @ukrepro.bsky.social @lakens.bsky.social
eventbrite.co.uk
Are Preregistered Studies Publicly Shared? With Eline Ensinck
Eline Ensinck will present research on the number of preregistered studies which are never published and the reasons behind this
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Reposted by Tabea Schoeler
Adriaan @adriaan-vd-graaf.bsky.social · 14/10/2025
Hi #ASHG2025, the Lausanne team made it to Boston ! Excited to present our latest discoveries — come say hi and learn more about our research! @samuelmoix.bsky.social @rjhfmstr.bsky.social
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Jessie Baldwin @jessiebaldwin.bsky.social · 10/10/2025
I'm hiring! ✨ Looking for a Research Fellow to study environmental factors that mitigate intergenerational transmission of mental health. 3-year post at UCL @uclbrainscience.bsky.social with great opportunities for training, collaboration & exciting science! 🔗 Apply: www.jobs.ac.uk/job/DOZ633/r...
jobs.ac.uk
Research Fellow in Mental Health at UCL
Apply for the Research Fellow in Mental Health role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
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Jessie Baldwin @jessiebaldwin.bsky.social · 13/10/2025
When is it appropriate to deviate from a pre-registration, and how should this be done? 🧐 Join us to find out from Daniël Lakens @lakens.bsky.social at the next ReproducibiliTea! October 28, 1pm GMT. Sign up: www.eventbrite.co.uk/e/when-and-h... @tabeasch.bsky.social @reproducibilitea.org
eventbrite.co.uk
When and How to Deviate From a Preregistration, with Prof Daniël Lakens
Prof Daniël Lakens will share guidance on appropriate circumstances and methods for deviating from a pre-registration
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Robin Hofmeister @rjhfmstr.bsky.social · 26/09/2025
🚨 New preprint out! We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation. This reveals intensified assortment in recent generations. www.biorxiv.org/content/10.1...
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Andrew Grotzinger @andrewgrotzinger.bsky.social · 06/08/2025
Amazing work from my colleague and postdoc Dr. Isabelle Foote on the genetic architecture of frailty. Encourage you to check it out!!!!
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Robin Hofmeister @rjhfmstr.bsky.social · 06/08/2025
🚨 Our parent-of-origin study is out in Nature! 🧬 Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss. 🔗 www.nature.com/articles/s41... Highlights below!
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Tabea Schoeler @tabeasch.bsky.social · 08/07/2025
🚨New preprint is out! How do genetic effects on complex traits change with age? In this work, we compare different approaches to obtain age-varying genetic effects, and show how design and modeling choices can impact the conclusions we draw. shorturl.at/17snd A thread 🧵👇
shorturl.at
Design and model choices shape inference of age-varying genetic effects on complex traits
Understanding how genetic influences on complex traits change with age is a fundamental question in genetic epidemiology. Both cross-sectional (between-subject) and longitudinal (within-subject) appro...
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Adriaan @adriaan-vd-graaf.bsky.social · 04/07/2025
Our paper, MR-link-2 has just been published! Offering pleiotropy robust Mendelian randomization from a single region! www.nature.com/articles/s41...
A network of metabolites and their potential causal relationships. Green edges are Detected by the statistical causal inference method MR-link-2
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Swiss Network for Dementia Research @handle.invalid · 24/06/2025
READING RECOMMENDATION 📖 Genes, environment, and aging: What determines cognitive and physical decline? Using newly available longitudinal aging data from the UK Biobank, @tabeasch.bsky.social and colleagues uncovered genetic and environmental factors influencing cognitive and physical decline.
nature.com
Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline - Nature Communications
The genetics of human aging remains poorly understood due to limited longitudinal data. Here, the authors show distinct genetic architectures for baseline function and decline in cognitive and physica...
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Eivind Ystrom @eivindy.bsky.social · 13/06/2025
🧵 THREAD: Preprint from @chrisrayner.bsky.social reveals how to fix selection bias in the Norwegian #MoBa study using population-wide registry data! For the first time, we can quantify and adjust for selection bias in this major epidemiological resource. Spread the good news! osf.io/preprints/os...
osf.io
OSF
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Margherita Malanchini @marghmalanchini.bsky.social · 10/06/2025
🧠🧬🧑‍🤝‍🧑 New CoDE Lab study: Disorder-specific genetic effects drive the associations between psychopathology and cognitive functioning. Link to preprint: www.medrxiv.org/content/10.1... Led by the brilliant Wangjingyi Liao 🌟 A short thread summarising the study👇
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Ted Schwaba @tedmond.bsky.social · 20/05/2025
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
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Aysu Okbay @aysuo.bsky.social · 20/05/2025
PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
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Tabea Schoeler @tabeasch.bsky.social · 19/05/2025
Happy to share our new study on genetic & environmental contributors to age-related decline in ~100K UK Biobank participants! Here, we used simulation work + longitudinal GWAS and downstream analyses to explore risks involved in cognitive/physical decline (1/)🧵🧵 shorturl.at/99gqL
shorturl.at
Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline - Nature Communications
Large-scale genomic studies focusing on the genetic contribution to human aging have mostly relied on cross-sectional data. With the release of longitudinally curated aging phenotypes by the UK Bioban...
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Saloni @scientificdiscovery.dev · 08/05/2025
On June 6th, I'll be giving a keynote talk at the Swiss Federal Office for Public Health! It's part of a one day workshop on the benefits and challenges in communicating long-term data in public health 📈📊📉 Join if you can! ☺️
Poster for a workshop titled “Benefits & challenges of communicating long-term data in public health” held on June 6th, 2025, from 10:00 to 16:00 at the Federal Office of Public Health, Schwarzenburgstrasse 157, 3097 Liebefeld, Switzerland. Organized by SSPH+, the Swiss Federal Office of Public Health, University of Zurich, and University of Fribourg. 
Schedule for the workshop “Benefits & challenges of communicating long-term data in public health” on June 6th, 2025. Program includes:

10:00–10:20: Welcome by Prof. Kaspar Staub and Prof. Arnaud Chiolero

10:20–11:00: Keynote speech by Dr. Saloni Dattani from Our World in Data

11:00–11:30: Coffee break

11:30–12:45: Snapshot perspectives on values and challenges of using long-term data, with talks on catastrophism, trust in data, journalism, public health authorities, and dashboards

12:45–13:45: Lunch and networking

13:45–14:00: Societal perspective by Prof. Dina Pomeranz

14:00–15:00: Group work on strategies for dissemination, trust, and data challenges

15:00–15:20: Coffee break

15:20–16:00: Wrap-up session on countering erosion of trust in science and health communication
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Angelica Ronald @angelicaronald.bsky.social · 07/05/2025
Our gene discovery project on age at onset of walking is out today! Find the paper here www.nature.com/articles/s41... Huge thanks to the cohorts, collaborators & coauthors, in particular first author Dr Anna Gui 1/n
nature.com
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and gene...
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Zoltán Kutalik @zkutalik.bsky.social · 29/04/2025
Very excited to give a virtual talk as part of the @eshg.bsky.social webinar series tomorrow at 4pm (CEST). If you want to listen in, register here: wma.eventsair.com/eshg-webinar... I will talk about all the exciting things we can learn from GWAS summary statistics...
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Sonja Lehtinen @sonjalehtinen.bsky.social · 28/04/2025
Come work with us! We're looking of postdoc(s) with experience in bacterial genomics and interest in mathematical modelling to work on bacterial ecology and evolution in the context of public health. tinyurl.com/n34vzszu
tinyurl.com
Opportunités de carrière : Postdoctoral researcher in bacterial genomics (22209)
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European Society of Human Genetics @eshg.bsky.social · 03/04/2025
The recording of the second episode of our #ESHG Webinar Series is now on YouTube. 🔜 Episode 3 – April 30, 16:00 CEST 📌 "Making sense of genetic associations" 🎙️ Zoltan Kutalik Join for free on Zoom! Register here: buff.ly/l6d0fai
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Marie Sadler @smarie-smarie.bsky.social · 01/04/2025
We study the genetics of drug efficacy using longitudinal biomarker and medication prescription data from #EHRs. 🧬💊 Have a look at the 🧵 on i) modelling drug response and biomarker progression, ii) using #PRS to predict efficacy and iii) the challenges with #EHRs. www.nature.com/articles/s41...
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Andrea Allegrini @andrealle.bsky.social · 20/03/2025
Our work on intergenerational transmission of psychiatric risk is now out!! www.nature.com/articles/s41... @naturecomms.bsky.social with thanks to my super coauthors @leofrach.bsky.social @jessiebaldwin.bsky.social and several others who made this possible
nature.com
Intergenerational transmission of polygenic predisposition for neuropsychiatric traits on emotional and behavioural difficulties in childhood - Nature Communications
Parental neuropsychiatric traits relate to children’s emotions and behaviours beyond genetic transmission alone. Here the author's findings suggest potential environmental risk factors that can act on...
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Zoltán Kutalik @zkutalik.bsky.social · 19/03/2025
Join us in Lausanne for a newly launched Computational Biology Symposium with a stellar lineup of speakers! Registration and abstract submission open: share your original research work in a friendly atmosphere!
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Einstein Foundation Berlin @einsteinberlin.bsky.social · 14/03/2025
🏆 Research integrity consultant and image forensics expert @elisabethbik.bsky.social has uncovered fraudulent data in over 7,600 scientific papers and exposed the practices of ‘paper mills’ that produce counterfeit scientific articles. She is honoured with the €200K Individual Award. Congrats!
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Angelica Ronald @angelicaronald.bsky.social · 11/03/2025
The London Genetics Network has arrived on Bluesky! Follow us here if you'd like @ldngenenet.bsky.social
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Peter Tennant @pwgtennant.bsky.social · 24/02/2025
"Selection bias: where are we now?" Incredibly excited to announce the next Causal Inference Interest Group seminar with @haidonglu.bsky.social will take place on 10th March 2025 at 3pm GMT (11am EDT). Don't miss this one! Register at: turing-uk.zoom.us/meeting/regi... #EpiSky #CausalSky #CIIG
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Leonard Frach @leofrach.bsky.social · 05/02/2025
New paper by the MoBa PsychGen team on 'direct and indirect genetic effects on early neurodevelopmental traits', led by Laura Hegemann. Now published in JCPP @acamh.bsky.social with @rosacheesman.bsky.social, @ludvigdb.bsky.social, @bstpourcain.bsky.social et al. doi.org/10.1111/jcpp...
doi.org
<em>Journal of Child Psychology and Psychiatry</em> | ACAMH Pediatric Journal | Wiley Online Library
Background Neurodevelopmental conditions are highly heritable. Recent studies have shown that genomic heritability estimates can be confounded by genetic effects mediated via the environment (indire.....
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Robin Hofmeister @rjhfmstr.bsky.social · 21/01/2025
🚨 Preprint update! We expanded our study on parent-of-origin effects with new findings from the MoBa cohort, now leveraging up to 265,000 individuals! Discover fresh insights into the genetic architecture of early growth! Updated preprint: www.medrxiv.org/content/10.1...
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Tabea Schoeler @tabeasch.bsky.social · 14/01/2025
Last chance to sign up for Dr Kara Kedrick’s talk tomorrow: 👇 𝐂𝐨𝐧𝐜𝐞𝐩𝐭𝐮𝐚𝐥 𝐬𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐠𝐫𝐨𝐰𝐭𝐡 𝐨𝐟 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐤𝐧𝐨𝐰𝐥𝐞𝐝𝐠𝐞 When: 15. January, 4pm (CET) Sign up here: shorturl.at/X4Ksn @jessiebaldwin.bsky.social @reproducibilitea.org
shorturl.at
Conceptual structure and the growth of scientific knowledge
In this session, Dr Kara Kedrick will present her work examining how scientific knowledge grows.
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Rebecca Sear @rebeccasear.bsky.social · 19/12/2024
“Our findings highlight that both self-report accuracy and selective participation are competing biases and sources of poor reproducibility for biobank-scale research” www.nature.com/articles/s41...
nature.com
The impact of self-report inaccuracy in the UK Biobank and its interplay with selective participation - Nature Human Behaviour
Biobank data are extensively used. Schoeler and colleagues show that self-report inaccuracy and selective participation are sources of poor reproducibility for biobank-scale research.
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Tabea Schoeler @tabeasch.bsky.social · 19/12/2024
Just out in @naturehumbehav.bsky.social ! We focused on the causes & impact of self-report error in the UK Biobank. We found that reporting error does not occur at random, is not independent of other participation behaviours, and can complicate the interpretation of GWA findings shorturl.at/N4Qc6
shorturl.at
The impact of self-report inaccuracy in the UK Biobank and its interplay with selective participation - Nature Human Behaviour
Biobank data are extensively used. Schoeler and colleagues show that self-report inaccuracy and selective participation are sources of poor reproducibility for biobank-scale research.
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Robin Hofmeister @rjhfmstr.bsky.social · 06/12/2024
🚨 Our preprint on parent-of-origin effects (POEs) is out! With our novel method, we inferred the parental origin of alleles for >220,000 individuals, uncovering novel insights into genetics, evolution, and health. 👉 Read here: www.medrxiv.org/content/10.1... 👇 Highlights below!
medrxiv.org
Parent-of-Origin inference and its role in the genetic architecture of complex traits: evidence from ~220,000 individuals
Parent-of-origin effects (POEs) occur when the impact of a genetic variant depends on its parental origin. Traditionally linked to genomic imprinting, these effects are believed to have evolved from p...
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Peter Tennant @pwgtennant.bsky.social · 02/12/2024
PLEASE SHARE: Registration is now open for the next Introduction to Causal Inference Course for Health & Social Scientists (7-11 July 2025, Leeds, UK). See more info & register here: www.causal.training Note, we are not planning any other courses until 2027. #CausalIntroCourse #EpiSky #CausalSky
Flyer for the Introduction to Causal Inference Course for Health & Social Scientists, taking place on 7th-11th July 2025
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