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Beate St Pourcain

@bstpourcain.bsky.social
864 followers 164 following 33 posts

genetic epidemiologist, mum of twins, rose gardener, occasional expression of an opinion

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Beate St Pourcain @bstpourcain.bsky.social · 21/09/2026
Genetic correlations of social behaviour with ADHD, MDD, autism and schizophrenia showed different developmental patterns, inferred from the social-behaviour GWAS. @luciadehoyos.bsky.social @mpi-nl.bsky.social @eagle-genetics.bsky.social @r2d2mh.bsky.social doi.org/10.1038/s415...
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Beate St Pourcain @bstpourcain.bsky.social · 21/09/2026
We introduced the concept of polygenic accuracy to evaluate how well polygenic scores detect social context. @luciadehoyos.bsky.social @mpi-nl.bsky.social @r2d2mh.bsky.social @eagle-genetics.bsky.social doi.org/10.1038/s415...
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Beate St Pourcain @bstpourcain.bsky.social · 21/09/2026
We identified six genomic regions associated with social behaviour, including signals within the CADM2 gene, and found evidence that genetic associations differed by context. doi.org/10.1038/s415... @luciadehoyos.bsky.social @mpi-nl.bsky.social @r2d2mh.bsky.social @eagle-genetics.bsky.social
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Beate St Pourcain @bstpourcain.bsky.social · 21/09/2026
Our new Nature Human Behaviour study uses genome-wide meta-regression across nearly 500,000 social-behavioural observations from more than 73,000 people aged 2–29. Genetic associations differed by behaviour, reporter and age. doi.org/10.1038/s415... @eagle-genetics.bsky.social @r2d2mh.bsky.social
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Beate St Pourcain @bstpourcain.bsky.social · 21/09/2026
Context matters: our new genome-wide meta-regression analysis of social behaviour Context (social domains, age, raters) is not noise! Very proud of our new work. Thank you to: @luciadehoyos.bsky.social @mpi-nl.bsky.social @eagle-genetics.bsky.social @r2d2mh.bsky.social doi.org/10.1038/s415...
doi.org
Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach - Nature Human Behaviour
A genome-wide meta-regression analysis of social behaviour studying ~500,000 observations from ~70,000 individuals, modelling context-specific SNP variation as explained by social domains, informants ...
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Beate St Pourcain @bstpourcain.bsky.social · 16/09/2025
Our work on genetic links across infant motor behaviour, self-care/symbolic actions, and emerging language abilities has been published, with first author @everhoef.bsky.social ! doi.org/10.1111/jcpp... Developing language within a developing body! @mpi-nl.bsky.social
doi.org
<em>Journal of Child Psychology and Psychiatry</em> | ACAMH Pediatric Journal | Wiley Online Library
Background Mastering gross motor abilities in early infancy and culturally defined actions (e.g. self-care routines) in late infancy can initiate cascading developmental changes that affect language...
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Beate St Pourcain @bstpourcain.bsky.social · 08/09/2025
As part of our meta-regression GWAS (preprint doi.org/10.1101/2025...), our PGS predict variation in social context, across outcomes, informants, and, largely, developmental stages, allowing for contextual correlations screens, giving new insight into shared trajectories with mental health.
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Beate St Pourcain @bstpourcain.bsky.social · 08/09/2025
The strongest signal found within our social behaviour meta-regression GWAS (doi.org/10.1101/2025...) resided within the CADM2 gene, associated with self-reported (low) prosocial behaviour at ages 9-14 years.
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Beate St Pourcain @bstpourcain.bsky.social · 08/09/2025
Our genome-wide meta-regression of social behaviour is out as a preprint! www.biorxiv.org/content/10.1... Wonderful @eagle-genetics.bsky.social work with first author @luciadehoyos.bsky.social! We model and predict genetic variation according to social context: outcomes, informants and age!
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Beate St Pourcain @bstpourcain.bsky.social · 03/07/2025
We show that preschool musicality is related to school-age speech-related communication and is partially captured by PGS for rhythmicity. Without claiming causality, the identified links are directionally consistent with development and unrelated to cognition/proxies of EA.
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Beate St Pourcain @bstpourcain.bsky.social · 03/07/2025
It was such fun work @luciadehoyos.bsky.social, Ellen Verhoef, ‪@aysuo.bsky.social‬, Janne Vermeulen, Celeste Figaroa, @profsimonfisher.bsky.social, Reyna Gordon and @miriamlense.bsky.social‬! Thanks for your thoughts and contributions!
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Beate St Pourcain @bstpourcain.bsky.social · 03/07/2025
Just out: “Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity.” doi.org/10.1038/s41539-025-00329-y Big thanks to the first author, amazing @luciadehoyos.bsky.social, and all our co-authors! @mpi-nl.bsky.social
doi.org
Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity - npj Science of Learning
npj Science of Learning - Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity
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Beate St Pourcain @bstpourcain.bsky.social · 18/02/2025
I am absolutely delighted to work together with @yanlinzhou.bsky.social at @mpi-nl.bsky.social as part of her MSCA award, extending collaborations with dieterwolke.bsky.social, @warwicklng.bsky.social and @R2D2mh. Congratulations on your award, Yanlin!
dieterwolke.bsky.social
dieterwolke.bsky.social
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Reposted by Beate St Pourcain
FinnGen @finngen.bsky.social · 05/12/2024
Million Veteran Program & FinnGen teams are pleased to release v1 meta-analysis of MVP, FinnGen and UKBB GWAS data. This first version includes ~300 binary disease definitions across >1.5 M individuals. Browse scans at: mvp-ukbb.finngen.fi
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Beate St Pourcain @bstpourcain.bsky.social · 24/10/2024
Please join us today for our recorded webinar at adhdeurope.eu "Deciphering genetic links between early language abilities & ADHD" at 15.00 CET! www.youtube.com/watch?v=YxT1... Ellen Verhoef and I will discuss our recently published @eagle-genetics.bsky.social work! tinyurl.com/yx5jht2y
youtube.com
Deciphering genetic links between early language abilities & ADHD
YouTube video by Broadcasting ADHD Europe
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Beate St Pourcain @bstpourcain.bsky.social · 20/09/2024
www.themarginalian.org/2014/03/28/d... I wish we could say this one day about peer review.
themarginalian.org
How to Criticize with Kindness: Philosopher Daniel Dennett on the Four Steps to Arguing Intelligently
“Just how charitable are you supposed to be when criticizing the views of an opponent?”
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Beate St Pourcain @bstpourcain.bsky.social · 11/07/2024
I am so proud of my PhD student @luciadehoyos.bsky.social at the Max Planck Institute for Psycholinguistics NL, who won the Outstanding Associate Member Oral Presentation Award #BGA2024 for her work on the social behaviour meta-GWAS in the @eagle-genetics.bsky.social consortium
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Beate St Pourcain @bstpourcain.bsky.social · 17/04/2024
Fancy working with us on the genetics (epigenetics) of early language development and social abilities? We have an open 4-year, fully funded PhD position starting 1 October 2024: www.mpi.nl/career-educa...
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Beate St Pourcain @bstpourcain.bsky.social · 13/03/2024
We are depositing the meta-GWAS summary statistics of early vocabulary size into The Language Archive (TLA) and hope they will spark future research. www.biologicalpsychiatryjournal.com/article/S000...   t.co/5f0SFNf0mb
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Beate St Pourcain @bstpourcain.bsky.social · 27/02/2024
Our SFARI-funded work “Structural models of genome-wide covariance identify multiple common dimensions in autism” is just out in Nat Commun! Congratulations to the first author @luciadehoyos.bsky.social, THANK YOU to all co-authors, participants and @simonsfoundation.org! tinyurl.com/yuy6465x
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Beate St Pourcain @bstpourcain.bsky.social · 19/02/2024
Our study identified genetic associations between children’s early vocabulary size and later-life ADHD, literacy, and general cognition. However, these associations changed dynamically across the first three years of life. tinyurl.com/bdzxbxv8
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Beate St Pourcain @bstpourcain.bsky.social · 19/02/2024
Wonderful news! Our work @MPI_NL showing that infant/toddler vocabulary size is genetically linked to ADHD, literacy, and cognition has been published in Biol Psychiatry tinyurl.com/bdzxbxv8 Big THANK YOU to #EAGLE_GENETICS co-authors & cohorts and first author Ellen Verhoef
tinyurl.com
Genome-wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits
The number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta...
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Beate St Pourcain @bstpourcain.bsky.social · 18/01/2024
We are looking for a new team member interested in ASD and quantitative genetics to join our group as part of the R2D2 project. We will combine analyses on social behaviour within the EAGLE consortium with studies of ASD in SPARK. Interested? Have a look here:
tinyurl.com
Postdoctoral Research Scientist Position in Statistical Genomics/Genetic Epidemiology | Max Planck I...
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Beate St Pourcain @bstpourcain.bsky.social · 09/10/2023
On my way to #WCPG2023; really looking forward to it!
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Beate St Pourcain @bstpourcain.bsky.social · 03/10/2023
Everytime I come back here my mind unfolds ... my mental garden
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Beate St Pourcain @bstpourcain.bsky.social · 02/10/2023
We have an upcoming PostDoc position in Statistical Genomics within my group at @MPI_NL as part of the EU-funded @R2d2Mh project. Interested in modelling the genomic influences underlying social behaviour in ASD? tinyurl.com/3w8k8ph7
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Beate St Pourcain @bstpourcain.bsky.social · 30/09/2023
Slowly diving into the deep blue sky. Glad to be on the other side and finding some familiar faces...
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