Les partenaires se ressemblent davantage que ce que le hasard présagerait, ce qui laisse des traces dans le génome de leurs enfants. Des scientifiques de l’Unil ont développé une nouvelle méthode perm...

A tool for sniffing out the differences in vari-Ants - PacificBiosciences/aardvark

Traits such as height, metabolism, and disease risk can be affected differently – and even in opposite directions – depending on whether the genetic variant responsible is inherited from the mothe...

A novel multistep strategy reveals how parent-of-origin effects shape complex traits in large-scale biobanks.

A novel multistep strategy reveals how parent-of-origin effects shape complex traits in large-scale biobanks.

The authors found, after analyzing 10,960 individuals from 9 multiancestry biobanks across 6 countries, that genetic factors previously associated with BMI have limited impact on GLP-1 receptor agonis...

Biobank data are extensively used. Schoeler and colleagues show that self-report inaccuracy and selective participation are sources of poor reproducibility for biobank-scale research.

Parent-of-origin effects (POEs) occur when the impact of a genetic variant depends on its parental origin. Traditionally linked to genomic imprinting, these effects are believed to have evolved from p...