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Mathew Summers

@summersathome.bsky.social
218 followers 333 following 40 posts

Thalamic hodologist, formerly retina surfer. Scientist @AllenInstitute

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Mathew Summers @summersathome.bsky.social · 16/09/2026
Busy day - our work on the organization of norepinephrine neurons in the locus coeruleus is out today in Nature too. If you're interested in digging deeper, the data and analyses supporting all of our work is hosted in a public CodeOcean collection: codeocean.allenneuraldynamics.org/collections/...
codeocean.allenneuraldynamics.org
Code Ocean
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Mathew Summers @summersathome.bsky.social · 16/09/2026
Proud to announce our latest preprint introducing 3D-MAESTRO: an automated pipeline that makes processing volumetric imaging data routine and reproducible. Out now on BioRxiv: www.biorxiv.org/content/10.6...
biorxiv.org
3D-MAESTRO: A scalable, modular, portable pipeline for automated processing of large-scale volumetric brain microscopy data
Light microscopy is routinely used to explore the cellular and molecular structure of tissues, but the scale and complexity of data remains a bottleneck for discovery. We introduce 3D-MAESTRO (3D-Micr...
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Fix the L8 @fixthel8.bsky.social · 17/08/2026
Bus lanes on Denny are getting painted THIS WEEKEND! Join us and Mayor Wilson to celebrate with another Race the L8 on Tuesday, September 8th at 5 PM at Denny Park! Lets prove that she Fixed the L8 and that it's finally faster than walking!
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Mathew Summers @summersathome.bsky.social · 08/08/2026
Cool work! www.nature.com/articles/s41...
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Mathew Summers @summersathome.bsky.social · 13/04/2026
Check out our latest work on the structure and function of locus coeruleus (LC)! My own contribution to this project was investigating the anatomical projections of individually reconstructed LC neurons from our ExA-SPIM pipeline (see: elifesciences.org/reviewed-pre...). A few more notes:
elifesciences.org
Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues
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Mathew Summers @summersathome.bsky.social · 18/02/2026
All the more reason to be excited by the latest generation of glutamate indicators: www.nature.com/articles/s41...
nature.com
Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...
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Andrew Straw @andrewstraw.bsky.social · 16/02/2026
Using our bee-tracking drone, we discovered that honey bees 🐝 have highly precise and individual routes. Now published at @currentbiology.bsky.social : doi.org/10.1016/j.cu...
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Mathew Summers @summersathome.bsky.social · 06/02/2026
Retinal waves are known to be important for proper wiring at the retina's downstream targets: but their role in the development of microcircuits -within the retina itself- is less understood. Some nice work on this topic by @miah-pitcher.bsky.social!
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Annie G. Bryant @anniegbryant.bsky.social · 27/01/2026
The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...
Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.
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Mathew Summers @summersathome.bsky.social · 08/01/2026
We've got a great lineup of speakers for our Thalamocortical Interactions GRS! Only a few spots remaining for poster presenters - apply soon!
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adamezracohen.bsky.social @adamezracohen.bsky.social · 04/01/2026
What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
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Ben Sivyer @bensivyer.bsky.social · 04/11/2025
We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy.
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John Ball @john-m-ball.bsky.social · 03/12/2025
Extremely proud to share our publication on S-cone circuitry in the ground squirrel, newly available this week in PNAS. We've been staring at these reconstructions for a long time, and I'm excited for others to see the results. 1/n www.pnas.org/doi/10.1073/...
pnas.org
S-cone-specific circuitry in the outer plexiform layer of a cone-dominant mammal | PNAS
In the vertebrate retina, short wavelength-sensitive S-cones and their downstream interneurons play unique roles in both image forming and non-imag...
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Mathew Summers @summersathome.bsky.social · 16/11/2025
Come check out my poster this morning (FF9) to learn about thalamic innervation of frontal cortex! We've got a lot of cool data for ya #sfn2025 #sfn25
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Matteo Carandini @carandinilab.net · 12/11/2025
Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here: www.ucl.ac.uk/cortexlab/po...
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Mathew Summers @summersathome.bsky.social · 06/11/2025
10 days left to be considered for a speaking slot at the Thalamocortical Interactions GRS! If you're a trainee at the NIH and unable to submit an application due to furlough, shoot me a DM and we'll figure something out.
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Washington State Democrats @wadems.org · 03/11/2025
Can’t always trust everyone. Drop your ballot in an official drop box, not in someone’s hands. To find your nearest drop box, visit: www.sos.wa.gov/elections/vo...
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Kevin Bender @neurobender.bsky.social · 15/10/2025
Fresh off the press! @selinsch.bsky.social discovered some really cool features of mouse frontal cortex pyramidal cells that co-vary with dopamine receptor expression. D3R+ cells appear very responsive to AP bursts, producing Ca transients across dendritic arbors. www.jneurosci.org/content/earl...
jneurosci.org
Intrinsic dendritic integration features of prefrontal layer 5 pyramidal cell subclasses
Prefrontal cortex (PFC) is an associative center in the brain and integrates various inputs to support cognition. Layer 5 pyramidal cells are themselves associative centers, as their dendrites span al...
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BWJones @bwjones.bsky.social · 09/10/2025
YEEEEEAAAAAAAHHHH, Teresa!!!
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The Transmitter @thetransmitter.bsky.social · 07/10/2025
To celebrate the first anniversary of the release of FlyWire, we asked nine neuroscientists to share how they are using connectome data in their research and what they hope is in store for the future of fly connectomics. By @franciscorr25.bsky.social #neuroskyence bit.ly/3Wx5nt3
bit.ly
How FlyWire is redefining Drosophila research, one year in
Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.
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Congresswoman Pramila Jayapal @jayapal.house.gov · 06/10/2025
A huge congrats to Seattle scientist Mary E. Brunkow for winning the Nobel Prize in medicine! This is exactly the kind of groundbreaking work that we should be leading on — and it’s exactly why I’ll continue to fight Trump’s cuts to the NIH and research. www.seattletimes.com/seattle-news...
seattletimes.com
A Seattle scientist won a Nobel Prize. She thought the call was spam
Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance.
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Mathew Summers @summersathome.bsky.social · 03/10/2025
Check out our resource for navigating and analyzing spatial transcriptomics data in the thalamus, which we fondly call "the THALMANAC" (𝐓𝐇𝐀𝐋amus 𝐌ERFISH 𝐀𝐍alysis and 𝐀𝐂cess), now live on bioRxiv: www.biorxiv.org/content/10.1...
biorxiv.org
Exploring the correspondence between gene expression and thalamic nuclei using the THALMANAC resource
The thalamus connects the sensory organs and major subcortical brain regions with the neocortex. The thalamus has long been divided into multiple discrete nuclei, based on cytoarchitecture, histochemi...
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Mathew Summers @summersathome.bsky.social · 10/09/2025
If you're a trainee studying the thalamus, consider checking out our GRS on Thalamocortical Networks in Sensation, Behavior, and Disease: www.grc.org/thalamocorti.... Apply by Nov 16th to be considered for a talk!
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Nigel Goldenfeld @nigelgoldenfeld.bsky.social · 29/08/2025
Very few PhD students finish within 4 years. But international students will need to do that if US proposed visa rules change go through. Sound reasonable to you? Fed register is accepting comments for next month. Details at the link & comment button www.federalregister.gov/documents/20...
federalregister.gov
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
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Dr. Lucky Tran @luckytran.com · 22/08/2025
The ideological cancellation of $800 million of scientific research grants because they supposedly focused on DEI was just backed by the Supreme Court. This is horrific on so many levels.
npr.org
Supreme Court allows NIH to stop making nearly $800M in research grants for now
But the court, in its emergency docket order, also left in place by a 5-4 order a lower court ruling that threw out NIH memos that enforced the administration's policies.
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Mathew Summers @summersathome.bsky.social · 20/08/2025
A great environment!
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RoordaLab @roordalab.bsky.social · 17/07/2025
6+6 = 12 reasons to move to Waterloo, Canada. First 6..... 6 job openings in the University of Waterloo School of Optometry & Vision Science/Waterloo Eye Institute. lnkd.in/d3QD5wFA see thread for the next 6.
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Max Kozlov @maxkozlov.bsky.social · 15/07/2025
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding. NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
nature.com
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
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Chuck Taylor | Seattle @chcktylr.bsky.social · 15/07/2025
CCTV comes to Seattle.
seattletimes.com
Seattle police cameras, now up and running, draw constitutional concerns
Seattle's newly revamped Real Time Crime Center is operational, with analysts monitoring dozens of surveillance cameras placed in areas with high crime rates.
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Ryan Packer @typewriteralley.bsky.social · 11/07/2025
This is amazing. The momentum to fix the 8 is UNPRECEDENTED!
Crowd waiting to race the 8
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Alex Long @alexandralong.bsky.social · 10/07/2025
Really important article in the NY Times today about cuts to NIH diversity grants, featuring a profile of Ashley Albright @aralbright.bsky.social who is an amazing and super inspiring cell biology postdoc whose K99 was prematurely terminated.
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Eric Topol @erictopol.bsky.social · 06/07/2025
Summary Table of the massive defunding of biomedical research in the United States www.nytimes.com/interactive/...
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Michael Buice @mabuice.bsky.social · 03/07/2025
The ICE budget is now set to be approximately what the NIH budget was. We’re shifting money from solving real problems to solving fictitious problems.
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Berkeleyside @berkeleyside.org · 03/07/2025
It's been a fixture of downtown for 20 years. It’s the second big Berkeley bookstore closure this year.
berkeleyside.org
Half Price Books will close its downtown Berkeley store after 20 years
It's been a fixture of downtown for 20 years. It’s the second big Berkeley bookstore closure this year.
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Joshua Weitz @joshuasweitz.bsky.social · 30/06/2025
Part 2 - Slashing budgets of NIH, NASA, NSF (and NOAA, DOE, EPA and ...) undermines key employers in communities all across the US that form hubs of research and technology development. For NIH alone, we estimate $46B in economic loss and 202K lost jobs. scienceimpacts.org/fy26
scienceimpacts.org
SCIMaP - Impacts of Federal Cuts to Science and Medical Research
View Projected Impact of the FY2026 Budget Cuts to the NIH
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Mack Butterfield @mack2114.bsky.social · 13/06/2025
More Americans voted for Senator Alex Padilla than for 48 of the 53 red state GOP U.S. Senators combined. That alone makes him a powerful senator.
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actioncookbook @actioncookbook.com · 05/06/2025
ME: two of my most hated enemies are going to drag each other down YOU: right, the Trump-Musk thing ME: the what
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Sen. Pumpkin Gogurt @ugarles.bsky.social · 05/06/2025
why not decommission it the usual way: launching it into a million pieces over protected wetlands
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Michael Battalio @battalio.com · 31/05/2025
The President's Budget request as released yesterday will gut scientific research. Why should you care? 1) Science is fundamentally a jobs program. Many 100,000s are employed to do science and work for you, the US taxpayer.
NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.
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Gregg Gonsalves @gregggonsalves.bsky.social · 26/05/2025
I subscribe to the @newyorker.com, I was part of ACT UP, I knew Larry Kramer well and know Tony Fauci too. Daniel Immerwahr's piece on RFKJr, features this and other passages that need a reponse. 1/
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Markus Meister @mameister4.bsky.social · 21/05/2025
If you're planning a course with mathematical methods content, or use such methods in your own work, please take a look at "Mathematics in Biology", by Meister, Lee, and Portugues, published at MIT Press. 1/2 @portugueslab.bsky.social mitpress.mit.edu/978026204940...
mitpress.mit.edu
Mathematics in Biology
Biology has turned into a quantitative science. The core problems in the life sciences today involve complex systems that require mathematical expression, ye...
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David Mouritsen @davidmouritsen.bsky.social · 10/05/2025
On the NSF's 75th: “‘NSF investments have driven groundbreaking innovations, from the internet and LASIK eye surgery to the first image of a black hole... The foundation has also played a key role in the work of 268 Nobel Prize laureates, helping to shape many of their landmark achievements.’”
joshuasweitz.substack.com
Time to Save the National Science Foundation, 75 Years and Thriving
The National Science Foundation marks its 75th anniversary today, May 10th 2025. Rather than celebrate, it's time to save it.
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Mathew Summers @summersathome.bsky.social · 15/04/2025
Check out some of our locus coeruleus reconstructions - the average fully reconstructed LC neuron is about 30 cm in length (in a mouse brain that spans ~1.3 cm front to back)
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Ken Jennings @kenjennings.bsky.social · 13/04/2025
Jeopardy! is great, but my real passion… Seattle-area local transit.
m.youtube.com
The Transit Effect With Ken Jennings - Ep. 1: The History of Transit
YouTube video by Community Transit
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Rose Z. Hill, Ph.D. @rose-hill.bsky.social · 09/01/2025
My group is hiring at Oregon Health & Science University. Come work with us in beautiful Portland to study interoception and physiology. Check out the lab view! 🌲👩‍🔬 Research Assistant 2: externalcareers-ohsu.icims.com/jobs/32602/r... Postdoc applicants: please email me your CV and 3-4 references.
View of Portland from Marquam Hill campus at OHSU
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Mina Kimes @minakimes.bsky.social · 08/03/2025
The Seahawks just ruined my day
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Ardem Patapoutian @ardemp.bskyverified.social · 05/03/2025
That’s special! Check out that photo of four generations of scientists coming together for a panel discussion: Thorsten trained Carla, who trained Marla, who trained Anna.
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Celeste Ng @pronounced-ing.bsky.social · 30/01/2025
Okay, I cannot recommend 5calls.org enough. Enter your address and it will find all your reps (federal and state). AND give you a list of issues to call about AND which reps to call about each of them AND a little script for each, in case it's helpful. They have an app, too.
5calls.org
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
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Congresswoman Pramila Jayapal @jayapal.house.gov · 28/01/2025
Washington parents are calling my office, worried that school lunch programs will be frozen and that their kids will come home hungry tomorrow. That’s President Trump’s doing. Thanks to him, families are scared their children won’t have lunch. Reverse the funding freeze.
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Nancy Kanwisher @nancykanwisher.bsky.social · 28/01/2025
Academic workers across the country are organizing to call on our congressional representatives on Thursday, 1/30, at 3pm ET / 12pm PT to demand these restrictions be lifted immediately. There will be a training over zoom at the beginning of the event. Join us! form.jotform.com/250226137228...
form.jotform.com
Join researchers across the country in fighting restrictions on the NIH
Please click the link to complete this form.
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