Sign in

Stephan Wilmes

@stephanwilmes.bsky.social
99 followers 272 following 9 posts

Looking into regulators of Rab GTPase activity. Postdoc in Martin Loose's Lab at ISTA, former PhD student in Daniel Kümmel's Lab at the University of Münster.

PostsRepliesMedia
Reposted by Stephan Wilmes
Pavel Barahtjan @pavelbarahtjan.bsky.social · 23/01/2026
We have several Master’s thesis projects available in the D’Angelo lab, spanning different areas of lipid biology/biochemistry. If you know someone who might be interested, we’d really appreciate you sharing this. #lipidtime www.epfl.ch/labs/dangelo...
epfl.ch
Master Projects
DANGELOLAB
078
Reposted by Stephan Wilmes
Maria Bohnert Lab @bohnertlab.bsky.social · 07/11/2025
Proud to share our study on #LipidDroplet #Motility #Mitochondria #MembraneContactSite now in Cell Reports @cp-cellreports.bsky.social! Big thanks to @rwedlichsoldner.bsky.social, @flofroehlich.bsky.social, @ruferbus.bsky.social, Daniel Kümmel lab, Thomas Becker lab! www.cell.com/cell-reports...
cell.com
The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility
Zhao et al. identify the molecular machinery for lipid droplet motility, consisting of the type V myosin Myo2, the Myo2 adaptor protein Ldm1, and its surface receptor Ldo16. They uncover a molecular l...
43412
Reposted by Stephan Wilmes
Holthuis Lab @holthuislab.bsky.social · 17/10/2025
🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...
01212
Stephan Wilmes @stephanwilmes.bsky.social · 02/09/2025
Thrilled to share our newest publication in Science Advances! We uncovered how two RabGEF complexes — Mon1-Ccz1 and Fuzzy-Inturned — adapt to regulate distinct Rab GTPases despite their structurally conserved catalytic core. www.science.org/doi/full/10....
science.org
Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned
The molecular comparison of related RabGEFs reveals adaptation mechanisms of a functional module for specific cellular tasks.
284
Reposted by Stephan Wilmes
Jan-Hannes Schaefer @jhschaef.bsky.social · 01/08/2025
Check out our new preprint from the @landerlab.bsky.social, Stagg-Lab and Cianfrocco-Lab: CryoSift - An accessible and automated CNN-driven tool for cryo-EM 2D class selection www.biorxiv.org/content/10.1... Happy testing: cryosift.org #cryoEM #CNN
CryoSift – An accessible and automated CNN-driven
tool for cryo-EM 2D class selection
1177
Stephan Wilmes @stephanwilmes.bsky.social · 06/04/2025
Happy our preprint on the RabGEFs Mon1-Ccz1 and Fuzzy-Inturned is out! doi.org/10.1101/2025... Thanks to everyone involved! @jessetoenjes.bsky.social @jhschaef.bsky.social @djanuliene.bsky.social @arnemoeller.bsky.social @nartimsoole.bsky.social
doi.org
Mechanistic Plasticity of the RabGEFs Mon1-Ccz1 and Fuzzy-Inturned
Rab GTPases organize intracellular trafficking and provide identity to organelles. Their spatiotemporal activation by guanine nucleotide exchange factors (GEFs) is tightly controlled to ensure fidelit...
040
Reposted by Stephan Wilmes
bioRxivpreprint @biorxivpreprint.bsky.social · 29/03/2025
Mechanistic Plasticity of the RabGEFs Mon1-Ccz1 and Fuzzy-Inturned www.biorxiv.org/content/10.1101/202…
053
Reposted by Stephan Wilmes
bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 26/11/2024
Structure and mechanism of the RalGAP tumor suppressor complex www.biorxiv.org/content/10.1101/202…
biorxiv.org
Structure and mechanism of the RalGAP tumor suppressor complex https://www.biorxiv.org/content/10.1101/2024.11.25.625123v1
The RalGAP (GTPase activating protein) complexes are negative regulators of the Ral GTPases and thus
031