Reposted by Sreeparna PradhanGaspar Jekely @jekely.biologists.social.ap.brid.gy · 15/10/2026Here is our new collaborative paper on the origin of cholinergic and monoaminergic signaling. The data suggest that biogenic amine signaling is thus not a bilaterian innovation but an ancient mode of cellular communication that evolved from generalist to […] [Original post on biologists.social] 03922
Reposted by Sreeparna PradhanJakob Voigts @jvoigts.bsky.social · 11/10/2026How do 🐁deal with complex landscapes? Turns out they learn a lot very quickly. We think they do this by learning a set of repeated sparse paths, which form a type of compressed world model. Joint work with the Hermundstad lab, led by Tzuhsuan Ma and Alison Comrie: www.biorxiv.org/content/10.6... 214258
Reposted by Sreeparna PradhanRoxana Zeraati @roxana-zeraati.bsky.social · 08/10/2026Re-post 🔁 is appreciated! #neurojobs: we’re looking for new team members to join us @cmc-unit.bsky.social! If you’d like to study decision-making in naturalistic & embodied contexts (integrating RL, RNNs & cross-species data analysis) in a cool & collaborative research environment 😎, check 👇 02217
Reposted by Sreeparna PradhanSweta Agrawal @hokuba.bsky.social · 16/09/2026The Agrawal lab has published its first paper! "Sticking the landing: leg mechanosensory feedback coordinates the transition from flight to landing" www.biorxiv.org/content/10.6... This project was led by a technician in the lab, Tse-Wei (Wayne) Kuo. Brief 🧵on what we foundagrawal-lab-workspace.slack.comSlack 88328
Sreeparna Pradhan @sreeparnap.bsky.social · 16/09/2026Very cool! Looking forward to reading! Congratulations :) 010
Reposted by Sreeparna PradhanMisha Ahrens @mishaahrens.bsky.social · 09/09/2026Whole-body cellular activity imaging in zebrafish, headed by Virginie Ruetten @vmsruetten.bsky.social - new paper is out: www.nature.com/articles/s41...nature.comImaging cellular activity across all organs reveals body-wide circuits - NatureAn imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits. 110441
Reposted by Sreeparna PradhanZooCELL MSCA-Doctoral Network @zoocell.bsky.social · 21/07/20265️⃣ What do you wish more people knew about science? "I wish more people would come to the lab and look down a microscope. Science starts with fascination, followed by questions." 0103
Reposted by Sreeparna PradhanBen Hayden @benhayden.bsky.social · 16/07/2026And, of course, Eb Fetz was the prophet of this whole direction, with this paper from 1992, but that reads like it was written 30 years later: depts.washington.edu/fetzweb/asse...depts.washington.edu 1152
Reposted by Sreeparna PradhanKevin Mitchell @wiringthebrain.bsky.social · 13/05/2026All neuromodulators are more spatially and temporally specific than was often believed! 0112
Sreeparna Pradhan @sreeparnap.bsky.social · 12/05/2026Congratulations @natashamhatre.bsky.social 🎉 130
Sreeparna Pradhan @sreeparnap.bsky.social · 09/05/2026Congratulations! Looking forward to reading this :) 110
Sreeparna Pradhan @sreeparnap.bsky.social · 07/05/2026Many congratulations, @arkarupbanerjee.bsky.social 🎉 010
Reposted by Sreeparna PradhanThe Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 20/04/2026How neurons sense bacteria in the gut: To understsand the mechanisms that enable the bacterial microbiome to influence brain function, a new study examines the mechanisms at work in a model “bacterial specialist,” C. elegans. picower.mit.edu/news/how-neu... #neuroscience @mitbcs.bsky.social 242
Sreeparna Pradhan @sreeparnap.bsky.social · 10/04/2026A detailed mapping of olfactory navigation. Pleased to have contributed to this landmark study led by Talya Kramer! 030
Reposted by Sreeparna PradhanThe Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 10/04/2026How do nervous systems produce behaviors? A new MIT study provides a detailed mechanistic mapping of exactly what happens in the brains of C. elegans worms when they “follow their nose” to savor attractive odors or avoid unappealing ones. picower.mit.edu/news/navigat... #neuroscience 1104
Reposted by Sreeparna PradhanPiali Sengupta @senguptalab.bsky.social · 01/04/2026Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress. rdcu.be/fbd4ardcu.beAn enteric neuron ionotropic receptor regulates salt stress resistanceNature - The I3 pharyngeal enteric neuron in Caenorhabditis elegans detects high-salt conditions, and the GLR-9 ionotropic salt receptor expressed specifically in I3 regulates genes related to salt... 108021
Sreeparna Pradhan @sreeparnap.bsky.social · 19/03/2026Very cool study! Looking forward to reading in detail. Congratulations @hannah-haberkern.bsky.social and authors!🎉 200
Reposted by Sreeparna PradhanHannah Haberkern @hannah-haberkern.bsky.social · 19/03/2026How does an animal choose between exploring for a better food source and taking advantage of a known one? Our recent work in Current Biology demonstrates how recent feeding and metabolic state dynamically influence fly local search. bit.ly/3PfrIv3 #Science #Neurosky #Foraging #Drosophila 313549
Reposted by Sreeparna PradhanBratislav Misic @misicbata.bsky.social · 17/03/2026Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️ 13919
Sreeparna Pradhan @sreeparnap.bsky.social · 12/03/2026The MIT BCS Postdoc Association is looking for a Rising Star 🌟 Showcase your work and meet folks in the department! Deadline 31st May 2026! @picowerinstitute.bsky.social 043
Sreeparna Pradhan @sreeparnap.bsky.social · 25/02/2026So well deserved @irinakitop.bsky.social! Many congratulations 🎉 110
Reposted by Sreeparna PradhanPiali Sengupta @senguptalab.bsky.social · 28/01/2026Our first 2026 paper is out @currentbiology.bsky.social! 👏 to @nathancsharris.bsky.social (now Asst Prof, GA State) and PD Priya Dutta. Here we show how transcriptional and trafficking pathways coordinate thermoreceptor levels to precisely modulate response plasticity www.cell.com/current-biol...cell.comExperience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticityHarris, Dutta, et al. find that experience-dependent plasticity in the activation threshold of the AFD thermosensory neurons is mediated by modulating warm and cold thermoreceptor levels at the sensor... 55621
Reposted by Sreeparna PradhanMarianne Roca @marianneroca.bsky.social · 28/01/2026How does a predator sense its prey? 🪱The nematode Pristionchus pacificus preys on other nematodes, but how it detects them in its environment? That is what we have been exploring : www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 3217
Sreeparna Pradhan @sreeparnap.bsky.social · 28/01/2026Congratulations! 🎉 Looking forward to reading in detail. 110
Reposted by Sreeparna PradhanJavier Apfeld @javierapfeld.bsky.social · 28/01/2026Friends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/ 78631
Reposted by Sreeparna PradhanJames Lightfoot @jameslightfoot.bsky.social · 21/01/2026Why do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.nature.comPredatory aggression evolved through adaptations to noradrenergic circuits - NatureNoradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp... 98035
Reposted by Sreeparna PradhanAlejandro Aballay, PhD @aaballay.bsky.social · 02/01/2026Circadian timing shapes infection outcomes. In our new paper, we show that baseline inflammatory state—measurable before infection—strongly predicts which individuals will survive a bacterial challenge. www.science.org/doi/10.1126/...science.orgCircadian-shaped immune variability predicts infection outcomeBasal immune state under circadian control predicts infection outcome, and clock gene perturbation shifts survival patterns. 0134
Reposted by Sreeparna PradhanMackenzie Weygandt Mathis @trackingactions.bsky.social · 31/12/2025Interested in the latest advances in neuroscience (neural dynamics and internal models) and how they can be leveraged to build smarter, adaptive AI? ➡️ My first real solo piece 🖤🫶 @natneuro.nature.com rdcu.be/eWVmArdcu.beLeveraging insights from neuroscience to build adaptive artificial intelligenceNature Neuroscience - Adaptive intelligence envisions AI that, like animals, learns online, generalizes and adapts quickly. This Perspective reviews biological foundations, progress in AI and... 512535
Sreeparna Pradhan @sreeparnap.bsky.social · 31/12/2025Moments that brought joy in this otherwise rollercoaster of a year. All spotted in the greater Boston area. 110
Reposted by Sreeparna PradhanJan M. Ache @jan-ache.bsky.social · 19/12/2025How do animals channel sensory information into motor pathways to generate flexible behavioral output? Excited to share a new preprint addressing this question by leveraging the new #maleCNS connectome, behavioral experiments, and in-vivo recordings: doi.org/10.64898/202.... A long🧵... 37029
Sreeparna Pradhan @sreeparnap.bsky.social · 26/11/2025Very cool findings! Looking forward to reading in detail! 010
Reposted by Sreeparna PradhanCarlos Ribeiro @ribeirocarlitos.bsky.social · 26/11/2025Thrilled to share our new paper! With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste. Link @nature.com: www.nature.com/articles/s41...nature.comEvolution of taste processing shifts dietary preference - NatureCalcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in addition to p... 916960