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Sreeparna Pradhan

@sreeparnap.bsky.social
846 followers 1.1K following 99 posts

K. Lisa Yang Brain-Body Center Postdoctoral Fellow at Steve Flavell's Lab @Picower Inst, MIT | PhD from Michael Hendricks' Lab @IPN, McGill Univ | Animal behavior | Neuroscience | Open science

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Reposted by Sreeparna Pradhan
Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 15/10/2026
Here is our new collaborative paper on the origin of cholinergic and monoaminergic signaling. The data suggest that biogenic amine signaling is thus not a bilaterian innovation but an ancient mode of cellular communication that evolved from generalist to […] [Original post on biologists.social]
Main biosynthetic pathways of biogenic amines and their evolution. Diagram showing key steps of the main pathways for the production of biogenic amines. The main enzymes that catalyze each reaction are shown, as well as, alternative
enzymes that may promiscuously catalyze the same reaction.
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Reposted by Sreeparna Pradhan
Jakob Voigts @jvoigts.bsky.social · 11/10/2026
How do 🐁deal with complex landscapes? Turns out they learn a lot very quickly. We think they do this by learning a set of repeated sparse paths, which form a type of compressed world model. Joint work with the Hermundstad lab, led by Tzuhsuan Ma and Alison Comrie: www.biorxiv.org/content/10.6...
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Roxana Zeraati @roxana-zeraati.bsky.social · 08/10/2026
Re-post 🔁 is appreciated! #neurojobs: we’re looking for new team members to join us @cmc-unit.bsky.social!
If you’d like to study decision-making in naturalistic & embodied contexts (integrating RL, RNNs & cross-species data analysis) in a cool & collaborative research environment 😎, check 👇
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Sreeparna Pradhan @sreeparnap.bsky.social · 09/10/2026
Congratulations and best wishes!🎉
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Reposted by Sreeparna Pradhan
Sweta Agrawal @hokuba.bsky.social · 16/09/2026
The Agrawal lab has published its first paper! "Sticking the landing: leg mechanosensory feedback coordinates the transition from flight to landing" www.biorxiv.org/content/10.6... This project was led by a technician in the lab, Tse-Wei (Wayne) Kuo. Brief 🧵on what we found
agrawal-lab-workspace.slack.com
Slack
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Sreeparna Pradhan @sreeparnap.bsky.social · 16/09/2026
Very cool! Looking forward to reading! Congratulations :)
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Sreeparna Pradhan @sreeparnap.bsky.social · 09/09/2026
Congratulations! 🎉
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Reposted by Sreeparna Pradhan
Misha Ahrens @mishaahrens.bsky.social · 09/09/2026
Whole-body cellular activity imaging in zebrafish, headed by Virginie Ruetten @vmsruetten.bsky.social - new paper is out: www.nature.com/articles/s41...
nature.com
Imaging cellular activity across all organs reveals body-wide circuits - Nature
An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.
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Reposted by Sreeparna Pradhan
ZooCELL MSCA-Doctoral Network @zoocell.bsky.social · 21/07/2026
5️⃣ What do you wish more people knew about science? "I wish more people would come to the lab and look down a microscope. Science starts with fascination, followed by questions."
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Reposted by Sreeparna Pradhan
Ben Hayden @benhayden.bsky.social · 16/07/2026
And, of course, Eb Fetz was the prophet of this whole direction, with this paper from 1992, but that reads like it was written 30 years later: depts.washington.edu/fetzweb/asse...
depts.washington.edu
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Sreeparna Pradhan @sreeparnap.bsky.social · 19/06/2026
It's such a special place!
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Sreeparna Pradhan @sreeparnap.bsky.social · 21/05/2026
Many congratulations 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 20/05/2026
Huge congratulations 🎉
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Kevin Mitchell @wiringthebrain.bsky.social · 13/05/2026
All neuromodulators are more spatially and temporally specific than was often believed!
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Sreeparna Pradhan @sreeparnap.bsky.social · 12/05/2026
Congratulations @natashamhatre.bsky.social 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 09/05/2026
Congratulations! Looking forward to reading this :)
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Sreeparna Pradhan @sreeparnap.bsky.social · 07/05/2026
Many congratulations, @arkarupbanerjee.bsky.social 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 04/05/2026
Congratulations!😊
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The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 20/04/2026
How neurons sense bacteria in the gut: To understsand the mechanisms that enable the bacterial microbiome to influence brain function, a new study examines the mechanisms at work in a model “bacterial specialist,” C. elegans. picower.mit.edu/news/how-neu... #neuroscience @mitbcs.bsky.social
Little worms wriggle through a red-tinted gel.
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Sreeparna Pradhan @sreeparnap.bsky.social · 11/04/2026
It's a beautiful spring morning! #birds
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Sreeparna Pradhan @sreeparnap.bsky.social · 11/04/2026
Early morning meal for this Cooper's hawk
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Sreeparna Pradhan @sreeparnap.bsky.social · 10/04/2026
A detailed mapping of olfactory navigation. Pleased to have contributed to this landmark study led by Talya Kramer!
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The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 10/04/2026
How do nervous systems produce behaviors? A new MIT study provides a detailed mechanistic mapping of exactly what happens in the brains of C. elegans worms when they “follow their nose” to savor attractive odors or avoid unappealing ones. picower.mit.edu/news/navigat... #neuroscience
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Sreeparna Pradhan @sreeparnap.bsky.social · 10/04/2026
Very cool! Congratulations 🎉
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Reposted by Sreeparna Pradhan
Piali Sengupta @senguptalab.bsky.social · 01/04/2026
Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress. rdcu.be/fbd4a
rdcu.be
An enteric neuron ionotropic receptor regulates salt stress resistance
Nature - The I3 pharyngeal enteric neuron in Caenorhabditis elegans detects high-salt conditions, and the GLR-9 ionotropic salt receptor expressed specifically in I3 regulates genes related to salt...
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Sreeparna Pradhan @sreeparnap.bsky.social · 01/04/2026
Many congratulations!🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 19/03/2026
Congratulations @loganjames.bsky.social 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 19/03/2026
Congrats @tararaam.bsky.social 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 19/03/2026
Very cool study! Looking forward to reading in detail. Congratulations @hannah-haberkern.bsky.social and authors!🎉
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Hannah Haberkern @hannah-haberkern.bsky.social · 19/03/2026
How does an animal choose between exploring for a better food source and taking advantage of a known one? Our recent work in Current Biology demonstrates how recent feeding and metabolic state dynamically influence fly local search. bit.ly/3PfrIv3 #Science #Neurosky #Foraging #Drosophila
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Bratislav Misic @misicbata.bsky.social · 17/03/2026
Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️
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Sreeparna Pradhan @sreeparnap.bsky.social · 12/03/2026
The MIT BCS Postdoc Association is looking for a Rising Star 🌟 Showcase your work and meet folks in the department! Deadline 31st May 2026! @picowerinstitute.bsky.social
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Sreeparna Pradhan @sreeparnap.bsky.social · 10/03/2026
Oh I missed this! Many congratulations 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 25/02/2026
So well deserved @irinakitop.bsky.social! Many congratulations 🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 17/02/2026
Congratulations!🎉
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Sreeparna Pradhan @sreeparnap.bsky.social · 29/01/2026
Congratulations to all!
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Reposted by Sreeparna Pradhan
Piali Sengupta @senguptalab.bsky.social · 28/01/2026
Our first 2026 paper is out @currentbiology.bsky.social! 👏 to @nathancsharris.bsky.social (now Asst Prof, GA State) and PD Priya Dutta. Here we show how transcriptional and trafficking pathways coordinate thermoreceptor levels to precisely modulate response plasticity www.cell.com/current-biol...
cell.com
Experience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticity
Harris, Dutta, et al. find that experience-dependent plasticity in the activation threshold of the AFD thermosensory neurons is mediated by modulating warm and cold thermoreceptor levels at the sensor...
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Sreeparna Pradhan @sreeparnap.bsky.social · 28/01/2026
Congratulations!🎉
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Marianne Roca @marianneroca.bsky.social · 28/01/2026
How does a predator sense its prey? 🪱The nematode Pristionchus pacificus preys on other nematodes, but how it detects them in its environment? That is what we have been exploring : www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Sreeparna Pradhan @sreeparnap.bsky.social · 28/01/2026
Congratulations! 🎉 Looking forward to reading in detail.
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Javier Apfeld @javierapfeld.bsky.social · 28/01/2026
Friends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/
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Sreeparna Pradhan @sreeparnap.bsky.social · 21/01/2026
Very cool work! Congratulations all!
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James Lightfoot @jameslightfoot.bsky.social · 21/01/2026
Why do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
nature.com
Predatory aggression evolved through adaptations to noradrenergic circuits - Nature
Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp...
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Alejandro Aballay, PhD @aaballay.bsky.social · 02/01/2026
Circadian timing shapes infection outcomes. In our new paper, we show that baseline inflammatory state—measurable before infection—strongly predicts which individuals will survive a bacterial challenge. www.science.org/doi/10.1126/...
science.org
Circadian-shaped immune variability predicts infection outcome
Basal immune state under circadian control predicts infection outcome, and clock gene perturbation shifts survival patterns.
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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 31/12/2025
Interested in the latest advances in neuroscience (neural dynamics and internal models) and how they can be leveraged to build smarter, adaptive AI? ➡️ My first real solo piece 🖤🫶 @natneuro.nature.com rdcu.be/eWVmA
rdcu.be
Leveraging insights from neuroscience to build adaptive artificial intelligence
Nature Neuroscience - Adaptive intelligence envisions AI that, like animals, learns online, generalizes and adapts quickly. This Perspective reviews biological foundations, progress in AI and...
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Sreeparna Pradhan @sreeparnap.bsky.social · 31/12/2025
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Sreeparna Pradhan @sreeparnap.bsky.social · 31/12/2025
Moments that brought joy in this otherwise rollercoaster of a year. All spotted in the greater Boston area.
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Jan M. Ache @jan-ache.bsky.social · 19/12/2025
How do animals channel sensory information into motor pathways to generate flexible behavioral output? Excited to share a new preprint addressing this question by leveraging the new #maleCNS connectome, behavioral experiments, and in-vivo recordings: doi.org/10.64898/202.... A long🧵...
Landing and takeoff sensorimotor pathways illustrated alongside fly drawings showing behavioral responses.
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Sreeparna Pradhan @sreeparnap.bsky.social · 26/11/2025
Very cool findings! Looking forward to reading in detail!
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Carlos Ribeiro @ribeirocarlitos.bsky.social · 26/11/2025
Thrilled to share our new paper! With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste. Link @nature.com: www.nature.com/articles/s41...
nature.com
Evolution of taste processing shifts dietary preference - Nature
Calcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in addition to p...
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