Reposted by Shannon McKinney-Freeman
Excellent review in #ExpHem on senescence in HSCs from the @smckinneyfreeman.bsky.social lab at @stjuderesearch.bsky.social. Being able to distinguish cell state at the molecular level is needed to identify these cells and prevent them from contributing to disease.
www.exphem.org/article/S030...
exphem.org
Hematopoietic stem cell senescence and opportunities for intervention
Cellular senescence is a fundamental stress response program involved in embryonic
development, wound healing, immunity, disease pathologies, and aging, which alongside
apoptosis, serves as a protecti...