Reposted by Sofiya Hupalo
Clinical trials in psychiatry rely on measures of symptomatology, not biology. This @acnporg.bsky.social position paper lays out why validated biomarkers in psychiatry have lagged behind fields like Alzheimer's and ALS, and what it will take to close the gap.
www.nature.com/articles/s44...
nature.com
Toward actionable biomarkers in psychiatry: a collaborative roadmap for precision clinical trials. An ACNP position paper - NPP—Digital Psychiatry and Neuroscience
Psychiatric drug development remains constrained by diagnostic heterogeneity, insufficient and inconsistent drug response, high placebo response rates, and the absence of validated biomarkers that can...