Steve Turner @sjturn.bsky.social · 31/08/2026Wordle 1,899 6/6 ⬜⬜⬜⬜⬜ ⬜🟩🟩🟩🟩 ⬜🟩🟩🟩🟩 ⬜🟩🟩🟩🟩 ⬜🟩🟩🟩🟩 🟩🟩🟩🟩🟩 Oh come on! 020
Steve Turner @sjturn.bsky.social · 25/08/2026I love reading @jimmunol.bsky.social (and bluesky, thanks @cyrilpedia.bsky.social) and finding gems like this study..., a reason to publish in learned society journals like #JImmunol #oneofmyfavoritejournals 010
Reposted by Steve TurnerRhys Grinter @rhyswg.bsky.social · 18/08/2026Out now in @natmicrobiol.nature.com: Bacillus subtilis builds protein filaments that act as a pseudomembrane, pulling quinone out of the bilayer and carrying it into the cytosol for reduction by NADH dehydrogenase, well away from the membrane itself. doi.org/10.1038/s415... 1/5 27624
Steve Turner @sjturn.bsky.social · 01/08/2026What is T cell exhaustion? Good question! For some answers, feel free to read our recent review out in @cp-trendsimmuno.bsky.social. Co-authored with @danielutzschneider.bsky.social who made writing this review a great learning experience and a lot of fun. www.sciencedirect.com/science/arti...sciencedirect.com 090
Reposted by Steve TurnerMarion Pepper @marionpepper.bsky.social · 08/07/2026Dr. Marc K. Jenkins is a scientific hero for so many of us. And just a man who loves to sing Johnny Cash for some. Please join us in celebrating his extraordinary career with a retirement symposium at the University of Minnesota on Monday, September 14th! 🎉 To learn more see link in post below👇: 1205
Steve Turner @sjturn.bsky.social · 04/07/2026Great to share our recent review, written with @niclag.bsky.social and @danielthiele1.bsky.social @monashuniversity.bsky.social #monashBDI The evolving biology of T cell memory: A dynamic continuum of function and persistence | Science Immunology www.science.org/eprint/95PIC...science.orgThe evolving biology of T cell memory: A dynamic continuum of function and persistenceAdvances in technology continue to refine our understanding of CD8 T cell memory, with major implications for next-generation vaccines and therapies. 0175
Steve Turner @sjturn.bsky.social · 02/07/2026Wonderful study, if you are into B cells or T cells, or better yet, both, do yourself a favour and give this a read! 030
Reposted by Steve TurnerMax Delbrück Center @mdc-berlin.bsky.social · 23/06/2026From neoantigens to T cell biology: the Afternoon for Immunology returns on June 29. Join researchers from across Berlin for talks and discussion, including a keynote by Paul Klenerman (University of Oxford). Program & registration: 👉 www.mdc-berlin.de/news/events/... 👈 #mdcBerlin #Immunology 043
Reposted by Steve TurnerDaniel Utzschneider @danielutzschneider.bsky.social · 26/05/2026Do you like beach, summer, Greek food AND T cells??? Then please join us for the 1st Aegean conference on T cells in health and disease aegeanconferences.org/conferences/... Registration closes soon (June 15th)!!! 274
Reposted by Steve TurnerGarvan Institute @garvaninstitute.bsky.social · 13/05/2026We welcome the Federal Government's Budget commitment to fully deploy the Medical Research Future Fund – a landmark moment for Australian science. 🔗https://ow.ly/TwFh50YYwyE #MRFF #FederalBudget2026 153
Reposted by Steve TurnerMonika Wolkers @monikawolkers.bsky.social · 11/05/2026👇new study alert! www.biorxiv.org/content/10.6... Wine and cheese gets better and better when it has time to ripen. So did this study. We searched for the rules that regulate the reshaping of the T cell proteome upon activation. Both sequence features in mRNA and RBPs were identified.biorxiv.org 1111
Steve Turner @sjturn.bsky.social · 03/05/2026Great work from @taylahjbennett.bsky.social as part of her PhD studies. GILZ consistently emerges as a top hit in RNA‑seq analyses of T cell responses, including our own, we thought we'd take a look at what it does... Thanks to @jimmunol.bsky.social for highlighting. 060
Reposted by Steve TurnerRhys Allan @rhyscienceallan.bsky.social · 28/04/2026🧬🧬💥💥 I am excited to share a new preprint from our lab “Multi-omic gene regulatory networks informed by 3D chromatin architecture reveal insights into hematopoietic stem cell ageing”. www.biorxiv.org/content/10.6... This is a labour of love by Quinn Stacpoole as part of his PhD.biorxiv.org 142
Reposted by Steve TurnerDr Monique Ryan @mon4kooyong.bsky.social · 21/03/2026‘Medical research isn't just good for our health, it's also great for our economy.’ In this Budget, the govt has to commit to spending money put aside for that purpose in the Medical Research Future Fund. Before we lose more brilliant minds overseas, before we damage the sector irrevocably.theaustralian.com.au 38524
Steve Turner @sjturn.bsky.social · 11/03/2026Hearing from Dr Yue Qu about biofilms and hospital infections. Problem for AMR. Consist of metabolically inactive bacteria (issue for antibiotic uptake), can over come with nano wires that pierce bacterial cells to kill them, similar to dragonfly wings or skin of geckos natureiscool #scienceyeah 020
Reposted by Steve TurnerEpigenome Technologies @epigenometech.bsky.social · 10/03/2026Epigenetics Update - Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains bit.ly/3NmLO5Q Edwina McGlinn and Chen Davidovich (Monash University) reporting in Mol Cell #Epigenetics #PRC2 #H3K27me3 --- Perfect for cancer, immunology, and aging; epigenometech.com 097
Steve Turner @sjturn.bsky.social · 05/03/2026Fantastic work from @davidovichlab.bsky.social Congrats! 010
Reposted by Steve TurnerJeff Mold @jeffmold.bsky.social · 02/03/2026Finally someone did a nice characterization of TSC22D3 (GILZ) in T cell activation I know you T cell omics people have been wondering 042
Steve Turner @sjturn.bsky.social · 02/03/2026Of course, many questions remain but this for the next PhD student, congrats @taylahjbennett.bsky.social, published in @jimmunol.bsky.social 000
Steve Turner @sjturn.bsky.social · 02/03/20266/ This raises therapeutic possibilities: targeting GILZ could enhance effector responses (e.g. in cancer) while preserving immune memory. Conversely, glucocorticoid therapy, which increases GILZ, may dampen T cell activation, helping treat autoimmunity but potentially limiting antiviral immunity. 100
Steve Turner @sjturn.bsky.social · 02/03/20265/ Mechanistically, GILZ restrains the metabolic pathways that fuel T cell activation. Importantly, loss of GILZ boosted effector responses after primary and secondary infection without impairing memory formation.media.tenor.coma woman sitting in a chair with the words marinating in memories written on the bottomALT: a woman sitting in a chair with the words marinating in memories written on the bottom 100
Steve Turner @sjturn.bsky.social · 02/03/20264/ GILZ-deficient CD8 T cells were also more responsive to low-affinity TCR signals. This suggests optimal T cell activation normally requires surpassing a threshold that GILZ helps enforce. In other words, GILZ acts like a molecular handbrake, preventing premature or weak activation. 100
Steve Turner @sjturn.bsky.social · 02/03/20263/ When mice were infected, T cell–specific GILZ deficiency led to stronger antiviral effector CD8⁺ T cell responses. These cells got a boost because they could more readily activate the gene programs required for effective immunity compared to wildtype CD8 T cells.media.tenor.coma man in a car with the words kamino turbo boost written on the screenALT: a man in a car with the words kamino turbo boost written on the screen 100
Steve Turner @sjturn.bsky.social · 02/03/20262/ We found that GILZ is expressed in naïve CD8⁺ T cells, likely maintained by homeostatic glucocorticoid, but is rapidly downregulated once the TCR is engaged. The stronger the signal, the greater the loss of GILZ. So what is it doing in the first place? We tested this using T cells that lack GILZ. 100
Steve Turner @sjturn.bsky.social · 02/03/20261/ Great to highlight our new paper led by @taylahjbennett.bsky.social from her grad work in my lab. We looked how the transcription factor GILZ works as a restraint for T cell activation. A collaboration with Sarah Jones, School Clinical Science @monashuniversity.bsky.social doi.org/10.1093/jimm...doi.orgGlucocorticoid-induced leucine zipper is a primary checkpoint molecule that establishes a virus-specific CD8+ T-cell activation thresholdAbstract. Naïve CD8+ T-cell activation needs to overcome a signaling threshold to initiate the resulting program of T cell proliferation and differentiatio 190
Steve Turner @sjturn.bsky.social · 25/02/2026Standing room only at the @monashuniversity.bsky.social Microbiology seminar today. Hearing from Bob Leung and his work on microbial communities found on the bark of trees and their role in regulating greenhouse gases www.science.org/doi/10.1126/... Amazing science!science.orgBark microbiota modulate climate-active gas fluxes in Australian forestsRecent studies suggest that microbes inhabit tree bark, yet little is known about their identities, functions, and environmental roles. Here we reveal, through gene-centric and genome-resolved metagen... 021
Steve Turner @sjturn.bsky.social · 17/02/2026Last day of #Lornegenome. A great venue, cool talks and discussions. Learnt about diversification of mammalian genomes, inheritance of mutations and impact of mutagens, how TFs direct chromatin organisation and so much more. New collaborations, new projects, can’t wait til next year 0133
Steve Turner @sjturn.bsky.social · 23/01/2026Fantastic new paper from @the-de-lab.bsky.social showing how the CMV m11 protein drives immune evasion by blocking CD44-dependent, FRC-mediated DC migration in the spleen, ultimately dampening antiviral CD8⁺ T cell priming @monashuniversity.bsky.social www.nature.com/articles/s41...nature.comFibroblastic reticular cells direct the initiation of T cell responses via CD44 - NatureCD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune r... 074
Reposted by Steve TurnerDr Shane Huntington OAM @drshanerrr.bsky.social · 22/01/2026Clear skies last night in Melbourne.... 0244
Steve Turner @sjturn.bsky.social · 19/01/2026View from summit of Mt Wellington, Hobart #summerholidays #bitchilly 010
Reposted by Steve TurnerDr Shane Huntington OAM @drshanerrr.bsky.social · 17/01/2026The Orion Nebula. Stunning part of the sky. 0406
Reposted by Steve TurnerDr Monique Ryan @mon4kooyong.bsky.social · 03/01/2026The government can’t claim that medical research is a priority while failing to treat it as one. Nine in 10 leading researchers in Australia are missing out on government support for world‑class proposals, leaving exceptional talent uncertain about their future.theage.com.auMost researchers miss out on innovation grants while medical fund sits on $25bNine in 10 Australian researchers had their “ideas grant” applications rejected last year, even as Australia’s medical investment fund sits on $5 billion more than it was designed to hold. 210748
Steve Turner @sjturn.bsky.social · 17/12/2025Think climate change won’t touch you? Next time a mosquito bites, consider what it might be carrying. As temperatures rise, mosquitoes and other vectors expand their range, bringing viruses like dengue, yellow fever, and malaria (among others) closer to home. Important thread👇 020
Reposted by Steve TurnerColin Carlson @colincarlson.bsky.social · 17/12/2025NSF is about to dismantle NCAR at Russell Vought's direction to protect the fossil fuel industry. It's hard to communicate just how much NCAR does, so let's take a look: I've never worked at NCAR, and I've worked with NCAR researchers once ever. What scientific discoveries has NCAR made possible? 👇 42258352948
Steve Turner @sjturn.bsky.social · 17/12/2025Curiosity sparked it all, and that curiosity just earned one of science’s highest honors. In the Australian, rb.gy/cdwmki Yet government funding for curiosity-driven science is at an all-time low. Success rates are plummeting. If we don’t invest in curiosity, we risk losing the next big discovery. 031
Steve Turner @sjturn.bsky.social · 12/12/2025A year in review at the Biomedical Discovery Institute @monashuniversity.bsky.social a great place to do discovery research that drives transformations in science and health #discoveryresearchmatters #fundresearchproperly 040
Steve Turner @sjturn.bsky.social · 11/12/2025Me at meetings while still waiting on proofs of an accepted manuscript to arrive in my inbox... #comeon #academiclimbo #excitementbuildingmedia.tenor.coma close up of a woman 's face in a dark roomALT: a close up of a woman 's face in a dark room 040
Reposted by Steve TurnerMarc Veldhoen @marcveld.bsky.social · 29/11/2025Five years of COVID taught us one thing: immunology didn’t fail, our public discourse did. My new Substack cuts through the noise with evidence, not ideology. If you want facts over fear, and science over spin, join here: marcveldhoen.substac... 1/2marcveldhoen.substack.comWhat will population immunity to SARS-CoV-2 look like in a post-vaccine world?An updated outlook (2025) 1218641
Steve Turner @sjturn.bsky.social · 10/12/2025Melbourne from the train, weekday evening. #melbournecbd 020
Steve Turner @sjturn.bsky.social · 05/12/2025Finally landed back in Melbourne after 4 hour delay due to faulty plane, Perth #ASI2025 was terrific, great science, great colleagues and great weather! Already looking forward to Canberra #ASI2026 already! 010
Steve Turner @sjturn.bsky.social · 04/12/2025Do yourself a favour and come to hear the fantastic work by @niclag.bsky.social and her team, identifying molecular drivers of age related T cell dysfunction #ASI2025 #Tcellsarecool 030
Steve Turner @sjturn.bsky.social · 04/12/2025Now up in the Thursday Plenary @kerryhilligan.bsky.social the #ASI2025 the Peter Doherty medal recipient, celebrating research excellence by ECRs 021
Steve Turner @sjturn.bsky.social · 03/12/2025Super proud that my PhD mentor being awarded the #Burnetmedal at #ASI2025 in Perth, Frank Carbone and the discovery of cross-presentation, and its role in priming killer T cell responses, using his original lecture slides from late 80’s #classicfrank 0111