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Monika Wolkers

@monikawolkers.bsky.social
593 followers 701 following 81 posts

T cell Immunologist, with a passion for RNA biology and translation control and the role of RBPs herein. Working at Sanquin Blood Supply, Amsterdam. Oncode Institute investigator

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Reposted by Monika Wolkers
Danny IncaRNAto @incarnatolab.bsky.social · 09/10/2026
#RNA Framework 2.9.8 is out! Check the full CHANGELOG: github.com/dincarnato/R.... Get the latest version at: github.com/dincarnato/R... This release features a major renovation of the engine. A few highlights in a short thread (1/n).
github.com
RNAFramework/CHANGELOG.md at master · dincarnato/RNAFramework
RNA structure probing and post-transcriptional modifications mapping high-throughput data analysis - dincarnato/RNAFramework
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Monika Wolkers @monikawolkers.bsky.social · 01/10/2026
very cool work from the Crotty lab on durability of airway CD4?CD8 T cell responses in humans! www.biorxiv.org/content/10.6...
biorxiv.org
Durability and diversity of human upper airway T cell memory
T cells are major contributors to protective immunity against pathogens and cancers. Immune memory is a central feature of protective adaptive immunity, and mucosal barrier tissues are major sites of ...
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Monika Wolkers @monikawolkers.bsky.social · 01/10/2026
fantastic work, it is a must-read!
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Gonçalo C. Vale @goncalocvale.eurosky.social · 21/09/2026
WTF?
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Mohamed ElTanbouly @plasmacellguy.bsky.social · 16/09/2026
Hello! I've started my lab and we're looking to hire at multiple positions: 1-Postdoc 2-Scientist (primarily Computational biologists) 2-Lab manager 3-Tech If you're interested, please reach out to my institutional email. Looking forward to discussing further.
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Monika Wolkers @monikawolkers.bsky.social · 10/09/2026
Now out in print. We studied the interactome of ZFP36L1 in human T cells We show how its interactome changes throughout T cell activation And whether or not interactions require the presence of RNA Great collaboration with @julienbethune.bsky.social www.life-science-alliance.org/content/9/11...
life-science-alliance.org
Proximity labeling puts ZFP36L1 as central hub for posttranscriptional regulation networks in T cells
Effective T cell responses against pathogens require a rapid yet tightly controlled remodeling of the proteome, and RNA binding proteins (RBPs) are key in this process. For instance, the RBP ZFP36L1 p...
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Monika Wolkers @monikawolkers.bsky.social · 30/08/2026
👇Super excited about this work. 👇 Our first proteome analysis of tumor-reactive T cells from non-small cell lung cancer lesions. We identify differentially expressed proteins that we would have missed with RNA-seq. We learned how CHD4 and FASN contribute to T cell differentiation and function.
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Queen Mary University of London @qmul.bsky.social · 19/08/2026
Air pollution stunts children’s lung growth. New Queen Mary research found that improvements in air quality after the introduction of London’s ULEZ are associated with accelerated lung growth in children. Read more: shorturl.at/Jx86o
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Monika Wolkers @monikawolkers.bsky.social · 05/08/2026
This is fantastic news! Vaccination yields substantial drop in hospital admission for malaria
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zunigalab.bsky.social @zunigalab.bsky.social · 04/08/2026
Hi there #DC2026—late-breaking abstracts just OPEN TODAY! Join us at the international #dendriticcell community premier conference in beautiful #SanDiego for cutting-edge #immunology, collaboration, and networking! 📍 Oct 11–14, 2026. Register today! dc2026sandiego.com
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Maria Hondele @mariahondele.bsky.social · 03/08/2026
🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan ! How are mRNPs remodeled as they exit the nucleus? We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
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Monika Wolkers @monikawolkers.bsky.social · 29/07/2026
ist ganz sicher unterstützungswürdig! innn.it/boellerverbot
innn.it
Petition · Bundesweites Böllerverbot, jetzt! · innn.it
Jetzt innn.it-Petition unterschreiben & Gewerkschaft der Polizei Berlin unterstützen!
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Holger Hestermeyer @hhesterm.bsky.social · 05/07/2026
AI firms are now destroying our cultural heritage: they are buying massive amounts of used books, scanning them in likely violation of copyright laws, training their models and destroying the books. www.tagesschau.de/kultur/ki-fi...
tagesschau.de
KI-Firmen kaufen offenbar Antiquariate leer - Buchhändler alarmiert
Es sind sonderbare Bestellungen: Massenweise werden in Antiquariaten innerhalb kürzester Zeit online Ladenhüter bestellt. Dahinter stecken vermutlich Firmen, die ihre KI trainieren. Nicht nur Buchhänd...
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Lauren Dobson-Hughes @ldobsonhughes.bsky.social · 24/06/2026
Musk says not a single person has died due to him axing USAID. Sadly, part of my job involves tracking aid spending. So here’s a thread with just some of the people who lost their lives because of USAID cuts
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Prof Christina Pagel @chrischirp.bsky.social · 22/05/2026
Important explanation that these headlines were not based on any science but are essentially the opinions of well connected people. open.substack.com/pub/gidmk/p/...
open.substack.com
Ill Health In Old Age Is Not 80% "Down To The Individual"
This is why we rely on evidence rather than opinions.
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Monika Wolkers @monikawolkers.bsky.social · 21/05/2026
oh boy...
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 08/05/2026
Decoding translational control by cis-regulatory elements and RNA binding proteins in human effector T cells www.biorxiv.org/content/10.64898/20…
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Monika Wolkers @monikawolkers.bsky.social · 11/05/2026
👇new study alert! www.biorxiv.org/content/10.6... Wine and cheese gets better and better when it has time to ripen. So did this study. We searched for the rules that regulate the reshaping of the T cell proteome upon activation. Both sequence features in mRNA and RBPs were identified.
biorxiv.org
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Scott Horton @robertscotthorton.bsky.social · 03/04/2026
Every voter needs to see this before the midterms. And we should flag that Trump makes these remarks during an event orchestrated by his Office of Faith Initiatives to mark Holy Week. bsky.app/profile/atru...
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B4Ukraine @b4ukraine.org · 30/03/2026
A signature collection has opened on the European Commission’s website for an EU citizens’ initiative to completely ban imports from Russia & Belarus. The petition must collect 1M signatures by Feb 2027 to be considered by the Commission. Show you care. Say no to trade with Russia: bit.ly/4v1ai5C
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Brent Toderian @brenttoderian.bsky.social · 01/04/2026
“When mayors in other cities ask me how #Copenhagen afforded to invest in its cycling networks, I ask them how on earth they have been able to afford highway projects. We invested in bike lanes because that was the cheapest option.” What the world can learn from Copenhagen’s cycling revolution.
theprogressplaybook.com
Copenhagen Cycling Revolution: Lessons for Cities
Close to two-thirds of the city’s residents commute by bike to school or work every day.
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Monika Wolkers @monikawolkers.bsky.social · 25/03/2026
www.theguardian.com/world/2026/m...
theguardian.com
No Israel prosecutions for killing Palestinian civilians in occupied West Bank since start of decade
Dozens of former Israeli military, police and spy chiefs describe situation as ‘organised Jewish terrorism’
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xavier salvatella @xsalvatella1.bsky.social · 16/03/2026
Happy to announce that my institution, @irbbarcelona.org, is opening two group leader positions, 1 in chemical biology and 1 in structural biology, to strengthen our expertise in molecular sciences: please spread the word !
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Monika Wolkers @monikawolkers.bsky.social · 23/03/2026
what a wonderful reflection on mRNA vaccines- science versus misinformation. Absolutely worth a read!!! rnajournal.cshlp.org/content/earl...
rnajournal.cshlp.org
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Monika Wolkers @monikawolkers.bsky.social · 12/03/2026
WOW... I am speechless.
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γδ T cell Forum @forum-gd.bsky.social · 17/02/2026
Join us for our March #GDTcellclub webinar talks with Drs. Judith Wienke (Utrecht) and Monika Wolkers (Sanguine BSF) on March 19 at 12pm NY time. Zoom ID: 958 9051 7066/ passcode 369081 nyulangone.zoom.us/j/9589051706...
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Monika Wolkers @monikawolkers.bsky.social · 04/02/2026
(1) Did you ever wonder how effector T cells remodel their transcriptome and proteome when they become activated? and how this remodelling drives T cell diffferentiation? Then you might be interested in our newest preprint:👇 www.biorxiv.org/content/10.6...
biorxiv.org
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Seth Thomas Scanlon @immunoeditor.bsky.social · 27/01/2026
@science.org is looking for a new research editor to handle papers in the field of next-generation #medicine! Spread the word!!! bit.ly/4bWOJfn
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Monika Wolkers @monikawolkers.bsky.social · 10/12/2025
👇 our newest preprint. A tour de force by Valeria to bring OOPS into primary T cells. With new MS analysis pipeline PROMOGEB from Koos allowing for multivariate comparisons. AND interesting biological outcomes. Enjoy! #Tcells #RNA #Immunology #RBP @oncodeinstitute.bsky.social @erc.europa.eu, LSBR
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Monika Wolkers @monikawolkers.bsky.social · 05/12/2025
👇See our newest study: What was supposed to be a control experiment uncovered a new function of mTOR: 3’mediated translation control in primary human T cells, mediated through DDX21. AU-rich elements are required for this effect. Happy reading! authors.elsevier.com/a/1mDFf3vVUP...
authors.elsevier.com
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Nikolai Slavov @slavov-n.bsky.social · 26/10/2025
Very concerning. New research coordinated by the European Broadcasting Union (EBU) and led by the BBC has found that AI assistants – already a daily information gateway for millions of people – routinely misrepresent news content no matter which language, territory, or AI platform is tested.
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The EMBO Journal @embojournal.org · 17/10/2025
T-cell smFISH: @anilevetu.bsky.social, @monikawolkers.bsky.social et al present an optimized workflow for simultaneously quantifying nascent and mature mRNA, and its localization with single-cell resolution in human T-cells #RefereedPreprint c/o @reviewcommons.org www.embopress.org/doi/full/10....
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Monika Wolkers @monikawolkers.bsky.social · 14/10/2025
I am super proud that this paper is now out in EMBO Journal lnkd.in/ev843k7P What did we do? we optimized imaging of single molecules, in our case cytokine mRNAs with smFISH in primary human T cells.
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Matthias Eberl @eberlmat.bsky.social · 02/10/2025
Somehow we don't talk about this enough.
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Monika Wolkers @monikawolkers.bsky.social · 03/09/2025
our study on #gdTcells in pediatric neuroblastoma is out! In contrast to adult tumors, it is the gdTcells that not only expand, but that are the most tumor reactive #TILs. #immunology #tumorimmunology funded by KIKA, Sanquin and supported by Oncode www.life-science-alliance.org/content/8/11...
life-science-alliance.org
γδ T cells are the prime antitumoral T cells in pediatric neuroblastoma
High-risk pediatric neuroblastoma patients have a dismal survival rate despite intensive treatment regimens. New treatment options are thus required. Even though HLA expression in neuroblastoma is low...
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Monika Wolkers @monikawolkers.bsky.social · 03/09/2025
our study on #gdTcells in pediatric neuroblastoma is now out in
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DonnaDee 💙 @overallthiscrap.bsky.social · 30/08/2025
Unvaccinated citizens in the 50s
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Olga Nesterova @onestpress.onestnetwork.com · 18/08/2025
Kharkiv right now. Moscovia bombs sleeping families. 4 victims including kids. Don’t tell me about peace that Putin wants. Do not dare.
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Ben Nicolet @bnicolet.bsky.social · 01/08/2025
Can you boost the protein expression in specific cell types? That is what we asked in our study published a week ago in @scienceadvances We used machine learning (AI) to learn the code for protein expression in immune cells. www.science.org/doi/10.1126/...
science.org
Learning the sequence code of protein expression in human immune cells
SONAR informs the design of cell type–specific protein expression in human cells.
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Monika Wolkers @monikawolkers.bsky.social · 29/07/2025
👇New preprint: Proximity labeling in human T cells uncovers ZFP36L1 as central hub for post-transcriptional gene regulation. We found known and unknown ZFP36L1 interactors, their interaction dynamics and RNA (in)dependency, elucidating ZFP36L1's multifaceted role. www.biorxiv.org/content/10.1...
biorxiv.org
Proximity labeling reveals ZFP36L1 as a central hub for post-transcriptional regulation networks in T cells
Effective T cell responses against pathogens require a rapid yet tightly controlled remodeling of the proteome, and RNA binding proteins (RBPs) are key in this process. For instance, the RBP ZFP36L1 p...
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Monika Wolkers @monikawolkers.bsky.social · 23/07/2025
it is finally out! 👇 our #ML pipeline SONAR, which can predict the protein abundance in #immune cells. Using sequence features present in the #RNA. With @bnicolet.bsky.social Supported by the @erc.europa.eu and@oncodeinstitute.bsky.social www.science.org/doi/epdf/10....
science.org
Learning the sequence code of protein expression in human immune cells
You have to enable JavaScript in your browser's settings in order to use the eReader.
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Monika Wolkers @monikawolkers.bsky.social · 17/07/2025
super proud of Kaspar for receiving the VENI grant from NWO-ZonMW. And I am very excited to see what he will find! www.linkedin.com/posts/sanqui...
linkedin.com
🎉 Kaspar Bresser, who works at Sanquin in Monika Wolkers' group and at Amsterdam UMC, has been awarded a Veni grant from the NWO (Dutch Research Council) for his research into how T cells develop…...
🎉 Kaspar Bresser, who works at Sanquin in Monika Wolkers' group and at Amsterdam UMC, has been awarded a Veni grant from the NWO (Dutch Research Council) for his research into how T cells develop ...
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Insta Science @instascience.bsky.social · 06/07/2025
When birds saw humans give an injured bird special treatment.😅
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Monika Wolkers @monikawolkers.bsky.social · 07/07/2025
Bekijk Stop de asielwetten op groenlinkspvda.nl/petitie/stop...
groenlinkspvda.nl
Teken de petitie: Stop de asielwetten | GroenLinks-PvdA
Stop de asielwetten! Deze wetten van het kabinet Wilders-Yesilgöz zijn asociaal, onverantwoord en onmenselijk. Teken de petitie en hou ze tegen.
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Payal Yokota @payalyokota.bsky.social · 23/05/2025
The unparalleled @bsilvasantos.bsky.social concludes the amazing #gammadeltatoronto with the keynote talk. A moment I've waited for since may2022 inaugural #gdtcellclub talk. Super excited to see the wrap up for the unbelievable conf thanks to JC and the other fellow organizers. Let's go!!
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Joachim Goedhart @joachimgoedhart.bsky.social · 12/05/2025
Job opportunity at our institute at the University of Amsterdam: www.academictransfer.com/en/jobs/3519...
academictransfer.com
Assistant Professor Computational Analysis of Single-cell and Spatial Omics Data
Are you passionate about developing omics data analysis methodology? Are you fascinated by the opportunities of omics data at single-cell or spatial resolution? Would you like to work at the forefront...
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Monika Wolkers @monikawolkers.bsky.social · 03/05/2025
👇super nice work on TCR-pMHC prediction by the Schumacher lab. Congrats!
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Monika Wolkers @monikawolkers.bsky.social · 29/04/2025
happy #dayofimmunology! It also happens to be my birthday and guess what my profession is - could not be better fitting, no?!
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The American Association of Immunologists @aai.org · 02/04/2025
The myth that the childhood vaccine against measles, mumps, and rubella (MMR) causes autism is based on a discredited study falsely linking the vaccine to autism. Find out more: ow.ly/EqeC50VlKva. #ImmunologyExplained #Measles #MedSky #MMR
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George Takei @georgetakei.bsky.social · 30/03/2025
And yet Joe Rogan puts guests on who say "Vaccines aren't actually responsible for the reduction in infectious diseases.”
The image is a heatmap titled "Measles," showing measles cases across U.S. states from 1928 to 2003. States listed on the y-axis include Alaska, Arkansas, California, Connecticut, Delaware, Georgia, Iowa, Illinois, Kansas, Louisiana, Maryland, Michigan, Missouri, Montana, North Dakota, New Hampshire, New York, Oklahoma, Pennsylvania, South Carolina, Tennessee, Utah, Vermont, Wisconsin, and Wyoming. The x-axis spans years from 1928 to 2003. A vertical line marks the introduction of the measles vaccine around 1963. The color scale at the bottom ranges from blue (0 cases) to red (4,000+ cases), with shades of green, yellow, and orange indicating intermediate values (1,000, 2,000, 3,000 cases). Before 1963, many states show frequent high case numbers (yellow to red), while after 1963, cases drop significantly, with mostly blue indicating near-zero cases.
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