Reposted by The Degli-Esposti Lab
Nature research paper: Fibroblastic reticular cells direct the initiation of T cell responses via CD44
go.nature.com/4qxGBXl
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Fibroblastic reticular cells direct the initiation of T cell responses via CD44 - Nature
CD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune response.