iiinova — where your digital self keeps evolving

Sergei Koralov @sbkoralov.bsky.social · 26/05/2026

Happy to share our News & Views in @nature.com on the beautiful work by Nicola et al., showing that B cells in autoimmune thyroid disease acquire mutations in checkpoint genes. Supporting the classic hypothesis of "forbidden" clones as drivers of #autoimmunity by Burnet, Goodnow… rdcu.be/fkRrI

rdcu.be

022

Sergei Koralov @sbkoralov.bsky.social · 04/03/2026

Great @nytimes.com article. “Thirteen months into the second Trump administration, science, medicine and public health have been hijacked by a cadre of grifters and ideologues and by the politicians in obvious thrall to both.” When Science Became the Enemy www.nytimes.com/2026/02/23/o...

000

Sergei Koralov @sbkoralov.bsky.social · 04/02/2026

Congrats on this beautiful work, Chrys!

100

Sergei Koralov @sbkoralov.bsky.social · 17/12/2025

#Citibike PLEASE make an effort to free up docks at Penn Station at peak hours (5-8pm). Whenever it is cold or near holidays, the situations is terrible - no available bike parking at any stations near Penn! You also made it near impossible to provide feedback on your app!

000

Reposted by Sergei Koralov

E John Wherry @ejohnwherry.bsky.social · 08/09/2025

What a huge loss. I am so sorry to hear this news. David was a tremendous positive presence across all biomedical science. A once in a generation kind of scientist. www.nytimes.com/2025/09/07/s...

nytimes.com

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

0103

Reposted by Sergei Koralov

Igor Brodsky @brodskyigorlab.bsky.social · 08/09/2025

www.latimes.com/obituaries/s... RIP David Baltimore. A true giant of biomedical research. Made so many fundamental discoveries: Reverse transcriptase; NF-kB; Rag genes (among others) Also shut down his lab for a week in 1970 to protest the US invasion of Cambodia.

latimes.com

David Baltimore, Nobel Prize-winning scientist and former Caltech president, dies at 87

Baltimore played a role in virtually every important national debate over the use and potential misuse of the science of genetic engineering.

02910

Reposted by Sergei Koralov

Jim Woodgett @jwoodgett.bsky.social · 24/07/2025

Good grief, the US National Cancer Institute projects it will fund only one in 25 RO1 grant applications in 2026. This is massively defunding cancer research. Despicable vandalism. www.cancer.gov/grants-train...

National Cancer Institute projection of a 4% pay line in FY2026.

5302152

Reposted by Sergei Koralov

PoliticsGirl @politicsgirl.bsky.social · 11/07/2025

Try and make it through this. Really watch. youtube.com/shorts/tEVFP...

youtube.com

Do Not Look Away

YouTube video by PoliticsGirl

921340751

Reposted by Sergei Koralov

Terkild Brink Buus @terkild.bsky.social · 19/06/2025

❗How can a cancer exploit its environment and still resist treatment? ✅The answer: co-existing malignant subclones. Let me walk you through our latest study investigating how divergent evolution drives adaptability, aggressiveness, and drug resistance of T cell cancer. 1/🧵 doi.org/10.1158/2159...

Schematic figure showing divergent evolution of malignant subclones and how they migrate to different tissue compartments (blood vs skin), respond differently to extrinsic stimuli such as Staphylococcus aureus enterotoxins, and how subclones differ in their intrinsic resistance to anti-cancer drugs.

2249

Reposted by Sergei Koralov

Stand Up for Science! @standupforscience.net · 30/05/2025

McCarthyism 2.0: Now with added racism. Trump wants to purge Chinese students from U.S. universities under the guise of “national security.” This isn’t defense — it’s discrimination, plain and simple. We stand up for international students. www.politico.com/news/2025/05...

politico.com

Behind Trump’s long campaign to target Chinese student visas

The president's action comes amid a fragile trade truce on the line.

414941

Reposted by Sergei Koralov

Pete Buttigieg @petebuttigieg.bsky.social · 23/05/2025

America cannot long remain free, nor first among nations, if it becomes the kind of place where universities are dismantled because they don't align politically with the current head of the government.

14424769011267

Sergei Koralov @sbkoralov.bsky.social · 16/05/2025

The BOSS: “"In my home, the America I love, the America I've written about, that has been a beacon of hope and liberty for 250 years, is currently in the hands of a corrupt, incompetent and treasonous administration." youtu.be/n-kODkdNSgs

youtu.be

Bruce Springsteen’s Message to America: A Protest. A Prayer. A Wake-Up Call.

YouTube video by The Seneca Project

010

Sergei Koralov @sbkoralov.bsky.social · 15/05/2025

My understanding is she was carrying frog embryos for cancer biology work in her mentor’s lab at Harvard - this is not some espionage ffs! Given the political views that many Russian expats hold, deporting her back to Russia is inhumane to say the least! www.nytimes.com/2025/05/14/h...

nytimes.com

U.S. Charges Russian Scientist With Smuggling

120

Reposted by Sergei Koralov

Igor Brodsky @brodskyigorlab.bsky.social · 14/05/2025

Another example of the current administration’s war on science. Instead of allowing a talented and highly trained scientist to do her job and make discoveries that will benefit human health they are trying to deport her. Shame. 😳😱

173

Reposted by Sergei Koralov

George Takei @georgetakei.bsky.social · 02/05/2025

The rise in autism diagnosis rates is real. The panic over an “autism epidemic”? Manufactured by the likes of RFK Jr., who has led the ignorant down a dangerous path of disinformation.

thinkbigpicture.substack.com

The Autism Epidemic That Never Was

RFK Jr.'s scientific illiteracy has led the ignorant down a dangerous path.

2293882822

Reposted by Sergei Koralov

Andrea L Graham @grahammunology.bsky.social · 02/05/2025

Devastating indeed for the future of basic research 🤬 but also portends further tanking of the current economy!!! 😵‍💫 by this clueless culture warring (?) administration that needs to receive a lot of FEEDBACK no make that BLOWBACK please people 💪🚫

001

Reposted by Sergei Koralov

The American Association of Immunologists @aai.org · 02/05/2025

Recent federal actions have done great harm to scientists all across the country. Tell Congress your story & urge strong NIH support for FY26 ($51.3B+)! #InvestInScience ✍️ ow.ly/Xet850VJHkU #AAIadvocacy

022

Sergei Koralov @sbkoralov.bsky.social · 02/05/2025

This keeps getting worse. I am yet to hear a single republican express any real concern about the impact the cuts to NIH and the abrupt stop in funding by NSF will have on US science and healthcare, let alone see any evidence of “bipartisan” action.

184

Reposted by Sergei Koralov

Ossoff's Office @ossoff.senate.gov · 30/04/2025

Sen. Ossoff: Who out there in the American public is sitting at home demanding that we shut down cancer research and Alzheimer's research?

623288478546

Sergei Koralov @sbkoralov.bsky.social · 30/04/2025

www.youtube.com/watch?v=8H34... I have to admit, John Oliver outlining exactly what is wrong with HHS cuts and with RFK in great detail, was not what I would have expected. But this is sadly very accurate.

youtube.com

RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)

YouTube video by LastWeekTonight

031

Reposted by Sergei Koralov

Middle Age Riot @middleageriot.bsky.social · 23/04/2025

In their defense, the authors of the Constitution could never have predicted that American voters would be this stupid.

47882167

Reposted by Sergei Koralov

Barack Obama @barackobama.bsky.social · 15/04/2025

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

15568915518162

Reposted by Sergei Koralov

Shruti Naik @drshrutinaik.bsky.social · 16/04/2025

APRIL 30th Senate session to discuss NIH funding cuts and biomedical research in America. Mark your calendars and call your senetors!!! www.appropriations.senate.gov/hearings/bio...

appropriations.senate.gov

Biomedical Research: Keeping America’s Edge in Innovation | United States Senate Committee on Appropriations

United States Senate Committee on Appropriations

01014

Reposted by Sergei Koralov

Aaron Rupar @atrupar.com · 05/04/2025

Mark Kelly: "This is not surprising. Here's a guy who told Americans to inject bleach into their bodies, who sent a mob to Capitol Hill. And now I think it's fair to say he stands out as singlehandedly destroying more wealth with his bad decisions than anybody else who has ever lived on this planet"

10555453113823

Reposted by Sergei Koralov

Igor Brodsky @brodskyigorlab.bsky.social · 29/03/2025

This is an understatement. We have already lost our scientific edge. Mass personnel cuts, lost grant support, gutting of pipeline programs, and the uncertainty about the future has already impacted our competitiveness and future generations of scientists. We just don’t see it yet. But we will.

20725184

Sergei Koralov @sbkoralov.bsky.social · 29/03/2025

www.nytimes.com/live/2025/03... The few remaining officials with a conscience and critical thinking skills are being forced out.

nytimes.com

Trump Administration Live Updates: Top Vaccine Official at F.D.A. Resigns, and Criticizes Kennedy

010

Reposted by Sergei Koralov

Mrs. Betty Bowers @mrsbettybowers.bsky.social · 27/03/2025

I learned this week that you can put our troops' lives in danger, compromise our national security, and violate the Espionage Act. And the government will do nothing. But if you write an editorial for your school newspaper that Trump doesn't like, you will be abducted on the street and disappeared.

21088583428

Reposted by Sergei Koralov

David Woodruff @dmwoodruff.bsky.social · 27/03/2025

A very old Soviet joke, from an especially dark time: Foxes are fleeing the USSR in droves. Q: Why are you running away? Fox: The Soviets passed a new law that they’re going to arrest all camels. Q: But you’re foxes! Fox: Yeah, why don’t *you* try proving to the NKVD that you’re not a camel.

110136364874

Reposted by Sergei Koralov

Igor Brodsky @brodskyigorlab.bsky.social · 19/03/2025

Not a good sign. Very concerned for the future of American science rn.

051

Sergei Koralov @sbkoralov.bsky.social · 19/03/2025

Trump silencing Voice of America has far-reaching consequences. In autocratic regimes, it's often the only real news source—just as it was in the USSR, where people risked much to tune in. VOA’s broadcasts in many languages provide vital info. This move hands a win to dictators everywhere.

111

Reposted by Sergei Koralov

Cadwell Lab @cadwelllab.bsky.social · 08/03/2025

Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/... Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n

science.org

Rewilding catalyzes maturation of the humoral immune system

Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

47720

Sergei Koralov @sbkoralov.bsky.social · 07/03/2025

@labwaggoner.bsky.social thank you for the spotlight! This has been a wonderful joint effort led by @cadwelllab.bsky.social in close collaboration @grahammunology.bsky.social, @belkaidlab.bsky.social, and P’ng Loke’s groups. First authors Ying-Han and Kim Zapdana led the way.

031