iiinova — where your digital self keeps evolving

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Cornelius Gati @gati.bsky.social · 28/09/2025

A very special thanks to Dr. Vera Moiseenkova-Bell and Dr. John Wherry @ejohnwherry.bsky.social for their extraordinary support in making this happen.

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E John Wherry @ejohnwherry.bsky.social · 08/09/2025

What a huge loss. I am so sorry to hear this news. David was a tremendous positive presence across all biomedical science. A once in a generation kind of scientist. www.nytimes.com/2025/09/07/s...

nytimes.com

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

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E John Wherry @ejohnwherry.bsky.social · 06/09/2025

Yesterday we opened a new home for Immunology at Penn. Part of our large vibrant immunology community will move into this amazing space. This includes our #ColtonCenter for Autoimmunity, #ImmuneHealth and more. youtu.be/Ryv2AxPtb_E?...

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YouTube

Share your videos with friends, family, and the world

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E John Wherry @ejohnwherry.bsky.social · 14/08/2025

What's the difference between Trm and exhausted CD8 T cells? Simone Park's new work dissects this important question. These cell types are often confused, but are ontologically and mechanistically distinct with implications for immunotherapy responses. www.biorxiv.org/content/10.1...

biorxiv.org

Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8+ T cells underlies distinct functional potential

Persistent antigen stimulation promotes differentiation of exhausted CD8+ T (TEX) cells. TEX cells are distinct from circulating memory T (TCIRCM) cells but share many features with tissue-resident me...

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E John Wherry @ejohnwherry.bsky.social · 14/08/2025

A great Keystone meeting on Long COVID this week in Santa Fe. The field has made great progress recently, but there is much more to do. Exciting science presented about viral and immune mechanisms, clinical data and future clinical trials. www.keystonesymposia.org/conferences/...

keystonesymposia.org

Long COVID and Other Post-Acute Infection Syndromes | Keystone Symposia

Join us at the Keystone Symposia on Long COVID and Other Post-Acute Infection Syndromes, August 2025, in Santa Fe, with field leaders!

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The Atlantic @theatlantic.com · 24/07/2025

Ozzy Osbourne was an agent of darkness and a beloved family man alike. “This cognitive dissonance is precisely why he was regarded as a titan,” Spencer Kornhaber writes: theatln.tc/7b1rHz12

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David J. Skorton @davidjskorton.bsky.social · 16/06/2025

I’ve been in academic medicine for 45 years. This is the first time I’m seeing a perfect storm, as proposed federal funding cuts threaten our ability to provide patient care, train the next generation of doctors, and conduct life-saving research. More from my conversation with @cnn.com last week.

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E John Wherry @ejohnwherry.bsky.social · 27/05/2025

A useful distraction this weekend....

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Hensley Lab @scottehensley.bsky.social · 16/05/2025

To be clear, these kinds of breakthroughs are going to come to a screeching halt with the current NIH funding cuts. This new treatment is only possible because of decades of basic research. What might be possible 20 years from now if we don't destroy basic research? www.nature.com/articles/d41...

nature.com

World’s first personalized CRISPR therapy given to baby with genetic disease

Treatment seems to have been effective, but it is not clear whether such bespoke therapies can be widely applied.

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The New York Times @nytimes.com · 16/05/2025

Breaking News: Moody’s has downgraded the credit rating of the U.S., becoming the third major credit rating agency to downgrade the country since 2011.

nytimes.com

Trump Administration Live Updates: Supreme Court Extends Freeze on Use of Alien Enemies Act for Deportations

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Gregg Gonsalves @gregggonsalves.bsky.social · 16/05/2025

Word. “The future of biomedical research in the United States comes down to a race to see whether the biomedical research community can mobilize politically, access that vast but latent political power, before the White House can do enough sustained damage to make the whole question moot.”

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Apoorva Mandavilli @apoorvanyt.bsky.social · 15/05/2025

RFK Jr. said multiple times during his house and senate hearings today that no scientists have been fired from federal agencies. Our reporting has shown that hundreds, if not thousands, of scientists have been let go from NIH/CDC/FDA

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E John Wherry @ejohnwherry.bsky.social · 12/05/2025

So this is not a problem?...But we can't even buy an NIH researcher a cup of coffee because of conflicts of interest!? The hypocrisy is insane. Investigations into universities, but at the White House all gifts and straight up crypto-bribes are fine. WTF www.nytimes.com/2025/05/11/u...

nytimes.com

Trump Is Poised to Accept a Luxury 747 From Qatar for Use as Air Force One

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Parker Institute for Cancer Immunotherapy (PICI) @parkerici.bsky.social · 06/05/2025

Congrats to @ejohnwherry.bsky.social, PhD—pioneer of T cell exhaustion and checkpoint biology—on his election to the National Academy of Sciences. A well-earned honor for work that continues to drive immunotherapy forward. www.nasonline.org/news/2025-na... #NAS2025

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E John Wherry @ejohnwherry.bsky.social · 04/05/2025

Use this link to write to your representatives as often as possible!! secure.everyaction.com/1ExSmGrI2kqH...

secure.everyaction.com

How Uncertainty About Federal Support for Science Impacts You and Your Institution

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Saganism @sagan.bsky.social · 02/05/2025

Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".

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Institute for Immunology and Immune Health (I3H) @i3h-upenn.bsky.social · 02/05/2025

Congratulations to @ejohnwherry.bsky.social and Penn colleagues, Katalin Karikó, Virginia Lee (@pennpathlabmed.bsky.social) and Mark Devlin on being elected as members of the @nasonline.org—one of the highest honors a scientist can receive!

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Joe Zackular @joeyzacks.bsky.social · 29/04/2025

Congratulations to all of the new National Academy of Sciences members!! Special shout out to @ejohnwherry.bsky.social and Eric Skaar!!! So well deserved!

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Jeremy Berg @jeremymberg.bsky.social · 27/04/2025

TV watching recommendations The lead story on 60 Minutes tonight is about NIH and concerns about damage done and continuing during the current administration. 1/2

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American Association for Cancer Research (AACR) @theaacr.bsky.social · 27/04/2025

This afternoon at #AACR25: Attend an important panel discussion about the impact of recent federal actions on cancer research. Learn more in AACR Annual Meeting News: www.aacrmeetingnews.org/news/policy-... @ejohnwherry.bsky.social

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George Takei @georgetakei.bsky.social · 24/04/2025

When the moment came, Harvard didn’t hedge or flinch—it stood up. A reminder that integrity isn’t complicated, it’s just rare.

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Hensley Lab @scottehensley.bsky.social · 16/04/2025

After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors. www.nature.com/articles/s41...

nature.com

Bovine H5N1 binds poorly to human-type sialic acid receptors - Nature

Nature - Bovine H5N1 binds poorly to human-type sialic acid receptors

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Jane Yinghui Huang @janehuang.bsky.social · 28/03/2025

Excited to share my graduate work from the @ejohnwherry.bsky.social lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @science.org immunology. Main findings below! www.science.org/doi/10.1126/...

science.org

Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate

TOX safeguards exhaustion biology in established Tex cells and restrains fate conversion to Teff cells.

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Barack Obama @barackobama.bsky.social · 25/03/2025

Right now, there’s an important race happening that will shape the Wisconsin Supreme Court for the next 10 years. Judge Susan Crawford is ready to protect the fundamental rights and freedoms of all Wisconsinites. Make a plan to vote early today — don’t wait until April 1st: wisdems.org/vote

wisdems.org

Find Your Voting Locations | WISDEMS Voter Protection Team

This searchable map shows you early voting and dropbox info for hundreds of villages, towns, and cities across Wisconsin. Enter the address you're registered at and your options will pop up!

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Mark Cuban @mcuban.bsky.social · 22/03/2025

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

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Angie Rasmussen @angierasmussen.bsky.social · 22/03/2025

So the anti-vax organization founded by the current HHS secretary is hosting a dark mirror bullshit clone of the CDC’s website. No wonder they were in such a hurry to delete the CDC’s data.

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E John Wherry @ejohnwherry.bsky.social · 13/03/2025

Uber should offer a “no tesla” option

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The American Association of Immunologists @aai.org · 07/03/2025

Long COVID is an often debilitating condition estimated to affect nearly 17 million Americans. AAI members, @virusesimmunity.bsky.social and @ejohnwherry.bsky.social provided expert insight on the future of treatments and research at AAI's first-ever congressional briefing. ow.ly/YXZj50Vb3sq.

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