On-the-fly conditioning of pretrained protein generative models guides protein generation toward specific properties.

Adenine base editors (ABEs) are CRISPR effectors that introduce A-T to G-C transitions in the genome using a nucleotide deaminase fused to a Cas protein. ABEs have been evolved to have very high editi...

TnpB endonucleases are engineered for improved genome editing.

PhD Project - Engineering plant rubisco enzymes through high-throughput enzyme assays and cryo-EM (Plant BioDesign Cambridge project) at University of York, listed on FindAPhD.com

Antiviral immune systems diversify by integrating new genes into existing pathways, creating new mechanisms of viral resistance. We identified genes encoding a predicted nuclease paired with a trypsin...