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Rod Rahimi

@rodrahimi.bsky.social
4.1K followers 1.6K following 607 posts

Physician-Scientist at Massachusetts General Hospital. Posting about biology (mostly immunology) and medicine www.rahimi-lab.com

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Rod Rahimi @rodrahimi.bsky.social · 09/10/2026
“‘I imagine many mathematicians, like me, felt like they got punched in the stomach yesterday,’ Dr. Ono said. ‘But that feeling is quickly giving way to excitement and determination. For those working to push mathematics forward, this is a challenge and an invitation to aim higher.’”🧪
nytimes.com
‘Breathtaking,’ ‘Devastating’: Mathematics Reels After New OpenAI Release (Gift Article)
Hundreds of new A.I.-generated findings moved the frontiers of higher math in a single day — dispelling any doubt that the field is forever changed.
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Science Magazine @science.org · 05/10/2026
Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. scim.ag/4rTKck8
scim.ag
How did Rosalind Franklin miss the helix in her iconic DNA image? She didn’t
New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51
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Reposted by Rod Rahimi
Science Magazine @science.org · 04/10/2026
A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. Learn more on #WorldAnimalDay: scim.ag/46OMl6v
This odd fish has 30 times as much DNA as humans—a new record for animals
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Rod Rahimi @rodrahimi.bsky.social · 03/10/2026
Congrats on this very cool story!!
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Payal Yokota @payalyokota.bsky.social · 01/10/2026
Why does the same virus kill one host and spare another? The key is lung imprinting from a previous parasitic infection. Our new study @nature.com offers answers + critical mechanisms! Immense thanks to @KamalmKhanna and our collaborators. 🧵 #Diseasetolerance #NAMs www.nature.com/articles/s41...:
nature.com
Type 2 immune history trains lung macrophages for viral disease tolerance - Nature
Type 2 inflammation trains nerve- and airway-associated macrophages to confer disease tolerance against lethal influenza by limiting immunopathology and promoting tissue repair without enhancing viral...
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Waggoner Lab @labwaggoner.bsky.social · 30/09/2026
Local trained immunity in lung-resident macrophages is a mechanism of disease tolerance and a therapeutic entry point for severe inflammatory respiratory infections @nature.com @khannakm.bsky.social @payalyokota.bsky.social www.nature.com/articles/s41...
nature.com
Type 2 immune history trains lung macrophages for viral disease tolerance - Nature
Type 2 inflammation trains nerve- and airway-associated macrophages to confer disease tolerance against lethal influenza by limiting immunopathology and promoting tissue repair without enhancing viral...
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Reposted by Rod Rahimi
Kimberly Beatty @beattylab.bsky.social · 28/09/2026
Please share: OHSU is hiring an Assistant Prof. in the Dept. of Chemical Physiology & Biochemistry. We are looking for a chemical biologist who will apply novel chemical tools in physiological systems. Apply online: www.ohsu.edu/human-resour... (Job # 2026-41667).
ohsu.edu
OHSU Faculty, Physician and Academic Jobs in Oregon
Find higher education faculty, physician and research jobs and build your academic health career at OHSU in Portland, Oregon.
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Mike Sowden @mikeachim.bsky.social · 28/09/2026
I know there is a hell of a lot going on right now. But not all of it is bad. Some is astonishingly good - like the results of this study from June. Cervical cancer is a terribly cruel thing. This might, at long last, be the beginning of the end of it. www.bbc.co.uk/news/article...
BBC News headline "Young women now have 'close to zero' risk of cervical cancer death after HPV jab"
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Rod Rahimi @rodrahimi.bsky.social · 27/09/2026
Image of red “Current Protocols in Molecular Biology” binders
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epithelial mechanics fan club @epimechfc.bsky.social · 27/09/2026
Can mathematics explain how biological patterns are formed? Alan Turing thought so. Join me, @benswedlund.bsky.social, as we explore his reaction-diffusion theory and how it transformed our understanding of pattern formation and self-organisation.
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Vaughn Cooper @vscooper.micropopbio.org · 25/09/2026
FYI to everyone submitting this October NIH cycle You need to re-certify your ScienCV AFTER Sept 26 (tomorrow) for your application or it may not be accepted. Great timing!
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David Tomaz, PhD @dctomaz.bsky.social · 25/09/2026
How the ‘fire amoeba’ withstands temperatures that would kill most complex life | Science | AAAS www.science.org/content/arti... #Extremophiles #Amoeba #Microbiology #CellBiology #Evolution #Astrobiology #Science 🔬🔥🦠
science.org
How the ‘fire amoeba’ withstands temperatures that would kill most complex life
Incendiamoeba cascadensis may survive in volcanic lakes thanks to a static blanket that shields its proteins from the heat
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Richard Sever @richardsever.bsky.social · 25/09/2026
AI discovery of new enzymes "not a breakthrough...a wrinkle on what we know" www.nytimes.com/2026/09/24/s...
nytimes.com
Anthropic’s A.I. Is Teaching Itself Biology. Now It’s Made Its First Discovery.
Scientists at the company announced their first finding: a group of enzymes whose function is unknown.
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Rod Rahimi @rodrahimi.bsky.social · 25/09/2026
"When I skim a chatbot’s response to a question about back pain, I’m intuitively testing its suggestions against my hard-won mental model for how to approach back pain. Could I have developed that if I’d had a robot leading my thinking all along?"🩺🧪
nytimes.com
Opinion | A.I. Has Made Me a Better Doctor. It’s Made Med Students Worse. (Gift Article)
I’m confident in my mastery over what doctors do — and less confident about my continued mastery of an ever-evolving universe of facts.
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Kate Baker @ksbakes.bsky.social · 25/09/2026
We have an open Assistant/Associate Professor position in Pathogen Biology at the Department of Genetics - come and join us! 🦠 🧫 🧬https://www.cam.ac.uk/jobs/assistantassociate-professor-in-pathogen-genetics-pc51175
cam.ac.uk
Assistant/Associate Professor in Pathogen Genetics
Applications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu...
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Doug Kojetin @dougkojetin.bsky.social · 23/09/2026
Apply today to be my colleague at Vanderbilt in the Department of Biochemistry! 
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Harmit Singh Malik @harmitmalik.bsky.social · 21/09/2026
Thanks to the generosity of the Bezos Family Foundation, @basicsci.fredhutch.org is excited to announce a new search to recruit a Bezos Family Distinguished Scholar : apply.interfolio.com/193655
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Thiago Carvalho @cyrilpedia.bsky.social · 20/09/2026
'What these ancient programs were not primarily optimized to handle is the prolonged and repetitive nature of many modern disease states, where inflammatory and repair pathways are engaged continuously over years or decades rather than transiently after injury.' www.cell.com/cell/fulltex...
cell.com
The regulatory logic linking inflammation and fibrosis
Fibrosis is a major contributor to disease and mortality yet lacks effective therapies. This review proposes that fibrotic states are maintained by chromatin-regulated circuits in fibroblasts and macr...
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Rod Rahimi @rodrahimi.bsky.social · 20/09/2026
I think integrin biology and diapedesis make you a card carrying member of the group :) Just added you
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Rod Rahimi @rodrahimi.bsky.social · 20/09/2026
Sure thing, David! My pleasure. Just added you
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Michael Glickman @michaelglickman.bsky.social · 18/09/2026
Incredible Harold Freeman, Who Helped Remove Barriers to Cancer Treatment, Dies at 93 www.nytimes.com/2026/09/15/h...
nytimes.com
Harold Freeman, Who Helped Remove Barriers to Cancer Treatment, Dies at 93
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Rod Rahimi @rodrahimi.bsky.social · 17/09/2026
Of course! Congrats on starting your lab! Excited to see the work from your group
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Rod Rahimi @rodrahimi.bsky.social · 17/09/2026
#Immunology 🧪🩺
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Nature @nature.com · 08/09/2026
Reports that two children died after receiving gene-editing treatments in separate clinical trials in China have put a spotlight on the country’s fast-track trial pathway go.nature.com/46PF7iI
go.nature.com
China’s fast-track clinical trials are in the spotlight after child deaths
A new government policy seeks to balance innovation and safety.
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RyanLab_TCD @ryanlab.bsky.social · 07/09/2026
🚨 We’re hiring a postdoctoral research associate! This is a great opportunity for scientists with a PhD interested in mitochondrial biology, immunometabolism, or primary mitochondrial disease. For more information email: ryand67@tcd.ie and include your CV and cover letter
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Rod Rahimi @rodrahimi.bsky.social · 04/09/2026
“The academic clinicians I interviewed wanted to help identify and pursue the most advanced treatments for their patients — it is, after all, what they understand their duty to be — but felt their hands were tied by the red tape of bureaucracy.”🧪🩺
nytimes.com
Opinion | The Search for New Cures Is Broken (Gift Article)
It is too hard for medical researchers to launch clinical trials.
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c0nc0rdance @c0nc0rdance.bsky.social · 01/09/2026
"Its crucial medical care ratio fell to 86.7% from 89.4% year-over-year..." This means they only spent $86.70 covering medical care for every $100 you paid them. By avoiding paying for medical care, they can rake in ~$24B in profits. What the hell are we doing here? 😕
forbes.com
UnitedHealth Group Profits Hit $5.4 Billion As Insurer Controls Costs
UnitedHealth Group reported second quarter net income of $5.48 billion as medical costs dropped, triggering an improved financial outlook for the rest of the year.
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Jason Shepherd @jasonsynaptic.bsky.social · 31/08/2026
Have neglected my photography the past year. Finally had a moment to breathe and go through some pics from our Milford Sound hike in New Zealand last year. 📷 🏞️
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Roby Bhattacharyya @roby-b.bsky.social · 27/08/2026
To underscore why this is especially awful for those who may not know, the measles vaccine is usually given at 12 months. Newborns rely on community immunity to prevent exposure, which until recently we have had in the US. This quite literally could be anyone's newborn. None of this had to happen.
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Rod Rahimi @rodrahimi.bsky.social · 13/08/2026
🙏
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Rod Rahimi @rodrahimi.bsky.social · 07/08/2026
I’m thrilled and relieved to share that I received the notice of award for our first R01. I’m grateful to the reviewers for being supportive of our work and the NIH staff for all of their efforts. Thankful for the fantastic folks in our lab and excited to continue our work and build the group!
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Rod Rahimi @rodrahimi.bsky.social · 03/08/2026
I created a rule in Outlook that sends any email with “unsubscribe” or other words common to these predatory emails directly into my junk folder. Not perfect but it has really helped decrease these emails in my inbox.
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c0nc0rdance @c0nc0rdance.bsky.social · 01/08/2026
The headlines are still covering the cyclosporiasis outbreak from lettuce, but let's talk about a different summer, long ago. The headlines in Bavaria would have called it "summer diarrhea" & it was killing babies. Enter our hero, Professor Theodor Escherich of the Julius Hospital, Würzburg.
Signed portrait of Theodor Escherich, MD (1857-1911). Dr. Escherich was a German-Austrian pediatrician, best known for his discovery of the Escherichia coli bacterium
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Earl K. Miller @earlkmiller.bsky.social · 15/07/2026
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86 news.mit.edu/2026/mit-pro... #neuroscience
news.mit.edu
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86
Susumu Tonegawa, a renowned MIT professor of biology and neuroscience and a Nobel laureate, has died at the age of 86. His discovery of how the immune system generates many different antibodies earned...
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Rod Rahimi @rodrahimi.bsky.social · 08/07/2026
This is fascinating “curiosity puts the entire brain into a mode of heightened receptivity — not just for the specific thing you want to know, but also for everything around it. Curiosity opens a window, and while the window is open, learning deepens across the board.”🧪
nytimes.com
Opinion | We Are Losing the Ability to Discover What We Didn’t Know to Ask
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Vincent van Unen @vincentvanunen.bsky.social · 03/07/2026
Excited to share our new paper in @mucosalimmunol.bsky.social ! How do CD4 T cells behave directly inside inflamed intestinal tissue in IBD? Find out below 🧵! paper: sciencedirect.com/science/arti...
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Richard Sever @richardsever.bsky.social · 01/07/2026
"Despite years of failure...doubts about what I was doing with my life...years of lackluster results...my PhD research is not a complete waste" Max's story of how we got checkpoint inhibitors should inspire any PhD worried their work's going nowhere theimmunebeyond.substack.com/p/a-brief-hi...
theimmunebeyond.substack.com
A Brief History of Checkpoint Blockade
A major medical breakthrough, interrupted
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NEJM.org @nejm.org · 28/06/2026
In a phase 3, randomized trial involving children with achondroplasia (3 to 17 years of age), once-daily oral infigratinib for 1 year significantly increased the annualized height velocity as compared with placebo. Full PROPEL 3 trial results: nej.md/4w8vTJc #ICCBH2026
A graph from the Original Article "Phase 3 Trial of Oral Infigratinib in Children with Achondroplasia." The trial name, PROPEL 3, is in parentheses next to the title. The graph shows mean change in annualized height velocity from baseline for the Infigratinib and placebo groups. The trial results are being presented at the International Conference on Children's Bone Health. The logo of The New England Journal of Medicine is at the bottom.
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Rod Rahimi @rodrahimi.bsky.social · 24/06/2026
I did this on a recent R01 A1 and there were no issues. I explained in the intro how the title change was in line with reviewer comments from the A0. No issues at study section or council. Still waiting to see if a NOA will arrive though…
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Denis Wirtz @deniswirtz.bsky.social · 22/06/2026
3D reconstruction reveals highly conserved vascular network architecture despite phylogenetic diversity spanning >300M years of evolution. Moer here: www.biorxiv.org/content/10.6...
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Sinem Saka @sinemsaka.bsky.social · 21/06/2026
If you’ve built DNA-barcoded antibody panels, you know the pain: every barcode means another conjugation. In our new preprint we introduce UnO, which transforms antibody conjugation problem into a universal barcode conversion workflow, enabling rapid panel generation. www.biorxiv.org/content/10.6...
biorxiv.org
Universal oligo adapters for high-efficiency DNA-barcoded antibody panel generation
DNA-barcoded antibodies are central to a broad range of spatial and dissociative assays and applications, including multiplexed imaging, single-cell profiling, and proximity detection. Direct modifica...
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Rod Rahimi @rodrahimi.bsky.social · 19/06/2026
"Thus, PD-1 signaling is not simply a brake. It also preserves stemness...therapies such as interleukin-7 that restore or stabilize these renewable compartments may extend the long-term benefit of checkpoint inhibition." 🧪🩺
nejm.org
Stemness as the Engine of Checkpoint Durability | NEJM
The clinical benefits of checkpoint inhibitors in the treatment of cancer often wane. A preclinical study points to a potential strategy for a more durable effect.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 11/06/2026
Reminder — UW #Microbiology has an open search for an Assistant Professor, focusing on fundamental problems in #bacteriology! If you or someone you know would be suitable, here's the ad: apply.interfolio.com/185622
Screenshot of the job listing linked in full above
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Michael Okun @michael-okun.bsky.social · 10/06/2026
Over the last month I saw that human editors are now stripped of control. I could no longer stop the system from auto-inviting "reviewers" with zero relevant expertise. Even worse - the AI began actively revoking the invitations I manually sent out to actual, qualified experts.
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Denis Wirtz @deniswirtz.bsky.social · 12/06/2026
ICYMI, Hopkins will provide $280M in mid-size and large grants to support faculty for 2 years (1) $160M for all life scientists (from basic to bioengineering, from policy to translation) (2) $120M for all science and engineering. This cannot replace federal funding, not even close, but it helps.
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Henry De Belly @henrydebelly.bsky.social · 10/06/2026
Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
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Melody Schreiber @melodyschreiber.com · 01/06/2026
I am BEYOND thrilled to share my article for Public Health mag: Baltimore has cut its homicide rate by almost 60% (!!!!) by supporting those most at risk of suffering from or committing gun violence. Other cities, take note: magazine.publichealth.jhu.edu/2026/baltimo...
magazine.publichealth.jhu.edu
A Contagious Peace: Behind Baltimore’s Historic Homicide Reduction | Hopkins Bloomberg Public Health Magazine
Baltimore cut its homicide rate by 60% from 2021 to 2025—largely through a public health approach to gun violence.
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Rod Rahimi @rodrahimi.bsky.social · 04/06/2026
"Kaminski, Naji and their colleagues have since treated four more people with CAR-T therapy, one of whom received a transplant last month after waiting 20 years for a donor kidney. The team expects to enrol another four people by the end of this year."🧪🩺
nature.com
‘Transformative’ CAR-T therapy allows three people to receive kidney transplants
They had ‘highly sensitized’ immune systems that usually reject donated organs, leaving them with few options for survival.
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Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀 @mackayim.bsky.social · 04/06/2026
After the catch-up in testing, the number of new daily cases has stayed near 20/day. Not rising is a really good thing.
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