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René Inckemann

@reneinckemann.bsky.social
839 followers 495 following 32 posts

interested in plant #synbio, Postdoc @stanford in the Brophy lab, alumni @mpi_marburg @erblabs, @gasb_synbio steering @igemmarburg instructor 2018-2024

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Reposted by René Inckemann
Nick Desnoyer @nickdesnoyer.bsky.social · 31/07/2026
Starting next week we will begin revealing the results of our Flower Bioengineering genetic toolkit, all sponsored and synthesised by @genewiz.bsky.social Here’s a teaser of our first results. Can you guess what gene it is?? 🖤
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Reposted by René Inckemann
Nick Desnoyer @nickdesnoyer.bsky.social · 16/07/2026
Meet Ruby Petunie! Our little alien Petunia growing in tissue culture ❤️🧬
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German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 18/06/2026
Thanks to all the plant scientists, who have tirelessly explained the new genomic techniques (#NGT) besides their workload in the universities, the labs and during their PhD theses! #SciComm Read details on EU’s new rules www.europarl.europa.eu/news/en/pres...
europarl.europa.eu
New genomic techniques for plants to boost innovation in sustainable agriculture | News | European Parliament
Parliament has adopted new rules facilitating access to new plants that are climate and pest resistant, give higher yields and require fewer pesticides.
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Jenn Brophy @jennbrophy.bsky.social · 04/06/2026
Excited to share our new preprint "Genetic code expansion enables plant-directed control of bacterial activity", a fantastic collaboration with @kunjapur.bsky.social lab! www.biorxiv.org/content/10.6...
biorxiv.org
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Tobias Jores @tobiasjores.bsky.social · 30/04/2026
📢Out now on bioRxiv: We used Plant STARR-seq to characterize the species- and condition-specific enhancer activity of over 350,000 sequences derived from four plant species. For more, see below and read the paper at: www.biorxiv.org/content/10.6...
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Axel Visel @axelvisel.bsky.social · 30/04/2026
JGI @jgi.doe.gov is looking for bold partners with expertise in lab automation 🤖, plant transformation 🌱, AI-supported imaging 🔬, and scalable bioengineering 🧬 Goal: build an automated system to identify, select, and process 10k+ transformed plant calluses/day Details: sam.gov/workspace/co...
AI-generated image of pale green plant callus tissue arranged in a Petri dish to form the letters “JGI” and a stylized DNA helix.
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James Lloyd 🧬 @jamespblloyd.bsky.social · 29/04/2026
I am super excited to announce that I am recruiting a new post-doc to join my team at UWA & @plants4space.bsky.social to work on plant synthetic biology, with a focus on genome engineering. If you are interested, please apply or reach out to me. external.jobs.uwa.edu.au/cw/en/job/52...
external.jobs.uwa.edu.au
Prospective staff : Jobs at UWA : The University Of Western Australia
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Kenneth Loi @kenjmloi.bsky.social · 27/04/2026
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.
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German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 02/03/2026
#PlantSciJobs #PlantSciJob 7 PhD positions SMART Plants for Tomorrow’s Needs SMART Plants for Tomorrow’s Needs @ceplas.bsky.social in several locations Deadline: 18 March 2026 www.deutsche-botanische-gesellschaft.de/stellenangeb...
deutsche-botanische-gesellschaft.de
Stellenausschreibungen in Pflanzenwissenschaften und Botanik
Stellenausschreibungen in Pflanzenwissenschaften und Botanik
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James Barrett @james-r-barrett.bsky.social · 30/01/2026
Almost forgot to thank @reneinckemann.bsky.social for helping us set up the chloroplast transformation system we relied so heavily upon! Go read his cool paper here: www.nature.com/articles/s41...
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James Barrett @james-r-barrett.bsky.social · 30/01/2026
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵 Preprint here!: www.biorxiv.org/content/10.6... @cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social #Rubisco #PhaseSeparation #Condensates #Pyrenoid
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René Inckemann @reneinckemann.bsky.social · 01/02/2026
You're welcome! Thanks for the shoutout, and congrats on your super interesting paper.
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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 30/01/2026
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...
science.org
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
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Chenxin Li, PhD @chenxinli2.bsky.social · 24/01/2026
Rational improvement of pennycress using CRISPR. #PlantScience From: www.nature.com/articles/s41...
nature.com
Creating a new oilseed crop, pennycress, by combining key domestication traits using CRISPR genome editing - Nature Plants
De novo domestication was performed on the brassica Thlaspi arvense (pennycress) by identifying and stacking CRISPR-induced mutations to create a new intermediate oilseed crop that can be grown in the...
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Doudna Lab @doudna-lab.bsky.social · 27/01/2026
🚀 New preprint! @jacobsenucla.bsky.social x @doudna-lab.bsky.social collaboration: High-activity TnpB (Ymu1-WFR) + a multi-gRNA system in TRV enables heritable, tissue-culture-free multiplex editing in plants. Big potential for plant biotech 🧬🌾🌱 doi.org/10.64898/202...
doi.org
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Nature Plants @natplants.nature.com · 19/01/2026
New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
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Nick Desnoyer @nickdesnoyer.bsky.social · 19/01/2026
My poster on flower bioengineering at the #AIEBaB26 conference in Bristol last week 🌹 🧬 ✨
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Nick Desnoyer @nickdesnoyer.bsky.social · 16/01/2026
Why I’m genetically engineering a rainbow flower… And how a Russian fairy tale inspired the idea 🧵
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Jess @jessnash.bsky.social · 15/12/2025
Genetic engineering, painting, sculpting, floristry, and fantasy are united in @nickdesnoyer.bsky.social 's flower design art project. New essay out now on a blossoming frontier of transgenic art!
allmovingparts.substack.com
Mutating The Medium
A blooming future for biodesign
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Nick Desnoyer @nickdesnoyer.bsky.social · 15/12/2025
Pleased to share this thoughtful essay by Jess on my flower design project🌹🧬 As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
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CEPLAS - Cluster of Excellence on Plant Sciences @ceplas.bsky.social · 09/12/2025
‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
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German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 08/12/2025
European plant scientists welcome the EU Trilogue Provisional Agreement on New Genomic Techniques (#NGT), as EU-SAGE reports, the network representing plants scientists at 134 European plant science institutes and societies www.eu-sage.eu/news/Europea...
eu-sage.eu
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Andreas P.M. Weber 🌾🌱🧬 @apmweber.bsky.social · 26/11/2025
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file. No RNA-seq. No protein homology. No repeats, hints, or curated evidence. Raw genome → accurate gene models. Deep learning + HMM, published in @natmethods.nature.com www.nature.com/articles/s41...
nature.com
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
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Nick Desnoyer @nickdesnoyer.bsky.social · 21/11/2025
After 10 Fridays, 10 flowers, and 100+ drawings, the Florédex is complete! ✨ Come take a tour of the design and science behind 10 iconic flowers 🌺🧵
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Chenxin Li, PhD @chenxinli2.bsky.social · 10/11/2025
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
A gene regulatory network built from single cell co-expression, orthology, transactivation, and overexpression. The TF IDB1 activates itself the TF IDM1. IDM1 and IDB1 together activates IDM4, which in turn activates biosynthetic genes.
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Nature Plants @natplants.nature.com · 04/11/2025
New OA Article: "A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas" rdcu.be/eOdZP Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
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René Inckemann @reneinckemann.bsky.social · 03/11/2025
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas. Huge thanks to the whole team! www.nature.com/articles/s41...
nature.com
A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas - Nature Plants
This study reports a modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii that allows large-scale characterization of genetic parts and prototyping o...
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James Lloyd 🧬 @jamespblloyd.bsky.social · 31/10/2025
I am delighted to share our latest work on memory gene circuits for plants. This work was led by the phenomenal PhD student @patrickgong.bsky.social A lot of debugging & highlights how even simple components in synthetic biology can have unexpected properties. www.biorxiv.org/content/10.1...
biorxiv.org
CREation of an expanded plant memory gene circuit toolkit
Genetic circuits rely on modular, well-characterized genetic parts to achieve predictable cellular behaviour. Despite their widespread adoption, biological parts are complex and when used in a new mol...
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Nick Desnoyer @nickdesnoyer.bsky.social · 29/10/2025
Don’t miss my presentation @iGEM tomorrow at 14:00 main stage! I will be throwing out bio-designer shirts to the back row 🧬🤘
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Nick Desnoyer @nickdesnoyer.bsky.social · 27/10/2025
Genetically engineered color-changing Arabidopsis 🧬📷- attempt #3 I think I finally nailed it with this one.
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Nick Desnoyer @nickdesnoyer.bsky.social · 24/10/2025
Friday Flower 008: Tulip 🌷 Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look. The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯
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Nick Desnoyer @nickdesnoyer.bsky.social · 22/10/2025
One of my Arabidopsis micro-roses next to its wild type sister ✨ Now just to make it rainbow 🧬...
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Nick Desnoyer @nickdesnoyer.bsky.social · 10/10/2025
Friday Flower 007: Petunia 💮✨ Petunias carry the active transposon dTph1, which powers mutant screens and paints stripey patterns as it jumps. Their five petals are fused, with diverse color designs tracing the corolla’s fusion seam.
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Tung Le @tunglejic.bsky.social · 03/10/2025
Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
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Nature Biotechnology @natbiotech.nature.com · 26/09/2025
A tiny white-petalled weed beloved of plant biologists has received a CRISPR-fueled makeover, turning it into a supersized ruby-colored bloom www.nature.com/articles/s41...
nature.com
Blooms supersized - Nature Biotechnology
Nature Biotechnology - Blooms supersized
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Nick Desnoyer @nickdesnoyer.bsky.social · 21/09/2025
Color changing flowers 🧬🎨- attempt #2 Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..
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Nick Desnoyer @nickdesnoyer.bsky.social · 19/09/2025
Friday Flower 005: Arabidopsis thaliana 🌱✨ A tiny flower, but a giant in research, thale cress enabled our understanding of flower development through the "ABC Model". With this knowledge, their flowers can be essentially reprogrammed to produce micro-roses 🧬🌹
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Nick Desnoyer @nickdesnoyer.bsky.social · 12/09/2025
Friday Flower 004: Hibiscus trionum 🌺✨ Hibiscus trionum displays a dark bullseye in the center that acts as a landing pad for pollinators 🎯 The bullseye is made by a developmental boundary delineating distinct cell shapes and pigments.
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Nick Desnoyer @nickdesnoyer.bsky.social · 11/09/2025
Sneak peak of tomorrows Friday Flower! 🌺 Whoever guesses the flower correctly gets a gold star ⭐️
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Ralf Reski @reskilab.bsky.social · 09/09/2025
W1 Tenure-Track Professor for Plant Biochemistry. Tübingen, Germany. #plantscijobs #plantscijob uni-tuebingen.de/fakultaeten/...
uni-tuebingen.de
JobOpportunities
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Nick Desnoyer @nickdesnoyer.bsky.social · 06/09/2025
The "Florédex" ✨, a pokémon-inspired vector collection of the greatest flower designs and their science is coming along nicely 🌷🧬 All hand-drawn, digitalised, and animated.
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Nick Desnoyer @nickdesnoyer.bsky.social · 05/09/2025
Friday Flower 003: Antirrhinum majus 🐉✨ Snapdragons are icons of floral symmetry. Their corollas are bilaterally symmetrical with dorsal (d), lateral (l), and ventral (v) petals. Mutations in CYCLOIDEA produce peloric flowers with all ventral petals in radial symmetry.
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Nick Desnoyer @nickdesnoyer.bsky.social · 02/09/2025
Flower Butts #BlossomBottoms
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Nick Desnoyer @nickdesnoyer.bsky.social · 02/09/2025
Color changing flowers 🌺 🧬 From pink to white in 3 days. My first Time-lapse at @thesainsburylab.bsky.social
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Nick Desnoyer @nickdesnoyer.bsky.social · 30/08/2025
Inducible RUBY expression in independent transformant lines of A.thaliana over 4 days. Several lines (top) show induction everywhere except the petals... cool but I'd prefer the opposite!!
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Nick Desnoyer @nickdesnoyer.bsky.social · 28/08/2025
New imaging setup for my micro-rose color prototyping 🌸🔬 This design has a wine red (#a53841) center radiating into muted salmon (#d47989) along the fringes ✨ 🧬
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Nick Desnoyer @nickdesnoyer.bsky.social · 29/08/2025
Friday Flower 002: Mirabilis jalapa🌺✨ Four O’Clocks, like other Caryophyllales, produce red (betacyanins) and yellow (betaxanthins) petal sectors through differential regulation of betalain biosynthesis during corolla development.
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René Inckemann @reneinckemann.bsky.social · 22/08/2025
Do you think this system could be transfered into other species?
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Nick Desnoyer @nickdesnoyer.bsky.social · 22/08/2025
Friday Flower 001: Mimulus lewisii 🌸✨ Monkeyflowers are masterpieces of design with nectar-guide spots formed by an activator–inhibitor system of MYB transcription factors. These generate reaction–diffusion patterns across the ventral petal.
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René Inckemann @reneinckemann.bsky.social · 22/08/2025
I already love your "Friday Flower format! Super cool graphics
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