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Ronny Drapkin

@rdrapkin8-penn.bsky.social
281 followers 215 following 51 posts

Professor at the University of Pennsylvania. Director of UPenn Ovarian Cancer Research Center. Our lab focuses on the factors that drive ovarian tumorigenesis - it's totally tubular!

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Ronny Drapkin @rdrapkin8-penn.bsky.social · 22/09/2025
Excited to share the Ovarian Cancer Research Syndicate line-up of speakers for the fall. Please share. We have amazing trainees presenting and the latest from leaders in the field. @powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
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DOD OCA @ocacademy.bsky.social · 21/09/2025
Another inspiring and successful DoD OCA workshop where science, collaboration, and camaraderie come together to push research and care forward.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 21/09/2025
A friend shared this article: www.nytimes.com/2025/09/14/m... The public needs to know!
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 19/09/2025
Thank you to the #CanaryFoundation for hosting our ovarian pre-cancer atlas team meeting this week. We are excited to start working on Atlas 2.0!
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 18/07/2025
Great trip to the UK for the British Gynecologic Cancer Society meeting and a visit to @ox.ac.uk Oxford University. Thank you to Drs. Manchanda and Ahmed for the invites. Beautiful and historic places.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 10/07/2025
Beautiful morning in London. Excited to attend the 2025 British Gyn Cancer Society #BGCS meeting.
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Lynda Steele 🇨🇦 @steeletalks.bsky.social · 22/06/2025
If you are opposed to vaccinating your kids and don't think measles is a serious disease - please read this. Your decisions affect not only your family - but everyone they interact with. www.nytimes.com/2025/06/22/u...
nytimes.com
‘I Feel Like I’ve Been Lied To’: When a Measles Outbreak Hits Home
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 30/05/2025
Delighted and honored to receive a Pershing Square grant to support our work in ovarian cancer and to attend the award ceremony in NYC! t.co/m6QnLqjuQD @pennmedicine.bsky.social @penncancer.bsky.social @upenn.bsky.social @billackman.fanpeeps.com
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 22/05/2025
It was an absolute honor and delight to deliver the 2nd Annual Erin Rothfuss lecture Johns Hopkins today. Getting to meet the family made it extra special. Thank you to Amanda Fader for the invitation and the opportunity to connect with so many Hopkins colleagues!
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Eric Topol @erictopol.bsky.social · 21/05/2025
New @nature.com An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer www.nature.com/articles/s41...
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Jack Iwashyna @iwashyna.bsky.social · 08/03/2025
NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social
g.co
Google Search
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Elizabeth McKenna @elizsmckenna.bsky.social · 13/05/2025
Now online in Cancer Discovery: Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets - by Vindhya Vijay, Negin Karisani, Gad Getz, Nabeel Bardeesy, and colleagues doi.org/10.1158/2159...
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Jim Hurley @jimhurley.bsky.social · 14/05/2025
mTORC1 is activated when cells are fed with amino acids. New preprint with @robzonculab.bsky.social led by Rachel Jansen shows how the massive "CastiGATOR" complex is formed when arginine-free CASTOR1 binds to the GATOR2 complex to antagonize mTORC1 starved cells. tinyurl.com/yr6en6f4
Cryo-EM structure of CASTOR1-GATOR2 complex
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Denis Wirtz @deniswirtz.bsky.social · 07/05/2025
We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/05/2025
Our first NIH ovarian cancer SPORE team mtg with our @hopkinsmedicine.bsky.social partners since our successful renewal! Thanks to our EAB/IAB members for their time & insights. Great day of science! Thanks to Yelena for all the invaluable help. @deniswirtz.bsky.social @penncancer.bsky.social
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Wonder of Science @wonderofscience.bsky.social · 04/05/2025
The speed of light visualized on a cosmic scale. Credit: Dr James O'Donoghue
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 02/05/2025
Does this include CRUK-NIH Cancer Grand Challenges (RFA currently open)? @cancergrand.bsky.social www.nature.com/articles/d41...
nature.com
Exclusive: NIH to end billions of dollars in foreign research grants
Move by US biomedical agency jeopardizes thousands of projects on infectious diseases, cancer and more.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 30/04/2025
Thanks for the opportunity @onclive.bsky.social!
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Elizabeth McKenna @elizsmckenna.bsky.social · 29/04/2025
Online now in Cancer Discovery concurrent with Victor Velculescu's #AACR25 presentation on next-gen liquid biopsies for early detection: Detection of Brain Cancer Using Genome-Wide Cell-Free DNA Fragmentomes doi.org/10.1158/2159...
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C.H. Romatowski @chromatowski.bsky.social · 29/04/2025
Periodic reminder this is FDA-approved for men as well as women up to age 45! It covers 9 strains of HPV so even if you’ve been exposed to some, it can protect you from others. It works on strains that cause cervical, vaginal, vulvar, anal, throat and back of mouth cancer. Low-key medical miracle.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 29/04/2025
Another great #AACR meeting! Great energy, incredible science, and wonderful opportunity to connect with former trainees, colleagues, and collaborators. @ocacademy.bsky.social
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 24/04/2025
Wonderful to celebrate Dr. Patrick Sung from @utsanantonio.bsky.social as the Basser Global Prize Awardee and keynote speaker at the 2025 Basser Center for BRCA Symposium!
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 27/03/2025
Surprising findings of BRCA mutations on the Fallopian tubes. Result of a tremendous team effort with @shenhui1986.bsky.social @vainstitute.bsky.social, Chuck Drescher @fredhutch.bsky.social, and Jarrod Marto @danafarber.bsky.social. @pennmedcso.bsky.social www.nature.com/articles/s41...
nature.com
Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube - Nature Communications
The human Fallopian tube (FT) is implicated as a site of origin for pelvic serous cancers. Here the authors conduct multi-omics analysis on over 100 FTs. The results challenge the assumption that BRCA...
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Jeremy Berg @jeremymberg.bsky.social · 21/03/2025
New article out in The Dispatch thedispatch.com/article/nih-... 1/n
thedispatch.com
The Costs of Research Funding Delays at NIH
How a weeks-long freeze of the grant review process has stymied a myriad of scientific studies.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 21/03/2025
Celebrating first-author papers with mugs from #ScienceGrit (sciencegrit.com). Congrats to Matt Knarr and Pamela Rojas de Santiago!
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Jacob T. Levy @jacobtlevy.bsky.social · 19/03/2025
Excellent excellent excellent from Princeton president and constitutional/ political theorist Chris Eisgruber. There's been far too little of this kind of thing; here's hoping others follow his good example. www.theatlantic.com/ideas/archiv...
theatlantic.com
The Cost of the Government’s Attack on Columbia
American universities have given the country prosperity and security. The Trump administration’s attack on academic freedom endangers all of that.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 17/03/2025
The impact of COVID and the death of public health. What will happen when the next pandemic hits? Another great article by #DrSidMukherjee Covid’s Deadliest Effect Took Five Years to Appear www.nytimes.com/2025/03/10/o...
nytimes.com
Opinion | Covid’s Deadliest Effect Took Five Years to Appear
What once belonged to all of us now belongs to corporations.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 17/03/2025
apnews.com/young-scient...  Young scientists see career pathways vanish as schools adapt to federal funding cuts.
apnews.com
Young scientists see career pathways vanish as schools adapt to federal funding cuts
Reductions to federal support for research at universities and other institutions under President Donald Trump are dimming young scientists’ prospects, cutting off pathways to career-building projects...
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 16/03/2025
"From cutting research funding to attacking free speech, the Trump administration has declared war on colleges. The United States is going through its own cultural revolution." x.com/i/status/190...
x.com
Fareed Zakaria on X: "From cutting research funding to attacking free speech, the Trump administration has declared war on colleges. The United States is going through its own cultural revolution. My take: https://t.co/zpQ5WnyFNS" / X
From cutting research funding to attacking free speech, the Trump administration has declared war on colleges. The United States is going through its own cultural revolution. My take: https://t.co/zpQ5WnyFNS
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Nature Portfolio @natureportfolio.nature.com · 16/03/2025
Aspirin may enhance the immune response against cancer metastasis in mice, according to research published in Nature. The authors suggest that the findings could aid the development of effective anti-metastatic immunotherapies. go.nature.com/3F3GWOB 🧪
This is figure 5, which shows that aspirin promotes anti-metastatic immunity by releasing T cells from ARHGEF1-dependent suppression by TXA2.
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Harmit Singh Malik @harmitmalik.bsky.social · 13/03/2025
Current mood
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Emil Lou, MD, PhD, FACP, FASCO @cancerassassin1.bsky.social · 12/03/2025
From Forbes magazine: “NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report“ www.forbes.com/sites/michae...
forbes.com
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 13/03/2025
The House of Representatives just passed a CR that includes devastating cuts to the Congressionally Directed Medical Research Program (CDMRP) – 57% cut. It is absolutely critical that we reach out to our Senators now and urge them NOT to include these cuts. Call them!
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Mike Feigin 🥯 @mikefeigin.bsky.social · 11/03/2025
Holy. Fucking. Shit.
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Science Magazine @science.org · 11/03/2025
A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵)
Science Advances’ special issue on women’s health highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Articles cover a range of studies from the interplay between menopause and Alzheimer’s risk to the menstrual cycle’s influence on the brain-heart connection. It also describes the opportunities pregnancy provides to research aspects of both physical and mental health. By prioritizing women’s unique physiological and psychological experiences, research can expand the frontiers of knowledge in ways that benefit everyone.
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Eric Topol @erictopol.bsky.social · 11/03/2025
Genome editing success for the first time in nine patients with alpha-1 antitrypsin deficiency, a heritable disease which can cause cirrhosis and emphysema, affecting ~100,000 Americans, which is similar to the prevalence of sickle cell disease www.nytimes.com/2025/03/10/h...
nytimes.com
Mutated DNA Restored to Normal in Gene Therapy Advance
The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions.
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Eric Topol @erictopol.bsky.social · 10/03/2025
Who funds biomedical research? @nature.com www.nature.com/articles/d41...
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
This is an excellent video that explains NIH funding and indirect costs. Super important to understand this. It is critical funding: youtu.be/NtqK8SyxFMc?...
youtu.be
Facilities and Administrative (F&A) Costs Explainer
YouTube video by Association of American Universities
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
Congratulations to Pamela Rojas de Santiago on her paper in @Nature_NPJ Precision Oncology showing LINE-1 ORF1p expression in clear cell ovarian cancer precursors (endometriosis) and detection in patient samples. 🎉 rdcu.be/ecv6k @powelldrescher.bsky.social @tinaswish.bsky.social @srocf.bsky.social
rdcu.be
LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker
npj Precision Oncology - LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
Standing up for Science at Philly City Hall! Who would have thought we'd have to do this?!? Science serves society! Science is diverse! Science saves lives! America is great because of science! "If you stand for nothing, you will fall for anything!" #StandUpforScience2025
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
Rally for Science!
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
Standing up for Science at Philly City Hall!!
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 07/03/2025
Super important!
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Roel Verhaak @roelverhaak.bsky.social · 01/03/2025
New preprint from the lab - Selective depletion of cancer cells with extrachromosomal DNA via lentiviral infection www.biorxiv.org/content/10.1...
biorxiv.org
Selective depletion of cancer cells with extrachromosomal DNA via lentiviral infection
Extrachromosomal DNA (ecDNA), a major focal oncogene amplification mode found across cancer, has recently regained attention as an emerging cancer hallmark, with a pervasive presence across cancers. W...
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 28/02/2025
Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10: Cancer Cell www.cell.com/cancer-cell/...
cell.com
Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10
Lee et al. show that neutrophil extracellular traps (NETs) establish the pre-metastatic niche in the omentum by recruiting innate-like B cells and eliciting IL-10 production in these cells through ina...
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Claudio Ballabio @claballabio.bsky.social · 26/02/2025
Did you know cancer cells can be electrically active, just like neurons? This electrical activity plays a key role in tumor progression. Excited to share my first postdoc paper at @crick.ac.uk (and first paper from Leanne Li lab), published in @natureportfolio.nature.com!
nature.com
Intrinsic electrical activity drives small-cell lung cancer progression - Nature
Electrical excitability in neuroendocrine SCLC cells promotes tumour progression through action potential firing, increasing ATP demand and oxidative phosphorylation dependency, whereas non-neuroendoc...
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Science News @scinews.bsky.social · 20/02/2025
🎯Breaking News Enzyme used in meiosis makes the cut in vitro News www.nature.com/articles/d41... Paper 1 doi.org/10.1038/s415... Paper 2 doi.org/10.1038/s415... Paper 3 doi.org/10.1038/s415...
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E John Wherry @ejohnwherry.bsky.social · 18/02/2025
Outstanding thread on university endowments! I would encourage all faculty anywhere to read this.
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