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Rachel Gregor

@rachelgregor.bsky.social
795 followers 753 following 12 posts

Assistant Professor at the University of Toronto in Chemical Engineering and Applied Chemistry. Fascinated by microbial communities and their chemistry. www.gregorlab.com

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Reposted by Rachel Gregor
Phil Knutson, PhD @philknutson.bsky.social · 01/10/2026
Lignin chemistry!! I’ve drawn a line tree with the lignin polymer behind it. I’ve drawn it as one single polymer throughout! This messy, highly irregular biopolymer gives plants structural strength and helps protect their cell walls. #sciart #chemsky
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shenvi.bsky.social @shenvi.bsky.social · 01/10/2026
A few folks have asked how I make molecular animations from ChemDraw. Sadly, the answer has been “the old-fashioned way,” frame by frame. This was too slow. So I worked with Claude Science to create a webpage that animates your ChemDraws. Give it a try: rshenvi.github.io/cdxmorph/
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Will Ratcliff @wcratcliff.bsky.social · 15/09/2026
1/17 Submissions are now open for the 2027 Microbial Population Biology GRC! We expect this meeting to be extraordinarily oversubscribed. If you want to come, time is of the essence--apply ASAP! June 27–July 2 • Andover, NH www.grc.org/microbial-po...
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MEEhubs @meehubs.bsky.social · 05/08/2026
What, is it over already? MEEHubs2026 concluded just minutes ago. It's been a blast, and here are some stats for you: 711 registrations, 241 posters, 71 talks, 3 days, participants from 32 countries. Bye from all the hubs 🩵🩵🩵 #MEEHubs2026 #MEEHubs26
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Rachel Gregor @rachelgregor.bsky.social · 05/08/2026
Just after wrapping an amazing three days in Montreal, I can say that I highly recommend organizing a hub! Hope to see you all again in 2028
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Cameron Thrash @jcamthrash.bsky.social · 22/05/2026
Nutrient environments shape amino acid auxotrophy and cross-feeding www.biorxiv.org/content/10.6... #jcampubs
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Sara Mitri @saramitri.bsky.social · 22/05/2026
Check out our pre-print led by the fantastic Massimo Amicone, collaborating with the Bollenbach lab! tinyurl.com/4h9p8mfb We build a simple intuition on how ecological interactions affect resistance evolution by expanding evolutionary rescue theory and testing it with two large sets of experiments
tinyurl.com
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Markus Eichhorn @markuseichhorn.bsky.social · 07/05/2026
Bingo! Do I win a prize now?
Comic strip titles self-sabotaging academic habits that feel normal, featuring nine panels.
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Reposted by Rachel Gregor
Sean Gibbons 🦠💩 @gibbological.bsky.social · 24/04/2026
Looks interesting 🤓: "Community context reshapes microbial proteomes and reduces functional overlap" @natmicrobiol.nature.com www.nature.com/articles/s41...
nature.com
Community context reshapes microbial proteomes and reduces functional overlap - Nature Microbiology
Biotic interactions modulate protein abundance, reducing functional redundancy and increasing productivity in complex bacterial communities.
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Sara Emery @saraemery.bsky.social · 27/03/2026
job alert. 🧪👩‍🔬🌍🌐🌱🐞🦠🦔
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Life Science Network @lifesciencenet.bsky.social · 27/03/2026
Understanding how “marine snow” acts as a carbon sink. #science #news www.lifescience.net/news/7083/un...
lifescience.net
Understanding how “marine snow” acts as a carbon sink
A new study finds hitchhiking bacteria dissolve essential ballast in ubiquitous “snow” particles, which could counteract the ocean’s ability to sequester carbon.
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Jason Rasgon @vectorgen.bsky.social · 23/03/2026
OK folk I need some advice. We have a microbiome pub that we're having trouble getting published (not even getting to the review stage-being bounced editorially as "not mechanistic") Large paper, 11 figures + supplement Where is a good venue these days to publish "descriptive" microbiome studies?
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Center for Chemical Currencies of a Microbial Planet (C-CoMP) @microbialplanet.bsky.social · 23/03/2026
So excited to share our newest paper on #marine #exometabolites. A great effort led by Yuting Zhu, Hanna Anderson, and others in the C-CoMP team www.pnas.org/doi/10.1073/...
pnas.org
Characterization of phytoplankton-excreted metabolites mediating carbon flux through the surface ocean | PNAS
The marine labile dissolved organic carbon (DOC) pool is a dynamic reservoir of thousands of molecules that cycles approximately one-quarter of Ear...
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Reposted by Rachel Gregor
Leon-Samuel Icking @lsi.bsky.social · 23/03/2026
🧬 Please repost 🧬 I was asked to organise a panel discussion for a SynBio Student Meetup in Hamburg in the middle of May and I'm still looking for panellist! If you know any researchers at the PhD/Postdoc who have expertise in metabolic/genome/multicellular organism engineering, please reach out!
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Colin Carlson @colincarlson.bsky.social · 23/03/2026
‼️ New preprint: By solving a paradox in graph theory, we show that specialist symbionts constrain ecosystem structure, drive biodiversity, and face high extinction risk. With @jbyoder.org and @ctrlalttim.com: 🎉 Specialists drive biodiversity scaling in symbiotic relationships
Sublinear and linear scaling coexist in bipartite graphsReal ecological networks are constrained by the presence of specialistsCoextinction risk is driven by host extinction risk - but especially high for specialists
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Tami Lieberman @contaminatedsci.bsky.social · 18/03/2026
If you're a senior PhD student or recent graduate interested in doing work at the intersection of AI and microbial genomics and/or microbiomes, please feel free to reach out to discuss the possibility of applying together for an MIT Novo Nordisk Fellowship engineering.mit.edu/novo-nordisk
engineering.mit.edu
Novo Nordisk Fellowship
Potential areas of focus for postdoctoral fellows participating in the MIT-Novo Nordisk Postdoc Program include, but are not limited to, the following: Your complete application should include: In the...
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Nature @nature.com · 18/03/2026
A chemist, physicist, and biologist walk into a bar go.nature.com/3PfmrDS
go.nature.com
Knock knock, no one’s there. Study finds scientists’ jokes mostly fall flat
Survey examines how often academics attempt jokes during conference talks — and how these attempts at comedy land.
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Paul Carini @uncultured.carinilab.com · 19/03/2026
Is there a consensus for ANI differences associated with Order, Family, or Genus level divergence in bacteria? I'm looking at ~79% ANI between two genomes and am wondering where that falls.
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AI x Bio Discovery @aixbiobot.bsky.social · 19/03/2026
GAP-MS: Automated validation of gene predictions using integrated mass ‎spectrometry evidence [new] Confirms protein accuracy, filters errors, identifies missing genes in complex plant genomes, resolving annotation ambiguities.
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Cameron Thrash @jcamthrash.bsky.social · 18/03/2026
Characterization of phytoplankton-excreted metabolites mediating carbon flux through the surface ocean www.pnas.org/doi/abs/10.1... #jcampubs 🌊
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Rachel Gregor @rachelgregor.bsky.social · 18/03/2026
Coming this August 3-5 to a hub near you (Switzerland, USA, Canada, Mexico, UK, Ukraine, or virtual only)! #Microbiome #MicroSky
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MEEhubs @meehubs.bsky.social · 18/03/2026
MEEHubs2026 registration and abstract submission is now online! 🚨🦠✨ Join us Aug 3 - 5, 2026 at one of the 7 hubs or online. We are incredibly excited about our lineup of speakers, and hope that you submit an abstract to contribute too! More information and registration links at: meehubs.org
meehubs.org
Home
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Tami Lieberman @contaminatedsci.bsky.social · 28/02/2026
One of my favorite papers of past few years!
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Ran Blekhman @blekhman.bsky.social · 02/03/2026
AI has huge promise for genomics -- but it has consistently failed at microbiome-based prediction. My new post on why simple models keep winning, where deep learning actually earns its place, and where the field is headed blekhman.substack.com/p/ai-keeps-f...
blekhman.substack.com
AI Keeps Failing at Microbiome Prediction
Why simple models keep winning, where deep learning still shines, and where the field is headed
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Charlotte Houldcroft @virologyhouldcroft.bsky.social · 18/03/2026
Have you ever wondered why children starting nursery/daycare pick up so many germs? I certainly did, and with a crack team of parent-scientists/clinicians, we set out to answer that question. Is childcare a germ factory or an immune bootcamp? journals.asm.org/doi/10.1128/...
journals.asm.org
Germ factories or immune boot camps? Infection and immunity in childcare settings | Clinical Microbiology Reviews
SUMMARYChildcare outside the home is a common experience for many children in high-income countries. It is associated with an increase in the incidence of infectious diseases—not just for the child bu...
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Dr. Sue Ishaq @drsueishaq.bsky.social · 16/03/2026
Paper published on preserving microbiomes to secure health in degrading ecosystems! I'm delighted to announce a new publication on the importance of preserving microbiomes to secure health in degrading ecosystems! The paper outlines strategies for preserving critical microbes, functions, and…
sueishaqlab.org
Paper published on preserving microbiomes to secure health in degrading ecosystems!
I'm delighted to announce a new publication on the importance of preserving microbiomes to secure health in degrading ecosystems! The paper outlines strategies for preserving critical microbes, functions, and microbial communities using some specific examples, and ties these back to opportunities and challenges to making conservation efforts. This paper was a collaborative effort by several members of the Microbiome Stewardship…
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Reposted by Rachel Gregor
Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 25/02/2026
In case you missed it: our review titled "Spatial structure: shaping the ecology and evolution of microbial communities" is out! 🚨 Let me hit you with some highlights on why spatial structure matters. (and why you should care!) Sharing is appreciated 🙏 🧵👇 doi.org/10.1093/fems...
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Sean Gibbons 🦠💩 @gibbological.bsky.social · 26/02/2026
"Can you trust the results from gut microbiome tests? Maybe not." www.sciencenews.org/article/resu... I understand why the authors didn't disclose the different company IDs...but I'm very curious to know which is which
sciencenews.org
Can you trust the results from gut microbiome tests? Maybe not
Seven firms reported inconsistent results on the same sample, some over multiple tests. These gut microbe discrepancies could have health consequences.
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nicoleeavalon.bsky.social @nicoleeavalon.bsky.social · 20/02/2026
The MIBiG 5.0 Annotathon is coming soon, and registration is now open! 🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise. Register here 👉 forms.gle/C1cWcLHtrjT2...
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Nature Biotechnology @natbiotech.nature.com · 19/02/2026
Harnessing microalgae for the biosynthesis of molecular crystals - @bengurionuniv.bsky.social go.nature.com/3MxVqui
go.nature.com
Harnessing microalgae for the biosynthesis of molecular crystals - Nature Biotechnology
Crystalline materials for optical applications are synthesized in living dinoflagellates.
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Dr Laura Sanchez @drlaurasanchez.bsky.social · 05/02/2026
Hey all, excited to share this collab w/ @shaunmckinnie.bsky.social TL;DR we combined our expertise to develop and validate a MALDI-tims platform for screening the production of isomeric small molecules (~212 Da) directly from E coli colonies in high throughput www.cell.com/cell-reports...
cell.com
A high-throughput biocatalytic platform for screening isomeric kainoid natural products
Shepherd and Ramachandra et al. present a fast, chromatography-free method for resolving isomeric products from engineered enzymes. This platform enables large-scale screening and identifies improved ...
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Reposted by Rachel Gregor
Vardilab @vardilab.bsky.social · 05/02/2026
🌊Paper announcement! 📣 Viral infections rewire the metabolic makeup of their host and thereby create distinct chemical signatures. Can we use metabolic biomarkers to diagnose infections of algal blooms in the ocean? Well, take a look at our new article led by Conny Kuhlisch in @pnas.org >>
doi.org
Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | PNAS
The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events ...
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Cat Manning @catacalypto.bsky.social · 21/12/2025
another example of AI as tracer dye, exposing an already existing problem (and, of course, significantly worsening it)
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Frank Santoriello @fsantoriello.bsky.social · 21/12/2025
The final form of my 2nd postdoc paper with the Bassler Lab! Turns out our favorite quorum-sensing phage isn’t a one-off, but rather a member of a globally dispersed family of phages that sense a universal autoinducer. #phagesky #microsky journals.asm.org/doi/10.1128/...
journals.asm.org
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species | mBio
The discovery of quorum-sensing responsive linear plasmid phages has transformed understanding of phage-bacterial interactions by demonstrating inter-domain chemical communication. To date, however, e...
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Richard Lenski @relenski.bsky.social · 19/12/2025
"The changing roles of Escherichia coli" -- a short essay by yours truly. rdcu.be/eVtXT
rdcu.be
The changing roles of Escherichia coli
Nature Microbiology - Richard Lenski traces the legacy of Escherichia coli and how science is evolving to use this model organism in new ways.
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 18/12/2025
Enjoyed reading “AI for chemistry in 2025 is like AI for images in 2010” leashbio.substack.com/p/ai-for-che...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 16/12/2025
Phosphorus stress and spatial confinement lower the threshold for quorum-sensing activation of redox-active metabolite production in Pseudomonas synxantha bioRxiv from Dianne Newman www.biorxiv.org/content/10.1...
biorxiv.org
Phosphorus stress and spatial confinement lower the threshold for quorum-sensing activation of redox-active metabolite production in Pseudomonas synxantha
Bacteria often coordinate collective behaviors such as biofilm formation and secondary metabolite production through quorum sensing (QS), a regulatory system traditionally linked to high cell density....
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Stem Cell Network @stemcellnetwork.ca · 17/12/2025
📢 NEW exciting opportunity! Join Queen’s University as a tenure-track Assistant Professor in Cell Engineering and Biomanufacturing, with opportunities for interdisciplinary research across #ChemicalEngineering and #Biomedical and #MolecularSciences. 🔬 🔗 stemcellnetwork.ca/career-oppor...
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Dan Udwary @danudwary.secondarymetabolism.com · 15/12/2025
DOE's Office of Science is making a big push into AI, and that includes our work at the @jgi.doe.gov . We want to hear your thoughts (+ and -) on AI-enabled biological data. Consider joining one of our interviews or focus groups by filling out this form! 🧪🧬🦠🖥️ #secmet jointgeno.me/PortalStorie...
jointgeno.me
Tell Us Your JGI Portal Stories
The JGI Portal teams (IMG, Mycocosm, Phycocosm, Phytozome, and SMC) would love to sit with you (over Zoom) to hear your stories relating to your usage of the portals, your unsupported use cases, and p...
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Eryk Salvaggio @eryk.bsky.social · 14/12/2025
It’s good to see papers start to address LLMs as structural plagiarism — provenance, more hidden than the original words or training data. www.nature.com/articles/s42...
nature.com
LLM use in scholarly writing poses a provenance problem
Nature Machine Intelligence - LLM use in scholarly writing poses a provenance problem
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Mitja M. Zdouc @mmzdouc.bsky.social · 11/12/2025
Have you ever used a #bioinformatics #database and were frustrated by its lack of coverage? Did you ever think about starting your own resource? We just published a new strategy for community-driven #biocuration, based on our experiences with the #MIBiG database (1/8)! doi.org/10.1093/bib/...
doi.org
Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0
Abstract. Biocuration is essential to transform molecular sequence data into standardized, machine-readable resources. Such curated datasets enable compara
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 09/12/2025
What started out as a structure-function project for an undergraduate researcher morphed into something bigger w/ @popea.bsky.social leading the way. Check out how RhlR fine tunes its response to its autoinducer to avoid producing too much pyocyanin. www.biorxiv.org/content/10.6...
biorxiv.org
RhlR quorum-sensing receptor ligand sensitivity regulates the differential expression of phenazine genes in Pseudomonas aeruginosa
Bacteria control individualistic and group behaviors using a form of cell-cell communication called quorum sensing. Quorum sensing relies on the production of chemical signals called autoinducers and ...
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Mizrahi Lab @mizrahilab.bsky.social · 09/12/2025
In our new paper in @natcomms.nature.com We discovered how Ruminococcus bromil organizes and regulates its enzyme complex to efficiently break down resistant starch, forming a key metabolic foundation for the human gut ecosystem. (1/12) 📄 www.nature.com/articles/s41...
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BejaLabTechnion @bejalab.bsky.social · 08/12/2025
Our BEHIND THE STORY. A glimpse into the role of auxiliary metabolic genes in cyanophages during infection communities.springernature.com/posts/a-glim...
communities.springernature.com
A glimpse into the role of auxiliary metabolic genes in cyanophages during infection
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Bob Lynn @boblynn.bsky.social · 30/10/2025
Angelina Fanny Hesse: The Woman Who Brought Agar from the Kitchen to the Laboratory voxmeditantis.com/2025/10/30/a... #WomenInSTEM #STEM #Microbiology #Agarology #Bacteriology
voxmeditantis.com
Angelina Fanny Hesse: The Woman Who Brought Agar from the Kitchen to the Laboratory
Angelina Fanny Hesse reveals how childhood memories of Indonesian pudding solved bacteriology’s greatest problem in 1881. The unpaid laboratory technician whose kitchen knowledge enabled Koch…
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Uri Alon @urialonlab.bsky.social · 03/12/2025
We analyzed changes in physiology relative to menopause using two large scale studies that include millions of lab tests. Rather than align by age, we used statistical inference to align tests to final menstrual period. (1/2) arunamed.com/the-menopaus...
arunamed.com
The Menopause Cliff: What a Million Women's Lab Tests Reveal
TLDR: A massive study of 300+ million lab tests from 1+ million women just proved what women have been saying for years: menopause isn't a gradual slope—it's a physiological cliff. Nearly e
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Sara Mitri @saramitri.bsky.social · 03/12/2025
Amazing dataset describing the metabolic profiles of 66 E. coli transporter knockouts by @sulheim.bsky.social with Peter Doubleday and @nzamboni.bsky.social. The tool, set up by @lambdapp.bsky.social and Eric Ulrich allows you to explore for yourself. Enjoy! Pre-print here: doi.org/10.1101/2025...
doi.org
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Snorre Sulheim @sulheim.bsky.social · 03/12/2025
Do you think transporters in E. coli contribute to metabolite release? No? Explore the effect of 66 different transporter knockout mutations on the exometabolome dynamics of ~300 metabolites yourself: keio.unil.ch Teaser: Increased proline in ΔputP #microsky #MEvoSky
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