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Jon Paczkowski🌹

@paczkowskilab.bsky.social
265 followers 406 following 45 posts

PI|Wadsworth Center|NYS Department of Health Assoc. Prof.|Biomedical Sciences|UAlbany Using structural biology (PhD|Fromme Lab|Cornell) & genomics to decode bacterial chatter (JCC Fellow|Bassler Lab|Princeton) Flower grower & cat rescuer Views are my own

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Reposted by Jon Paczkowski🌹
Zeynep Baharoglu @zeynepbaharoglu.bsky.social · 03/06/2026
Extended Shine-Dalgarno motifs govern translation initiation in Staphylococcus aureus www.nature.com/articles/s41... 🦠
nature.com
Extended Shine-Dalgarno motifs govern translation initiation in Staphylococcus aureus - Nature Communications
Kohl et al. combine high-resolution Ribo-seq and cryo electron microscopy to show that the bacterium Staphylococcus aureus uses extended Shine-Dalgarno motifs to initiate translation, which can make…
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 04/06/2026
Wonderful write-up about my colleague Nick Mantis at the Wadsworth Center and his fantastic MS and PhD students @albany.edu: www.albany.edu/cihs/news/20... It's tick season. Be on the look out in your garden and on your nature walks!
albany.edu
Immune Response to Lyme Disease: Research at the New York State Department of Health’s Wadsworth Center
Spread by the blacklegged tick, Lyme disease is caused by the bacterium Borrelia burgdorferi and can lead to fever, rash, facial paralysis, irregular heartbeat, arthritis and other symptoms. UAlbany s...
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 09/05/2026
Tremendous scholarship on display by our students @albany.edu, including Hannah from the Ciota Lab in our Department of Biomedical Sciences! www.albany.edu/news-center/...
albany.edu
Five UAlbany Graduate Researchers Receive SUNY GREAT Awards for Research Excellence
Five graduate students from the University at Albany have been named recipients of the State University of New York’s Graduate Research Empowering and Accelerating Talent (GREAT) Award. The recognitio...
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Reposted by Jon Paczkowski🌹
Stella Hurtley @smhsci.bsky.social · 17/04/2026
Out now in @science.org Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape | Science www.science.org/doi/10.1126/...
science.org
Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape
Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In m...
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Reposted by Jon Paczkowski🌹
Rep. Melanie Stansbury (NM-01) @repstansbury.bsky.social · 14/04/2026
For all those still feeling the moon joy—Artemis II was brought to you by public schools and publicly funded science. Copy that! 👩‍🚀🚀💕 *All four astronauts went to public schools!
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 07/04/2026
New in JB: In the CF airway, P. aeruginosa transitions from an acute to chronic pathogen. Roxana Flores-Vega, Roberto Rosales-Reyes et al. review the role of 2-component systems in this crucial adaptation. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
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Reposted by Jon Paczkowski🌹
Guim Aguadé-Gorgorió @guimaguade.bsky.social · 07/04/2026
Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests journals.plos.org/ploscompbiol...
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 02/04/2026
Caleb is so deserving of this fellowship, as are many of our trainees across the country. We are grateful for the support and I am so incredibly proud of him. Here's to many more publications on the proteolytic targeting of quorum-sensing receptors.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 01/04/2026
A true labor of love for @calebmallery.bsky.social is out now in PLOS Pathogens: a review article where we highlight current and emerging examples of key protein-protein interactions with LuxR-type receptors that control community behaviors and pathogenesis. journals.plos.org/plospathogen...
journals.plos.org
Expanding the LuxR-type receptor functional repertoire: Protein-protein interactions in quorum sensing regulation
Quorum sensing (QS) enables bacteria to coordinate gene expression in response to population density, with LuxR-type transcription factors playing a central role in this process for many Gram-negative...
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Reposted by Jon Paczkowski🌹
Grainger Lab @graingerlab.bsky.social · 24/03/2026
Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com www.jobs.ac.uk/job/DQY475/r...
jobs.ac.uk
Research Fellow (Postdoctoral) at University of Birmingham
Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.
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Reposted by Jon Paczkowski🌹
Mar Hicks @histoftech.bsky.social · 06/02/2026
No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition. Which just makes me want to share it again: www.nature.com/articles/d41...
nature.com
Gladys Mae West obituary: mathematician who pioneered GPS technology
She made key contributions to US cold-war science despite facing huge barriers as a Black woman.
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Reposted by Jon Paczkowski🌹
John Greally @greally.bsky.social · 05/02/2026
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine. faculty-einstein.icims.com/jobs/17847/a...
faculty-einstein.icims.com
Albert Einstein College of Medicine | Medical Education | Biomedical Research
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 04/02/2026
rince & JB Editor's Choice: Lin, Prince & Feaga identified sporulation genes via analyzing almost 1500 genomes. They show that that an unusual membrane-localized variant of Spo0B is found throughout Paenibacillaceae. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
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Reposted by Jon Paczkowski🌹
Nadia Nikulin, PhD @nadianikulin.bsky.social · 03/02/2026
First paper of my PhD @doerrlab.bsky.social is up! We characterized meropenem tolerance in Enterobacterales species, and then further dissected tolerance mechanisms in Klebsiella pneumoniae. journals.plos.org/plospathogen...
journals.plos.org
Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae
Author summary Bacteria can survive exposure to antibiotics by constantly repairing cellular damage induced by the drug. This “antibiotic tolerance” enables diverse bacteria to survive long enough to ...
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Reposted by Jon Paczkowski🌹
Dana Shaw @shawlab.bsky.social · 02/02/2026
My department at Washington State University is recruiting an Assistant or Associate Professor in vector-borne disease 🕷️🦟🦠 Full job description is linked below. Come join us on the Palouse!
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 02/02/2026
Former mentee @ksimanek.bsky.social is not only a great scientist, they're also a tremendous advocate for equity in science. I am very proud of Kayla and of this piece they put together. Check it out. asm.org/articles/202...
asm.org
Navigating Academia: Inclusion and Parity for LGBTQIA+ Scientists | ASM.org
What can be done to address the modern and historical challenges faced by queer scientists? Matt Welch, Ph.D., and Bruno Lima, Ph.D., offer insights.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 26/01/2026
Please help spread the word about this tremendous undergraduate research opportunity taking place in Albany this summer! www.albany.edu/rna/reu-in-rna
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 26/12/2025
Tremendous work by Swati, @calebmallery.bsky.social, and @nilesh-banavali.bsky.social, partially from Caleb's rotation in Nilesh's lab!
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Reposted by Jon Paczkowski🌹
plasmidsaurus @plasmidsaurus.bsky.social · 22/12/2025
This dino’s in mint condition! Seasonally striped for optimal performance.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 22/12/2025
For students and early career professionals with an interest in public health, but don't know where to start: the NYS DOH has several internship opportunities. Mentors, please spread the word. These opportunities are open and set to begin in Spring 2026 (February 2-May 8). #publichealth
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 19/12/2025
You buy one protocols book for your lab and Springer thinks they have you all figured out.
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Reposted by Jon Paczkowski🌹
Mike Feigin 🥯 @mikefeigin.bsky.social · 11/12/2025
Petition for a NY Biomedical Institute. This is a no-brainer to support science in NY, similar to programs in CA/TX. www.change.org/p/support-a-...
change.org
Sign the Petition
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
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Reposted by Jon Paczkowski🌹
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 09/12/2025
RhlR quorum-sensing receptor ligand sensitivity regulates the differential expression of phenazine genes in Pseudomonas aeruginosa www.biorxiv.org/content/10.64898/20…
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 09/12/2025
What started out as a structure-function project for an undergraduate researcher morphed into something bigger w/ @popea.bsky.social leading the way. Check out how RhlR fine tunes its response to its autoinducer to avoid producing too much pyocyanin. www.biorxiv.org/content/10.6...
biorxiv.org
RhlR quorum-sensing receptor ligand sensitivity regulates the differential expression of phenazine genes in Pseudomonas aeruginosa
Bacteria control individualistic and group behaviors using a form of cell-cell communication called quorum sensing. Quorum sensing relies on the production of chemical signals called autoinducers and ...
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 18/11/2025
The University at Albany Biomedical Sciences Department is hiring at the Assistant Professor level. We are looking for researchers at the intersection of infectious disease and artificial intelligence: albany.interviewexchange.com/jobofferdeta... #infectiousdisease #artificialintelligence
albany.interviewexchange.com
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 08/09/2025
It is rare as an editor to get to take on an article so uniquely in your wheelhouse. Sharing some wonderful work by Guarnaccia et al. from the Perez, Ng, and Neiditch labs. #structuralbiology of #pathogens @plos.org dx.plos.org/10.1371/jour...
dx.plos.org
Structure-function studies of Vibrio cholerae quorum-sensing receptor CqsR signal recognition
Author summary Quorum sensing, a form of bacterial cell-cell communication, regulates diverse developmental behaviors. This study investigates CqsR, a transmembrane receptor in Vibrio cholerae, the ga...
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Reposted by Jon Paczkowski🌹
Nicole Dubilier @nicoledubilier.bsky.social · 23/08/2025
I missed this when it came out last September - excellent essay! Not-so-mutually beneficial coral symbiosis: Current Biology www.cell.com/current-biol...
cell.com
Not-so-mutually beneficial coral symbiosis
The partnership between corals and their intracellular algal symbionts has long been a textbook example of mutually beneficial association. In this essay, Mikhail Matz argues for an updated view in which the coral acts more as a farmer of algal cells to support its own growth.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 22/08/2025
I have an R56 that will pay for 1 year of a postdoc that will hopefully bridge us to a 4-year R01. It's not without risk but uh...everything in science feels like a major risk right now. We're in need of a #postdoc w/ #nmr experience. DM or email me for project details.
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Reposted by Jon Paczkowski🌹
Vaughn Cooper @vscooper.micropopbio.org · 21/08/2025
Our Pitt Microbiology and Molecular Genetics department in the School of Medicine is recruiting.. Microbiologists! 🧫🦠🔬🧪 Please apply to join our faculty and enjoy these views 👀 while doing great science cfopitt.taleo.net/careersectio...
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Jolene Ramsey @jrrmicro.bsky.social · 05/08/2025
Jon Paczkowski neighbors induce switch two-faced outcome toggled on factor protected #sciku 🧪🧬🔬🧫🦠 #Phages2025
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 16/07/2025
I am (optimistically) looking for a postdoc with solution state biomolecular NMR expertise to join our group. I can provide access to high-end instrumentation and technical assistance via our membership at the New York Structural Biology Center. #nmr #academicsky #postdoc
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Reposted by Jon Paczkowski🌹
Laura Mike @lauraamike.bsky.social · 01/07/2025
Our paper reporting a highly conserved mechanism by which arginine positively regulates hypervirulent K. pneumoniae mucoid phenotype is now fully online. rdcu.be/euiWG Summary picture is below, but details in the 🧵
Overview of paper revealing role of arginine in regulating K. pneumoniae mucoidy.
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Siân Owen @sianowen.bsky.social · 28/05/2025
Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/... Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
Disco lights
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 03/06/2025
www.asmcareerconnections.org/job/research... 12-month hard salary. 100% focus on research and training. Chance to join a microbiology-focused department (viral and bacterial).
asmcareerconnections.org
Research Scientist 5, G-31 Job Opening in Albany, New York - American Society for Microbiology Career Connections
A new Research Scientist 5, G-31 job is available in Albany, New York. Check it out on American Society for Microbiology Career Connections.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 03/06/2025
The Wadsworth Center, New York State Department of Health, is currently recruiting for a Research Scientist 5 (Assistant/Associate Professor equivalent) to lead an independent research program focused on zoonotic and/or vector-borne pathogens (viral and bacterial).
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 01/04/2025
Baseball, and why it's the most beautiful sport ever created.
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 20/03/2025
The meme channel in our lab Slack should be re-named the PI roast channel.
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Reposted by Jon Paczkowski🌹
Coleen Murphy @ctmurphy1.bsky.social · 07/03/2025
#standupforscience2025
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Tim Mosca (he/him) @drosophilosophy.bsky.social · 07/03/2025
Philly is out in full force to Stand Up for Science!!
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Stand Up for Science! @standupforscience.net · 07/03/2025
2 HOURS & 30 MINUTES TO GO! #standupforscience2025
Lincoln memorial in the background with stand up for science posters in the foreground
Lincoln memorial with sound equipment
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Reposted by Jon Paczkowski🌹
Armelle Rancillac 🔬 @rancillac.bsky.social · 07/03/2025
#StandUpForScience Science not silence!
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Mallory Harris, PhD @malar0ne.bsky.social · 07/03/2025
Getting ready to #StandUpForScience in Washington, DC
Sign that says "this is how the next pandemic starts."
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 06/03/2025
Looking for a postdoctoral position in mycobacterial cell-cell contact communication? Look no further! Join my colleagues, Todd Gray and Keith Derbyshire, at the Wadsworth Center: healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
healthresearch.wd1.myworkdayjobs.com
Research Affiliate I (Post Doctoral)
Applications to be submitted by March 14, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $61,008.00 - Maximum: $61,008.00 Annually Department (OPH) WADS - Wadsworth...
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 18/12/2024
A Salmonella enterica serovar Typhimurium Genome-wide CRISPRi Screen Reveals a Role for Type 1 Fimbriae in Evasion of Antibody-Mediated Agglutination www.biorxiv.org/content/10.1101/202…
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 31/12/2024
Long shot (feel free to share), but are you or someone you know an engineering student in the Albany area looking for work? @sianowen.bsky.social and I are hiring someone to do a custom instrument build and a little microbiology with us. Part-time, hourly work that fits your schedule this semester.
healthresearch.wd1.myworkdayjobs.com
Hourly Laboratory Technician I
Applications to be submitted by January 06, 2025 Compensation Grade: H96 Compensation Details: Minimum: $17.85 - Maximum: $17.85 Hourly Department (OPH) WADS - Wadsworth Center Job Description: Respon...
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Vivek Mutalik @vivekmutalik.bsky.social · 22/12/2024
From Peter Fineran Lab academic.oup.com/nar/advance-...
academic.oup.com
Genome-wide identification of bacterial genes contributing to nucleus-forming jumbo phage infection
Abstract. The Chimalliviridae family of bacteriophages (phages) form a proteinaceous nucleus-like structure during infection of their bacterial hosts. This
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Reposted by Jon Paczkowski🌹
Mart Krupovic @mkrupovic.bsky.social · 21/12/2024
Very glad to see our story on the choreography of #ESCRT proteins in #archaeal cell division finally published in mBio - Junfeng Liu et al "A relay race of ESCRT-III paralogs drives cell division in a hyperthermophilic archaeon" journals.asm.org/doi/10.1128/...
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eLife @elife.bsky.social · 21/12/2024
Published in March, this video comes from research that aimed use #CryoET to demonstrate how FtsZ filaments are recruited into a ring or “toroidal” structure as part of a bacterial cell’s division machinery. #12DaysOfeLife buff.ly/3BBCDIY
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Clay Fuqua @fuquaclay.bsky.social · 18/12/2024
Check out the ASM 10th Conference on Biofilms Bluesky page @asmbiofilms2025.bsky.social
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Jon Paczkowski🌹 @paczkowskilab.bsky.social · 17/12/2024
Me and my collaborator 1 hour before the grant is due to the grants office.
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