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Pengyao Jiang

@pyjiang.bsky.social
586 followers 218 following 9 posts

New AP at MechofEvolution of ASU. PhD @Uchicago EE. postdoc at Kelley__Harris lab. Evolution, mutation rate, robustness, yeast, fly, genetics, and genomics. pyjiang.github.io opinion of my own

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Reposted by Pengyao Jiang
Qiyun Zhu @zhuqiyun.bsky.social · 11/12/2025
The scikit-bio paper in online in Nature Methods! Many thanks to our collaborators, community contributors and reviewers! We couldn’t have done it without you. www.nature.com/articles/s41... #Bioinformatics #OpenSource
nature.com
Scikit-bio: a fundamental Python library for biological omic data analysis - Nature Methods
Nature Methods - Scikit-bio: a fundamental Python library for biological omic data analysis
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Maitreya Dunham @maitreya.bsky.social · 25/11/2025
New preprint with @pyjiang.bsky.social and @kelleyharris.bsky.social! The discovery and patterns of the underlying long-standing mild-effect mutator alleles in S. cerevisiae populations www.biorxiv.org/content/10.1...
biorxiv.org
The discovery and patterns of the underlying long-standing mild-effect mutator alleles in S. cerevisiae populations
Most mutations are neutral or deleterious, and mutator alleles that increase the mutation rate of an organism are considered rare and short-lived. Here, we report a genomic signature consistent with t...
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Reposted by Pengyao Jiang
Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 03/09/2025
Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!
genetics-gsa.org
Homepage - Population, Evolutionary, and Quantitative Genetics Conference
Visit our website to learn more.
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Pengyao Jiang @pyjiang.bsky.social · 03/09/2025
Our annual symposium is now open for registration! This year’s theme is Unicellular Diversification of Cell Types and Division. Abstract closes on Oct 1st.
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CanFunNet @canfunnet.bsky.social · 03/06/2025
Abstract submission is still open until June 13th for CanFunNet's virtual meeting! Register here: conference.has.uwo.ca/Register/def...
Poster advertising CanFunNet and the plenary speakers/
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Pengyao Jiang @pyjiang.bsky.social · 03/06/2025
What
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Joshua Weitz @joshuasweitz.bsky.social · 31/05/2025
How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)
NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.
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Dan Garisto @dangaristo.bsky.social · 30/05/2025
From over 300k to less than 100k. A picture of smaller, reduced science.
Estimates for # of people involved in NSF activities
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Eric Topol @erictopol.bsky.social · 31/05/2025
"If the proposal is enacted, Americans today and tomorrow will be sicker, poorer, and die younger” an $18 Billion cut Only 3 NIH Institutes will remain in place, and even they will have their funds markedly reduced www.statnews.com/2025/05/30/n...
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Carl T. Bergstrom @carlbergstrom.com · 27/05/2025
The Republican administration has halted all student (and postdoc etc) VISA interviews. I've written a lot about soft power here. The attacks on foreign students in the US not only undercuts the funding stream for US universities; they hemorrhage US soft power.
politico.com
Trump team pauses new student visa interviews as it weighs expanding social media vetting
It’s the latest salvo against universities, many of whom rely heavily on foreign students for funds.
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Jeff Spence @jeffspence.github.io · 23/05/2025
Another incredibly shameful move from the Trump administration. Upending the lives of so many young people to score cheap political points is absolutely unconscionable. www.nytimes.com/2025/05/22/u...
nytimes.com
Trump Administration Says It Is Halting Harvard’s Ability to Enroll International Students
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Kelley Harris @kelleyharris.bsky.social · 21/05/2025
. @pnas.org just published the final version of our manuscript on how generation time and effective population size interact to shape vertebrate germline mutation rates, led by Luke Zhu and Annabel Beichman: www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Ferric Fang, MD @fangferric.bsky.social · 19/05/2025
“Cutting basic science doesn’t save money.”
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Michael Baym @baym.lol · 14/05/2025
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
A screenshot of the termination notice showing "Outstanding Investigator Grants"A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted
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Senator Bernie Sanders @sanders.senate.gov · 13/05/2025
Trump’s war on science is an attack against anyone who has ever loved someone with cancer. The American people do not want us to slash cancer research in order to give more tax breaks for billionaires.
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 11/05/2025
Lux Capital providing funding opportunities for academic biomedical research aligned with interests 👏 www.luxcapital.com/news/our-hel...
luxcapital.com
Our Helpline for American Scientists
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Thomas Lin Pedersen @thomasp85.com · 07/05/2025
I am excited to share a new version of svglite for #rstats with the world. It includes support for all the new features in the graphics engine as well as providing a more powerful and polished experience for embedding web fonts in the file. Read all about it her:
tidyverse.org
svglite 2.2.0
A new release of svglite has arrived, and with it full support for all the latest capabilities of the R Graphics Engine. Further, it finalizes the new approach to handling web fonts and font embedding...
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Gina Baucom @gbaucom.bsky.social · 06/05/2025
If you care about the NSF and science, now is the time to make your voice heard! The evolution tri-societies are running a Week of Action for NSF! We MUST make some noise -join us!! @sse-evolution.bsky.social members will see the below email in their inbox today, spread the word! Pls RT!
The NSF as we know it is being dismantled. This is a tragedy for science and has the potential to gut the fields of evolution, systematics and ecology. It is time for each of us to loudly speak up in support of scientific funding and in support of the NSF in particular.

The Society for the Study of Evolution, the American Society of Naturalists, and the Society of Systematic Biologists are running a Week of Action for NSF. Your engagement is crucial.
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 05/05/2025
EU augments opportunities for scientists around the world to launch or re-launch their careers in Europe.
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Dr. Suzanne Le Menestrel @drsl.bsky.social · 02/05/2025
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants. www.spencer.org/grant_types/...
spencer.org
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
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Richard Lenski @relenski.bsky.social · 02/05/2025
Deep cuts to EPA, CDC, FDA, NIH, NSF, NOAA, USDA, education & more will damage health and shorten life spans, especially w/ cuts to healthcare for those w/ limited means. Is this the goal, to reduce "entitlements" by killing people? Well, it sure won't make the wealthy any more comfortable.
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Alba Nieto Heredia @albanietoh.bsky.social · 25/04/2025
So Happy for the warm welcome or our PopGen bookclub! Each month, at IBE, we review a new chapter of @gcbias.bsky.social book, which is totally open-source! We encourage you to take a look at it! Link: github.com/cooplab/popg...
github.com
GitHub - cooplab/popgen-notes: Population genetics notes
Population genetics notes. Contribute to cooplab/popgen-notes development by creating an account on GitHub.
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Albert Vilella, PhD. @albertvilella.bsky.social · 20/04/2025
Trump proposes massive 44% NIH budget cut and reorganization | Science | AAAS www.science.org/content/arti...
science.org
Trump proposes massive NIH budget cut and reorganization
Will Republican-led Congress support a 44% decrease for world’s largest medical research funder?
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Noam Ross @noamross.net · 19/04/2025
🚨Report your NSF grant terminations! 🚨 We are starting to collect information on NSF grant terminations to create a shared resource as we have for NIH. The more information we collect, the more we can organize, advocate, and fight back! Please share widely! airtable.com/appGKlSVeXni...
NSF Grant Termination Information Collection Form

Please use this form to submit information identifying specific NSF grants that have been cancelled for any reason after January 20, 2025.


We are tracking these grants to increase transparency, organize affected PIs, and facilitate responses, including via litigation. Please share the form as widely as possible with your networks. 


We are actively building a pipeline to organize these terminations and will soon have a tracker akin to our NIH grant tracker at https://airtable.com/appjhyo9NTvJLocRy/shrNto1NNp9eJlgpA


WE WILL NOT DISCLOSE THE IDENTITY OF ANYONE WHO USES THIS FORM TO PROVIDE INFORMATION. We will keep your identity confidential.


These resources are maintained by Noam Ross of rOpenSci and Scott Delaney of the Harvard T.H. Chan School of Public Health, with input and support from additional volunteers. For any questions, please contact Scott Delaney on Signal (sdelaney.84).


THANK YOU FOR YOUR ASSISTANCE!
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Saccharomyces Genome Database @yeastgenome.bsky.social · 02/04/2025
Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out! meetings.cshl.edu/courses.aspx...
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Ran Blekhman @blekhman.bsky.social · 19/03/2025
Chilling to see this list of terminated NIH grants. Research on Alzheimer's, HIV, rare diseases, vaccines -- gone. Cancer centers closed, training grants & fellowships terminated. Young scientists stranded. Patients waiting for treatments that'll never come. Just sad. taggs.hhs.gov/Content/Data...
taggs.hhs.gov
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闵娅(Min Ya; Minya) PhD @minyaaa.bsky.social · 23/02/2025
There’s a google doc trying to keep track of funding/grad school admission/hiring freezes & status please share 🧪 docs.google.com/spreadsheets...
docs.google.com
Graduate Reductions Across Biomedical Sciences (2025)
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Eric Topol @erictopol.bsky.social · 10/03/2025
Who funds biomedical research? @nature.com www.nature.com/articles/d41...
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Jeremy Berg @jeremymberg.bsky.social · 07/03/2025
Bluetorial: The announcement to move scientific review out of the institutes and centers into the Center for Scientific Review (CSR) and its potential consequences
media.tenor.com
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
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Joshua Weitz @joshuasweitz.bsky.social · 05/03/2025
Science impacts communities nationwide. Ongoing efforts by the WH to dismantle American leadership in science will ripple outwards: risking lives, well-being, and the economy. Stand Up For Science - March 7, 2025 #standupforscience2025 standupforscience2025.org/local-event-...
#standupforscience2025 map of events
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Alisa Bokulich @alisabokulich.bsky.social · 03/03/2025
Proud that the Philosophy of Science Association @philsci.bsky.social is among the signatories of this letter, organized by the Union of Concerned Scientists (UCS), to members of Congress demanding they protect federally funded scientific research & federal scientists. I hope more join. #HPS #STS 🧪
ucsusa.org
48 Scientific Societies Representing Almost 100,000 Scientists Ask Congress to Protect the Future of Science
48 scientific societies representing almost 100,000 scientists signed on to a letter asking Congress to protect the future of science
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Stephanie Hicks @stephaniehicks.bsky.social · 27/02/2025
Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH 🧬🧪 🖥️ 🧠 www.science.org/content/arti...
science.org
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
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Jeremy Berg @jeremymberg.bsky.social · 26/02/2025
ATTENTION The Washington Post is collecting data about funding issues. Please consider contributing. thewashingtonpost.formstack.com/forms/scient...
thewashingtonpost.formstack.com
Are you a scientist who has lost funding or grants in recent weeks? - Formstack
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Christian Landry @christianlandry.bsky.social · 23/02/2025
We are looking for a postdoc in #EvolutionarySystemsBiology. Exciting science, amazing team, wonderful city! landrylab.ibis.ulaval.ca/research-opp... #evolution #synbio #systemsbiology #genomics
landrylab.ibis.ulaval.ca
Research opportunities | Landry Lab
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NPR @npr.org · 22/02/2025
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
npr.org
NIH funding freeze stalls applications on $1.5 billion in medical research funds
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
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Science Magazine @science.org · 19/02/2025
A freeze on meetings of expert panels that peer review grant proposals at the National Institutes of Health is kicking in this week. Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
scim.ag
Trump Tracker: Firings, lawsuits, and U.S. science in chaos
Follow President Donald Trump’s impact on U.S. research and science globally
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Prosanta Chakrabarty @prosanta.bsky.social · 18/02/2025
From NSF’s website: ‘Our investments account for about 25% of federal support to America's colleges and universities for basic research: research driven by curiosity and discovery.’ More than 95% of NSF’s budget goes back out the door to fund science. Cutting staff won’t save much tax payer money.
NSF by the numbers

$9.06B
NSF's Fiscal Year 2024 enacted budget
93%
Percent of budget supporting research, education and related activities
1,900+
Organizations supported by NSF across every state and U.S. territory
350,000+
Researchers, entrepreneurs, students and teachers supported by NSF
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Senator Patty Murray @murray.senate.gov · 16/02/2025
Trump & Elon are putting lifesaving research on life support with a massive funding cut based on an uninformed and illegal whim. Every Senate Democrat is joining me in demanding HHS stop the political games and allow researchers to keep up their important work, uninterrupted.
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Katie Sandlin @kmsandlin.bsky.social · 14/02/2025
I maxed out my credit card, emptied my savings account, and took out a loan to move from Alabama to Bethesda, MD. I don’t even qualify for unemployment since I’ve only worked at NIH for a month. I will be financially and medically devastated. Seeking suggestions for anywhere that’s hiring!!
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Jeremy Berg @jeremymberg.bsky.social · 14/02/2025
(Sorry I took a brief timeout for uncontrollable weeping) In other NIH news, I have heard from multiple sources that NIH plans to fire most, if not all, probationary employees this afternoon. The numbers I am hearing are >5000. Lots of folks extramural staff, intramural scientists, etc.
media.tenor.com
a man with glasses and a mustache is making a sad face
ALT: a man with glasses and a mustache is making a sad face
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Judith Mank @judithmank.bsky.social · 06/02/2025
Genome architecture and speciation in plants and animals. I learned a lot writing this with @dortizba.bsky.social, Silu Wang and Loren Rieseberg! doi.org/10.22541/au....
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Kevin M. Kruse @kevinmkruse.bsky.social · 09/02/2025
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic. globalnews.ca/news/9793403...
globalnews.ca
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
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Elizabeth Warren @warren.senate.gov · 08/02/2025
Instead of cutting costs for working families, Donald Trump is slashing the federal investments that fund their lifesaving care, fuel their local economy, and lower their health care costs. It’s cruel, short-sighted, and will cost jobs and devastate millions of families.
washingtonpost.com
NIH cuts billions of dollars in biomedical funding, effective immediately
Researchers say it would hurt facilities that work on medical issues such as cancer research and heart disease. Elon Musk contends the old policy was ‘a ripoff.’
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Senator Patty Murray @murray.senate.gov · 08/02/2025
This is what amounts to an ILLEGAL & indiscriminate funding cut for research centers everywhere. It will mean shuttering labs across the country, layoffs in red & blue states, and derailing lifesaving research on everything from cancer to opioid addiction. We all need to speak out to save lives.
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Arghavan Salles, MD, PhD @arghavansallesmd.medsky.social · 08/02/2025
To add to this excellent thread, an entire ecosystem is needed for someone like me to carry out research. My current NIH grant pays for a research associate, part of my salary (this is required), and a few consultants. It does not pay for my office space, the grant manager who..
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Wanhe Li @xseedling.bsky.social · 06/02/2025
Dear All, I believe that this thread will become one of my most important contributions to the fly field (I hope I will make other contributions)! Here, I introduce the Soy Milk Machine Fly Food Method, a.k.a., DeepCook!#Drosophila#NewPI
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Pengyao Jiang @pyjiang.bsky.social · 07/02/2025
😱
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 30/01/2025
Really appreciate Jonathan Lambert pointing out that NSF grants are congressionally mandated to weigh how grants broaden participation in science, putting the administration's executive order against DEIA in conflict with, and potentially undermining, congressional legislation
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Rebecca Solnit @rebeccasolnit.bsky.social · 28/01/2025
If you can go, go. 5pm today. Last night's cutoff of federal funding by 47 doesn't just mess with the recipients, it violates the Constitution and seizes powers that belong to Congress. It's a dictatorial attempt at consolidation of power in the presidency. www.mobilize.us/climateactio...
mobilize.us
WHITE HOUSE RALLY · VizEvents
The White House has just frozen federal funding, a move that could halt payments within days to states and households relying on essential programs like SNAP food aid, housing assistance, education, h...
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Senator Ed Markey @markey.senate.gov · 28/01/2025
Trump is unconstitutionally freezing federal funds that Congress sent our constituents and dismantling the democratic system. This isn't business as usual—Congress needs to stop it. I will not support any Trump nominee who will do his illegal bidding. I urge my colleagues to join.
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