We have 45 days to express our opposition to catastrophic changes.

Nature Reviews Immunology, Published online: 08 April 2026; doi:10.1038/s41577-026-01288-0This Review provides an integrated overview of Kupffer cell biology, from their embryonic origin and spatial organization to their functional specialization within the liver. It emphasizes how Kupffer cells act as immune sentinels while also shaping metabolic regulation, tissue repair, infection and cancer and discusses how emerging technologies are refining our understanding of their context-dependent roles across physiological and pathological settings.

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Pre-existing antibodies restrict naive B cell entry into germinal centers, but how antibody feedback shapes ongoing reactions is unclear. In this issue of Immunity, Barbulescu et al. and Yan et al. sh...

Do you struggle with the blank page? These strategies could help.

Taking to the stage to present your science is a key part of research, but talks often fall flat, says John Tregoning. Can scientists learn from performers to better engage an audience?

YouTube video by American Society for Microbiology

The leading annual all-immunology event worldwide!

YouTube video by xkcd's What If?

YouTube video by American Society for Microbiology

NextGen Immunologists Day welcomes undergraduate students into the immunology community through a full day of hands-on learning, scientific exploration, and meaningful connection.

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Ant queens of one species clone ants of another to create hybrid workers that do their bidding.