New study uncovers how genetics influence children’s cognitive ability as they age.

Nature Human Behaviour, Published online: 10 July 2026; doi:10.1038/s41562-026-02491-8Associations between polygenic indices and cognitive ability in children increase with age while rare damaging variant associations attenuate, with differential effects across the cognitive ability distribution.

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Autism is a highly heritable neurodevelopmental condition that manifests across a wide phenotypic spectrum. Rare and de novo loss-of-function mutations strongly predispose to autism and co-occurring d...

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

Patients with neurodevelopmental conditions without a monogenic diagnosis have a higher polygenic burden than those with a monogenic diagnosis. Non-transmitted common all...

Genetic factors influence vulnerability to common mental health conditions, but their role in early-life mental health remains understudied. We analysed genotype array and exome sequence data from two...

Genetic factors influence vulnerability to common mental health conditions, but their role in early-life mental health remains understudied. We analysed genotype array and exome sequence data from two...

Studying the genetics of intelligence can help us understand the neurobiology of cognitive function and the aetiology of rare neurodevelopmental conditions. The largest previous genetic studies of int...

Here the authors analyze de novo mutations in >10,000 parent-offspring trios and find that ancestry and smoking independently associate with mutation rate, but that common genetic variants likely c...

Autism is four times more prevalent in males than females. To study whether this reflects a difference in genetic predisposition attributed to autosom…

Research Associate x 2 (Fixed Term) in the Department of Psychiatry at the University of Cambridge.

Nature Medicine - In a cohort of 50,556 South Asian individuals, partitioned polygenic scores helped identify genetic susceptibility to insulin deficiency and unfavorable fat distribution as key...

In rare diseases, rare mutations have long been thought of as the only contributor. Genetic analyses of people with such conditions now suggest that the effects of common genetic variants can stack up and contribute to disease risk. Assessing the influence of common mutations on rare disease risk.

Patients with neurodevelopmental conditions without a monogenic diagnosis have a higher polygenic burden than those with a monogenic diagnosis. Non-transmitted common all...

Sanger Prize competiton 2025 for undergraduates interested in genomics, who are from low- and middle-income countries