Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Nature Reviews Genetics, Published online: 03 November 2025; doi:10.1038/s41576-025-00914-2In this Journal Club, Peter Koo reflects on the 2021 publication of Enformer and its impact on the use of deep learning for modelling the regulatory genome.

Nature Methods - Benchmarking genomic language models

The in-person component will be held at the New York Genome Center, 101 6th Ave, New York, NY 10013. All times below are Eastern Time.

Background The emergence of genomic language models (gLMs) offers an unsupervised approach to learning a wide diversity of cis-regulatory patterns in the non-coding genome without requiring labels of ...

The 20th Machine Learning in Computational Biology (MLCB) meeting will be a two-day hybrid conference, September 10-11, 9am-5pm ET, with the in-person component at the New York Genome Center, NYC. Reg...

Youtube channel for the Machine Learning in Computational Biology conference: https://mlcb.github.io/

Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.

Lentivirus-based reporter assays for 680,000 regulatory sequences from three cell lines coupled to machine-learning models lead to insights into the grammar of cis-regulatory elements.

Despite extensive mapping of cis-regulatory elements (cREs) across cellular contexts with chromatin accessibility assays, the sequence syntax and genetic variants that regulate transcription factor (T...

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