Embarrassed, she initially didn’t want to report attack. Maricopa County Sheriff’s Office's investigation is ongoing.

The landmark release of 722 papers targeting 372 unsolved problems draws amazement—and criticism

Contribute to openai/math development by creating an account on GitHub.

Cell-type-specific, time-locked release of the opioid neuropeptide dynorphin in the dorsomedial striatum is both necessary and sufficient for goal-directed behavior. Inputs from the basolateral amygda...

Single-nucleus RNA sequencing and spatial validation across human and mouse striatum define principles of neuronal specialization across cell types, subregions, and species. These findings lay the fou...

Large-scale cortical dynamics during natural behavior are difficult to measure because head-mounted imaging systems must balance field of view, spatial resolution, weight, and optical complexity. Exis...

The prize recognizes Henri Kagan and Kenso Soai's discovery of non-linear effects and autocatalysis in asymmetric organic synthesis

The US science-funding agency is withholding $1 billion of its budget so that the money can go to a special White House project.

The merger of two of Hollywood's biggest movie studios comes after months of legal disputes and concern over competition

Francis Halzen is a leader in the study of neutrinos, ghostly particles from across the universe that hint at exciting new physics

Supramolecular polymers with precise micrometer-scale segments of opposite charge are challenging to synthesize as discrete assemblies in water. These systems could be used to pattern charged surfaces...

Stories of science funding being cut, labs shutting down and scientists losing jobs have flooded the media under Trump's administration. These six graphics show how those changes have affected U.S. bi...

Drug-associated sensory cues and contexts exert powerful influence over drug seeking motivation, but in vivo brain mechanisms governing this process remain unclear. Here, we recorded and manipulated d...

Optogenetics has come in for some stick lately, with a number of people criticising the hype that this technique generates in some quar...

Yakubovskaya et al. show that motion adaptation shifts macaque IT population codes for object position in a direction that mirrors human perceptual mislocalization. Current feedforward, recurrent, and...

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Mouse experiments show that Alzheimer’s disease and corticobasal degeneration tau filaments retain their distinct structures during templated seeding, supporting strain-specific tau propagation and disease modelling.

Intrinsic timescale reflects the temporal window of neural processing, but how it matures across the human cortex during development remains unclear. This study shows that intrinsic timescale develops...

arXiv, and the scientific community at large, are facing a watershed moment. Scholarly publishing is currently changing at a rapid pace, and we are seeing a…

ALT: Seriously

The U.S. President discussed the war in Iran, press freedom, AI, and more ahead of the midterm elections.

Faini et al. develop CLOK, a method that labels neurons across a spectrum of colors according to when they were born, allowing successive generations of brain cells to be tracked as they take shape in...

Clonal barcoding across the newborn mouse forebrain reveals developmental principles whereby glutamatergic neurons and astrocytes remain locally derived, whereas widely dispersed GABAergic (γ-aminobut...

A strategy for functional G-protein-coupled receptor (GPCR) antagonism through bispecific antibody-mediated endocytosis and lysosomal degradation is reported.

Chen et al. show that SCN2A protein-truncating variants disrupt cortico-striatal circuitry while increasing neuronal excitability in human brain assembloids. CAV-2-mediated SCN2A restoration mitigates...

Unexpected patterns traveling across the human brain may be reorganizing its activity in real time.

Li et al. present OpenFISH, an open, cost-effective imaging-based spatial transcriptomics platform with single-cell resolution that enables same-section MALDI-MSI integration. OpenFISH maps inflammato...

It’s the first documented outbreak of bird flu in captive mink in the U.S., and an advocacy group is raising concerns about Utah’s response.

In this study, Luppi et al. systematically characterized and modeled more than 6,000 features of neural activity during anesthesia. They reveal a shared but reversible dynamical endpoint of anesthesia...

ALT: Reaction Cute

Liu et al. identify a population of Lef1+ hypothalamic neurons that coordinates feeding and thermogenic adaptations to cold. Cold suppresses Kcnk2/TREK-1 function to enhance neuronal activity, reveali...

Cornford et al. show that exponentiated gradient (EG) learning, which updates synapses multiplicatively, matches gradient descent on cognitive tasks while respecting Dale’s law and producing brain-lik...

RT&T-AMP-MERFISH enables whole-transcriptome-scale, isoform-resolved spatial imaging of single cells in intact tissues and reveals how gene programs and transcript isoform usage vary across cell types...

Remote activation of a single-AAV-deliverable photoswitchable Cas12f system enables precise spatial and temporal control of genome editing in deep tissues without surgery or implanted devices.

Most primates have a large, highly folded (gyrencephalic) neocortex, a feature present in the primate common ancestor. In contrast, several New World monkey species display a comparatively small and l...